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2010

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Potential Chemical Defenses Against Diatom Fouling In Macroalgae From The Antarctic Peninsula: Insights From Bioassay Guided Fractionation, Hamel P. Sevak Jan 2010

Potential Chemical Defenses Against Diatom Fouling In Macroalgae From The Antarctic Peninsula: Insights From Bioassay Guided Fractionation, Hamel P. Sevak

All ETDs from UAB

No abstract provided.


Racial Disparities In Healthcare Utilization Betwee N African Americans And Caucasians With Mild Cognitve Impairment, Bridgett P. Hill Jan 2010

Racial Disparities In Healthcare Utilization Betwee N African Americans And Caucasians With Mild Cognitve Impairment, Bridgett P. Hill

All ETDs from UAB

No abstract provided.


An Assessment Of The Factors That Affect The Self-Care Behaviors Of Diabetics, Gregory Ellis Jan 2010

An Assessment Of The Factors That Affect The Self-Care Behaviors Of Diabetics, Gregory Ellis

All ETDs from UAB

various heteroskedastic analysis of covariance (ANCOVA) models with orthogonal


Maternal Gestational Glucose Concentration And Offspring Body Composition, Insulin Sensitivity, And Ss-Cell Function, Nikki C. Bush Jan 2010

Maternal Gestational Glucose Concentration And Offspring Body Composition, Insulin Sensitivity, And Ss-Cell Function, Nikki C. Bush

All ETDs from UAB

Background: Evidence suggests that intrauterine exposure to elevated glucose concentrations may be a mediating factor in prenatal programming of offspring disease risk. However, studies examining the effects of maternal glucose concentration on measures of body composition, insulin sensitivity, and ß-cell response in prepubertal children are limited. Therefore, the objective of this study was to determine the associations of maternal glucose concentration with children's fat mass, insulin sensitivity, and ß-cell response using robust and physiologic measures. Methods: Participants were 40 children aged 5-10 years. Children's insulin sensitivity index (SI) and measures of basal, static, dynamic, and total ß-cell response were determined …


Diversity, Commonality, And Stability Of Mutans Streptococci In High Caries Risk Children, Kyounga Cheon Jan 2010

Diversity, Commonality, And Stability Of Mutans Streptococci In High Caries Risk Children, Kyounga Cheon

All ETDs from UAB

Mutans streptococci (MS), Streptococcus mutans and Streptococcus sobrinus are associated with the initiation of dental caries in humans. Initially, a single S. mutans genotype has been shown to colonize primary molars soon after eruption. More genotypes can be acquired with age and further dental development. Current methods used to genotype isolates from an individual have not systematically determined the minimum number required to demonstrate an individual's genetic diversity. The purpose of this study was to determine the optimum number of oral isolates of MS (i.e., from plaque samples) to genotype in order to demonstrate diversity. This study also initiated a …


Examining The Association Between Body Mass Index And Weight Related Quality Of Life In Black And White Women, Tiffany Lashaun Cox Jan 2010

Examining The Association Between Body Mass Index And Weight Related Quality Of Life In Black And White Women, Tiffany Lashaun Cox

All ETDs from UAB

Obesity not only increases risk for morbidity/mortality, but also impacts the quality of life of obese individuals. In the United States, black women have the highest prevalence of obesity of any other group with approximately 80% of black women over age 20 having a body mass index (BMI) ≥ 25 kg/m2. We aimed to examine the association between weight and quality of life in this high risk population and compare it to weight-related quality of life in white women using the Impact of Weight on Quality of Life (IWQOL)-Lite questionnaire. Data for 343 women were analyzed (172 black, 171 white). …


The Effects Of Weight Reduction On Obesity-Related Cancer Biomarkers And In Vitro Cancer Cell Growth, Maria Azrad Jan 2010

The Effects Of Weight Reduction On Obesity-Related Cancer Biomarkers And In Vitro Cancer Cell Growth, Maria Azrad

All ETDs from UAB

Obesity increases the risk for breast and endometrial cancers while weight loss reduces the risk for these cancers. One aim of this dissertation was to determine the effects of weight loss from an overweight state [body mass index (BMI) 27-30] to a normal weight state on several obesity-related cancer biomarkers in African-American (AA) and European-American (EA) premenopausal women. We also sought to determine whether the method of weight loss, caloric restriction alone (CR) or combined with exercise resulted in similar changes in cancer biomarkers. The biomarkers of interest were urinary estrogen metabolites, and serum adiponectin, leptin, insulin-like growth factor (IGF)-1, …


The Role Of Post-Translational Modifications And Valosin-Containing Protein In The Turnover And Stability Of The Microtubule-Associated Protein Tau, Philip James Dolan Jan 2010

The Role Of Post-Translational Modifications And Valosin-Containing Protein In The Turnover And Stability Of The Microtubule-Associated Protein Tau, Philip James Dolan

All ETDs from UAB

Alzheimer Disease (AD) is pathologically characterized by the appearance of senile plaques composed of ß-amyloid and neurofibrillary tangles composed of the microtubule-associated protein tau. During the development of AD pathology, tau is hyperphosphorylated and aberrantly cleaved, both of which potentially contribute to its pathogenic and fibrillogenic nature. The accumulative nature of these post-translational products, and their contribution to tau pathology, has led to a great deal of study regarding mechanisms for both the maintenance of tau stability and degradation. The first part of this study reviews the developments regarding the contribution of phosphorylated tau to different physiological and pathological processes. …


Self-Blood Pressure Monitoring, Stage Of Change, Medication Adherence, Self-Efficacy And Blood Pressure Control In Hypertensive Workers, Tonya Lynn Breaux-Shropshire Jan 2010

Self-Blood Pressure Monitoring, Stage Of Change, Medication Adherence, Self-Efficacy And Blood Pressure Control In Hypertensive Workers, Tonya Lynn Breaux-Shropshire

All ETDs from UAB

ABSTRACT According to the World Health Organization, hypertension is the leading cause of death in the world and it is one of the primary reasons patients seek health care. Prior to 2010, uncontrolled blood pressure (BP) rates were approximately 18%, despite the fact that prescribed medical treatment is available to adequately control patients' BP. It has been established that medication adherence is a major factor in controlling BP, and self-BP monitoring is highly recommended by the national guideline to improve blood pressure control. However, information related to assessing hypertensive patients' readiness to engage in health care treatment and self-monitoring is …


Methods For Estimating Mediation Effect In Survival Analysis: Does Weight Loss Mediate The Undernutrition-Mortality Relationship In The Older Adults?, Yanhui Sun Jan 2010

Methods For Estimating Mediation Effect In Survival Analysis: Does Weight Loss Mediate The Undernutrition-Mortality Relationship In The Older Adults?, Yanhui Sun

All ETDs from UAB

The influence of undernutrition on mortality and other adverse outcomes through the mechanism of unintentional weight loss in older adults is often assumed, but the analytic methods to test these mediation mechanisms are not well-developed, and the need for methodological advances in this area motivated this program of research. We first examined the test-retest reliability and predictive validity of self-reported caloric intake as a measure of undernutrition. Acceptable reliability was observed, consistent with previous reports, but the evidence for predictive validity was inconsistent and self-reported caloric intake deficiency was not found to be related to observed weight loss. We then …


Identification And Characterization Of Virulence Factors Of Mycoplasmas, Wenyi Luo Jan 2010

Identification And Characterization Of Virulence Factors Of Mycoplasmas, Wenyi Luo

All ETDs from UAB

Mycoplasmas cause a group of diseases that are characterized by their chronicity and resistance to treatment. Diseases caused by the murine pathogens Mycoplasma pulmonis and Mycoplasma arthritidis are often studied as models of human diseases caused by a variety of chronic pathogens that induce a similar pathology. Among several candidate pathogenic factors, superantigens and degradative enzymes such as glycosidases are potentially important but not well characterized. The M. arthritidis mitogen (MAM) is a superantigen secreted by M. arthritidis. Its role with respect to arthritogenicity and toxicity is unclear. To improve the efficiency of transformation and hence enhance efforts to generate …


Translocation And Function Of Akt In The Mitochondria, Keri A. Mans Jan 2010

Translocation And Function Of Akt In The Mitochondria, Keri A. Mans

All ETDs from UAB

The ubiquitously expressed kinase Akt is a known survival protein, and is involved in multiple cell signaling cascades, notably the phosphatidylinositol 3-kinase (PI3K) pathway. Active Akt translocates from the plasma membrane to different subcellular compartments, including mitochondria, where it phosphorylates compartment-specific substrates. The mechanism of this translocation and the specific function of Akt within the mitochondria remains a mystery. The goals of this study were to elucidate the mechanism by which Akt enters the mitochondria and examine the role of Akt in mitochondrial function. Finally, the possibilities of using post-mortem human brain tissue to study mitochondrial function in normal and …


Translation Initiation Signaling Components Altered By Mechanical Load Dictate Skeletal Muscle Hypertrophy, David Lawrence Mayhew Jan 2010

Translation Initiation Signaling Components Altered By Mechanical Load Dictate Skeletal Muscle Hypertrophy, David Lawrence Mayhew

All ETDs from UAB

The regulation of protein synthesis (i.e., mRNA translation) is an energetically costly and extensively regulated process, which is primarily regulated at the initiation step. Mechanical load is a potent stimulus of translation in skeletal muscle, and thus this tissue provides an excellent model system to study the plasticity of the translational apparatus. We investigated the effects of alterations in translation initiation cell signaling pathways in skeletal muscle using a variety of in vitro and in vivo mouse and human model systems. Collectively, our results suggest that, although many proteins in translational signaling pathways are responsive to mechanical load, the response …


Genotyping Of Streptococcus Mutans Using Multilocus Sequence Typing, Stephanie Momeni Jan 2010

Genotyping Of Streptococcus Mutans Using Multilocus Sequence Typing, Stephanie Momeni

All ETDs from UAB

ABSTRACT The role of Streptococcus mutans has been extensively studied using a variety of genotyping techniques. Repetitive extragenic palindromic polymerase chain reaction (rep-PCR) is an effective tool for screening large-scale epidemiological studies with high discriminatory power and reproducibility. For this study, multilocus sequence typing (MLST) analysis is used to evaluate genotypes previously identified as unique using rep-PCR. Twenty-two unique S. mutans rep- PCR genotypes were selected from a longitudinal study. Four additional isolates were selected from each genotype group of the 6 most commonly occurring genotypes (n=30) for further analysis. Real-time PCR was performed using eight housekeeping S. mutans gene …


The Role Of Parental Autonomy Support In The Motivation Of The Health Behaviors Of Diet And Exercise In Older Adolescents, Shannon A. Morrison Jan 2010

The Role Of Parental Autonomy Support In The Motivation Of The Health Behaviors Of Diet And Exercise In Older Adolescents, Shannon A. Morrison

All ETDs from UAB

regardless of the degree of heteroskedasticity. Moreover, in the presence of high leverage


Assessing Knowledge, Attitudes, And Beliefs Of Teachers In Alabama Concerning Comprehensive Hiv Education, Steven Brent Powell Jan 2010

Assessing Knowledge, Attitudes, And Beliefs Of Teachers In Alabama Concerning Comprehensive Hiv Education, Steven Brent Powell

All ETDs from UAB

The Alabama State Department of Education has guidelines for educators to insure HIV information is taught by teachers starting in fifth grade (Alabama Course of Study: Health Education, 2009). As assessed by The School Health Profile (Profiles), 55% of Alabama teachers received professional development on HIV/AIDS. In addition, less than half of grades 9-12 teachers taught how condoms work, the importance of consistent condom use, and how to obtain condoms (U.S. Department of Health and Human Services, 2009). The Youth Risk Behavior Surveillance Survey (YRBSS) administered to grades 9-12 determined that 57% of youth in Alabama are sexually active, with …


The Influence Of Self-Concept, Physical Activity, And Sedentary Screen Time Activities On Blood Pressure In 11-13 Year Old Middle School Children, Elizabeth Di Benedetto Gulledge Jan 2010

The Influence Of Self-Concept, Physical Activity, And Sedentary Screen Time Activities On Blood Pressure In 11-13 Year Old Middle School Children, Elizabeth Di Benedetto Gulledge

All ETDs from UAB

The aims of this study were to: 1) examine associations between self-concept (SC), physical activity (PA), sedentary screen time (SST), and blood pressure (BP) and 2) determine the amount of variance explained by SC, PA, and SST in BP. The increase in SST along with decreases in PA may contribute to increases in BP. SC, PA and SST have been associated with BP in adolescents but less is known about middle school children. A sample of 116 (36 males; 80 females; 51 African American, 65 White) 6th and 7th grade11-13 year old students were recruited in a southeastern state. Participants …


Information Technology And Quality Of Care In Pediatric Hospitals, Gouri Gupte Jan 2010

Information Technology And Quality Of Care In Pediatric Hospitals, Gouri Gupte

All ETDs from UAB

The purpose of this dissertation is to examine the relationship between the adoption of information technology by pediatric hospitals and performance on several quality of care measures. This research is aimed at addressing a gap in literature by utilizing a relatively large sample size that examines health information technology adoption across institutions and utilizes validated quality indicators from Agency for Healthcare Research and Quality. The Donabedian evaluation model that encompasses "structure, process, and outcomes" provides the conceptual framework for the organization of this research, selection of variables, and analysis. Three secondary datasets were used, 2005 Information Technology Survey of the …


A Pilot Study For A Computer-Tailored Program To Increase Calcium And Vitamin D Consumption In Young Women: Does Adding Quantitative Ultrasound Change Outcomes?, Donald Henry Lein Jan 2010

A Pilot Study For A Computer-Tailored Program To Increase Calcium And Vitamin D Consumption In Young Women: Does Adding Quantitative Ultrasound Change Outcomes?, Donald Henry Lein

All ETDs from UAB

Osteoporosis and osteoporosis-related fractures are costly personal and national problems. No cure exists so experts stress early practice of bone protective behaviors, like adequate calcium and vitamin D intake, to prevent osteoporosis and osteoporosis-related fractures. However, young women in the United States do not consume adequate amounts of these two nutrients. Further evaluation to identify cost effective programs to increase calcium and vitamin D consumption in young women is needed. The purpose of this study was to evaluate whether quantitative ultrasound (QUS) with bone strength feedback to a computer-tailored feedback and counseling intervention was needed to increase calcium and vitamin …


Fertility Enhancing Drugs, Assisted Reproductive Technologies And Effects On Maternal And Infant Outcomes Among Live Births In Texas, Suzanne Jay Roseman Jan 2010

Fertility Enhancing Drugs, Assisted Reproductive Technologies And Effects On Maternal And Infant Outcomes Among Live Births In Texas, Suzanne Jay Roseman

All ETDs from UAB

Most studies evaluating outcomes among infertility treatment users use a spontaneously conceived (SC) group for comparative purposes, despite obvious limitations to this approach. Further, lack of comprehensive U.S. data-sources recording infertility treatments, especially non-assisted reproductive technology (non-ART) infertility treatments, has hampered the ability of U.S. researchers to explore the effects of a particular infertility treatment modality (for example ART) on maternal and infant outcomes while controlling for the effects of infertility itself. The present study makes use of the new data item: "Pregnancy resulted from infertility treatment," further categorized into ART and non-ART infertility treatments--from the 2003 revision of birth …


Drawing A Bath: Works By Robert Henri And George Bellows At The Birmingham Museum Of Art, Mary K. Russell Jan 2010

Drawing A Bath: Works By Robert Henri And George Bellows At The Birmingham Museum Of Art, Mary K. Russell

All ETDs from UAB

This thesis discussing bathing images by Robert Henri and George Bellows located at the Birmingham Museum of Art.


The Pipeline Project: Trajectories Of Classroom Behaviour And Academic Progress : A Study Of Student Engagement With Learning, Max Angus, Tim Mcdonald, Chris Ormond, Rudy Rybarcyk, Anthea Taylor, Anne Winterton Jan 2010

The Pipeline Project: Trajectories Of Classroom Behaviour And Academic Progress : A Study Of Student Engagement With Learning, Max Angus, Tim Mcdonald, Chris Ormond, Rudy Rybarcyk, Anthea Taylor, Anne Winterton

Research outputs pre 2011

The Pipeline Project addresses three questions concerning the relationship between the classroom behaviour of students and their academic performance. First, to what extent does classroom behaviour explain why students fall behind and fail to meet acceptable standards in literacy and numeracy; second, if student classroom behaviour does influence academic performance, what forms of classroom behaviour are of most significance; and third, are the students whose behaviour has contributed to their underperformance in literacy and numeracy likely to ever catch up?


Calcium Intake In Elderly Australian Women Is Inadequate, Xingqiong Meng, Deborah A. Kerr, Kun Zhu, Amanda Devine, Vicky Solah, Colin W. Binns, Richard L. Prince Jan 2010

Calcium Intake In Elderly Australian Women Is Inadequate, Xingqiong Meng, Deborah A. Kerr, Kun Zhu, Amanda Devine, Vicky Solah, Colin W. Binns, Richard L. Prince

Research outputs pre 2011

The role of calcium in the prevention of bone loss in later life has been well established but little data exist on the adequacy of calcium intakes in elderly Australian women. The aim of this study was to compare the dietary intake including calcium of elderly Australian women with the Australian dietary recommendation, and to investigate the prevalence of calcium supplement use in this population. Community-dwelling women aged 70–80 years were randomly recruited using the Electoral Roll for a 2-year protein intervention study in Western Australia. Dietary intake was assessed at baseline by a 3-day weighed food record and analysed …


An Examination Of The Association Of Selected Toxic Metals With Total And Central Obesity Indices: Nhanes 99-02, Miguel A. Padilla, Mai Elobeid, Douglas M. Ruden, David B. Allison Jan 2010

An Examination Of The Association Of Selected Toxic Metals With Total And Central Obesity Indices: Nhanes 99-02, Miguel A. Padilla, Mai Elobeid, Douglas M. Ruden, David B. Allison

Psychology Faculty Publications

It is conceivable that toxic metals contribute to obesity by influencing various aspects of metabolism, such as by substituting for essential micronutrients and vital metals, or by inducing oxidative stress. Deficiency of the essential metal zinc decreases adiposity in humans and rodent models, whereas deficiencies of chromium, copper, iron, and magnesium increases adiposity. This study utilized the NHANES 99-02 data to explore the association between waist circumference and body mass index with the body burdens of selected toxic metals (barium, cadmium, cobalt, cesium, molybdenum, lead, antimony, thallium, and tungsten). Some of the associations were significant direct relationships (barium and thallium), …


Endocrine Disruptors And Obesity: An Examination Of Selected Persistent Organic Pollutants In The Nhanes 1999-2002 Data, Mai A. Elobeid, Miguel A. Padilla, David W. Brock, Douglas M. Ruden, David B. Allison Jan 2010

Endocrine Disruptors And Obesity: An Examination Of Selected Persistent Organic Pollutants In The Nhanes 1999-2002 Data, Mai A. Elobeid, Miguel A. Padilla, David W. Brock, Douglas M. Ruden, David B. Allison

Psychology Faculty Publications

Recent evidence suggests that endocrine disrupting chemicals (EDCs) may cause perturbations in endogenous hormonal regulation that predispose to weight gain. Using data from NHANES (1999-2002), we investigated the association between body mass index (BMI), waist circumference (WC) and selected persistent organic pollutants (POPs) via multiple linear regressions. Consistent interaction was found between gender, ln oxychlordane and ln p,p' DDT. Also, we found an association between WC and ln oxychlordane and ln hpcdd in subjects with detectable levels of POPs, whereas an association between WC and ln p,p' DDT was observed in all subjects. Furthermore, ln Ocdd showed an increase with …


Unfurling Fern Biology In The Genomics Age, M. S. Barker, Paul G. Wolf Jan 2010

Unfurling Fern Biology In The Genomics Age, M. S. Barker, Paul G. Wolf

Biology Faculty Publications

Twenty-first century technology is addressing many of the questions posed by 20th-century biology. Although the new approaches, especially those involving genomic data and bioinformatic tools, were first applied to model organisms, they are now stretching across the tree of life. Here, we review some recent revelations in the ferns. We first examine how DNA sequence data have contributed to our understanding of fern phylogeny. We then address evolution of the fern plastid genome, including reports of high levels of RNA editing. Recent studies are also shedding light on the evolution of fern nuclear genomes. Initial analyses of genomic data suggest …


Determination Of Optimal Dose Of Egf For Bovine Oocyte Maturation And Subsequent In Vitro Fertilization And Culture In Two Media, Ayhan Baştan, Bülent Polat, Duygu Baki̇ Acar, Ömer Korkmaz, Armağan Çolak Jan 2010

Determination Of Optimal Dose Of Egf For Bovine Oocyte Maturation And Subsequent In Vitro Fertilization And Culture In Two Media, Ayhan Baştan, Bülent Polat, Duygu Baki̇ Acar, Ömer Korkmaz, Armağan Çolak

Turkish Journal of Veterinary & Animal Sciences

The aim of this study was to determine the optimal dose of EGF on in vitro maturation of bovine oocytes and to investigate the effect of different IVF and IVC media on development of bovine embryos matured with EGF. Oocytes collected from a slaughterhouse were randomly divided into 4 groups. Each group of oocytes was incubated with different doses of EGF (Control: 0 ng/mL, Group 1: 1 ng/mL, Group 2: 10 ng/mL, and Group 3: 100 ng/mL) for 24 h to determine the optimal dose. Matured oocytes were fertilized with frozen-thawed bull sperm by using the swim-up method. The oocytes …


Comparative Efficacy Of Seven Brands Of Albendazole Against Naturally Acquired Gastrointestinal Nematodes In Sheep In Hawassa, Southern Ethiopia, Bersissa Kumsa, Adugna Tolera, Ajebu Nurfeta Jan 2010

Comparative Efficacy Of Seven Brands Of Albendazole Against Naturally Acquired Gastrointestinal Nematodes In Sheep In Hawassa, Southern Ethiopia, Bersissa Kumsa, Adugna Tolera, Ajebu Nurfeta

Turkish Journal of Veterinary & Animal Sciences

This study aimed to evaluate the efficacy of 7 brands of albendazole against gastrointestinal nematodes in naturally infected sheep in southern Ethiopia. The study included 120 local breed male sheep purchased in Hawassa. The sheep were divided into 8 groups of 15 animals each. Group 1 served as the untreated control, whereas groups 2-8 were treated with ABZ1, ABZ2, ABZ3, ABZ4, ABZ5, ABZ6, and ABZ7, respectively. Fecal samples were collected before treatment on day 0, and again on post-treatment day 12. The efficacy of all 7 brands of albendazole was determined on post-treatment day 12 based on the fecal egg …


Prevalence And Antimicrobial Resistance Of Salmonella Serovars Isolated From Poultry Meat In Hyderabad, Pakistan, Aijaz Hussain Soomro, Muhammad Khaskheli, Muhammad Bachal Bhutto, Ghiasuddin Shah, Azizullah Memon, Parkash Dewani Jan 2010

Prevalence And Antimicrobial Resistance Of Salmonella Serovars Isolated From Poultry Meat In Hyderabad, Pakistan, Aijaz Hussain Soomro, Muhammad Khaskheli, Muhammad Bachal Bhutto, Ghiasuddin Shah, Azizullah Memon, Parkash Dewani

Turkish Journal of Veterinary & Animal Sciences

This study was conducted to investigate the prevalence of Salmonella in broiler chicken meat sold in Hyderabad, Pakistan. A total of 100 samples were randomly collected from poultry meat retail markets and examined for the presence of Salmonella. The prevalence rate recorded was 38%. The most prevalent serogroups were S. enteritidis, S. typhi, S. pullorum, and S. typhimurium. All the Salmonella isolates showed resistance to ampicillin, and sensitivity to tetracycline, streptomycin, cefotaxime, ceftazidime, gentamicin, tobramycin, ciprofloxacin, ofloxacin, and chloramphenicol. The findings highlighted the magnitude of Salmonella contamination in chicken meat sold in the city, and the antibiotic resistance of Salmonella …


Recess Policy In Chicago Public Schools: 1855-2006, Laura Ann Wurzburger Jan 2010

Recess Policy In Chicago Public Schools: 1855-2006, Laura Ann Wurzburger

Master's Theses

The history of Chicago Public Schools (CPS) recess policy has been marked by long periods of consistency. However, in the last two decades the history of recess policy has changed significantly. Beginning in the mid-19th century, the Board of Education required one to two recess sessions per day in primary or elementary schools. This is in stark contrast to the 1991 policy which eliminated recess entirely for seven years. In 1998 there was another policy shift which is still in effect today. This policy allows individual principals and their local school councils to determine how to allocate their daily schedule. …