Digital Commons Network^™

Low Cost Production Of Proinsulin In Tobacco And Lettuce Chloroplasts For Injectable Or Oral Delivery Of Functional Insulin And, Diane Burberry

Electronic Theses and Dissertations

Current treatment for type I diabetes includes delivery of insulin via injection or pump, which is highly invasive and expensive. The production of chloroplast-derived proinsulin should reduce cost and facilitate oral delivery. Therefore, tobacco and lettuce chloroplasts were transformed with the cholera toxin B subunit fused with human proinsulin (A, B, and C peptides) containing three furin cleavage sites (CTB-PFx3). Transplastomic lines were confirmed for site-specific integration of transgene and homoplasmy. Old tobacco leaves accumulated proinsulin up to 47% of total leaf protein (TLP). Old lettuce leaves accumulated proinsulin up to 53% TLP. Accumulation was so stable that up to …

But This Is What I See; This Is What I See: Re-Imagining Gendered Subjectivity Through The Woman Artist In Phelps, Johnstone, And Woolf, Heather Wayne

Electronic Theses and Dissertations

Since the publication of Laura Mulvey's influential article 'Visual Pleasure and Narrative Cinema,' in which she identifies the pervasive presence of the male gaze in Hollywood cinema, scholars have sought to account for the female spectator in her paradigm of gendered vision. This thesis suggests that women writers have long debated the problem of the female spectator through literary depictions of the female artist. Women writers of the nineteenth and twentieth centuries'including Elizabeth Stuart Phelps, Edith Johnstone, and Virginia Woolf'recognized the power of the woman artist to undermine the trope of the male gazing subject and a passive female object. …

Understanding The Female Conceptualization Of Sexual Addiction And The Role Of Addiction Treatment, Megan Douglass

Electronic Theses and Dissertations

Beginning with the diagnosis of nymphomania in the 19th Century, there has been widespread and continued interest across the mental health and bio-medical realm of what constitutes normality of female sexual behavior, and of the boundary at which sexual desire is deemed to be excessive, and thus abnormal. However, research questions that specifically investigate the subjective female voice and perspective in considerations of so-called hypersexuality or sex addiction remain understudied. This research project proposes to examine the cultural pathways and systemic foundations which have historically in the West problematized female sexuality by investigating women's own perceptions of sexual addiction and …

Paleopathology In Ancient Eygpt: Evidence From The Sites Of Dayr Al-Barsha And Sheikh Said, Cindy Malnasi

Electronic Theses and Dissertations

For centuries, people have been fascinated with how the ancient Egyptians lived, and particularly how they died. Although Egyptologists in the past had a greater interest in the treasures that accompanied the dead, there has now been a shift in focus on the actual ancient Egyptians themselves and their ways of life. Recognizing the health and disease status of ancient Egyptians has become particularly important. The aim of this research project is to document the paleopathology of the individuals from the sites of Dayr al-Barsha and Sheikh Said encompassing the Old Kingdom (2686 - 2160 BC), the First Intermediate Period …

Engineering A New Form Of Enclosure: International Convergence In Gmo Regulation, Jessica Altif

Electronic Theses and Dissertations

As society begins to recognize its impact on ecological systems, the belief that modern political institutions can offer a sense of control and certainty, as well as protect the health of its citizens, is increasingly questioned. In an era of uncertainty, faith in science and technology to alleviate industrial impacts on the environment is often embraced by policymakers yet questioned by the public who see the authoritative role of the sciences in the political sphere as contributing to global risk. The development of biotechnology, specifically genetically modified food, places an anthropocentric focus on resolving and/or adapting to environmental degradation, further …

Have Nominating Conventions Lost Power?, Tyler Branz

Electronic Theses and Dissertations

Do conventions still have relevance in the modern political world? Some call them glorified television infomercials for presidential candidates while others refer to them as admired pillars of American political history. Whichever viewpoints one identifies with, presidential conventions are interesting to study historically, and can be studied analytically. The following case studies examine the institution of the nominating convention: what they do, how they form, what they have accomplished and how they affect the voters. This study finds that conventions are still meaningful in American politics, particularly for affecting party unity, candidate image and, to a lesser degree, party platform.

The Response Of Administrators And Instructors In The Orange County, Florida Public High School System To Dating Violence Preven, Denise Crisafi

Electronic Theses and Dissertations

Adolescent dating violence occurs in high schools at an alarming rate. To educate adolescents about dating violence, some public high schools have incorporated prevention programs into their curriculum. These programs, which are predicated upon empiricism and behavioral theories, tend to produce limited results. In order to improve prevention programs, it has been suggested that schools should play a larger role in their development and implementation. However, dating violence studies have yet to examine how much school personnel know about adolescent dating violence and prevention strategies. The current study surveyed administrators and instructors at six public high schools in Orange County, …

A Content Analysis Of Elite U.S. Newspapers' Coverage Of Iran, 1979 And 2005, Melissa Kamal

Electronic Theses and Dissertations

This study is a quantitative content analysis of the New York Times and Washington Post coverage of Iran during the period surrounding the Ayatollah Khomeini's ascension to power in 1979 as well as the period surrounding Mahmoud Ahmadinejad's election in 2005. The results showed that coverage of Iran in the elite American print media as it related to terror was higher in the period after Khomeini came to power and also in the period after Ahmadinejad's election than it was in the period immediately preceding their respective ascensions. The results also showed that there was more coverage of Iran as …

Source Representation And Framing In Childhood Immunization Communication, April Raneri

Electronic Theses and Dissertations

Research has indicated a strong interest in knowing who is being represented and how information is being represented in the communication about childhood immunization. This study uses a two-part analysis to look at source representation and framing in childhood immunization communication. A quantitative analysis of articles from the New York Times and USA Today were examined for their source representation, their use of fear appeals, through the Extended Parallel Processing Model (EPPM), and the use of frames, through the application of Prospect Theory. A qualitative semiotic analysis was conducted on 36 images that appeared on www.yahoo.com and www.google.com to find …

Perceptions On The Social Status Of Papiamentu In Contrast To Its Offical Significance In Aruba And Curacao, Keisha Wiel

Electronic Theses and Dissertations

Many creole languages have been studied by linguists and anthropologists alike in order to gain a better understanding as to their formations and social status within their respective cultures. Theories such as the Language Bioprogram hypothesis created by Derek Bickerton researched explicitly the genesis of creoles, primarily the creoles in Guyana and Hawaii. Although many creole languages are the main vernaculars of many cultures, they are often seen as having a lower status than the official language, usually a European language. Papiamentu, a language spoken in Aruba, Curacao, and Bonaire, has carried a prestige that many other creoles do not …

Understanding Terrorism: Religious & Political Dimensions, Christopher Cusano

Electronic Theses and Dissertations

Terrorism in the twenty-first century has had one of greatest effects on the status quo of international relations, peace and war. It has become the 'specter' of our era and in many instances, it has been referred to as the predominant threat of modern civilization. Furthermore, it has the potential to drastically change the world we live in. For these reasons it has rightfully earned our attention and focus. Many efforts to understand terrorism have fallen short of recognizing the underlying causes. In many cases, acts of terror have either been of purely political motivation or have had socioeconomic conditions …

Evaluation Of An Expectancy Challenge Presentation In Reducing High-Risk Alcohol Use Among Greek Affiliated College Students, Abigail Fried

Electronic Theses and Dissertations

Alcohol consumption and on college campuses has long been a significant problem. The severity of the situation and lack of effective alcohol programming on college campuses warranted the National Institute on Alcohol Abuse and Alcoholism to commission a Task Force on College Drinking in 2002, which has been vital in revealing drinking patterns and negative consequences which are specific to the college environment. The Task Force proposed three strategies that were empirically validated for prevention and intervention in the college setting. Of the three recommendations, implementing cognitive behavioral skills training and offering motivational enhancement interventions, while proven effective are costly …

Muslims In The Media:The New York Times From 2000 - 2008, Autumn Bishop

Electronic Theses and Dissertations

Although it is widely recognized that Muslims and Middle Easterners were negatively portrayed in the media after the terrorist attacks on September 11, 2001, few scholars examine the long term media presentations of Islam in the United States. The studies that have explored the relationship of the portrayal of Islam by the media have used short term, limited sampling techniques, which may not properly reflect the popular media as a whole. The current research uses data from the New York Times from 2000-2008 in order to determine whether the popular media was portraying Islam in a disparaging manner. The analysis …

A Qualitative Investigation Of Adolescent Females' Use Of Social Networking Websites, Janine Pate

Electronic Theses and Dissertations

The aim of the present study was to explore the ways adolescent females, age 14 through 17, utilized social networking websites such as MySpace and Facebook for communication, self-presentation and identity development purposes. Uses and gratifications theory served as a framework for identifying the participants' motivations for heavily using these websites, which allow users to post pictures, interests and updates for their friends to view and interact with online. Using a qualitative method, one preliminary focus group and ten in-depth interviews were conducted, totaling fifteen female participants between the ages of 14 and 17. Interview questions covered topics such as …

Student Digital Piracy In The Florida State University System:An Exploratory Study On Its Infrastructural Effects, Jeffrey Reiss

Electronic Theses and Dissertations

Digital piracy is a problem that may never disappear from society. Through readily available resources such as those found in a university, students will always have access to illegal goods. While piracy is a global phenomenon, an institution's resources combined with the typical college student's lack of funds makes it more lucrative. Students use a number of methods to justify their actions ranging from previewing media to bringing justice to a corrupt company. While trying to understand the mindset of pirates is one route to deal with piracy, corporations attempted to alleviate the situation using added software encoding. These messages …

Fast Response Dual Frequency Liquid Crystal Materials, Qiong Song

Electronic Theses and Dissertations

Dual frequency liquid crystal (DFLC) exhibits a positive dielectric anisotropy at low frequencies and negative dielectric anisotropy at high frequencies. The frequency where dielectric anisotropy is zero is called crossover frequency. DFLC can achieve fast rise time and fast decay time with the assistance of applied voltage. However, one drawback of DFLC is that it has dielectric heating effect when driven at a high frequency. Thus, the first part of this dissertation is to develop low crossover frequency DFLC materials. The dielectric relaxation and physical properties of some single- and double-ester compounds were investigated. Experimental results indicate that the double-ester …

Machinima And Video-Based Soft Skills Training, Curtis Conkey

Electronic Theses and Dissertations

Multimedia training methods have traditionally relied heavily on video based technologies and significant research has shown these to be very effective training tools. However production of video is time and resource intensive. Machinima (pronounced 'muh-sheen-eh-mah') technologies are based on video gaming technology. Machinima technology allows video game technology to be manipulated into unique scenarios based on entertainment or training and practice applications. Machinima is the converting of these unique scenarios into video vignettes that tell a story. These vignettes can be interconnected with branching points in much the same way that education videos are interconnected as vignettes between decision points. …

Integrating Universal Design For Learning Concepts Into Secondary General Education Instructional Methods Courses, Kimberly Pawling

Electronic Theses and Dissertations

Because many general education teachers feel unprepared to provide students with disabilities with appropriate instruction, changes to teacher education programs are needed (Burdette, 2007; Smith et al., 2010). Teacher education programs need to integrate content regarding instructional methods for teaching and accommodating students with disabilities in secondary, general education classrooms (Burdette, 2007; Smith et al., 2010). The results of the research should provide insight (1) to determine if integrating instruction on UDL into preservice SGE students' instructional methods courses will increase students' knowledge of UDL and (2) to determine if integrating instruction on Universal Design for Learning (UDL) will affect …

Privacy As Product Safety, James Grimmelmann

Cornell Law Faculty Publications

Online social media confound many of our familiar expectations about privacy. Contrary to popular myth, users of social software like Facebook do care about privacy, deserve it, and have trouble securing it for themselves. Moreover, traditional database-focused privacy regulations on the Fair Information Practices model, while often worthwhile, fail to engage with the distinctively social aspects of these online services.

Instead, online privacy law should take inspiration from a perhaps surprising quarter: product-safety law. A web site that directs users' personal information in ways they don't expect is a defectively designed product, and many concepts from products liability law could …

A Comparison Between The Verbal Interruptions By Speakers Of English As A Lingua Franca (Elf) And Speakers Of English As A Native Language (Enl), Yue Yuan Li

Lingnan Theses

Previous research focused primarily on how interruptions vary according to social factors in situations where English is the native language for all speakers (see Menz and Al-Roubaie, 2008; O‟Reilly, 2008; West and Zimmerman, 1983; Zimmerman and West, 1975). Little has been done on interruptions in situations where English is used as a lingua franca. The purpose of this research is to 1) provide conversational evidence on how experienced ELF speakers make interruptions, 2) explore functions of interruptions in ELF communication; 3) compare the types and functions of interruptions in ELF communication with those in ENL communication; 4) compare the types …

Fragmented Authoritarianism And Politics Of Hydropower In China : Case Studies Of Tgp & Nrp, Miu Fai, Tommy Wong

Lingnan Theses

Thanks for economic improvements since the ‘open-door policy’ in 1978; China’s international status has been improving economically and even politically. For instance, she has become a major contributor of BRIC which is a group of four most rapidly developing countries in the world, i.e. Brazil, Russia, India and China, and the largest buyer of U.S. treasury bonds in the world. Nevertheless, a number of intellectuals like Liu and Shirk pointed out that there are still a number of difficulties – both exogenous and endogenous – underneath.1 This research would like to concentrate on one of the aspects which Chinese investigators …

Consequences Of Increased Cd45ra And Rc Isoforms For Tcr Signaling And Peripheral T Cell Deficiency Resulting From Heterogeneous Nuclear Ribonucleoprotein L-Like Mutation, Zuopeng Wu, Adele L. Yates, Gerard F. Hoyne, Christopher C. Goodnow

Health Sciences Papers and Journal Articles

CD45 is the most abundant protein tyrosine phosphatase in the plasma membrane of T cells and serves a critical role in TCR signaling. Different CD45 isoforms are made by alternative mRNA splicing depending on the stage of T cell development and activation, yet their role remains unclear. Expression of CD45RA and RC isoforms is increased 20- to 200-fold on T cells from thunder mice with a loss-of-function mutation in the RNA-binding protein, heterogeneous nuclear ribonucleoprotein L-like (hnRNPLL), although total CD45 expression is unaltered. In this study, we test the hypothesis that this shift in CD45 isoform expression alters TCR signaling, …

The Impact Of Universal Design For Learning-Representation Practices On Concept Maps And The Development Of Quality Scientific Explanations, Lisa A. Finnegan

Electronic Theses and Dissertations

The purpose of this action research project was to determine how my practice of implementing Universal Design for Learning-Representation (UDL-R) principles influenced my students’ understanding of content and enhanced their ability to organize their knowledge using concept maps. A secondary purpose of this action research project was to determine if student created concept maps served as a useful tool to enrich students’ written scientific explanations. Students in this study completed concept maps and wrote explanations about adaptations before and after participating in lessons enriched with UDL-R principles that included the use of multimedia sources, website searches, and trade books. The …

Magnetic Nanosensors For Multiplexed Bacterial Pathogenesis Identification, Charalambos Kaittanis

Electronic Theses and Dissertations

Developing diagnostic modalities that utilize nanomaterials and miniaturized detectors can have an impact in point-of-care diagnostics. Diagnostic systems that (i) are sensitive, robust, and portable, (ii) allow detection in clinical samples, (iii) require minimal sample preparation yielding results quickly, and (iv) can simultaneously quantify multiple targets, would have a great potential in biomedical research and public healthcare. Bacterial infections still cause pathogenesis throughout the world (Chapter I). The emergence of multi-drug resistant strains, the potential appearance of bacterial pandemics, the increased occurrence of bacterial nosocomial infections, the wide-scale food poisoning incidents and the use of bacteria in biowarfare highlight the …

Experimental And Theoretical Approaches To Characterization Of Electronic Nonlinearities In Direct-Gap Semiconductors, Claudiu Cirloganu

Electronic Theses and Dissertations

The general goal of this dissertation is to provide a comprehensive description of the limitations of established theories on bound electronic nonlinearities in direct-gap semiconductors by performing various experiments on wide and narrow bandgap semiconductors along with developing theoretical models. Nondegenerate two-photon absorption (2PA) is studied in several semiconductors showing orders of magnitude enhancement over the degenerate counterpart. In addition, three-photon absorption (3PA) is studied in ZnSe and other semiconductors and a new theory using a Kane 4-band model is developed which fits new data well. Finally, the narrow gap semiconductor InSb is studied with regard to multiphoton absorption, free-carrier …

Silicon-Sensitized Erbium Excitation In Silicon-Rich Silica For Integrated Photonics, Oleksandr Savchyn

Electronic Theses and Dissertations

It is widely accepted that the continued increase of processor performance requires at least partial replacement of electronic interconnects with their photonic counterparts. The implementation of optical interconnects requires the realization of a silicon-based light source, which is challenging task due to the low emission efficiency of silicon. One of the main approaches to address this challenge is the use of doping of silicon based matrices with optical centers, including erbium ions. Erbium ions incorporated in various hosts assume the trivalent state (Er3+) and demonstrate a transition at 1.54 μm, coinciding with optical transmission windows in both silicon and silica. …

Acetazolamide-Induced Decrease Of Apical Fluid Flow In Choroid Plexus Is Independent Of The Concomitant Changes In Aquaporin-1 Expression, Pouya Alexander Ameli

Electronic Theses and Dissertations

Acetazolamide (AZA), the only drug approved for treatment of hydrocephalus, is effective in only 25-30% of patients while its effect on fluid flow in the choroid plexus (CP) is unknown. The drug reversibly inhibits Aquaporin 4 (AQP4), the most highly expressed „water pore‟ in the brain, and it is postulated that it reduces cerebrospinal fluid (CSF) production by modulating AQP1 (mostly found in the apical membrane of the CP). In this study, we sought to elucidate the effect of AZA on AQP1 and fluid flow in CP. Primary CP culture from p10 Sprague-Dawley rats and TRCSF-B cell line were grown …

Design, Synthesis And Characterization Of New Two-Photon Absorbing (2pa) Fluorescent Dyes And Bioconjugates, And Their Applications In Bioimaging, Carolina D. Andrade

Electronic Theses and Dissertations

The development of new multiphoton absorbing materials has attracted the attention of researchers for the last two decades. The advantages that multiphoton absorbing materials offer, versus their one-photon absorbing counterparts, rely on the nature of the nonlinearity of the absorption process, where two photons are absorbed simultaneously offering increased 3D resolution, deeper penetration, and less photobleaching and photodamage as a result of a more confined excitation. The applications of efficient two-photon absorbing materials have been extensively expanding into the fields of photodynamic therapy, microscopy, and optical data storage. One of the fields where an increased interest in multiphoton absorbing materials …

Social Comparison, Self-Objectification, And Objectification Of Others Investigating The Vicious Cycle That Leads To Body Dissatisfaction And Disordered Eating, Danielle M. Lindner

Electronic Theses and Dissertations

The purpose of this study was to test a new theoretical model that integrates self-objectification, objectification of others, and social comparison as contributors to the development and maintenance of body image disturbance and disordered eating behavior. Within the new theoretical model, self-objectification, objectification of others, and social comparison are conceptualized as a self-perpetuating cycle, rather than as processes that occur independently of one another. Four hundred fifty-nine female college students between the ages of 18 and 32 completed measures of self-objectification, objectification of others, social comparison, body shame, body dissatisfaction, and eating disorder symptomatology. Structural equation modeling with nested model …

Dialectical Tensions Between Glocalization And Grobalization For Wal-Mart In The United States, Laura Lord

Electronic Theses and Dissertations

This qualitative analysis examines Wal-Mart managers‟ perspectives of the strategies that the U.S. corporation has implemented in order to increase its sales and profits at more than 4,000 stores in local U.S. communities. Two theoretical paradigms are specifically used: glocalization and grobalization. The former refers to cultural adaptation; the latter means standardization. The ultimate goal of the researcher is to identify the dialectical tensions between those two current forms of globalization. In-depth, face-to-face, qualitative interviewing of ten Wal-Mart managers in Central Florida allowed the researcher to actually comprehend managers‟ perspectives, gather fresh data, and construct a final product to enlighten …