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2010

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Acute Toxicity Of Diphacinone In Northern Bobwhite: Effects On Survival And Blood Clotting, Barnett A. Rattner, Katherine E. Horak, Sarah E. Warner, John J. Johnston Jan 2010

Acute Toxicity Of Diphacinone In Northern Bobwhite: Effects On Survival And Blood Clotting, Barnett A. Rattner, Katherine E. Horak, Sarah E. Warner, John J. Johnston

United States Department of Agriculture Wildlife Services: Staff Publications

The anticoagulant rodenticide diphacinone was slightly toxic (acuteoralLD50 2014 mg/kg) to Northern bobwhite (Colinus virginianus) in a 14-day acute toxicity trial. Precise and sensitive assays of blood clotting (prothrombin time, Russell’s Viper venom time, and thrombin clotting time) were adapted for use in quail, and this combination of assays is recommended to measure the effects of anticoagulant rodenticides. A single oral sub lethal dose of diphacinone (434mg/kg body weight) prolonged clotting time at 48 h post-dose compared to controls. At 783 mg/kg (approximate LD02), clotting time was prolonged at both 24 and 48 h post-dose. …


Exclusion Fencing For Feral Hogs At White-Tailed Deer Feeders, Justin M. Rattan, Billy J. Higginbotham, David B. Long, Tyler A. Campbell Jan 2010

Exclusion Fencing For Feral Hogs At White-Tailed Deer Feeders, Justin M. Rattan, Billy J. Higginbotham, David B. Long, Tyler A. Campbell

United States Department of Agriculture Wildlife Services: Staff Publications

Management programs aimed at white-tailed deer (Odocoileus virginianus) production often include the use of feeders, either to deliver supplemental feed or bait. However, much of the feed placed into deer feeders is consumed by non-target species, such as feral hogs (Sus scrofa). Our objectives were to compare three exclusion fence designs at deer feeders for their ability to restrict feral hog visitation and enable white-tailed deer visitation. Our high fence design consisted of 86 cm high graduated paneling. Our medium fence design consisted of 76 cm high, 10´10 cm paneling. Our low height design consisted of …


Experimental Exposure Of Swallow Bugs (Hemiptera: Cimicidae) To West Nile Virus, Paul T. Oesterle, Nicole M. Nemeth, Paul Doherty, Robert Mclean, Larry Clark Jan 2010

Experimental Exposure Of Swallow Bugs (Hemiptera: Cimicidae) To West Nile Virus, Paul T. Oesterle, Nicole M. Nemeth, Paul Doherty, Robert Mclean, Larry Clark

United States Department of Agriculture Wildlife Services: Staff Publications

The cliff swallow (Petrochelidon pyrrhonota, Vieillot) could potentially play an important role in the transmission of West Nile virus (WNV) because of its breeding ecology, reservoir competence status, and potentially high natural exposure rates. These birds nest in colonies and their nests are occupied year round by swallow bugs (Oeciacus vicarius, Hovarth), hematophagus ectoparasites that feed primarily on cliff swallows. Swallow bugs are most likely exposed to WNV while feeding on infectious blood of cliff swallows and, thus, if competent vectors, could contribute to initiation and maintenance of seasonal WNV transmission. In addition, swallow bugs remain …


What Tradition Teaches: Indigenous Knowledge Complements Western Wildlife Science, Paige M. Schmidt, Heather K. Stricker Jan 2010

What Tradition Teaches: Indigenous Knowledge Complements Western Wildlife Science, Paige M. Schmidt, Heather K. Stricker

United States Department of Agriculture Wildlife Services: Staff Publications

In 1977, scientific surveys indicated that bowhead whales (Balaena mysticetus) in the Beaufort Sea were in trouble, with fewer than 1,000 individuals remaining. The International Whaling Commission took action to put a moratorium on native hunts in order to protect the species. Yet local Inuit hunters didn't see what the fuss was about. Their own estimates, gleaned from time and experience, put bowhead numbers at 7,000. The Inuits also disputed western scientists' contentions that whales couldn't swim under offshore ice and that they did not feed during migration. Researchers responded to these criticisms by developing a new survey …


Epizootic Hemorrhagic Disease Outbreak In A Captive Facility Housing White-Tailed Deer (Odocoileus Virginianus), Bison (Bison Bison), Elk (Cervus Elaphus), Cattle (Bos Taurus), And Goats (Capra Hircus) In Colorado, Usa, Pauline Nol, Cecilia Kato, Will K. Reeves, Jack Rhyan, Terry R. Spraker, Thomas Gidlewski, Kurt C. Vercauteren, Mo Salman Jan 2010

Epizootic Hemorrhagic Disease Outbreak In A Captive Facility Housing White-Tailed Deer (Odocoileus Virginianus), Bison (Bison Bison), Elk (Cervus Elaphus), Cattle (Bos Taurus), And Goats (Capra Hircus) In Colorado, Usa, Pauline Nol, Cecilia Kato, Will K. Reeves, Jack Rhyan, Terry R. Spraker, Thomas Gidlewski, Kurt C. Vercauteren, Mo Salman

United States Department of Agriculture Wildlife Services: Staff Publications

An ungulate research facility in Fort Collins, Colorado, USA, experienced mortality in white-tailed deer (Odocoileus virginianus) because of epizootic hemorrhagic disease virus (EHDV) infection from 20 August 2007 through 26 September 2007. Epizootic hemorrhagic disease virus (EHDV) was detected by reverse transcriptase polymerase chain reaction and virus isolation from the spleen and lung tissues of two white-tailed deer. Virus neutralization tests were performed on pre- and post-outbreak sera from other species maintained in the same facility, including bison (Bison bison), elk (Cervus elaphus), domestic cattle (Bos taurus), and domestic goats (Capra hircus), …


Management Of Damage By Elk (Cervus Elaphus) In North America: A Review, W. David Walter, Michael J. Lavelle, Justin W. Fischer, Therese L. Johnson, Scott E. Hygnstrom, Kurt C. Vercauteren Jan 2010

Management Of Damage By Elk (Cervus Elaphus) In North America: A Review, W. David Walter, Michael J. Lavelle, Justin W. Fischer, Therese L. Johnson, Scott E. Hygnstrom, Kurt C. Vercauteren

United States Department of Agriculture Wildlife Services: Staff Publications

Abundant populations of elk (Cervus elaphus) are cherished game in many regions of the world and also cause considerable human–wildlife conflicts through depredation on agriculture and specialty crops, lack of regeneration to native ecosystems, collisions with vehicles and transmission of disease between free-ranging and farmed hoofstock. Management of elk varies, depending on current and historical agency objectives, configuration of the landscapes elk occupy, public perception, population density and behaviour of elk. Selection of the method to manage elk often requires knowledge of timing of impacts, duration relief from elk damage is desired, cost-effectiveness of management activities, tolerance of …


Laboratory Efficacy Of Chemical Repellents For Reducing Blackbird Damage In Rice And Sunflower Crops, Scott J. Werner, George M. Linz, Shelagh K. Tupper, James C. Carlson Jan 2010

Laboratory Efficacy Of Chemical Repellents For Reducing Blackbird Damage In Rice And Sunflower Crops, Scott J. Werner, George M. Linz, Shelagh K. Tupper, James C. Carlson

United States Department of Agriculture Wildlife Services: Staff Publications

Nonlethal alternatives are needed to manage blackbird (Icterids) damage to rice and sunflower production in the United States. We evaluated 4 registered fungicides on rice seeds (i.e., Allegiance® FL, Thiram 42-S, Trilex®, and Vitavax® 200 preplant seed treatments) and 2 foliar pesticides on sunflower seeds (CobaltTM insecticide and Flock Buster bird repellent) as candidate blackbird repellents. Red-winged blackbirds (Agelaius phoeniceus) preferred untreated rice relative to rice treated with Thiram (P < 0.001) and Vitavax (P < 0.001), and untreated sunflower relative to sunflower treated with Cobalt (P < 0.001). Blackbirds preferred untreated sunflower relative to sunflower treated with Flock Buster repellent on day 1 of a 4-day preference test (P < 0.001). We observed no difference in consumption of treated versus untreated rice during the Allegiance preference test (P = 0.928), and blackbirds preferred rice treated with Trilex relative to untreated rice (P = 0.003). Although …


Rodent Outbreaks In North America, Gary W. Witmer, Gilbert Proulx Jan 2010

Rodent Outbreaks In North America, Gary W. Witmer, Gilbert Proulx

United States Department of Agriculture Wildlife Services: Staff Publications

Fluctuations in rodent population densities in North America are a reality. Our understanding of the factors causing such fluctuations is incomplete; therefore, it is important to monitor populations to increase our understanding of natural wildlife communities so as to avoid substantial damage to agriculture, forestry, and urban infrastructures, and to prevent rodent-borne disease transmission to humans. There is a need to establish integrated pest management programs in which monitoring, preventive cultural practices, and various control methods (mechanical, physical, biological, and chemical) are strategically coordinated to maintain rodent population densities at acceptable pest levels.


Sustained Agricitlture: The Need To Manage Rodent Damage, Gary W. Witmer, Grant R. Singleton Jan 2010

Sustained Agricitlture: The Need To Manage Rodent Damage, Gary W. Witmer, Grant R. Singleton

United States Department of Agriculture Wildlife Services: Staff Publications

The need for sustained agricultural production increases as the world's human population increases, many natural resources grow scarce, and the amount of land devoted to agriculture declines. For example, Vietnam loses 30,000 ha annually of prime lice land to urban development, yet it is the second highest exporter of rice in a world market that reached crisis levels during 2008 (Meerburg et al, 2009b), Between 1960 and 2000, the world's population doubled; in Asia alone the annual population growth until 2020 is estimated at 75 million, which is a lot of new mouths to feed (FAO, 2008). Hence, feeding …


The Ties That Bind: Soil Surveyor William Edgar Tharp And Oceanographic Cartographer Marie Tharp, Edward R. Landa Jan 2010

The Ties That Bind: Soil Surveyor William Edgar Tharp And Oceanographic Cartographer Marie Tharp, Edward R. Landa

United States Geological Survey: Staff Publications

The link between soil science and geology is personified in the American father and daughter: soil surveyor William Edgar Tharp (1870–1959) and oceanographic cartographer Marie Tharp (1920–2006). From 1904 to 1935, W.E. Tharp mapped soils in 14 states for the US Department of Agriculture, and campaigned during the late 1920s–early 1930s to raise awareness of the high rates of soil erosion from croplands. The lifestyle of the federal soil surveyor in the United States during the early 20th century involved frequent household moves, and it played a formative role in Marie Tharp’s childhood. Her path to a career in geology …


Status Of The California Condor (Gymnogyps Californianus) And Efforts To Achieve Its Recovery, Jeffrey R. Walters, Scott R. Derrickson, D. Michael Fry, Susan M. Haig, John M. Marzluff, Joseph M. Wunderle Jr. Jan 2010

Status Of The California Condor (Gymnogyps Californianus) And Efforts To Achieve Its Recovery, Jeffrey R. Walters, Scott R. Derrickson, D. Michael Fry, Susan M. Haig, John M. Marzluff, Joseph M. Wunderle Jr.

United States Geological Survey: Staff Publications

The California Condor (Gymnogyps californianus; hereafter “condor”; Fig. 1) has long been symbolic of avian conservation in the United States. Its large size, inquisitiveness, and association with remote places make it highly charismatic, and its decline to the brink of extinction aroused a continuing public interest in its plight. By 1982, only 22 individuals remained of this species whose range once encompassed much of North America. The last wild bird was trapped and brought into captivity in 1987, which rendered the species extinct in the wild (Snyder and Snyder 1989). In the 1980s, some questioned whether viable populations …


Research Methodology For Validation Of Nutrition Diagnostic Standardized Language Using Fehring Models, Paula K. Ritter-Gooder, Nancy M. Lewis Jan 2010

Research Methodology For Validation Of Nutrition Diagnostic Standardized Language Using Fehring Models, Paula K. Ritter-Gooder, Nancy M. Lewis

Department of Nutrition and Health Sciences: Faculty Publications

Validation of the nutrition standardized language (SL) confirms the language is accurate for use in practice, research, and policy. Nutrition diagnostic terms are identified by concept analysis using literature review and experts to distinguish and differentiate one nutrition problem from a similar or related problem. The Fehring models, used in nursing diagnosis validation research, are adopted to validate the SL nutrition diagnostic terms using experts and weighted inter-rater reliability ratios. In the first phase of validation research, diagnostic terms are validated by experts using the Diagnostic Content Validity Model (DCV). A Nutrition Diagnosis Validation Instrument (NDVI) is developed that contains …


Targeted Deletion Of Hepatocyte Abca1 Leads To Very Low Density Lipoprotein Triglyceride Overproduction And Low Density Lipoprotein Hypercatabolism, Soonkyu Chung, Jenelle M. Timmins, Myngan Duong, Chiara Degirolamo, Shunxing Rong, Janet K. Sawyer, Roshni R. Singaraja, Michael R. Hayden, Nobuyo Maeda, Lawrence L. Rudel, Gregory S. Shelness, John S. Parks Jan 2010

Targeted Deletion Of Hepatocyte Abca1 Leads To Very Low Density Lipoprotein Triglyceride Overproduction And Low Density Lipoprotein Hypercatabolism, Soonkyu Chung, Jenelle M. Timmins, Myngan Duong, Chiara Degirolamo, Shunxing Rong, Janet K. Sawyer, Roshni R. Singaraja, Michael R. Hayden, Nobuyo Maeda, Lawrence L. Rudel, Gregory S. Shelness, John S. Parks

Department of Nutrition and Health Sciences: Faculty Publications

Loss of ABCA1 activity in Tangier disease (TD) is associated with abnormal apoB lipoprotein (Lp) metabolism in addition to the complete absence of high density lipoprotein (HDL). We used hepatocyte-specific ABCA1 knock-out (HSKO) mice to test the hypothesis that hepatic ABCA1 plays dual roles in regulating Lp metabolism and nascent HDL formation. HSKO mice recapitulated the TD lipid phenotype with postprandial hypertriglyceridemia, markedly decreased LDL, and near absence of HDL. Triglyceride (TG) secretion was 2-fold higher in HSKO compared with wild type mice, primarily due to secretion of larger TG-enriched VLDL secondary to reduced hepatic phosphatidylinositol 3-kinase signaling. HSKO mice …


A Novel Role For Abca1-Generated Large Pre- Β Migrating Nascent Hdl In The Regulation Of Hepatic Vldl Triglyceride Secretion, Soonkyu Chung, Abraham K. Gebre, Jeongmin Seo, Gregory S. Shelness, John S. Parks Jan 2010

A Novel Role For Abca1-Generated Large Pre- Β Migrating Nascent Hdl In The Regulation Of Hepatic Vldl Triglyceride Secretion, Soonkyu Chung, Abraham K. Gebre, Jeongmin Seo, Gregory S. Shelness, John S. Parks

Department of Nutrition and Health Sciences: Faculty Publications

In Tangier disease, absence of ATP binding cassette transporter A1 (ABCA1) results in reduced plasma HDL and elevated triglyceride (TG) levels. We hypothesized that hepatocyte ABCA1 regulates VLDL TG secretion through nascent HDL production. Silencing of ABCA1 expression in oleate-stimulated rat hepatoma cells resulted in: 1) decreased large nascent HDL (>10 nm diameter) and increased small nascent HDL (<10 nm) formation, 2) increased large buoyant VLDL1 particle secretion, and 3) decreased phosphatidylinositol-3 (PI3) kinase activation. Nascent HDL-containing conditioned medium from rat hepatoma cells or HEK293 cells transfected with ABCA1 was effective in increasing PI3 kinase activation and reducing VLDL TG secretion in ABCA1-silenced hepatoma cells. Addition of isolated large nascent HDL particles to ABCA1-silenced hepatoma cells inhibited VLDL TG secretion to a greater extent than small nascent HDL. Similarly, addition of recombinant HDL, but not human plasma HDL, was effective in attenuating TG secretion and increasing PI3 kinase activation in ABCA1-silenced cells. Collectively, these data suggest that large nascent HDL particles, assembled by hepatic ABCA1, generate a PI3 kinase-mediated autocrine signal that attenuates VLDL maturation and TG secretion. This pathway may explain the elevated plasma TG concentration that occurs in most Tangier subjects and may also account, in part, for the inverse relationship between plasma HDL and TG concentrations in individuals with compromised ABCA1 function.


Niemann-Pick C1-Like 1 Deletion In Mice Prevents High-Fat Diet-Induced Fatty Liver By Reducing Lipogenesis, Lin Jia, Yinyan Ma, Shunxing Rong, Jenna L. Betters, Ping Xie, Soonkyu Chung, Nanping Wang, Weiqing Tang, Liqing Yu Jan 2010

Niemann-Pick C1-Like 1 Deletion In Mice Prevents High-Fat Diet-Induced Fatty Liver By Reducing Lipogenesis, Lin Jia, Yinyan Ma, Shunxing Rong, Jenna L. Betters, Ping Xie, Soonkyu Chung, Nanping Wang, Weiqing Tang, Liqing Yu

Department of Nutrition and Health Sciences: Faculty Publications

Niemann-Pick C1-Like 1 (NPC1L1) mediates intestinal absorption of dietary and biliary cholesterol. Ezetimibe, by inhibiting NPC1L1 function, is widely used to treat hypercholesterolemia in humans. Interestingly, ezetimibe treatment appears to attenuate hepatic steatosis in rodents and humans without a defined mechanism. Overconsumption of a high-fat diet (HFD) represents a major cause of metabolic disorders including fatty liver. To determine whether and how NPC1L1 deficiency prevents HFD-induced hepatic steatosis, in this study, we fed NPC1L1 knockout (L1-KO) mice and their wild-type (WT) controls an HFD, and found that 24 weeks of HFD feeding causes no fatty liver in L1-KO mice. Hepatic …


Nutrition-Related Practices And Attitudes Of Kansas Skipped-Generation(S) Caregivers And Their Grandchildren, Mary Meck Higgins, Bethany J. Murray Jan 2010

Nutrition-Related Practices And Attitudes Of Kansas Skipped-Generation(S) Caregivers And Their Grandchildren, Mary Meck Higgins, Bethany J. Murray

Department of Nutrition and Health Sciences: Faculty Publications

Despite growing numbers, the nutrition practices and attitudes of skipped-generation(s) kinship caregivers regarding feeding the dependent children in their care have not been examined. In this qualitative study, transcriptions of semi-structured interviews with 19 female and four male skipped-generation(s) Kansas caregivers (ages 47 to 80, 92% non-Hispanic whites, 83% female, 78% grandparents and 22% great-aunt or great-grandparent caregivers; caring for a range of one to four children, ages three to 18, for an average of nine years) were content analyzed for how their nutrition-related practices and attitudes had changed since parenting the first time. Sub-themes regarding practices included: being more …


Predicting Successful Aging In A Population-Based Sample Of Georgia Centenarians, Jonathan Arnold, Jianliang Dai, Lusine Nahapetyan, Ankit Arte, Mary Ann Johnson, Dorothy Hausman, Willard L. Rodgers, Robert Hensley, Peter Martin, Maurice Macdonald, Adam Davey, Ilene C. Siegler, S. Michal Jazwinski, Leonard W. Poon Jan 2010

Predicting Successful Aging In A Population-Based Sample Of Georgia Centenarians, Jonathan Arnold, Jianliang Dai, Lusine Nahapetyan, Ankit Arte, Mary Ann Johnson, Dorothy Hausman, Willard L. Rodgers, Robert Hensley, Peter Martin, Maurice Macdonald, Adam Davey, Ilene C. Siegler, S. Michal Jazwinski, Leonard W. Poon

Department of Nutrition and Health Sciences: Faculty Publications

Used a population-based sample (Georgia Centenarian Study, GCS), to determine proportions of centenarians reaching 100 years as (1) survivors (43%) of chronic diseases first experienced between 0–80 years of age, (2) delayers (36%) with chronic diseases first experienced between 80–98 years of age, or (3) escapers (17%) with chronic diseases only at 98 years of age or older. Diseases fall into two morbidity profiles of 11 chronic diseases; one including cardiovascular disease, cancer, anemia, and osteoporosis, and another including dementia. Centenarians at risk for cancer in their lifetime tended to be escapers (73%), while those at risk for cardiovascular disease …


How Specialists Can Be Generalists: Resolving The "Parasite Paradox" And Implications For Emerging Infectious Disease, Salvatore J. Agosta, Niklas Janz, Daniel R. Brooks Jan 2010

How Specialists Can Be Generalists: Resolving The "Parasite Paradox" And Implications For Emerging Infectious Disease, Salvatore J. Agosta, Niklas Janz, Daniel R. Brooks

Harold W. Manter Laboratory of Parasitology: Faculty Publications

The parasite paradox arises from the dual observations that parasites (broadly construed, including phytophagous insects) are resource specialists with restricted host ranges, and yet shifts onto relatively unrelated hosts are common in the phylogenetic diversification of parasite lineages and directly observable in ecological time. We synthesize the emerging solution to this paradox: phenotypic flexibility and phylogenetic conservatism in traits related to resource use, grouped under the term ecological fitting, provide substantial opportunities for rapid host switching in changing environments, in the absence of the evolution of novel host-utilization capabilities. We discuss mechanisms behind ecological fitting, its implications for defining specialists …


First Report Of Viral Pathogens Wssv And Ihhnv In Argentine Crustaceans [Note], Sergio Roberto Martorelli, Robin M. Overstreet, Jean A. Jovanovich Alvillar Jan 2010

First Report Of Viral Pathogens Wssv And Ihhnv In Argentine Crustaceans [Note], Sergio Roberto Martorelli, Robin M. Overstreet, Jean A. Jovanovich Alvillar

Harold W. Manter Laboratory of Parasitology: Faculty Publications

The pathogenic penaeid shrimp viruses white spot syndrome virus (WSSV) and infectious hypodermal and hematopoietic necrosis virus (IHHNV) are reported for the first time from Argentina. They both occurred in wild crustaceans in Bahia Blanca Estuary, with WSSV detected by polymerase chain reaction (pCR) or real time quantitative pCR (qpCR) methods as infecting samples as high as 56% of the penaeid Artemesia longinaris Bate, 1888, 67% of the grapsoid Cyrtograpsus angulatus dana, 1851, and 40% of the introduced palaemonid Palaemon macrodactylus Rathbun, 1902. The highest detected copy number was 39,600 copies/μg dNA. IHHNV was tested for using pCR in …


Barcoding Bushmeat: Molecular Identification Of Central African And South American Harvested Vertebrates, Mitchell J. Eaton, Greta J. Meyers, Sergios-Orestis Kolokotronis, Matthew S. Leslie, Andrew P. Martin, George Amato Jan 2010

Barcoding Bushmeat: Molecular Identification Of Central African And South American Harvested Vertebrates, Mitchell J. Eaton, Greta J. Meyers, Sergios-Orestis Kolokotronis, Matthew S. Leslie, Andrew P. Martin, George Amato

United States Geological Survey: Staff Publications

The creation and use of a globally available database of DNA sequences from a standardized gene region has been proposed as a tool for species identification, assessing genetic diversity and monitoring the legal and illegal trade in wildlife species. Here, we contribute to the Barcode of Life Data System and test whether a short region of the mitochondrial cytochrome c oxidase subunit 1 (COX1) gene would reliably distinguish among a suite of commonly hunted African and South American mammal and reptile species. We used universal primers to generate reference barcode sequences of 645 bp for 23 species from five vertebrate …


Barcoding Bushmeat: Molecular Identification Of Central African And South American Harvested Vertebrates, Mitchell J. Eaton, Greta L. Meyers, Sergios-Orestis Kolokotronis, Matthew S. Leslie, Andrew P. Martin, George Amato Jan 2010

Barcoding Bushmeat: Molecular Identification Of Central African And South American Harvested Vertebrates, Mitchell J. Eaton, Greta L. Meyers, Sergios-Orestis Kolokotronis, Matthew S. Leslie, Andrew P. Martin, George Amato

United States Geological Survey: Staff Publications

The creation and use of a globally available database of DNA sequences from a standardized gene region has been proposed as a tool for species identification, assessing genetic diversity and monitoring the legal and illegal trade in wildlife species. Here, we contribute to the Barcode of Life Data System and test whether a short region of the mitochondrial cytochrome c oxidase subunit 1 (COX1) gene would reliably distinguish among a suite of commonly hunted African and South American mammal and reptile species. We used universal primers to generate reference barcode sequences of 645 bp for 23 species from five vertebrate …


Why "Democracy" And "Drifter" Firms Can Have Abnormal Returns: The Joint Importance Of Corporate Governance And Abnormal Accruals In Separating Winners From Losers, Koon Boon Kee Jan 2010

Why "Democracy" And "Drifter" Firms Can Have Abnormal Returns: The Joint Importance Of Corporate Governance And Abnormal Accruals In Separating Winners From Losers, Koon Boon Kee

Dissertations and Theses Collection (Open Access)

Do managers exercise accounting discretion in an opportunistic or efficient manner? Good governance structures, which mitigate agency costs, are necessary to ensure that the accounting information supplied by management is not opportunistically manipulated. The output of quality accounting information, in turn, serves as an input to better governance structures. Thus, governance and earnings quality (EQ) are inexorably linked through a complementarity relationship. This suggests two previously unexamined relationships. Firstly, the governance effects on performance in the influential paper by Gompers, Ishii and Metrick (2003) is overrated without good EQ, measured by the magnitude of abnormal accruals (AA), as an input. …


Does Corporate Governance Matter, Evidence From Earnings Management Practices In Singapore, Lingxu Hu Jan 2010

Does Corporate Governance Matter, Evidence From Earnings Management Practices In Singapore, Lingxu Hu

Dissertations and Theses Collection (Open Access)

This paper addresses two questions. First, do good corporate governance practices add values to company or does it lead to higher stock returns in Singapore? Second, does poorly governed listed company in SGX tend to manage their earnings by using discretionary accruals? Following the approach of Gompers et al. (2003), we formed two portfolios consisting of well-governed and poorly governed companies. Well governed companies are able to maintain a higher return relative to poorly governed companies. I also look at the firm valuation from the adoption of corporate governance practices. Our result shows a positive relationship between firm valuation and …


Risk Response Strategies In The Supply Chain: Examining Attributes Of Stakeholders And Risk Attitude, Shu Jian Lim Jan 2010

Risk Response Strategies In The Supply Chain: Examining Attributes Of Stakeholders And Risk Attitude, Shu Jian Lim

Dissertations and Theses Collection (Open Access)

Supply chain management is about managing flows of material, information and funds in a complex network of entities of suppliers, manufacturers, distributors and customers. Companies are now connected in this network as an extended enterprise and any company may be involved in more than one such extended enterprises. But, such a network of relationships is very much vulnerable to disruptions of all sorts ranging from internal to inter-firm and to external turbulences. Companies now need to be prepared for risks associated with their participation in the supply chain network. Not many works in the literature have used theories to study …


Bone Marrow Examination Findings At Aga Khan University Hospital, Nairobi, Nancy Okinda, Riyat Malkit Jan 2010

Bone Marrow Examination Findings At Aga Khan University Hospital, Nairobi, Nancy Okinda, Riyat Malkit

Pathology, East Africa

Objective: To establish the bone marrow examination findings and determine the indication for bone marrow examination.

Design: A retrospective audit.

Setting: Aga Khan University Hospital, Nairobi.

Subjects: All bone marrow aspirates done at Aga Khan University for the period comprising February 2003 to February 2006 were retrieved and analysed.

Results: A total of 356 patient’s case histories including bone marrow examination results were analysed. Ages of the patients ranged from 18 months to 91 years. Males were 180 (50.6%) and females were 176 (49.4%). Nutritional anaemia as a group was the most common haematological disorder found on bone marrow …


Who Gets Prompt Access To Artemisinin-Based Combination Therapy? A Prospective Community-Based Study In Children From Rural Kilosa, Tanzania, D.O. Simba, M. Warsame, D. Kakoko, Z. Mrango, G. Tomson, Zul Premji, M. Petzold Jan 2010

Who Gets Prompt Access To Artemisinin-Based Combination Therapy? A Prospective Community-Based Study In Children From Rural Kilosa, Tanzania, D.O. Simba, M. Warsame, D. Kakoko, Z. Mrango, G. Tomson, Zul Premji, M. Petzold

Pathology, East Africa

Background: Effective and timely case management remains one of the fundamental pillars for control of malaria. Tanzania introduced artemisinin-combination therapy [ACT] for uncomplicated malaria; however, the policy change is challenged by limited availability of ACTs due to high cost. This study aimed to determine factors influencing prompt access to ACTs among febrile children in rural Kilosa, Tanzania.

Methods and Findings: In a community-based study, 1,235 randomly selected children under five were followed up weekly for six months, in 2008. Using a structured questionnaire, children's caretakers were asked about the child's febrile history in the last seven days, and treatment …


Understanding Caretakers' Dilemma In Deciding Whether Or Not To Adhere With Referral Advice After Pre-Referral Treatment With Rectal Artesunate, D.O. Simba, D.C. Kakoko, M. Warsame, Zul Premji, M.F. Gomes, G. Tomson, E. Johansson Jan 2010

Understanding Caretakers' Dilemma In Deciding Whether Or Not To Adhere With Referral Advice After Pre-Referral Treatment With Rectal Artesunate, D.O. Simba, D.C. Kakoko, M. Warsame, Zul Premji, M.F. Gomes, G. Tomson, E. Johansson

Pathology, East Africa

Background: Malaria kills. A single rectal dose of artesunate before referral can reduce mortality and prevent permanent disability. However, the success of this intervention depends on caretakers' adherence to referral advice for follow-up care. This paper explores the dilemma facing caretakers when they are in the process of deciding whether or not to transit their child to a health facility after pre-referral treatment with rectal artesunate.

Methods: Four focus group discussions were held in each of three purposively selected villages in Mtwara rural district of Tanzania. Data were analysed manually using latent qualitative content analysis.

Results: The theme «Caretakers dilemma …


Population Genetic Analysis Of Large Sequence Polymorphisms In Plasmodium Falciparum Blood-Stage Antigens, A.D. Ahouidi, A.K. Bei, D.E. Neafsey, O. Sarr, S. Volkman, D. Milner, J. Cox-Singh, M.U. Ferreira, O. Ndir, Zul Premji, S. Mboup, M.T. Duraisingh Jan 2010

Population Genetic Analysis Of Large Sequence Polymorphisms In Plasmodium Falciparum Blood-Stage Antigens, A.D. Ahouidi, A.K. Bei, D.E. Neafsey, O. Sarr, S. Volkman, D. Milner, J. Cox-Singh, M.U. Ferreira, O. Ndir, Zul Premji, S. Mboup, M.T. Duraisingh

Pathology, East Africa

Plasmodium falciparum, the causative agent of human malaria, invades host erythrocytes using several proteins on the surface of the invasive merozoite, which have been proposed as potential vaccine candidates. Members of the multi-gene PfRh family are surface antigens that have been shown to play a central role in directing merozoites to alternative erythrocyte receptors for invasion. Recently, we identified a large structural polymorphism, a 0.58 Kb deletion, in the C-terminal region of the PfRh2b gene, present at a high frequency in parasite populations from Senegal. We hypothesize that this region is a target of humoral immunity. Here, by analyzing 371 …


When The Supreme Court Came To Michigan, Leonard M. Niehoff Jan 2010

When The Supreme Court Came To Michigan, Leonard M. Niehoff

Articles

It is an arcane and curious chapter in the history of the federal courts. Under the terms of the Judiciary Act of 1789, the members of the Supreme Court of the United States were obligated to travel around the country and hear cases that were brought before the lower courts in their assigned circuits. This resulted in what the justices condemned as a "painful and improper situation. "


Law And The Social Control Of American Capitalism, William J. Novak Jan 2010

Law And The Social Control Of American Capitalism, William J. Novak

Articles

This Essay is part of a larger, ongoing investigation of the role of law in the creation of a modern American state from 1877 to 1932. That project charts the decline of an early nineteenth-century world of local, common law self government (what I called in a previous work a “well-regulated society”) and the rise of a distinctly modern administrative regulatory state in the United States. This new legal-political regime was rooted in three interlinked developments: the centralization of public power; the individualization of private right; and the constitutionalization of the rule of law. Beginning soon after the Civil War, …