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Energy Reduction In Automotive Paint Shops A Review Of Hybrid/Electric Vehicle Battery Manufacturing, Claudia Patricia Arenas Guerrero

University of Kentucky Master's Theses

Automotive industry is facing fundamental challenges due to the rapid depletion of fossil fuels, energy saving and environmental concerns. The need of sustainable energy development has motivated the research of energy reduction and renewable energy sources. Efficient use of energy in vehicle manufacturing is demanded, as well as an alternative energy source to replace gasoline powered engines. In this thesis, we introduce a case study at an automotive paint shop, where the largest amount of energy consumption of an automotive assembly plant takes place. Additionally, we present a summary of recent advances in the area of hybrid and electrical vehicles …

The Role Of Corporate Law In Preventing A Financial Crisis: Reflections On In Re Citigroup Inc. Shareholder Derivative Litigation, Franklin A. Gevurtz

McGeorge School of Law Scholarly Articles

No abstract provided.

What The Abortion Disclosure Cases Say About The Constitutionality Of Persuasive Government Speech On Product Labels, Leslie Gielow Jacobs

McGeorge School of Law Scholarly Articles

No abstract provided.

Beyond International Water Law: Successfully Negotiating Mutual Gains Agreements For International Watercourses, Alex Grzybowski, Stephen C. Mccaffrey, Richard K. Paisley

McGeorge School of Law Scholarly Articles

No abstract provided.

Staying The Course: U.S. Employment Strategy During The Great Recession, Randall W. Eberts

Periodical Articles

No abstract provided.

Rehabilitating Mental Disorder Evidence After Clark C. Arizona: Of Burdens, Presumptions, And The Rights To Raise Reasonable Doubt, Dora W. Klein

Faculty Articles

The right not to be found guilty of a crime absent proof beyond a reasonable doubt is a powerful right. It can be undermined, however, by rules that at first seem to have little to do with reasonable doubt or with burdens of proof.

In the recent case of Clark v. Arizona, the Supreme Court considered whether states may enact rules that categorically prohibit criminal defendants from offering mental disorder evidence for the purpose of raising reasonable doubt regarding the mens rea element of a charged offense. In Arizona law, mental disorder evidence is inadmissible for the purpose of disproving …

Sources Of Entrepreneurial Discretion In Kinship Systems, Alex Stewart

Management Faculty Research and Publications

Entrepreneurs may wish to be selective about which relatives to include or exclude in their businesses. For example, their child might be inept but their niece might be outstanding. What aspects of kinship systems affect their ability to make these sorts of choices? What enables them to bend their ties of kinship and marriage to the interests of their business? Most broadly, what dimensions of kinship lend themselves to tactical or instrumental actions? This question is sweeping just as my meaning of “entrepreneurs” is very broad: those who take actions with the goal of growing their capital (Stewart, 1991). This …

Irrelevent Confusion, Mark P. Mckenna, Mark A. Lemley

Journal Articles

Trademark law centers its analysis on consumer confusion. With some significant exceptions, the basic rule of trademark law is that a defendant’s use of a mark is illegal if it confuses a substantial number of consumers and not otherwise.

As a general matter, this is the right rule. Trademark law is designed to facilitate the workings of modern markets by permitting producers to accurately communicate information about the quality of their products to buyers, and therefore to encourage them to invest in making quality products in circumstances in which that quality wouldn’t otherwise be apparent. If competitors can falsely mimic …

Affordable Private Education And The Middle Class City, Nicole Stelle Garnett

Journal Articles

This Essay, which was prepared for a University of Chicago Law School’s symposium on “Rethinking the Local Government Toolkit,” argues that affordable private schools serve an important urban-development function: They partially unbundle the residential and educational decisions of families with children. Thus, state and local officials hoping to make our make central city neighborhoods attractive places to raise children should consider employing a familiar urban development tool - tax incentives - to make quality private schools more financially accessible to middle-income families. The Essay proceeds in three parts. Part I builds the case for a middle class city. Part II …

Forgiveness Education: Urban Youth's Perceptions And Collective Narratives, Sharon Chubbuck

College of Education Faculty Research and Publications

No abstract provided.

Dimethylmercury Production In Freshwater Sediments, David C. Kelly

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Dimethylmercury (DMHg) has been examined almost exclusively in marine environments to date, plays an uncertain role in the global cycling of Hg, and is produced by a currently unknown mechanism in natural systems. We examined DMHg production in microcosms containing 100 cm3 of freshwater sediment sampled from 3 wetlands and a lake near Dayton, Ohio. DMHg was produced from all sediments analyzed, and found that production is increased significantly by the addition of inorganic Hg from ~0.1pM to ~10pM, its production is unaffected by autoclaving the sediment, and organic carbon additions had no discernible effect on production. Its total concentrations …

In-Vitro Metabolism And Protein Binding Of 5-Hmf, A Potential Antisickling Agent, Taghrid Obied

Theses and Dissertations

Purpose. 5-HMF is a potential antisickling agent forming a Schiff-adduct with hemoglobin (Hb). In-vitro studies were designed to identify the metabolic pathways of 5-HMF in human hepatic cytosol, to assess inter-species differences in its hepatic metabolism, and to predict in-vivo PK properties. Moreover, metabolism of 5-HMF in human RBCs was investigated. Finally, in-vitro studies were done to characterize 5-HMF binding kinetics with human Hb and albumin (HSA). Methods. NAD+ reduction was monitored at 340 nm in human hepatic cytosol for 5-HMF (26 mM) and prototypical ADH and ALDH substrates in the presence or absence of their inhibitors. Furthermore, concentration-dependency studies …

The Im-9 Cell Line: A Model For Evaluating Tcdd-Induced Modulation Of The Polymorphic Human Hs1,2 Enhancer Within The 3' Immunoglobulin Heavy Chain Regulatory Region, Ruth C. Chambers-Turner

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2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), a disrupter, of B-cell differentiation, induces binding of the aryl hydrocarbon receptor (AhR) nuclear complex to dioxin responsive elements (DRE) within the mouse immunoglobulin heavy chain regulatory region (3'IgHRR), and produces a marked inhibition of 3'IgHRR activation, IgH expression, and antibody secretion in a well-characterized mouse B-cell line (CH12.LX). The mouse 3'IgHRR consists of at least four enhancers (hs3a; hs1,2; hs3b; hs4), and is highly homologous with the three enhancers (hs3; hs1,2; hs4) of the human 3'IgHRR. A polymorphism of the human hs1,2 enhancer (resulting in varying numbers of tandem repeats containing a DRE and κB site) has …

The Role Of Apoptosis In Hela Cells Expressing Hiv-1 Rev, Elizabeth Page

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The HIV protein Rev is a nucleolar protein that regulates late gene expression in infected cells by promoting the export of under-spliced viral RNAs (Pollard and Malim, 1998). Its over-expression can also inhibit progression through mitosis (Miyazaki et al., 1995), possibly through its ability to depolymerize microtubules (Watts et al., 2000). Consequently, Rev may activate the spindle assembly checkpoint in mitotic cells and increase the frequency of apoptosis. Rev also binds the nucleolar protein B23 involved in ribosome maturation and centrosome duplication. Because loss of B23 function stimulates apoptosis (Ahn et al., 2005), Rev expression may promote apoptosis by inhibiting …

Short-Term Administration Of Corticosterone Has Lasting Effects On Learning In Young Rats, Christine L. Wentworth-Eidsaune

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Corticosterone is a glucocorticoid released as part of the body's response to stress and is known to affect cognitive function, presumably via effects on the hippocampus. Trace classical eyeblink conditioning depends on the hippocampus, and has been used to examine the development of learning processes in young organisms. Experiment 1 was a dosing study, in which time course of effect of corticosterone was followed in 15-day-old Long-Evans rat pups over 24 hours for 4 different concentrations (high: 0.02 mg/g body weight (b.w.), medium: 0.01mg/g b.w., low: 0.005 mg/g b.w. and a vehicle control). In Experiment 2, two subcutaneous injections (0.02 …

Millennial Students Who Go Directly To Graduate School: Influences On This Decision And The Characterization Of Their Experience, Courtney A. Smith

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The purpose of this research study was to explore the issues surrounding Millennial students who go directly into graduate school after completing an undergraduate degree including what influenced this decision and how the students characterized the experience. Participants were interviewed and several themes emerged from this study: feeling not ready for the real world or qualified to work, differences and difficulties of graduate life compared to undergraduate life, more academic support is needed before and during graduate school, relationships with parents were evolving towards independence, the importance of grades, lack of campus involvement in graduate school, overcoming personal and academic …

Developmental Expression Of Calcium Buffering Proteins In Central Auditory Pathways Of Normal Hearing And Congenitally Deaf Mice, Adam S. Deardorff

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These experiments analyze differences in synaptic development in central auditory pathways between normal hearing (CBA/J) and congenitally deaf (dn/dn) mice, which provide valuable insight into central synaptic plasticity corresponding to human congenital deafness. Immunofluorescent analysis of the developmental expression of the calcium buffering proteins calretinin, calbindin d-28k, and parvalbumin at various postnatal time points was performed to assess the effects of altered neural activity on the level and/or pattern of protein expression within these nuclei. Results indicate that the pattern of calbindin and parvalbumin is unaffected by congenital deafness in dn/dn mice. However, the pattern of calretinin expression in the …

Quantitative Structure-Activity Relationships For Organophosphates Binding To Trypsin And Chymotrypsin, Christopher Daniel Ruark

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Organophosphate (OP) nerve agents such as sarin, soman, tabun, and O-ethyl S-[2-(diisopropylamino) ethyl] methylphosphonothioate (VX) do not react solely with acetylcholinesterase (AChE). Evidence suggests that a wide range of cholinergic-independent pathways are also targeted, including serine proteases. These proteases comprise nearly one-third of all known proteases and play major roles in synaptic plasticity, learning, memory, neuroprotection, wound healing, cell signaling, inflammation, blood coagulation and protein processing. Inhibition of these proteases by OPs was found to exert a wide range of noncholinergic effects depending on the type of OP, the dose, and the duration of exposure. Consequently, in order to understand …

Surveillance In A Smart Home Environment, Ryan Stewart Patrick

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A system for assisting the elderly in maintaining independent living is currently being designed. When mature, it is expected that this system will have the ability to track objects that a resident may lose periodically, detect falls within the home, and alert family members or health care professionals to abnormal behaviors.

This thesis addresses the early stages of this system's development. It presents a survey of the work that has previously been completed in the area of surveillance within a home environment, information on the physical characteristics of the system that is being designed, early results related to this system, …

P63 And Vdr Are Regulated By Vitamin D (Vd3) And Uv Signaling, Andrew J. Whitlatch

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Skin cancers, such as squamous cell carcinoma (SCC), develop from accumulated mutations as a result of excessive exposure to Ultraviolet B (UVB) radiation. Intriguingly, UVB also catalyzes the synthesis of 1alpha, 25-dihydroxy Vitamin D3 (VD3), the hormonally active form of Vitamin D. Downstream VD3 signaling has been associated with promoting the inhibition of cell cycle progression, regulating calcium homeostasis, and inducing differentiation and apoptosis. VD3 mediates these processes via genomic mechanisms through interaction with its cognate receptor, the Vitamin D Receptor, (VDR). In addition, it was recently discovered that VD3 reduces UVB-mediated phosphorylation of the SAPK/c-Jun N-terminal kinase (JNK), which …

Functional Identification Of Microorganisms That Transform Mercury In Marine Sediments, Lisa Romas

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Monomethylmercury (MMHg) is the toxic form of mercury (Hg) that biomagnifies in food webs, and human exposure to MMHg occurs predominantly via consumption of fish. The primary source of MMHg to the marine environment is thought to be in situ sedimentary production by benthic microorganisms, namely sulfate-reducing bacteria (SRB). I collected sediments from the continental shelf (stations 2 and 6) and slope (station 9) of the NW Atlantic Ocean, and amended them with various inhibitor and promoter solutions to target specific functional groups capable of Hg transformations. I also added stable enriched Hg isotopes to quantify gross Hg methylation and …

Hyperbaric Oxygen In The Prevention Of Carbon Monoxide Induced Delayed Neurological Sequelae In Male Sprague Dawley Rats (Rattus Norvegicus), Chester P. Gut Jr.

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In Carbon Monoxide (CO) induced Delayed Neurological Sequelae (DNS) clinical signs develop 1 to 6 weeks after CO has cleared the body. The aim of this experiment was to develop a model of CO induced DNS which closely mimics "real world" conditions both in exposure and treatment. The model was challenged with hyperbaric or normobaric oxygen, or room air. Basic behaviors were measured by Open Field test on days 1, 7, 14 post exposure and treatment. No significant difference in behavior was observed between exposed and control animals or between treatment groups. Histological analyses showed no DNA or necrotic damage …

Dammed And The Damned: Draining The Bucket Dry, Carla Steiger

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This thesis investigates how people displaced from the construction of large dams in seek environmental justice. I studied the importance of regime type, the creation of protest groups and the formation of alliances with national, international organizations, and the media. In a comparison between protest movements against the Three Gorges Dam in China and the Sardar Sarovar Dam in India, displaced populations suffered from loss of community, livelihood, and health and were victimized by corrupt actors that supported the dams. The rapid economic development of these two countries emerged as a major point of comparison between the two. Regime type …

A Comparison Of Atmospheric Pahs In Pine Needles And High-Volume Sampler Filters In The Dayton Metro Area, Timothy A. Tomashuk

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Samples of filters from High-volume (HiVol) samplers of particulate matter (PM) with a size of 10 micrometers or less were deployed for five months in Moraine and Yellow Springs, OH, by the Regional Air Protection Control Agency and analyzed for the Environmental Pollution Agency (EPA) 16 polycyclic aromatic hydrocarbons (PAHs). Pine needles on trees near the HiVol samplers were also collected and analyzed for a comparison with the active samplers to estimate atmospheric PAH concentrations. Pine needles were found to collect lower molecular weight (LMW) compounds far more than HiVol sampler and thus their profiles shown to compliment the HiVol …

Wideband, High Data Rate Ku-Band Modulator Driver Amplifier For High Reliability Spaceborne Applications, Jeremy D. Gassmann

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The increased demand for high resolution satellite imagery for government, military, and commercial applications is driving the need for high data rate, millimeter-wave transmission systems to relay imagery information to a ground-based end user. An important aspect of this system which interfaces digital information to the RF domain is the modulator driver. The current trend in miniaturization of electronics leaves systems more vulnerable to single-event radiation effects in spaceborne applications. In an effort to overcome this deficiency, a wideband, high data rate modulator driver circuit has been designed, built, and tested using only high reliability space rated electronic components. To …

Social Context For Religious Violence In The French Massacres Of 1572, Shannon L. Speight

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The project looks at violence as a social norm during the French massacres of 1572, causing widespread violence at a popular level, at the heart of which was religious group identity. The work examines outbreaks of fighting between Catholics and Huguenots starting in Paris with the St. Bartholomew's Day Massacre and spreading to provincial cities in the following months. Rather than viewing hostility as instigated from the top levels of society, this works aims to verify that there existed within France an acceptance of aggression that, encouraged by inflammatory religious rhetoric, resulted in the popular violence of the massacres. The …

Mercury Speciation In Temperate Tree Foliage, Melissa Danielle Tabatchnick

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Cycling of mercury (Hg) and monomethylmercury (MMHg) in forest ecosystems can affect exposures of terrestrial and aquatic wildlife within the watershed. Litterfall has been posited to be a major source of MMHg and total Hg to the forest floor; however, the origin of MMHg associated with tree foliage is largely unknown. I tested the hypothesis that leaf MMHg would be controlled by root uptake and thereby proportional to levels in soil. Fresh leaves and associated soil samples were sampled from nine tree species (deciduous and coniferous) at 30 locations spanning a 1145 km2 area in southwest Ohio, a region presumed …

Impact Of Culture And Age On The Use Of Social Networking Websites, Ramya Reddy Ponnavolu

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Social networking websites have become very popular amongst people of all ages in recent times. These websites have brought into existence a new form of data - 'User generated content'. Companies everywhere have begun to identify the potential of these sites and have commenced efforts to take advantage of the profitable opportunities available. In spite of all this, it is reasonable to say that the latent possibilities in social networking sites are yet to be fully explored. This is due to the fact that the technology is still young and research on its potential is still ongoing. The current research …

Trace Metal Fluxes In Southwest Ohio Watersheds, Avani Naik

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Land-use and watershed characteristics affect the cycling and transport of trace metals in rivers. I investigated the influence of different land uses and water physicochemistry on loadings, partitioning, and speciation of Hg, Zn, Cr, Ni, V, Cd, Cu, and Pb in three contrasting watersheds near the Dayton, Ohio metropolitan area over a 13-month period; Wolf Creek (urban/residential), Holes Creek (urban/residential), and Little Miami River (agricultural). Metal concentrations were related positively to discharge in each stream. Dissolved organic ligands appear to influence trace-metal partitioning between filtered and particle phases, however, particle-associated metals were dominant in each site. Total Hg concentrations and …

Prognosis: A Wearable System For Health Monitoring Of People At Risk, Alexandros A. Pantelopoulos

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Wearable Health Monitoring Systems (WHMS) have drawn a lot of attention from the research community and the industry during the last decade. The development of such systems has been motivated mainly by increasing healthcare costs and by the fact that the world population is ageing. In addition to that, RandD in WHMS has been propelled by recent technological advances in miniature bio-sensing devices, smart textiles, microelectronics and wireless communications techniques. These portable health systems can comprise various types of small physiological sensors, which enable continuous monitoring of a variety of human vital signs and other physiological parameters such as heart …