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2010

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How Do You Make Information Security User Friendly?, Andrew Jones Jan 2010

How Do You Make Information Security User Friendly?, Andrew Jones

Research outputs pre 2011

This article explores the past and the present situation, outlines a new approach, and presents conclusions.

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Digital Forensics And The Issues Of Identity, Andrew Jones, Thomas Martin Jan 2010

Digital Forensics And The Issues Of Identity, Andrew Jones, Thomas Martin

Research outputs pre 2011

The issue of what we consider to be the identity of a person has become increasingly complex as we have made ever greater use of the facilities and services that have been made available by developing technologies and the Internet. In the past people normally had one identity, while in the current environment it is acceptable to maintain separate ‘identities’ for different aspects of our on-line interactions. Proving beyond a reasonable doubt that an individual that is suspected of a crime that is based on the technologies that we increasingly rely on was the actual perpetrator has always been problematic. …

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Design Of Functionally Graded Carbon Coatings Against Contact Damage, Rajnish K. Singh, Zhifeng Zhou, Lawrence Kwok Yan Li, Paul Munroe, Mark Hoffman, Zonghan Xie Jan 2010

Design Of Functionally Graded Carbon Coatings Against Contact Damage, Rajnish K. Singh, Zhifeng Zhou, Lawrence Kwok Yan Li, Paul Munroe, Mark Hoffman, Zonghan Xie

Research outputs pre 2011

Three different functionally graded amorphous carbon (a-C) thin films were deposited on to aluminium substrates using a closed-field unbalanced magnetron sputtering ion plating method. The closed-field configuration prohibits the loss of secondary electrons and consequently enhances the plasma density significantly. The functional gradient of the a-C films was achieved by varying the bias voltage linearly during deposition. Three graded a-C systems possessing different variations in Young's modulus were deposited with the highest Young's modulus at the (i) top surface, (ii) interface or (iii) middle of the film. Of the three systems investigated, the one with the highest Young's modulus at …

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The Impact Of Consanguinity On Neonatal And Infant Health, Alan H. Bittles, Michael L. Black Jan 2010

The Impact Of Consanguinity On Neonatal And Infant Health, Alan H. Bittles, Michael L. Black

Research outputs pre 2011

Marriage between biological relatives is widely popular in many parts of the world, with over 1000 million people living in countries where 20–50+% of unions are contracted between couples related as second cousins or closer. Consanguinity is, however, a controversial topic, in part due to public misunderstanding, complicated by often exaggerated past estimates of the adverse health outcomes. While some consanguineous couples are at high risk of conceiving a child with a genetic disorder, they are a small minority. Thus a multi-population meta-analysis has indicated an excess infant death rate of 1.1% in the progeny of first cousins, and even …

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Differences In Satiety Effects Of Alginate- And Whey Protein-Based Foods, Vicky A. Solah, Deborah A. Kerr, Cynthia D. Adikara, Xingqiong Meng, Colin W. Binns, Kun Zhu, Amanda Devine, Richard L. Prince Jan 2010

Differences In Satiety Effects Of Alginate- And Whey Protein-Based Foods, Vicky A. Solah, Deborah A. Kerr, Cynthia D. Adikara, Xingqiong Meng, Colin W. Binns, Kun Zhu, Amanda Devine, Richard L. Prince

Research outputs pre 2011

Satiety is important in regulating food intake and has important public health significance in the control of obesity. Food containing protein and non-starch polysaccharides provides a satiety effect through various mechanisms but a comparison of the satiety effect on each has not previously been investigated. This study compared the satiety effect or reduction of hunger after consumption of (i) a whey proteinbased drink versus an alginate-based drink of the same viscosity where only the protein content differed, (ii) two alginate-based drinks differing in alginate type and viscosity, and (iii) a whey protein-based drink versus an alginate-based drink differing in protein …

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Lactate Dyscrasia: A Novel Explanation For Amyotrophic Lateral Sclerosis, Sivan Vadakkadath Meethal, Craig Atwood Jan 2010

Lactate Dyscrasia: A Novel Explanation For Amyotrophic Lateral Sclerosis, Sivan Vadakkadath Meethal, Craig Atwood

Research outputs pre 2011

Amyotrophic lateral sclerosis (ALS; Lou Gehrig’s disease) is a progressive debilitating neurodegenerative disease with no cure. We propose a novel molecular model for the pathogenesis of ALS that involves an adenosine triphosphate (ATP)-dependent muscle neuronal lactate shuttle (MNLS) at the neuromuscular junction (NMJ) to regulate the flow of lactate from muscle to neurons and vice versa. Failure of the MNLS due to respiratory chain dysfunction is proposed to result in lactate toxicity and degeneration of nerve endings at the NMJ leading to nerve terminus dysjunction from the muscle cell. At a critical threshold where denervation outpaces reinnervation, a vicious cycle …

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Assemblage Turnover And Taxonomic Sufficiency Of Subtidal Macroalgae At Multiplespatial Scales, Dan A. Smale, Gary A. Kendrick, Thomas Wernberg Jan 2010

Assemblage Turnover And Taxonomic Sufficiency Of Subtidal Macroalgae At Multiplespatial Scales, Dan A. Smale, Gary A. Kendrick, Thomas Wernberg

Research outputs pre 2011

Spatial variability in the structure of subtidal macroalgal assemblages in southwest Australia was examined at multiple spatial scales using a three-factor hierarchal design. Spatial extents ranged from metres (between quadrats) to many hundreds of kilometres (between regions), and the study encompassed N2000 km of temperate coastline. In addition, the influence of taxonomic resolution, from species level data to class level, on spatial patterns was investigated to assess the potential evolutionary timescales of the pattern and for developing cost effective regionally applicable surrogates for biodiversity monitoring. Almost 300 species were identified from 14 sites, representing considerable biodiversity and a significant subset …

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A Leadership Program In An Undergraduate Nursing Course In Western Australia: Building Leaders In Our Midst, Joyce M. Hendricks, Vicki C. Cope, Maureen Harris Jan 2010

A Leadership Program In An Undergraduate Nursing Course In Western Australia: Building Leaders In Our Midst, Joyce M. Hendricks, Vicki C. Cope, Maureen Harris

Research outputs pre 2011

This paper discusses a leadership program implemented in the School of Nursing at Edith Cowan University to develop leadership in fourth semester nursing students enrolled in a three year undergraduate nursing degree to prepare them for the dynamic ‘changing world’ environment of healthcare. Students were invited to apply to undertake the program in extracurricular time. Nineteen students applied to the program and ten were chosen to participate in the program. The numbers were limited to ten to equal selected industry leader mentors. The leadership program is based on the belief that leadership is a function of knowing oneself, having a …

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Adult Outcomes Of Pediatric Traumatic Brain Injury, Miriam Beauchamp, Julian Dooley, Vicki Anderson Jan 2010

Adult Outcomes Of Pediatric Traumatic Brain Injury, Miriam Beauchamp, Julian Dooley, Vicki Anderson

Research outputs pre 2011

Traumatic brain injury (TBI) is one of the most common causes of acquired disability during childhood. While the majority of such injuries are mild, and result in few, if any, functional sequelae, children sustaining more significant insults may experience permanent cognitive and behavioral deficits. Clinical reports indicate residual impairments in a range of skills, particularly information-processing, attention, memory, learning, social function and behavior. These deficits impact on a child's capacity to interact with the environment effectively, resulting in lags in skill acquisition, and increasing gaps between injured children and their age peers, as they move through childhood and into adulthood. …

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Funding And Secondary School Choice In Australia: A Historical Consideration, Rosemary Cahill, Jan Gray Jan 2010

Funding And Secondary School Choice In Australia: A Historical Consideration, Rosemary Cahill, Jan Gray

Research outputs pre 2011

Since public funds first began to flow into non-government schools in the mid-1970s, successive Commonwealth and state governments have steadily increased the amount of funding they have provided to nongovernment schools (Bonnor & Caro, 2007; Macfarlane, 2003). The outcome of this funding decision has brought the cost of a ‘private school education’ within reach of many more Australian families in the 21st century (Rothman, 2003; Symes & Gulson, 2005). This paper explores the historical backdrop within which secondary schooling is provided in Western Australian today in order to better understand how it influences and/or predisposes the secondary school choices currently …

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In The Line Of Fire: The Challenges Of Managing Tourism Pperations In The Victorian Alps, Dale Sanders, Jennifer Laing Jan 2010

In The Line Of Fire: The Challenges Of Managing Tourism Pperations In The Victorian Alps, Dale Sanders, Jennifer Laing

Research outputs pre 2011

Understanding the impact of bushfires on tourism operations in Australian national parks and regional communities is of growing importance, with evidence of their increased frequency and severity linked, in part, to climate change. This is particularly critical for Australian alpine regions, given their greater emphasis on the summer season in the wake of lighter winter snowfalls. This article focuses on management issues and challenges of maintaining tourist operations within the Victorian Alps post-bushfire, including operator reactions to the bushfires and their subsequent implementation (or not) of crisis management and disaster recovery strategies. It is based on a qualitative study involving …

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Autonomous Bee Colony Optimization For Multi-Objective Function, F Zeng, James Decraene, Malcolm Low, Philip Hingston, C Wentong, Z Suiping, M Chandramohan Jan 2010

Autonomous Bee Colony Optimization For Multi-Objective Function, F Zeng, James Decraene, Malcolm Low, Philip Hingston, C Wentong, Z Suiping, M Chandramohan

Research outputs pre 2011

An Autonomous Bee Colony Optimization (A-BCO) algorithm for solving multi-objective numerical problems is proposed. In contrast with previous Bee Colony algorithms, A-BCO utilizes a diversity-based performance metric to dynamically assess the archive set. This assessment is employed to adapt the bee colony structures and flying patterns. This self-adaptation feature is introduced to optimize the balance between exploration and exploitation during the search process. Moreover, the total number of search iterations is also determined/optimized by A-BCO, according to user pre-specified conditions, during the search process. We evaluate A-BCO upon numerical benchmark problems and the experimental results demonstrate the effectiveness and robustness …

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Evolving Group Strategies For Ipd, Philip Hingston Jan 2010

Evolving Group Strategies For Ipd, Philip Hingston

Research outputs pre 2011

The Iterated Prisoners Dilemma (IPD) is often used to model cooperation between self-interested agents. In an earlier study, we introduced a framework using IPD to study the effects of species-level competition on the evolution of cooperative behaviour. In this paper, we extend the previous work, using co-evolutionary simulations of interactions between species of IPD-playing agents to investigate how group strategies may evolve. We find that the ability to cooperate more with agents of the same species greatly increases the ferocity of competition between species.

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A Wrapper-Based Feature Selection For Analysis Of Large Data Sets, Jinsong Leng, Craig Valli, Leisa Armstrong Jan 2010

A Wrapper-Based Feature Selection For Analysis Of Large Data Sets, Jinsong Leng, Craig Valli, Leisa Armstrong

Research outputs pre 2011

Knowledge discovery from large data sets using classic data mining techniques has been proved to be difficult due to large size in both dimension and samples. In real applications, data sets often consist of many noisy, redundant, and irrelevant features, resulting in degrading the classification accuracy and increasing the complexity exponentially. Due to the inherent nature, the analysis of the quality of data sets is difficult and very limited approaches about this issue can be found in the literature. This paper presents a novel method to investigate the quality and structure of data sets, i.e., how to analyze whether there …

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A Novel Subspace Outlier Detection Approach In High Dimensional Data Sets, Jinsong Leng Jan 2010

A Novel Subspace Outlier Detection Approach In High Dimensional Data Sets, Jinsong Leng

Research outputs pre 2011

Many real applications are required to detect outliers in high dimensional data sets. The major difficulty of mining outliers lies on the fact that outliers are often embedded in subspaces. No efficient methods are available in general for subspace-based outlier detection. Most existing subspacebased outlier detection methods identify outliers by searching for abnormal sparse density units in subspaces. In this paper, we present a novel approach for finding outliers in the ‘interesting’ subspaces. The interesting subspaces are strongly correlated with `good' clusters. This approach aims to group the meaningful subspaces and then identify outliers in the projected subspaces. In doing …

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A New Design For A Turing Test For Bots, Philip Hingston Jan 2010

A New Design For A Turing Test For Bots, Philip Hingston

Research outputs pre 2011

Interesting, human-like opponents add to the entertainment value of a video game, and creating such opponents is a difficult challenge for programmers. Can artificial intelligence and computational intelligence provide the means to convincingly simulate a human opponent? Or are simple programming tricks and deceptions more effective? To answer these questions, the author designed and organised a game bot programming competition, the BotPrize, in which competitors submit bots that try to pass a “Turing Test for Bots”. In this paper, we describe a new design for the competition, which will make it simpler to run, and, we hope, open up new …

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Groove Shape-Dependent Absorption Enhancement Of 850 Nm Msm Photodetectors With Nano-Gratings, Narottam Das, Ayman Karar, Mikhail Vasiliev, Chee Leong Tan, Kamal Alameh, Yong Tak Lee Jan 2010

Groove Shape-Dependent Absorption Enhancement Of 850 Nm Msm Photodetectors With Nano-Gratings, Narottam Das, Ayman Karar, Mikhail Vasiliev, Chee Leong Tan, Kamal Alameh, Yong Tak Lee

Research outputs pre 2011

Finite difference time-domain (FDTD) analysis is used to investigate the light absorption enhancement factor dependence on the groove shape of the nano-gratings etched into the surfaces of metal-semiconductor-metal photodetector (MSM-PD) structures. By patterning the MSM-PDs with optimized nano-gratings a significant improvement in light absorption near the design wavelength is achieved through plasmon-assisted electric field concentration effects. Simulation results show about 50 times light absorption enhancement for 850 nm light due to improved optical signal propagation through the nano-gratings.

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Absorption Enhancement Of Msm Photodetector Structure With A Plasmonic Double Grating Structure, Chee Leong Tan, Volodymyr V. Lysak, Narottam Das, Ayman Karar, Kamal Alameh, Yong Lee Jan 2010

Absorption Enhancement Of Msm Photodetector Structure With A Plasmonic Double Grating Structure, Chee Leong Tan, Volodymyr V. Lysak, Narottam Das, Ayman Karar, Kamal Alameh, Yong Lee

Research outputs pre 2011

We present finite difference time domain simulation to analyze the optical absorption enhancement of metal-semiconductor-metal photo detectors employing double plasmonic grating structures. Simulation results show that the combination of a subwavelength aperture and double nano-structured metal grating results in up to 25 times enhancement in optical absorption, in comparison to MSM photodetector structures employing only a subwavelength aperture. This improvement of the absorption enhancement is due to the coupling out function of the bottom grating structure which distributes the light to both side of the subwavelength aperture.

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Ignorant Experts: Computer And Network Security Support From Internet Service Providers, Patryk Szewczyk, Craig Valli Jan 2010

Ignorant Experts: Computer And Network Security Support From Internet Service Providers, Patryk Szewczyk, Craig Valli

Research outputs pre 2011

The paper examines the advice and support provided by seven major Internet Service Providers in Australia through late 2009 and early 2010 in relation to computer and network security. Previous research has indicated that many end-users will attempt to utilise the support provided by Internet Service Providers as a simple and effective method by which to obtain key information in regards to computer security. This paper demonstrates that in many cases the individuals working at the help desk are either reluctant to provide IT security support or have insufficient skill to provide the correct information.

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Behaviour Profiling On Mobile Devices, Fudong Li, Nathan Clarke, Maria Papadaki, Paul Dowland Jan 2010

Behaviour Profiling On Mobile Devices, Fudong Li, Nathan Clarke, Maria Papadaki, Paul Dowland

Research outputs pre 2011

Over the last decade, the mobile device has become a ubiquitous tool within everyday life. Unfortunately, whilst the popularity of mobile devices has increased, a corresponding increase can also be identified in the threats being targeted towards these devices. Security countermeasures such as AV and firewalls are being deployed, however, the increasing sophistication of the attacks requires additional measures to be taken. This paper proposes a novel behaviour-based profiling technique that is able to build upon the weaknesses of current systems by developing a comprehensive multilevel approach to profiling. In support of this model, a series of experiments have been …

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A Distributed And Cooperative User Authentication Framework, C.G. Hocking, Steven Furnell, Nathan Clarke, P L Reynolds Jan 2010

A Distributed And Cooperative User Authentication Framework, C.G. Hocking, Steven Furnell, Nathan Clarke, P L Reynolds

Research outputs pre 2011

As the requirement for companies and individuals to protect information and personal details comes more into focus, the implementation of security that goes beyond the ubiquitous password or Personal Identification Number (PIN) is paramount. With the ever growing number of us utilizing more than one device simultaneously, the problem and need is compounded. This paper proposes a novel approach to security that leverages the collective confidence of user identity held by the multiplicity of devices present at any given time. User identity confidence is reinforced by sharing established credentials between devices, enabling them to make informed judgments on their own …

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An Analysis Of Information Security Awareness Within Home And Work Environments, Shuhaili Talib, Nathan Clarke, Steven Furnell Jan 2010

An Analysis Of Information Security Awareness Within Home And Work Environments, Shuhaili Talib, Nathan Clarke, Steven Furnell

Research outputs pre 2011

As technology such as the Internet, computers and mobile devices become ubiquitous throughout society, the need to ensure our information remains secure is imperative. Unfortunately, it has long been understood that good security cannot be achieved through technical means alone and a solid understanding of the issues and how to protect yourself is required from users. Whilst many initiatives, programs and strategies have been proposed to improve the level of information security awareness, most have been directed at organizations, with a few national programs focused upon home users. Given people's use of technology is primarily focused upon those two areas: …

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An Online Ballistics Imaging System For Firearm Identification, Zhihu Huang, Jinsong Leng Jan 2010

An Online Ballistics Imaging System For Firearm Identification, Zhihu Huang, Jinsong Leng

Research outputs pre 2011

Since the traditional ballistics imaging system is dependent upon the expertise and experience of end-user, an intelligent ballistics imaging system is highly demanded to overcome the drawbacks of traditional techniques. This paper aims to develop a novel ballistics imaging system so as to combine the traditional functions with new features such as the line-scan image module, the characteristics extraction module, and the intelligent image processing module. With the help of these features, the new system can identify firearm more efficiently and effectively than the traditional techniques.

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A Novel Binarization Algorithm For Ballistics Imaging Systems, Zhihu Huang, Jinsong Leng Jan 2010

A Novel Binarization Algorithm For Ballistics Imaging Systems, Zhihu Huang, Jinsong Leng

Research outputs pre 2011

The identification of ballistics specimens from imaging systems is of paramount importance in criminal investigation. Binarization plays a key role in preprocess of recognizing cartridges in the ballistic imaging systems. Unfortunately, it is very difficult to get the satisfactory binary image using existing binary algorithms. In this paper, we utilize the global and local thresholds to enhance the image binarization. Importantly, we present a novel criterion for effectively detecting edges in the images. Comprehensive experiments have been conducted over sample ballistic images. The empirical results demonstrate the proposed method can provide a better solution than existing binary algorithms.

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Analysis Of Hu's Moment Invariants On Image Scaling And Rotation, Zhihu Huang, Jinsong Leng Jan 2010

Analysis Of Hu's Moment Invariants On Image Scaling And Rotation, Zhihu Huang, Jinsong Leng

Research outputs pre 2011

Moment invariants have been widely applied to image pattern recognition in a variety of applications due to its invariant features on image translation, scaling and rotation. The moments are strictly invariant for the continuous function. However, in practical applications images are discrete. Consequently, the moment invariants may change over image geometric transformation. To address this research problem, an analysis with respect to the variation of moment invariants on image geometric transformation is presented, so as to analyze the effect of image's scaling and rotation. Finally, the guidance is also provided for minimizing the fluctuation of moment invariants.

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Bullying In School And Cyberspace: Associations With Depressive Symptoms In Swiss And Australian Adolescents, Sonja Perren, Julian Dooley, Therese Shaw, Donna Cross Jan 2010

Bullying In School And Cyberspace: Associations With Depressive Symptoms In Swiss And Australian Adolescents, Sonja Perren, Julian Dooley, Therese Shaw, Donna Cross

Research outputs pre 2011

Background Cyber-bullying (i.e., bullying via electronic means) has emerged as a new form of bullying that presents unique challenges to those victimised. Recent studies have demonstrated that there is a significant conceptual and practical overlap between both types of bullying such that most young people who are cyber-bullied also tend to be bullied by more traditional methods. Despite the overlap between traditional and cyber forms of bullying, it remains unclear if being a victim of cyber-bullying has the same negative consequences as being a victim of traditional bullying. Method The current study investigated associations between cyber versus traditional bullying and …

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Employee Engagement With A Corporate Physical Activity Program: The Global Corporate Challenge, Pascal Scherrer, Lynnaire Sheridan, Ruth Sibson, Maria Ryan, Nadine Henley Jan 2010

Employee Engagement With A Corporate Physical Activity Program: The Global Corporate Challenge, Pascal Scherrer, Lynnaire Sheridan, Ruth Sibson, Maria Ryan, Nadine Henley

Research outputs pre 2011

Employers engage with corporate physical activity programs to foster employee wellbeing with a view to reducing the costs of absence and recruitment. This study reports on employee engagement with a commercial program, the Global Corporate Challenge, in terms of motivation, barriers, team dynamics, social aspects and self-reported physical activity levels. It uses guided introspection to explore how participation affected employee's motivation to sustain regular physical activity within the workplace setting. The program raised awareness of employees' individual physical activity levels and fostered social interaction in the workplace. Findings highlight the importance of employers providing a supportive context, fostering staff-led team …

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Inhaled Methoxyflurane And Intranasal Fentanyl For Prehospital Management Of Visceral Pain In An Australian Ambulance Service, Steven Johnston, Gary Wilkes, Jennifer Thompson, Melanie Ziman, Richard Brightwell Jan 2010

Inhaled Methoxyflurane And Intranasal Fentanyl For Prehospital Management Of Visceral Pain In An Australian Ambulance Service, Steven Johnston, Gary Wilkes, Jennifer Thompson, Melanie Ziman, Richard Brightwell

Research outputs pre 2011

Objective This study analysed the analgesic effect and changes in vital signs associated with administration of inhaled Methoxyflurane (MTX) and/or intranasal Fentanyl (INF) for prehospital management of visceral pain. Method A retrospective, observational study reviewing 1024 randomly selected records of patients with presumed visceral pain administered MTX (465), INF (397) or both (162) by the Western Australian Ambulance Service between January 2004 and February 2006. Clinical variables assessed included systolic blood pressure, pulse rate, respiration rate and Glasgow Coma Scale score. Pain was assessed utilising Visual/Verbal Analogue Scale pain scores. Results Overall effects on vital signs appeared favourable 5 min …

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A Practical Approach To Assess Depression Risk And To Guide Risk Reduction Strategies In Later Life, Osvaldo Almeida, Helman Alfonso, Jane Pirkis, Ngaire Kerse, Moira Sim, Leon Flicker, John Snowdon, Brian Draper, Gerard Byrne, Robert Goldney, Nicola Lautenschlager, Nigel Stocks, Marcia Scazufca, Martijn Huisman, Ricardo Araya, John Pfaff Jan 2010

A Practical Approach To Assess Depression Risk And To Guide Risk Reduction Strategies In Later Life, Osvaldo Almeida, Helman Alfonso, Jane Pirkis, Ngaire Kerse, Moira Sim, Leon Flicker, John Snowdon, Brian Draper, Gerard Byrne, Robert Goldney, Nicola Lautenschlager, Nigel Stocks, Marcia Scazufca, Martijn Huisman, Ricardo Araya, John Pfaff

Research outputs pre 2011

Background: Many factors have been associated with the onset and maintenance of depressive symptoms in later life, although this knowledge is yet to be translated into significant health gains for the population. This study gathered information about common modifiable and non-modifiable risk factors for depression with the aim of developing a practical probabilistic model of depression that can be used to guide risk reduction strategies. Methods: A cross-sectional study was undertaken of 20,677 community-dwelling Australians aged 60 years or over in contact with their general practitioner during the preceding 12 months. Prevalent depression (minor or major) according to the Patient …

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Vision Self-Management For Older Adults: A Randomised Controlled Trial, Sonya Girdler, Duncan P Boldy, Satvinder S Dhaliwal, Margaret Crowley, Tanya L Packer Jan 2010

Vision Self-Management For Older Adults: A Randomised Controlled Trial, Sonya Girdler, Duncan P Boldy, Satvinder S Dhaliwal, Margaret Crowley, Tanya L Packer

Research outputs pre 2011

Background/aims Ageing of the population will result in unprecedented numbers of older adults living with age-related vision loss (ARVL). Self-management models improve health outcomes and reduce healthcare costs; however, the principles have rarely been applied in low vision services. Methods A two-armed randomised controlled trial of older adults (n=77) with ARVL compared ‘usual care’ provided by a not-for-profit community agency with an extended model of care (usual care+self-management group intervention). The primary outcome variable (participation in life situations) was measured using the Activity Card Sort. Secondary outcome measures examined general health and vision-specific domains. Results The intention-to-treat analysis demonstrated that …

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