Digital Commons Network^™

Eric Davis V. T. Sniezek

2010 Decisions

USDC for the Middle District of Pennsylvania

Thomas Washam V. Michael Klopotoski

2010 Decisions

USDC for the Middle District of Pennsylvania

Usa V. Angela Larkin

2010 Decisions

USDC for the Middle District of Pennsylvania

1,2,3,4-Tetrahydroacridones As Potential Inhibitors Of Atovaquone-Resistant And Atovaquone- Susceptible P. Falciparum Isolates Tm90-C2b And W2, Lisa Luong

Honors Thesis and Capstone Projects

Malaria is one of the most significant parasitic diseases affecting mankind today, exceeding 200 million annual cases worldwide1. This disease has been a serious issue due to developed resistance to commonly available antimalarial drugs including atovaquone and artemisinin2, the most relevant modern treatment (figure 1.1). This project focuses on the preparation of 1,2,3,4- tetrahydroacridones (figure 1.2) that can be tested for their activity against P. falciparum isolates TM90-C2B (an atovaquone-resistant parasitic strain) and W2 (an atovaquone-susceptible parasite). In the past, studies have shown that endochins (4(1H)-quinolones) 3 and acridines (figure 1.1) have been found to exhibit antimalarial activity4. The research …

Flyer News, Vol. 58, No. 20 (Dec. 10, 2010), University Of Dayton

Flyer News

Student-run newspaper of the University of Dayton.

Coupling Sediment Transport And Water Quality Models, Yi Xiong

Theses and Dissertations

Sediment has profound effects on water quality. Correspondingly, water quality modeling often needs sediment transport modeling. However, simplified descriptive sediment transport was originally employed for water quality modeling, and the linkage between sediment transport models and water quality models is less developed. Therefore, the main purposes of this study were to develop general methods of coupling sediment transport and water quality models and to improve sediment transport modeling for water quality modeling. Linkage of sediment transport and water quality was discussed and a comprehensive sediment transport literature review was conducted. SEDDEER (Sediment Deposition and Erosion), a stand-alone sediment and contaminant …

Finding High Quality Hospitals In Philadelphia., Robert D. Lieberthal, Phd

College of Population Health Lectures, Presentations, Workshops

Guest lecture for PBH609 GIS Mapping. Fall, 2010 session. Philadelphia, PA.

15 PowerPoint slides.

A Comparative Study Of Embedded And Anesthetized Zebrafish In Vivo On Myocardiac Calcium Oscillation And Heart Muscle Contraction, Brian S. Muntean, Christine M. Horvat, James H. Behler, Wissam A. Aboualaiwi, Andromeda M. Nauli, Frederick E. Williams, Surya M. Nauli

Pharmacy Faculty Articles and Research

The zebrafish (Danio rerio) has been used as a model for studying vertebrate development in the cardiovascular system. In order to monitor heart contraction and cytosolic calcium oscillations, fish were either embedded in methylcellulose or anesthetized with tricaine. Using high-resolution differential interference contrast and calcium imaging microscopy, we here show that dopamine and verapamil alter calcium signaling and muscle contraction in anesthetized zebrafish, but not in embedded zebrafish. In anesthetized fish, dopamine increases the amplitude of cytosolic calcium oscillation with a subsequent increase in heart contraction, whereas verapamil decreases the frequency of calcium oscillation and heart rate. Interestingly, verapamil also …

Evolution Of The Protein-Coding Genes In The Genomes Of The Mycoplasmatales, Dipaloke Mukherjee

Theses and Dissertations

The bacterial species belonging to the order Mycoplasmatales have highly truncated genomes, and are thus ideal for studying genome evolution patterns. Fourteen members (twelve species) of this order were selected for study of genome evolution based on gene function and phylogeny. A database was constructed that consisting of the set of genes that are common to all of these species, and these genes were further subdivided based on their functions. A Bayesian phylogenetic tree was also constructed from the 16 S ribosomal DNA sequences from these species and robust clades were identified for testing the influence of selection on gene …

Effect Of Gender On Mississippi Hunter Motivations And Substitutability Of Hunting, Vanessa Carina Oquendo

Theses and Dissertations

Selfministered mail questionnaires were sent to a stratified sample of 1,000 male and 1,000 female Mississippi resident licensed hunters to determine effect of gender on hunting motivations and substitutability of hunting. Exploratory factor analysis and analysis of covariance were used to analyze hunting motivations. Logistic regression was used to determine effects of 14 independent variables on probability of resident hunters reporting a substitute activity. Males and females differed on achievement-oriented “social recognition” and “seeking stimulation” motivations and on affiliative-oriented “family togetherness” motivations. Gender had no significant effect on resident hunter probability of reporting substitute activities. Age and importance of hunting …

Detection And Characterization Of A Volatile Compound As A Response To Fall Armyworm (Spodoptera Frugiperda) Feeding In Maize (Zea Mays), Whitney Elizabeth Crow Smith

Theses and Dissertations

Maize (Zea mays) is an important agricultural crop frequently targeted by pests that pose a threat to plant development and survival. To deal with this problem, maize generates a wide variety of responses to attack by pests, from activation of woundresponse pathways to the release of volatile compounds. Several maize lines have been developed that show resistance to one common pest, the larvae of the fall armyworm (Spodoptera frugiperda). Analysis of the volatiles released by the resistant and susceptible lines in the presence and absence of the fall armyworm was conducted using SPME coupled to GC/MS. Caryophyllene, a commonly released …

A Comparative Examination Of The Nature Of Change In Macroeconomic Policies, John Hogan

Articles

This article examines the impact of economic crises on macroeconomic policies in Ireland in the late 1950s and Sweden in the early 1980s, framed within the context of the policy change literature. Each of these countries‟ responses to the crises affecting them, tempered as they were by historical and political factors, provides valuable insights into their political economies. These findings enable us to compare and contrast the nature of each crisis and the policy responses adopted. The value of such comparison is in the perspective it offers, contributing to the goal of building a body of increasingly complete explanatory theory …

Software Maintainability Measurement: A Task Complexity Perspective, Lulu He

Theses and Dissertations

Software maintainability is one of the most crucial quality attributes of a software product. Software engineering researchers and practitioners have devoted considerable effort to developing “good design” methods, rules and principles to improve software maintainability. But before we can validate the effectiveness of these methods, we first need an approach to measure software maintainability. The existing maintainability measures usually have limited scope and accuracy since they either isolate the software from its environment and focus only on the technical properties of the software, or measure a confounding effect of various factors involved in the maintenance process. Furthermore, these measures are …

Waterhammer Modeling For The Ares I Upper Stage Reaction Control System Cold Flow Development Test Article, Jonathan Hunter Williams

Theses and Dissertations

The Upper Stage Reaction Control System provides inlight three-axis attitude control for the Ares I Upper Stage. The system design must accommodate rapid thruster firing to maintain proper launch trajectory and thus allow for the possibility to pulse multiple thrusters simultaneously. Rapid thruster valve closure creates an increase in static pressure, known as waterhammer, which propagates throughout the propellant system at pressures exceeding nominal design values. A series of development tests conducted at Marshall Space Flight Center in 2009 were performed using a waterlow test article to better understand fluid characteristics of the Upper Stage Reaction Control System. A subset …

Rapid Repair Of Levee Breaches: Plug Dimension Parameterization, Elizabeth Cathleen Burg

Theses and Dissertations

Thousands of miles of levees exist in the United States and around the world and failure of these levees as a result of breaching has the potential to cause severe flooding damage. A technology, the PLUG, has been developed to temporarily reduce the flow through a levee breach as an alternative to traditional methods. This study is focused on developing initial guidance on the parameters for sizing a PLUG using a 1:100 (model:prototype) Froude scaled model. It was found that for the PLUG to effectively reduce flow through the breach, the required ratio of the PLUG length to the breach …

The Hanle Effect As A Diagnostic Of Magnetic Fields In Stellar Envelopes. V. Thin Lines From Keplerian Disks., Richard Ignace

ETSU Faculty Works

This paper focuses on the polarized profiles of resonance scattering lines that form in magnetized disks. Optically thin lines from Keplerian planar disks are considered. Model line profiles are calculated for simple field topologies of axial fields (i.e., vertical to the disk plane) and toroidal fields (i.e., purely azimuthal). A scheme for discerning field strengths and geometries in disks is developed based on Stokes Q − U diagrams for the run of polarization across line profiles that are Doppler-broadened by the disk rotation. A discussion of the Hanle effect for magnetized disks in which the magnetorotational instability (MRI) is operating …

The Wooster Voice (Wooster, Oh), 2010-12-10, Wooster Voice Editors

The Voice: 2001-2011

This is the Wooster Voice from December 10 of 2010 and it is eight pages long. The front page of this edition of the newspaper features an article about an award given to Denise Bosdorff, a professor of Communications. The other major article on the front page is about the newest project of alumnus Duncan Jones. Jones is a director, with his new project "Source Code" to be released in theaters nationwide. A section on page four looks back at a 1910 edition of the Wooster Voice. "Harry Potter and the Deathly Hallows, Part 1" is reviewed on page five. …

The Bg News December 10, 2010, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. December 10, 2010. Volume 101-Issue 73.

Spherical Nearest Neighbor Classification: Application To Hyperspectral Data, Dalton Lunga, Okan Ersoy

Department of Electrical and Computer Engineering Technical Reports

The problem of feature transformation arises in many fields of information processing, including machine learning, data compression, computer vision and geosciences applications. Here we discuss an approach that seeks a hyperspherical coordinate system preserving geodesic distances in the high dimensional hyperspectral data space. A lower dimensional hyperspherical manifold is computed using a lower rank matrix approximation algorithm combined with the recently proposed spherical embeddings method. Three spherical metrics for classification that exploits the nonlinear structure of hyperspectral imagery based on the properties of hyperspherical surfaces and their relationship with local tangent spaces are proposed. As part of experimental validation, results …

Integrating Project Change Management Learning Into An Academic Course On It Project Management, Mikaela A. Nweke Ms.

Purdue Polytechnic Directed Projects

Within project management, little attention has been devoted to controlling and facilitating changes when constraints of a project have been changed such as scope, time, cost, or quality, also known as Project Change Management (Arami, 2008). Growing statistics prove it is imperative for students finishing IT programs to acquire an understanding of project change management (PCM) for industry preparation. The U.S. spent 3.28 billion dollars on global change management and accountability projects for technology (roughly one-third of the total budget for global change) in the year 2000; this percentage still continues to rise (Goncalves, 2007). As a result, students must …

Navigation With Limited Prior Information Using Time Difference Of Arrival Measurements From Signals Of Opportunity, Christopher M. Rondeau

Theses and Dissertations

The Global Positioning System (GPS) provides world-wide availability to high-accuracy navigation and positioning information. However, the threats to GPS are increasing, and many limitations of GPS are being encountered. Simultaneously, systems previously considered as viable backups or supplements to GPS are being shut down. This creates the need for system alternatives. Navigation using signals of opportunity (SoOP) exploits any signal that is available in a given area, regardless of whether or not the original intent of the signal was for navigation. Common techniques to compute a position estimate using SoOP include received signal strength, angle of arrival, time of arrival, …

A Comparative Analysis Of Alabama Praxis Ii Examination Scores Between Online And Traditional Graduate Students At An Alabama Institution Of Higher Learning, Winston Donnie Cobb

Theses and Dissertations

The purpose of this study was to compare the Alabama Praxis II test score outcomes between students who received degrees online versus traditional students at an Alabama regional institution of higher learning. A random sample consisted of 50 online graduate students and 50 on campus graduate students. The following 2 graduate master’s degree programs were selected for this study: the Master’s of Education (M.Ed.) degree in School Counseling and the Master’s of Science in Continuing Education (M.S.C.E.) degree in Guidance Counseling. A summarization of the research questions for this study include the following: Is there a significant difference between online …

Gene Network Inference And Expression Prediction Using Recurrent Neural Networks And Evolutionary Algorithms, Heather Y. Chan

Theses and Dissertations

We demonstrate the success of recurrent neural networks in gene network inference and expression prediction using a hybrid of particle swarm optimization and differential evolution to overcome the classic obstacle of local minima in training recurrent neural networks. We also provide an improved validation framework for the evaluation of genetic network modeling systems that will result in better generalization and long-term prediction capability. Success in the modeling of gene regulation and prediction of gene expression will lead to more rapid discovery and development of therapeutic medicine, earlier diagnosis and treatment of adverse conditions, and vast advancements in life science research.

First Order Analysis Of Nitrate Loading In The Upper Elbe River Basin, Czech Republic, Daniel J. Ritter

Theses and Dissertations

Nitrate contamination of water is a worldwide issue. Nitrate is especially dangerous for young children, and may result in potentially fatal blue baby syndrome when concentration in drinking water is > 10 mg/L N-NO3. Nitrate in surface water may also lead to eutrophication. Sources of NO3- contamination include nitrate fertilizers, wastewater treatment plants, individual domestic septic systems, runoff from animal feedlots, and natural soil nitrogen. Nitrate contamination in the Elbe River drainage, covering 148,270 km2 in Germany and the Czech Republic, has been a long-term issue. This study examines the upper one-third of the basin, located almost entirely in the Czech …

Does Growth Data Make A Difference?: Teacher Decision Making Processes Using Growth Data Versus Status Data, Patricia Fox

Theses and Dissertations

This experiment examined decisions made by teachers using only status data with those made by teachers using growth and status data. Middle school math teachers from five schools within a single school division located in Virginia participated in the study. Participants were randomly assigned to either the status only or growth and status group. They were then asked to analyze a sample set of class data and complete a survey in which they rated the success of four types of students, identified teacher strengths and weaknesses, and rated their confidence in and the usefulness of the data received. Teachers with …

Relations Of Depression, Social Support, And Socio-Demographic Factors On Health Behaviors Of Mothers With Premature Infants Hospitalized In A Neonatal Intensive Care Unit (Nicu), Surbhi Kanotra

Theses and Dissertations

The present study examined the relationships of depression, social support, and socio-demographic factors on health behaviors of mothers with preterm infants hospitalized in the neonatal intensive care unit (NICU). In addition, the study also assessed the moderation effect of social support on the relationship between depression and health behaviors. Eighty-nine mothers with hospitalized infants in the central Richmond area participated in the study. Analyses found that mother’s education level and her marital status to be significantly associated with her health behaviors. Mothers with a higher level of education and those who were married, were less likely to smoke and more …

Gazette Notices - Appointment Of Staff (Notice 15895) (Corrected), Truth, Justice, And Reconciliation Commission

V. Kiplagat Tribunal and Related Documents

No abstract provided.

Equation Of State Of A Dense And Magnetized Fermion System, Efrain J. Ferrer, Vivian De La Incera, Jason P. Keith, Israel Portillo, Paul L. Springsteen

Physics & Astronomy Faculty Publications

The equation of state of a system of fermions in a uniform magnetic field is obtained in terms of the thermodynamic quantities of the theory by using functional methods. It is shown that the breaking of the O(3) rotational symmetry by the magnetic field results in a pressure anisotropy, which leads to the distinction between longitudinal- and transverse-to-the-field pressures. A criterion to find the threshold field at which the asymmetric regime becomes significant is discussed. This threshold magnetic field is shown to be the same as the one required for the pure field contribution to the energy and pressures to …

Moving Ground Target Tracking In Urban Terrain Using Air/Ground Vehicles, Timothy Mclain, Randal W. Beard, Mark Owen, Huili Yu

Faculty Publications

In this paper, we present a framework for tracking a moving target in urban environments using UAVs in cooperation with UGVs. The framework takes into account occlusions between the sensor and the target. The target state is modeled using the dynamic occupancy grid and the target motion model is built using a second-order Markov chain. Based on the target occupancy grid, we design the path planning algorithm to maneuver the UAV and the UGV to configurations where they can detect the target with high probability. Simulation results show the framework is successful in solving the target tracking problem in urban …

The Effect Of Exogenous Fructose On Creeping Bentgrass Heat Tolerance, William Brett Long

Theses and Dissertations

Creeping bentgrass (Agrostis stolonifera) used on golf course putting greens are some of the most intensively managed areas of turf and are subjected to high stress. Heat stress results in lowered photosynthetic efficiency and inadequate sugar production. An exogenous application of fructose could compensate for the lack of sugar being produced. The objectives of this research were to determine the effect of exogenous applications of fructose on heat stressed creeping bentgrass. Field results showed some phytotoxicity with high rates of fructose, while lower rates showed no visible damage compared to an untreated control. Low rates of surfactant resulted in little …