Digital Commons Network^™

The Tower, 12/15/2010

University Newspapers

No abstract provided.

Midazolam Inhibits Hippocampal Long-Term Potentiation And Learning Through Dual Central And Peripheral Benzodiazepine Receptor Activation And Neurosteroidogenesis, Kazuhiro Tokuda, Kazuko A. O'Dell, Yukitoshi Izumi, Charles F. Zorumski

Open Access Publications

Benzodiazepines (BDZs) enhance GABA(A) receptor inhibition by direct actions on central BDZ receptors (CBRs). Although some BDZs also bind mitochondrial receptors [translocator protein (18 kDa) (TSPO)] and promote the synthesis of GABA-enhancing neurosteroids, the role of neurosteroids in the clinical effects of BDZs is unknown. In rat hippocampal slices, we compared midazolam, an anesthetic BDZ, with clonazepam, an anticonvulsant/anxiolytic BDZ that activates CBRs selectively. Midazolam, but not clonazepam, increased neurosteroid levels in CA1 pyramidal neurons without changing TSPO immunostaining. Midazolam, but not clonazepam, also augmented a form of spike inhibition after stimulation adjacent to the pyramidal cell layer and inhibited …

An Algorithm For Predicting Attitudes Of Floating Bodies With Arbitrary Configurations In Liquids, Jiann-Lin Chen, Chun-I Chen, Li-Ming Chu

Journal of Marine Science and Technology–Taiwan

A robust and efficient algorithm is proposed to quasiunsteadily predict attitudes of floating bodies with arbitrary configurations. Numerical techniques for accuracy and computing time saving are addressed. A floating cylinder was modeled as a benchmark, by theoretical and experimental approaches, to validate the developed program. Attitudes of two kinds of floating bodies, which are a body composed of multiple objects and a submarine-like submersible, were simulated to show the feasibility of the present algorithm. Interestingly, the simulated results of a slender body, such as a cylinder or a submersible, show that the attitude variation is very sensitive to the longitudinal …

Intradermal Immunization Of Mice With Radiation-Attenuated Sporozoites Of Plasmodium Yoelii Induces Effective Protective Immunity, Tatiana Voza, Chahnaz Kebaier, Jerome P. Vanderberg

Publications and Research

Background Intravenous injection of mice with attenuated Plasmodium berghei sporozoites induces sterile immunity to challenge with viable sporozoites. Non-intravenous routes have been reported to yield poor immunity. Because intravenous immunization has been considered to be unacceptable for large scale vaccination of humans, assessment was made of the results of intradermal immunization of mice with Plasmodium yoelii, a rodent malaria parasite whose infectivity resembles that of human malaria. Methods Mice were immunized with two injections of isolated, radiation-attenuated P. yoelii sporozoites, either by intravenous (IV) or intradermal (ID) inoculation. In an attempt to enhance protective immunogenicity of ID-injections, one group of …

The Effects Of Chronic Ampk Activation On Hepatic Triglyceride Accumulation And Glycerol-3-Phosphate Acyltransferaseactivity With High Fat Feeding, Mary E. Curtis

Theses and Dissertations

High fat feeding increases hepatic fat accumulation and is associated with hepatic insulin resistance. AMP Activated Protein Kinase (AMPK) is thought to inhibit lipid synthesis by the acute inhibition of glycerol-3-phosphate acyltransferase (GPAT) activity and transcriptional regulation via SREBP-1c. The purpose of this study was to determine if chronic activation of AMPK prevented an increase in GPAT1 activity in rats fed a high fat diet. Rats were fed a control (C), or a high fat (HF) diet (60% fat) for 6 weeks and injected with saline or a daily AICAR dose of 0.5 mg/g body weight. Chronic AMPK activation by …

Modeling And Testing Of Dna Motion For Nanoinjection, Regis Agenor David

Theses and Dissertations

A new technique, called nanoinjection, is being developed to insert foreign DNA into a living cell. Such DNA transfection is commonly used to create transgenic organisms vital to the study of genetics, immunology, and many other biological sciences. In nanoinjection, DNA, which has a net negative charge, is electrically attracted to a micromachined lance. The lance then pierces the cell membranes, and the voltage on the lance is reversed, repelling the DNA into the cell. It is shown that DNA motion is strongly correlated to ion transport through a process called electrophoresis. Gel electrophoresis is used to move DNA using …

Glimpses Of Islam In Egypt., Madame Emilie Hyacinthe Loyson

The Open Court

No abstract provided.

Physiological Effects Of High Salinity In Teleost Fish, Janet Genz

Open Access Dissertations

Natural exposure to hypersaline environments occurs in many fish species (e.g. in tidal pools, lakes, estuaries, or due to migration). Fish in environments that are more concentrated than their extracellular fluids experience continual diffusive water loss which they combat by drinking. Intestinal Na+ and Cl- absorption drives water uptake and concentrates impermeable MgSO4 in the lumen. Epithelial Cl- absorption occurs in part by apical Cl-/HCO3- exchange, with HCO3- provided by transepithelial transport and/or by carbonic anhydrase-mediated hydration of endogenous CO2. Hydration of CO2 also liberates H+, which is excreted across either the basolateral or apical membranes. Transport of water, ions, …

Biomarkers Of Mild Cognitive Impairment And Alzheimer's Disease, Mark A. Lovell, Bert C. Lynn

Chemistry Faculty Patents

A method for quantifying a neurodegenerative disorder in a patient that includes obtaining a fluid sample from the subject; measuring a protein biomarker complex in said fluid sample and correlating the measurement with mild cognitive impairment or Alzheimer's disease status. The biomarkers include those that comprise at least one of a transthyretin protein and/or a prostaglandin-H2 D-isomerase protein, and at least one second, different protein selected from a transthyretin, prostaglandin-H2 D-isomerase, beta-2-microglobulin, cystatin C, superoxide dismutase [Cu—Zn], plasma retinol-binding protein, phosphatidylethanolamine-binding protein, carbonic anhydrase 2, prostaglandin-H2 D-isomerase, and/or serotransferrin protein.

Dachau—Remembering The Unforgettable, Jennie Gunn Ph.D., Fnp, Carroll Gunn M.A.

Journal of Health Ethics

Ethical research provides great benefit to the public, but ethical research is not guaranteed. Research can go terribly wrong when research subjects are not protected. Egos of scientists and others in power can cause disastrous results, and that is what happened at the Dachau concentration camp in Germany. Because of incidents such as this, medical research at universities is now reviewed by Institutional Review Boards to protect subjects. But not so long ago, in the Dachau concentration camp, researchers were free to impose pain and death upon prisoners in the name of research. Prisoners were mistreated to glean knowledge; many …

12/14/2010 Obituary Records, Hawaii Obituaries

Obituaries

List of Obituaries for individuals who passed away on 12/14/2010. Scroll down to see the names and obituary description.

Hotline Press Newspaper- December 2010 Vol 28 No 27, Hotline Press Newspaper

Hotline Press Newspaper 2010

No abstract provided.

Engaging Latino Adolescent Girls In Physical Activity Intervention Planning In A Low-Income, Urban Environment, Laura A. Esparza, Daisy Y. Morales-Campos, Cynthia M. Mojica, Deborah Parra- Medina

International Journal of Exercise Science: Conference Proceedings

Purpose: Latino adolescent girls are less physically active than the general adolescent population, which puts them at increased risk for obesity and chronic disease. The Physical Activity Partnership for Girls (PG) uses a community-based participatory research approach to assess community needs and priorities related to physical activity (PA) behaviors of middle school girls living in low-income, urban sectors of San Antonio, Texas. Input was sought from girls, parents, and youth-serving agencies serving the community to inform the development of an innovative PA intervention utilizing low-cost, mobile technology (texting) and social media that will be delivered through Girl Scout troops. We …

Mixed High-Fat And Stock Diet Caused A Greater Increase In Body Mass Than High-Fat Diet Alone, Katie C. Carpenter, Tiffany Davidson, Brian K. Mcfarlin

International Journal of Exercise Science: Conference Proceedings

Increased dietary palatability may lead to excess food consumption which in turn causes an excess of caloric intake and weight gain. Although most obesity studies in rodents utilize a high-fat diet, food variation, a combination of different diets for example, may actually increase body weight and fat mass beyond that of solely high-fat feeding. Purpose: To examine the changes in weight gain and body composition in mice that consume either a high-fat diet or a combination of high-fat and stock diet. Methods: 10 CD-1 male mice were randomly assigned to one of two groups based on dietary composition (N=5/group). HF …

The Impact Of Resveratrol On Diet Induced Obesity Changes In Thymic Function, Apeksha A. Gulvady, Henry P. Ciolino, Christopher A. Jolly

International Journal of Exercise Science: Conference Proceedings

Purpose: Progenitor cells, produced in the bone marrow, migrate to the thymus where the thymic microenvironment plays a critical role in their differentiation and maturation into T cells. Fat accumulates in the thymus beginning at 1 year of age, causing the thymus to gradually involute as age progresses, thus resulting in a decline in the production of mature T-cells. Obesity augments thymic fat accumulation and hastens the decline in thymic output. Resveratrol, a phytoalexin produced in plants, has also been shown to regulate fat metabolism, in an attempt to reduce hepatic fat accumulation, via 5' adenosine monophosphate-activated protein kinase (AMPK). …

An In Situ, Individual-Based Approach To Quantify Connectivity Of Marine Fish: Ontogenetic Movements And Residency Of Lingcod, Mary Anne Bishop, Brad F. Reynolds, Sean P. Powers

University Faculty and Staff Publications

As modern fishery assessments change in an effort to be more accurate and encompass the range of potential ecosystem interactions, critical information on the ecology of species including life history, intra and inter-specific competitive interactions and habitat requirements must be added to the standard fishery-dependent and independent data sets. One species whose movements and habitat associations greatly affects exploitation patterns is lingcod, Ophiodon elongatus, which support an economically important fishery along the coastal waters of the Pacific Coast of North America. High site fidelity and limited movements within nearshore areas are hypothesized to have resulted in high catchability, a …

College Voice Vol. 35 No. 10, Connecticut College

2010-2011

No abstract provided.

Conformation Dependent Monoclonal Antibodies Distinguish Different Replicating Strains Or Conformers Of Prefibrillar Aβ Oligomers, Rakez Kayed, Isabel Canto, Leonid Breydo, Suhail Rasool, Tamas Lukacsovich, Jessica Wu, Ricardo Albay, Anna Pensalfini, Stephen Yeung, Elizabeth Head, J. Lawrence Marsh, Charles Glabe

Sanders-Brown Center on Aging Faculty Publications

BACKGROUND: Age-related neurodegenerative diseases share a number of important pathological features, such as accumulation of misfolded proteins as amyloid oligomers and fibrils. Recent evidence suggests that soluble amyloid oligomers and not the insoluble amyloid fibrils may represent the primary pathological species of protein aggregates.

RESULTS: We have produced several monoclonal antibodies that specifically recognize prefibrillar oligomers and do not recognize amyloid fibrils, monomer or natively folded proteins. Like the polyclonal antisera, the individual monoclonals recognize generic epitopes that do not depend on a specific linear amino acid sequence, but they display distinct preferences for different subsets of prefibrillar oligomers. Immunological …

December 13, 2010 Reporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Daily Eastern News: December 13, 2010, Eastern Illinois University

December

No abstract provided.

Performance Of High Biomass Sorghum And Nitrogen Dynamics By The Application Of Urea, Pelleted Poultry Litter, And Class A Municipal Biosolids, Rakesh Awale

Student Theses and Dissertations

Increasing concern over the depleting fossil fuels and rising costs of chemical fertilizers have stimulated the need to find alternative crop biomass production through regionally available fertilizer sources. A field experiment was conducted to determine high biomass sorghum [(Sorghum bicolor (Moench) L.) dry matter yield, and N uptake due to application of urea, pelleted poultry litter, and class A municipal biosolids in two cropping systems of biomass sorghum and nitrogen use efficiencies of these three nutrient sources in northeast Arkansas in 2009. While urea, pelleted poultry litter, and class A municipal biosolids produced average high biomass sorghum dry matter yield …

The Roles Of Elevated Bcl-2 In Ovarian Cancer, Nicole Shree Anderson

USF Tampa Graduate Theses and Dissertations

Ovarian cancer (OC) is the second most common gynecologic cancer; however it is responsible for the most gynecologic cancer-related deaths. Apoptosis evasion is an important mechanism in OC tumorigenesis, and the prototypic anti-apoptotic protein, B-cell lymphoma 2 (Bcl-2), is often overexpressed in OC tumors. Gaining a better understanding of the mechanism(s) behind Bcl-2 overexpression and potential extra-anti-apoptotic functions of Bcl-2 could elucidate the importance of elevated Bcl-2 in OC. In the current study, I show through immunohistochemical analysis of normal, benign, and OC tissue sections, that both epithelial and stromal Bcl-2 expression decreases with OC progression. However, the number of …

Monitoring Soil Quality To Assess The Sustainability Of Harvesting Corn Stover, Douglas L. Karlen, Gary E. Varvel, Jane M.F. Johnson, John M. Baker, Shannon L. Osborne, Jeff M. Novak, Paul R. Adler, Greg W. Roth, Stuart J. Birrell

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Harvesting feedstock for biofuel production must not degrade soil, water, or air resources. Our objective is to provide an overview of field research being conducted to quantify effects of harvesting corn (Zea mays L.) stover as a bioenergy feedstock. Coordinated fi eld studies are being conducted near Ames, IA; St. Paul and Morris, MN; Mead, NE; University Park, PA; Florence, SC; and Brookings, SD., as part of the USDA-ARS Renewable Energy Assessment Project (REAP). A baseline soil quality assessment was made using the Soil Management Assessment Framework (SMAF). Corn grain and residue yield for two diff erent stover harvest rates …

A Plantation Family Wardrobe, 1825 - 1835, Jennifer Lappas

Theses and Dissertations

An examination of the Shirley Plantation Collection, Hill Carter, Mary B. Carter, their children, the plantation workers and their wardrobe between 1825 and 1835.

The Bg News December 13, 2010, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. December 13, 2010. Volume 101-Issue 74.

Stopping For Death: Plays, Poetry, And Prose, Sally Johnson

Honors Theses

Thesis consists of plays and poetry composed by Sally Johnson.

Bessi, Danny Rings

Theses

This paper Accompanies my animated short film entitled Bessi. In this paper I will describe the creation and motivation for the story of Bessi. I will also discuss my visual style and the roots from whence it came. I shall tell the reader of the techniques I used to achieve the ascetics I wanted. I will describe all the issues I had in the creation of the story and the problems I encountered as I animated. I explain the animation style I chose and why. I also discuss the animation techniques I used and why. I shall tell how my …

Evaluation Of A French 202 Website Used In A Traditional Face-To-Face Environment, Diego Gonzalo Flores

Theses and Dissertations

The Center for Teaching and Learning, Independent Study, and the Department of French and Italian at Brigham Young University collaborated to develop the French 202 Website to be used with the French 202 course. Currently, the French 202 Website is used with the French 202 Independent Study course and with the traditional face-to-face course. This evaluation focused on the French 202 Website as it is used with the traditional face-to-face course. This evaluation was conducted in conjunction with the Center for Teaching and Learning at Brigham Young University (BYU). Based on the information collected, the evaluator found that (a) faculty …

12/11/2010, Slutzker Center For International Students

Newsletters from Slutzker Center for International Services - SCIS News

No abstract provided.

South Dakota State University Graduation Exercises, December 11, 2010, Brookings South Dakota, South Dakota State University

Commencement Programs

Please be advised that the names listed in the program do not constitute official confirmation of meeting the graduation requirements. The Fall 2010 Graduation Exercises will commence with introductions by University President David L. Chicoine. Serving as honorary marshals are Ray Peterson, Assistant Professor and Director of University State Theatre, and Diane Rickerl, Associate Dean of the Graduate School. The graduation address, titled "Leadership for Tomorrow," will be delivered by Major General Maury Forsyth. Provost Laurie Stenberg Nichols, Vice President for Academic Affairs, will acknowledge student honors. Commissioning of Army officers will be by Maj. Kory L. Knight. Honorary degrees …