Digital Commons Network^™

Plasma Mediated Molecular Delivery, Richard J. Connolly

USF Tampa Graduate Theses and Dissertations

Non-viral delivery of plasmid DNA has traditionally relied upon physical forces applied directly to target tissues. These physical methods typically involve contact between an applicator and the target tissue and often cause transient patient discomfort. To overcome the contact-dependent limitations of such delivery methodologies, an atmospheric direct current plasma source was developed to deposit ionized gas molecules onto localized treatment sites. The deposition of charged species onto a treatment site can lead to the establishment of an electric field with strengths similar to those used for traditional electroporation. In vitro experiments proved that this technology could transiently permeabilize cell membranes …

Characterization Of The Esterification Reaction In High Free Fatty Acid Oils, Lucas Eli Porter Altic

USF Tampa Graduate Theses and Dissertations

Energy and vegetable oil prices have caused many biodiesel producers to turn to waste cooking oils as feedstocks. These oils contain high levels of free fatty acids (FFAs) which make them difficult or impossible to convert to biodiesel by conventional production methods. Esterification is required for ultra-high FFA feedstocks such as Brown Grease. In addition, ultrasonic irradiation has the potential to improve the kinetics of the esterification reaction. 2-level, multi-factor DOE experiments were conducted to characterize the esterification reaction in ultra-high FFA oils as well as determine whether ultrasonic irradiation gives any benefit besides energy input. The study determined that …

Endothelial Cell Capture Of Heparin-Binding Growth Factors Under Flow, Bing Zhao, Changjiang Zhang, Kimberly Forsten-Williams, Jun Zhang, Michael Fannon

Ophthalmology and Visual Science Faculty Publications

Circulation is an important delivery method for both natural and synthetic molecules, but microenvironment interactions, regulated by endothelial cells and critical to the molecule's fate, are difficult to interpret using traditional approaches. In this work, we analyzed and predicted growth factor capture under flow using computer modeling and a three-dimensional experimental approach that includes pertinent circulation characteristics such as pulsatile flow, competing binding interactions, and limited bioavailability. An understanding of the controlling features of this process was desired. The experimental module consisted of a bioreactor with synthetic endothelial-lined hollow fibers under flow. The physical design of the system was incorporated …

October 28, 2010, James Madison University

The Breeze, 2010-2019

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

The Pacifican October 28, 2010, University Of The Pacific

All Issues - Student Newspaper, The Pacifican, Pacific Weekly

No abstract provided.

Eastern Progress - 28 Oct 2010, Eastern Kentucky University

Eastern Progress 2010-2011

No abstract provided.

Commonwealth Times 2010-10-28 [Front Page Has 2010-11-28]

Commonwealth Times, 1969-

No abstract provided.

Unh Awarded $700k For Dairy Farm Ghg Emissions Study, David Sims

Media Relations

No abstract provided.

The Murray Ledger And Times, October 28, 2010, The Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.

Conserved Genes Act As Modifiers Of Invertebrate Smn Loss Of Function Defects, Maria Dimitriadi, James N. Sleigh, Amy Walker, Howard C. Chang, Anindya Sen, Geetika Kalloo, Jevede Harris, Tom Barsby, Melissa B. Walsh, John S. Satterlee, Chris Li, David Van Vactor, Spyros Artavanis-Tsakonas, Anne C. Hart

Publications and Research

Spinal Muscular Atrophy (SMA) is caused by diminished function of the Survival of Motor Neuron (SMN) protein, but the molecular pathways critical for SMA pathology remain elusive. We have used genetic approaches in invertebrate models to identify conserved SMN loss of function modifier genes. Drosophila melanogaster and Caenorhabditis elegans each have a single gene encoding a protein orthologous to human SMN; diminished function of these invertebrate genes causes lethality and neuromuscular defects. To find genes that modulate SMN function defects across species, two approaches were used. First, a genome-wide RNAi screen for C. elegans SMN modifier genes was undertaken, yielding …

A Single-Chip Ultra-Wideband Based Wireless Sensor Network Node, Nathan R. Schemm

Department of Electrical and Computer Engineering: Dissertations, Theses, and Student Research

This dissertation presents the design of a next-generation wireless sensor network node. The node incorporates many new and innovative technologies such as an ultra-wideband radio which allows very low-energy communication, a low-power radiation detection front end, and an efficient implementation of dynamic voltage scaling which improves the energy efficiency of the integrated processor. The complete design is integrated on a single chip for maximum power savings and minimal size.

The ultra-wideband transceiver includes many novel techniques to produce a receiver with low power consumption and fast and accurate packet acquisition and reception. These include the use of a standard symmetric …

October 28, 2010, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Identification And Optimization Of Classifier Genes From Multi-Class Earthworm Microarray Dataset, Ying Li, Nan Wang, Chaoyang Zhang, Ping Gong

Faculty Publications

Monitoring, assessment and prediction of environmental risks that chemicals pose demand rapid and accurate diagnostic assays. A variety of toxicological effects have been associated with explosive compounds TNT and RDX. One important goal of microarray experiments is to discover novel biomarkers for toxicity evaluation. We have developed an earthworm microarray containing 15,208 unique oligo probes and have used it to profile gene expression in 248 earthworms exposed to TNT, RDX or neither. We assembled a new machine learning pipeline consisting of several well-established feature filtering/selection and classification techniques to analyze the 248-array dataset in order to construct classifier models that …

Mustang Daily, October 28, 2010

Cal Poly Student Newspaper

Student newspaper of California Polytechnic State University, San Luis Obispo, CA.

A Fish Out Of Water: Gill And Skin Remodeling Promotes Osmo- And Ionoregulation In The Mangrove Killifish Kryptolebias Marmoratus, Danielle M. Leblanc, Chris M. Wood, Douglas S. Fudge, Patricia A. Wright

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

The euryhaline, amphibious mangrove killifish Kryptolebias marmoratus is known to survive weeks out of water in moist environments. We tested the hypothesis that the skin is a site of osmo- and ionoregulation in K. marmoratus. We predicted that under terrestrial conditions, gill and skin remodeling would result in an enhanced role for skin and a diminished role for the gills in osmo- and ionoregulation. Fish were exposed to water—either freshwater (FW, 1‰) or hypersaline water (saltwater [SW], 45‰)—or air over a moist surface of FW or SW for 9 d and then recovered in water. When fish were emersed …

Where Christmas Begins

News Releases

No abstract provided.

Hawks' Herald -- October 28, 2010, Roger Williams University

Hawk's Herald

No abstract provided.

The Bg News October 28, 2010, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. October 28, 2010. Volume 101-Issue 47.

The East Texan, 2010-10-28, Texas A&M University-Commerce

All Issues

Volume XCV, number 9 of The East Texan, a student newspaper published at Texas A&M University-Commerce.

Vista: October 28, 2010, University Of San Diego

USD Vista (1965-)

No abstract provided.

Spectrum, Volume 27, Issue 6, Sacred Heart University

Newspapers (Obelisk & Spectrum)

Highlights Include: Make Your Vote Count for Midterm Elections -- Volunteers Help Bridgeport 'Feel the Warmth' -- Seattle University Strives to Save Environment -- Editorials -- Dance Team 'Jumps on It' -- A Day in the Life: Sacred Heart Ice Hockey

Otter Realm, October 28, 2010, California State University, Monterey Bay

The Otter Realm

AS & OSU Students Helping Students Get the Best Out of College -- You Otter Be Doing Oct.28 - Nov. 10 --For Unlawful Carnal Knowledge -- The Dharma of the Dalai Lama -- Save the Rainforests & Breathe Easier -- Students Promote "End The War Rally" -- Signed With an X: Poets Speak about Immigration -- Cal Sate Monterey Attends Ethics Conference -- You Otter Have a Safe Halloween! -- Santa Cruz Politics: Prepare for Trick or Treat -- Staff of the Issue: Steven Levinson -- Student of the Issue: Rheann Fall -- AS vs. OSU Whose running the show? …

Enhancing Virus Surveillance Through Metagenomics: Water Quality And Public Health Applications, Karyna Rosario-Cora

USF Tampa Graduate Theses and Dissertations

Monitoring viruses circulating in the human population and the environment is critical for protecting public and ecosystem health. The goal of this dissertation was to incorporate a viral metagenomic approach into virus surveillance efforts (both clinical and water quality control programs) to enhance traditional virus detection methods.

Clinical surveillance programs are designed to identify and monitor etiological agents that cause disease. However, the ability to identify viruses may be compromised when novel or unsuspected viruses are causing infection since traditional virus detection methods target specific known pathogens. Here we describe the successful application of viral metagenomics in a clinical setting …

Quaker Campus, October 28, 2010 (Vol. 97, Issue 8), Whittier College

Quaker Campus

No abstract provided.

Ernest Hemingway’S Mistresses And Wives: Exploring Their Impact On His Female Characters, Stephen E. Henrichon

USF Tampa Graduate Theses and Dissertations

“Conflicted” succinctly describes Ernest Hemingway. He had a strong desire to make his parents proud of him but this was in constant conflict with his need to tell a story, warts and all. Of particular importance is his relationship with his mother and the crippling effect it has on his relationships with women. Hemingway’s life becomes a series of dysfunctional relationships that fail to meet his needs, leaving him perpetually searching for the right woman. Kert posits that Hemingway’s contempt for women is related to his inability to make the transition from lover to husband, fueled by Hemingway’s belief that …

Rethinking Ethical Naturalism: The Implications Of Developmental Systems Theory, Jared J.. Kinggard

USF Tampa Graduate Theses and Dissertations

Biological research has the capacity to inform ethical discussions. There are numerous questions about the nature of sexual orientation, intelligence, gender identity, etc., and many of these questions are commonly approached with the benefit of implicit or explicit biological commitments. The answers to these sorts of questions can have a powerful impact on social, ethical, and political positions. In this project I examine the prospect of naturalizing ethics under the umbrella of developmental systems theory (DST). If one is committed to DST, then those ideas involved in DST that steer biological research will also have implications for ethics. There has …

Puerperal Fever In Britain: Failed Models Of Disease Causation, Jessica Wells

USF Tampa Graduate Theses and Dissertations

In eighteenth- and nineteenth-century Britain, a bacterial infection which we now

know to be caused primarily by a streptococcus, was killing women in childbirth at an

alarming rate. The disease, called puerperal, or childbed, fever, was being transmitted

primarily from doctor to patient by a doctor’s unwashed hands and filthy, contaminated

clothing and linens. Despite this evident and, in retrospect, obvious vector, the doctors of

this period never discovered how to prevent their patients from dying a gruesome and

painful death. Many physicians wrote extensive accounts of the illness but often ended

their works in despair, unable to find the …

Lanthorn, Vol. 45, No. 19, October 28, 2010, Grand Valley State University

Volume 45, July 8, 2010 - June 9, 2011

Lanthorn is Grand Valley State's student newspaper, published from 1968 to the present.

Spartan Daily October 27, 2010, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily (School of Journalism and Mass Communications)

Volume 135, Issue 32

Fs Minutes 2010-10-27, Northern Illinois University

Faculty Senate Archives

No abstract provided.