Digital Commons Network^™

Cerenkov Radiation Energy Transfer (Cret) Imaging: A Novel Method For Optical Imaging Of Pet Isotopes In Biological Systems, Robin S. Dothager, Reece J. Goiffon, Erin Jackson, Scott Harpstrite, David Piwnica-Worms

Open Access Publications

No abstract provided.

Tip-1 Translocation Onto The Cell Plasma Membrane Is A Molecular Biomarker Of Tumor Response To Ionizing Radiation, Hailun Wang, Heping Yan, Allie Fu, Miaojun Han, Dennis Hallahan, Zhaozhong Han

Open Access Publications

No abstract provided.

Transgenic Overexpression Of Active Calcineurin In Beta-Cells Results In Decreased Beta-Cell Mass And Hyperglycemia, Ernesto Bernal-Mizrachi, Corentin Cras-Meneur, Bo Ra Ye, James D. Johnson, M. Alan Permutt

Open Access Publications

No abstract provided.

The Caenorhabditis Elegans Kinesin-3 Motor Unc-104/ Kif1a Is Degraded Upon Loss Of Specific Binding To Cargo, Jitendra Kumar, Bikash C. Choudhary, Raghu Metpally, Qun Zheng, Michael L. Nonet, Sowdhamini Ramanathan, Dieter R. Klopfenstein, Sandhya P. Koushika

Open Access Publications

No abstract provided.

Detection Of Wuchereria Bancrofti L3 Larvae In Mosquitoes: A Reverse Transcriptase Pcr Assay Evaluating Infection And Infectivity, Sandra J. Laney, Reda M. R. Ramzy, Hanan H. Helmy, Hoda A. Farid, Ameen A. Ashour, Gary J. Weil, Steven A. Williams

Open Access Publications

No abstract provided.

Surface Properties Of Helicobacter Pylori Urease Complex Are Essential For Persistence, Tobias D. Schoep, Alma Fulurija, Fayth Good, Wei Lu, Robyn P. Himbeck, Carola Schwan, Sung Sook Choi, Douglas E. Berg, Peer R.E. Mittl, Mohammed Benghezal, Barry J. Marshall

Open Access Publications

No abstract provided.

Ips-1 Is Essential For The Control Of West Nile Virus Infection And Immunity, Mehul S. Suthar, Daphne Y. Ma, Sunil Thomas, Jennifer M. Lund, Nu Zhang, Stephane Daffis, Alexander Y. Rudensky, Michael J. Bevan, Edward A. Clark, Murali-Krishna Kaja, Michael S. Diamond, Michael Gale Jr.

Open Access Publications

No abstract provided.

Low-Density Lipoprotein Receptor-Related Protein 1 (Lrp1) Mediates Neuronal Abeta42 Uptake And Lysosomal Trafficking, Rodrigo A. Fuentealba, Qiang Liu, Juan Zhang, Takahisa Kanekiyo, Xiaoyan Hu, Jin-Moo Lee, Mary Jo Ladu, Guojun Bu

Open Access Publications

No abstract provided.

Identification Of Hookworm Daf-16/Foxo Response Elements And Direct Gene Targets, Xin Gao, Zhengyuan Wang, John Martin, Sahar Abubucker, Xu Zhang, Makedonka Mitreva, John M. Hawdon

Open Access Publications

No abstract provided.

Leishmania Major Survival In Selective Phlebotomus Papatasi Sand Fly Vector Requires A Specific Scg-Encoded Lipophosphoglycan Galactosylation Pattern, Deborah E. Dobson, Shaden Kamhawi, Phillip Lawyer, Salvatore J. Turco, Stephen M. Beverley, David L. Sacks

Open Access Publications

No abstract provided.

Multiple Phosphatidylinositol 3-Kinases Regulate Vaccinia Virus Morphogenesis, Shannon Mcnulty, William Bornmann, Jill Schriewer, Chas Werner, Scott K. Smith, Victoria A. Olson, Inger K. Damon, R. Mark Buller, John Heuser, Daniel Kalman

Open Access Publications

No abstract provided.

Six Rna Viruses And Forty-One Hosts: Viral Small Rnas And Modulation Of Small Rna Repertoires In Vertebrate And Invertebrate Systems, Poornima Parameswaran, Ella Sklan, Courtney Wilkins, Trever Burgon, Melanie A. Samuel, Rui Lu, K. Mark Ansel, Vigo Heissmeyer, Shirit Einav, William Jackson, Tammy Doukas, Suman Paranjape, Charlotta Polacek, Flavia Barreto Dos Santos, Roxana Jalili, Farbod Babrzadeh, Baback Gharizadeh, Dirk Grimm, Mark Kay, Satoshi Koike, Peter Sarnow, Mostafa Ronaghi, Shou-Wei Ding, Eva Harris, Marie Chow, Michael S. Diamond, Karla Kirkegaard, Jeffrey S. Glenn, Andrew Z. Fire

Open Access Publications

No abstract provided.

A Pparalpha Promoter Variant Impairs Err-Dependent Transactivation And Decreases Mortality After Acute Coronary Ischemia In Patients With Diabetes, Sharon Cresci, Janice M. Huss, Amber L. Beitelshees, Philip G. Jones, Matt R. Minton, Gerald W. Dorn Ii, Daniel P. Kelly, John A. Spertus, Howard L. Mcleod

Open Access Publications

No abstract provided.

Atopic Dermatitis-Like Disease And Associated Lethal Myeloproliferative Disorder Arise From Loss Of Notch Signaling In The Murine Skin, Alexis Dumortier, Andre-Dante Durham, Matteo Di Piazza, Sophie Vauclair, Ute Koch, Gisele Ferrand, Isabel Ferrero, Shadmehr Demehri, Lynda Li Song, Andrew G. Farr, Warren J. Leonard, Raphael Kopan, Lucio Miele, Daniel Hohl, Daniel Finke, Freddy Radtke

Open Access Publications

No abstract provided.

Endosymbiont Dna In Endobacteria-Free Filarial Nematodes Indicates Ancient Horizontal Genetic Transfer, Samantha N. Mcnulty, Jeremy M. Foster, Makedonka Mitreva, Julie C. Dunning Hotopp, John Martin, Kerstin Fischer, Bo Wu, Paul J. Davis, Sanjay Kumar, Norbert W. Brattig, Barton E. Slatko, Gary J. Weil, Peter U. Fischer

Open Access Publications

No abstract provided.

Gene-Gene Interactions Lead To Higher Risk For Development Of Type 2 Diabetes In An Ashkenazi Jewish Population, Rosalind J. Neuman, Jon Wasson, Gil Atzmon, Julio Wainstein, Yair Yerushalmi, Joseph Cohen, Nir Barzilai, Ilana Blech, Benjamin Glaser, M. Alan Permutt

Open Access Publications

No abstract provided.

Mitochondrial Dysfunction And Apoptosis In Cumulus Cells Of Type I Diabetic Mice, Qiang Wang, Antonina I. Frolova, Scott Purcell, Katie Adastra, Erica Schoeller, Maggie M. Chi, Tim Schedl, Kelle H. Moley

Open Access Publications

No abstract provided.

Genome Sequencing Reveals Widespread Virulence Gene Exchange Among Human Neisseria Species, Pradeep Reddy Marri, Mary Paniscus, Nathan J. Weyand, Maria A. Rendon, Christine M. Calton, Diana R. Hernandez, Dustin L. Higashi, Erica Sodergren, George M. Weinstock, Steven D. Rounsley, Magdalene So

Open Access Publications

No abstract provided.

Inclusive Teaching Circles : Mechanisms For Creating Welcoming Classrooms., Sharon E. Moore, Sherri L. Wallace, Gina Schack, M. Shelley Thomas, Linda Lewis, Linda Wilson, Shawnise Miller, Joan D'Antoni

Faculty and Staff Scholarship

This essay examines the Inclusive Teaching Circle (ITC) as a mechanism for faculty development in creating instructional tools that embrace an inclusive pedagogy reflecting diversity, cultural competence and social justice. We describe one group’s year-long participation in an ITC at a large, metropolitan research university in the south. Next, we share several members’ strategies for promoting more inclusive and equitable learning for students in our classrooms. Finally, we consider the implications of ITCs for its group participants and the professorate at large.

Mechanisms Of Apoptosis In Crustacea : What Conditions Induce Versus Suppress Cell Death?, Michael Menze, Grady Fortner, Suman Nag, Steven Hand

Faculty and Staff Scholarship

Arthropoda is the largest of all animal phyla and includes about 90% of extant species. Our knowledge about regulation of apoptosis in this phylum is largely based on findings for the fruit fly Drosophila melanogaster. Recent work with crustaceans shows that apoptotic proteins, and presumably mechanisms of cell death regulation, are more diverse in arthropods than appreciated based solely on the excellent work with fruit flies. Crustacean homologs exist for many major proteins in the apoptotic networks of mammals and D. melanogaster, but integration of these proteins into the physiology and pathophysiology of crustaceans is far from complete. Whether apoptosis …

Rethinking Guardianship (Again): Substituted Decision Making As A Violation Of The Integration Mandated Of Title Ii Of The Americans With Disabilities Act, Leslie Salzman

Articles

In every state, when an adult has a diminished capacity to make decisions about personal affairs or property management, a court may transfer the individual’s right to make decisions to a guardian. This Article argues that, in most cases, it would be preferable to support decision making rather than supplant it through guardianship, and then seeks to locate a right to receive such support as a less restrictive alternative to the substituted decision making that characterizes guardianship.

Building on the reasoning in Olmstead v. L.C. and subsequent decisions interpreting the Americans with Disabilities Act’s integration mandate, this Article argues that …

The Future Of Disparate Impact, Richard A. Primus

Articles

The Supreme Court's decision in Ricci v. DeStefano foregrounded the question of whether Title VIl's disparate impact standard conflicts with equal protection. This Article shows that there are three ways to read Ricci, one of which is likely fatal to disparate impact doctrine but the other two of which are not.

Trademark And Copyright In The Days Of Internet: The Google Influence, Michael H. Baniak, Matthew Sag

Northwestern Journal of Technology and Intellectual Property

No abstract provided.

Critical Oxygen Levels And Metabolic Suppression In Oceanic Oxygen Minimum Zones, Brad A. Seibel

Biological Sciences Faculty Publications

The survival of oceanic organisms in oxygen minimum zones (OMZs) depends on their total oxygen demand and the capacities for oxygen extraction and transport, anaerobic ATP production and metabolic suppression. Anaerobic metabolism and metabolic suppression are required for daytime forays into the most extreme OMZs. Critical oxygen partial pressures are, within a range, evolved to match the minimum oxygen level to which a species is exposed. This fact demands that low oxygen habitats be defined by the biological response to low oxygen rather than by some arbitrary oxygen concentration. A broad comparative analysis of oxygen tolerance facilitates the identification of …

Tracking The Oxidative Kinetics Of Carbohydrates, Amino Acids And Fatty Acids In The House Sparrow Using Exhaled 13Co2, Marshall D. Mccue, O. Sivan, Scott R. Mcwilliams, B. Pinshow

Natural Resources Science Faculty Publications

Clinicians commonly measure the ¹³CO₂ in exhaled breath samples following administration of a metabolic tracer (breath testing) to diagnose certain infections and metabolic disorders. We believe that breath testing can become a powerful tool to investigate novel questions about the influence of ecological and physiological factors on the oxidative fates of exogenous nutrients. Here we examined several predictions regarding the oxidative kinetics of specific carbohydrates, amino acids and fatty acids in a dietary generalist, the house sparrow (Passer domesticus). After administering postprandial birds with 20 mg of one of seven ¹³C-labeled tracers, we measured rates …

State Of Utah V. Riqo M. Perea : Brief Of Appellant, Utah Supreme Court

Utah Supreme Court Briefs (2000–2020)

Appeal from a conviction for two counts of Aggravated Murder in violation of Utah Code Ann. § 76-5-202, two counts of Attempted Murder in violation of Utah Code Ann. § 76-5-203 and a Dangerous Weapon Enhancement in violation of Utah Code Ann. § 76-4-203 in the Second District Court, State of Utah, the Honorable Ernie W. Jones, Judge, presiding.

Close Encounters Of Three Kinds: On Teaching Dominance Feminism And Intersectionality, Kimberlé W. Crenshaw

Faculty Scholarship

I am pleased to be a part of this symposium honoring Catharine MacKinnon's groundbreaking work as a feminist theorist, legal advocate, and global activist. This invitation not only presents the opportunity to examine the interface between dominance theory and intersectionality, but also the occasion to delve further into the vexed rhetorical politics surrounding feminism and antiracism.

By now the fact that there has been a contested relationship between antiracism and feminism is almost axiomatic.1 Yet as with most things that have become matters of common knowledge, there is a risk that generalizations can metastasize into hardened conclusions that obscure rather …

Emerging Vaccine Informatics, Yongqun He, Rino Rappuoli, Anne S. De Groot, Robert T. Chen

Institute for Immunology and Informatics Faculty Publications

Vaccine informatics is an emerging research area that focuses on development and applications of bioinformatics methods that can be used to facilitate every aspect of the preclinical, clinical, and postlicensure vaccine enterprises. Many immunoinformatics algorithms and resources have been developed to predict T- and B-cell immune epitopes for epitope vaccine development and protective immunity analysis. Vaccine protein candidates are predictable in silico from genome sequences using reverse vaccinology. Systematic transcriptomics and proteomics gene expression analyses facilitate rational vaccine design and identification of gene responses that are correlates of protection in vivo. Mathematical simulations have been used to model host-pathogen interactions …

New Media Globalization In Asia: The Online Game Industries Of South Korea, Singapore, And China, Peichi Chung

Iowa Journal of Communication

This paper examines the emerging media flow in the new media economy of Asia by focusing on the networking of media exchange among three growing production centers. It argues that the nation-state has come to play an increasingly important role in the development of a pan-Asian cultural economy in the online gaming industries of Asia. New cultural production centers have created a rising regional growth corridor between South Korea, Singapore and China. This paper concludes that this emerging growth corridor in Asia redefines the power relationship between core and periphery in the global media industry in ways that affect the …

Financialization Of The Asian Game Industry: A New Business Model, Dal Young Jin

Iowa Journal of Communication

This study is a historical documentation of the recent trends of financialization, mainly to ascertain whether these trends are confirmation that financialization plays a pivotal role in the game market in the midst of the global economic crisis in the early 21st century. The major focus will not only be on capital flow but also on financing, which means that the paper is to map out the way in which the Asian game industry has been part of the transnationalization process in order to fully understand the nature of globalization. Eventually, it examines whether the financialization of the online game …