Digital Commons Network^™

A Timp2-Armed Conditionally-Replicating Adenovirus For The Treatment Of Ovarian Cancer, Sherry Wei Yang

All ETDs from UAB

Ovarian cancer remains the most lethal gynecological malignancy in the U.S. Conventional therapies have limited therapeutic value due to advanced stage of the disease at diagnosis. Conditionally-replicating adenoviruses (CRAds) are promising, novel anti-cancer agents that are designed to selectively replicate in and lyse tumor cells. In clinical trials, CRAds exhibited limited efficacy thus far. Second generation CRAds are being developed to express a therapeutic protein to further enhance antitumor efficacy. One attractive target in ovarian tumor microenvironment is the matrix metalloproteinases (MMPs) that degrade the extracellular matrix. Thus, tissue inhibitor of metalloproteinase 2 (TIMP2), an endogenous inhibitor of MMPs, is …

Cross-Talk Between Marginal Zone B Cells And Marginal Zone Macrophages, Yuying You

All ETDs from UAB

the test of group differences and the test of covariate. When we force the predictors in the

A State Of Rightlessness: The Egregious Case Of North Korea, Morse Tan

Faculty Articles, Papers, and Other Scholarship

This essay steps into the relative dearth of popular and legal academic treatment to analyze this egregious state of rightlessness (an intentional neologism) and concludes with reflections upon possible judicial redress options. Experts in the human rights field have averred that the human rights situation in North Korea is the worst in the world. The North Korean government denies any human rights abuses, insisting “that 'there is no human rigths [sic] problem in North Korea.'" This academic work challenges this outright denial by providing an analysis of various human rights abuses persisting north of the most heavily armed border in …

Phylogenetically Widespread Multiple Paternity In New World Natricine Snakes, Richard B. King, W. Scott Grayburn, Melvin R. Duvall, Theresa L. Wusterbarth, Gordon M. Burghardt

Faculty Articles, Papers, and Other Scholarship

We used microsatellite DNA markers to identify the extent to which multiple paternity within litters occurs among species of New World natricine snakes. We selected seven species to represent the three major clades of Natricinae and all three subclades of the gartersnake clade. Microsatellite DNA genotyping of dams and litters confirmed multiple paternity within litters of six species, including Thamnophis radix, T. sauritus, Storeria dekayi, S. occipitomaculata, Nerodia rhombifer, and Regina septemvittata. Multiple paternity was not evident in one litter of nine Thamnophis melanogaster. Together with published data documenting multiple paternity in T. bulteri, T. elegans, T. sirtalis, and N. …

Seabird Islands Take Mere Decades To Recover Following Rat Eradication, Holly P. Jones

Faculty Articles, Papers, and Other Scholarship

Islands house a majority of the world’s biodiversity and are thus critical for biodiversity conservation. Seabird nesting colonies provide nutrients that are integral to maintain island biodiversity and ecosystem function. Invasive rats destroy seabird colonies and thus the island ecosystems that depend on seabird-derived nutrients. After rat eradication, it is unclear how long ecosystem recovery may take, although some speculate on the order of centuries. I looked at ecosystem recovery along a chronosequence of islands that had 12–22 years to recover following rat eradication. I show that soil, plant, and spider marine-derived nitrogen levels and C:N ratios take mere decades …

The Impact Of Direct And Indirect Experiences On The Development Of Environmental Knowledge, Attitudes, And Behavior, Mat D. Duerden, Peter A. Witt

Faculty Publications

This study employed a mixed-methods design to examine the relationship between nature experience type (e.g., direct and indirect) and learning outcomes (e.g., environmental knowledge, attitudes, and behavior) associated with an environmental education, international immersion program for adolescents. Longitudinal data from 108 participant and 49 comparison group members were analyzed to test the study’s hypotheses. Additionally, qualitative data were analyzed using grounded theory methodology to assess participants’ perceptions of these processes. The findings indicate that environmental knowledge increased more than environmental attitudes during the indirect portion of the program (i.e., preparatory program) whereas the direct portion (i.e., international workshop) produced similar …

“Why Does Google Scholar Sometimes Ask For Money?” Engaging Science Students In Scholarly Communication And The Economics Of Information, Scott Warren, Kim Duckett

Librarian Publications

This article outlines instructional strategies for teaching students about scholarly communication and the economic realities that surround scientific information. Exposing students to the business side of academic communication provides a foundation for understanding how Google relates to library-subscription resources, how research is both shared and discovered, what the role of libraries is in providing access to costly information, and how disparities arise in information access. Such instruction contextualizes search tools such as article databases as well as Google Scholar, and thereby serves as an appropriate starting point for teaching students to use such tools.

Numerical Simulation And First-Order Hazard Analysis Of Large Co-Seismic Tsunamis Generated In The Puerto Rico Trench: Near-Field Impact On The North Shore Of Puerto Rico And Far-Field Impact On The Us East Coast, Stephan T. Grilli, S. Dubosq, N. Pophet, Y. Pérgnon, J. T. Kirby, F. Shi

Ocean Engineering Faculty Publications

We perform numerical simulations of the coastal impact of large co-seismic tsunamis, initiated in the Puerto Rican trench, both in far-field areas along the upper US East coast (and other Caribbean islands), and in more detail in the near-field, along the Puerto Rico North Shore (PRNS). We first model a magnitude 9.1 extreme co-seismic source and then a smaller 8.7 magnitude source, which approximately correspond to 600 and 200 year return periods, respectively. In both cases, tsunami generation and propagation (both near- and far-field) are first performed in a coarse 2′ basin scale grid, with ETOPO2 bathymetry, using a fully …

Writing On Biblical Punishments, Donas Jackson Haymes

Donas Jackson Haymes Papers

No abstract provided.

Language Matters: Some New Contributions From Sociology (Emanating From Richard Brecht’S Castle), John P. Robinson, William P. Rivers, Cynthia Costell, Jennifer Robinson

Russian Language Journal

As a result of the projects undertaken by the University of Maryland’s Center for the Advanced Study of Language, several new findings and insights have emerged from the highest quality data collections on Americans’ abilities in and attitudes toward foreign languages (FL). These involve the (now annual) language surveys conducted by the US Census Bureau and the bi-­‐‑annual General Social Survey (GSS) conducted by the University of Chicago since 1972. The Census Bureau has been documenting foreign languages spoken at home and how well individuals can speak English in such households. The 2000-­‐‑08 GSS has assessed whether adults can speak …

Constitutional Theology: The Revival Of Whig History In American Public Law, William J. Novak

Articles

One of the things I admire about the profession of history is that there are no admissions requirements. Like being a novelist or a member of Congress, the door is open to almost anyone who wants to try their hand at the art or craft. In a world of an increasingly specialized division of professional labor, that is a relatively rare and special thing. Though I teach in a law school, for example, I would be in trouble if I tried to pass myself off as a lawyer. Though I could perhaps irritatingly refer to myself as a doctor owing …

Anterior Cruciate Ligament Reconstruction Results In Alterations In Gait Variability, Constantina O. Moraiti, Nikolaos Stergiou, Haris S. Vasiliadis, Eustathios Motsis, Anastasios D. Georgoulis

Journal Articles

Introduction: The temporal structure of gait variability has shown that healthy human gait exhibits long- range correlations and deterministic properties which allow the neuromuscular system to be flexible and adaptable to stresses. Pathology results in deterioration of these properties. We examined structure of gait variability after ACL reconstruction with either BPTB or quadrupled ST/G tendon autografts.

Methods: Six patients with BPTB reconstruction, six with ST/G reconstruction and six healthy controls walked on a treadmill at their self-selected pace. Two minutes of continuous kinematic data were recorded with a 6-camera optoelectronic system. The nonlinear measure of the largest Lyapunov …

Faculty Publications 2009, Lsu Health Sciences Center New Orleans

Historical Faculty Publications

This Faculty bibliography contains 806 publications.

Technical Efficiency Of Farmers In Ethiopia: A Stochastic Production Frontier Approach, Askal Ayalew Ali

Masters Theses

This study is to investigate the farmer's efficiency in Ethiopia. The stochastic production function is applied to estimate the technical efficiency of farmers. Using 2006 survey data conducted by the World Bank in collaboration with Ethiopian Economic Policy Research Institute, shows that farmers produce under the production frontier, and the average technical efficiency of the farmers is 62.4 percent. Variation in efficiency comes from many factors, however, this study focuses on extension program participation, education, and land ownership. Lack of extension program and education cause inefficiencies of 59.8 percent and 60.21 percent respectively. Land ownership is found to have mixed …

Frederick Douglass: The Man, His Words And His Legacy As A Master Rhetorician, Tameka Lashean Johnson

Masters Theses

This thesis offers a synthesis of existing research regarding not only Frederick Douglass· literacy in the slave narrative genre. but also an Aristotelian analysis of his Narrative of the Life of Frederick Douglass, An American Slave, Written by Himself (1845). Dougiass' challenge is to reach an audience not only of abolitionists, but also of free blacks who are more grounded in the vernacular tradition than equal to his own considerable skills in rhetorical literary construction.

My research addresses the problem that existing research inadequately considers the degree to which Douglass uses his awareness of the audience and employs rhetoric in …

Influential Factors Contributing To Compliance And/Or Non-Compliance With The Gluten-Free Diet For Celiac Disease Individuals, Jill Barnes

Masters Theses

Objective: The purpose of this study was to determine the influential factors of compliance and/or non-compliance with the gluten-free diet (GFD) for celiac disease (CD) individuals.

Methods: The data collection instrument was a self-developed survey using kwiksurveys.com. The data were collected via online survey distribution to CD support group facilitators in nine Midwestern states. CD support group facilitators assisted snowball sampling by distributing the online survey to other members of the support groups. Qualitative data from survey question 12 was reviewed for themes and patterns and discussed in a narrative form. Statistical analysis of the data was done using SPSS …

Beautiful Torment: Interpreting Dissonance And Text-Painting In Selected Sacred Choral Works Of William Byrd And Carlo Gesualdo, Janet M. Mccumber

Masters Theses

The end of the sixteenth century was filled with social, religious, and political turmoil; and yet, the musical atmosphere in England and Italy was conducive to new ideas in text-setting and chromatic inflection that had not been seen in previous eras. This thesis takes an interdisciplinary approach in looking at two late sixteenth-century composers, William Byrd and Carlo Gesualdo, and describes their personal and political sufferings and how these torments may have affected their compositional styles.

Brief explorations of England and Catholicism in the time of the Protestant Reformation, the Mannerist movement in the arts, the movement toward chromaticism in …

Soil Variability And Its Influence On Plant Performance, Jeremy R. Klass

Masters Theses

During recorded history, nearly all temperate deciduous forests in eastern North America have seen extensive agricultural land-use conversions. Persistent influences of agricultural disturbance continue to shape the diversity and composition of the plant community long after agriculture has ceased. While some measures of ecosystem functioning may recover relatively quickly from agricultural disturbance, other characteristics such as levels of organic matter, carbon, and phosphorus, may remain different from primary forests for much longer periods. The alteration of the original ecosystem due to agriculture practices has far reaching impacts on biotic and nutrient dynamics along with causing significant shifts in community composition …

Nanoporous High Surface Area Silicas With Chelating Groups For Heavy Metal Ion Adsorption From Aqueous Solution, Kothalawalage Nuwan Kothalawala

Masters Theses

Nanoporous high surface area silicas are an ideal substrate for the design of materials with useful properties via chemical surface modification. The adsorption of heavy metals for contaminated water detoxification is one potential application. In this work we have used three different kinds of silica substrates with varying pore structures; commercially available narrow pore and wide pore silica gels, as well as surfactant templated mesoporous SBA-15 exhibiting a relatively narrow pore size distribution. These silicas have each been subjected to post-synthesis modification with an organosilane consisting of ethylenediamine triacetic acid functionalities for chelation/adsorption of metal ions from aqueous solution. The …

The Undergraduate 2010, Saint Mary's College Of California

The Undergraduate Spectrum

No abstract provided.

Population Ecotoxicology Of The Common Snapping Turtle In Agriculturally Impacted Lotic Ecosystems, Derrick L. Douros

Masters Theses

Anthropogenic impacts on lotic systems, including pollutants, have had both direct and indirect negative effects on the aquatic habitats of the world. Goals of this study are: (1) Quantify atrazine, the atrazine metabolite diaminochlorotriazine (DACT), and glyphosate burdens in common snapping turtle (Chelydra serpentina) tissue from individuals collected within the Embarras River in Coles County, Illinois. (2) Quantify the atrazine, DACT, and glyphosate loads in water from the aquatic habitats in which common snapping turtles reside. (3) Quantify the relative abundance of all turtle species and movement patterns of common snapping turtles in this lotic ecosystem. Hoop nets and modified …

Plasticity Of Acquired Secondary Metabolites In Clathria Prolifera (Demospongia: Poecilosclerida): Putative Photoprotective Role Of Carotenoids In A Temperate Intertidal Sponge, Jonathan D. Dattelbaum, Drew Sieg, Malcolm Hill, Chris M. Manieri, Giles Thomson

Chemistry Faculty Publications

Several marine sponges sequester high concentrations of carotenoids in their tissues. The diversity of carotenoid compounds has been described in detail for a handful of species, but to date, little attention has been paid to natural variability in the concentration and constituency of carotenoid pools. Also lacking are experimental tests of some of the proposed adaptive benefits of carotenoids to the sponge. To address some of these deficits in our understanding of sponge ecology, we used a combination of analytic chemistry, field surveys, and manipulative experiments to determine what function these compounds might play. Attention was focused on the common, …

In Search Of Alternative Solutions: Can The State Of Origin Be Held Internationally Responsible For Investors' Human Rights Abuses That Are Not Attributable To It?, Vassilis Tzevelekos

Brooklyn Journal of International Law

No abstract provided.

"They Use It Like Candy": How The Prescription Of Psychotropic Drugs To State-Involved Children Violates International Law, Angela Olivia Burton

Brooklyn Journal of International Law

No abstract provided.

Genetically Modified Food And Informed Consumer Choice: Comparing U.S. And E.U. Labeling Laws, Valery Federici

Brooklyn Journal of International Law

No abstract provided.

Market Orientalism: Reassessing An Outdated Anti-Dumping Policy Towards The People's Republic Of China, Aaron Ansel

Brooklyn Journal of International Law

No abstract provided.

Owning Global Knowledge: The Rise Of Open Innovation And The Future Of Patent Law, Erin M. Shinneman

Brooklyn Journal of International Law

No abstract provided.

Colonial Cartographies, Postcolonial Borders, And Enduring Failures Of International Law: The Unending Wars Along The Afghanistan-Pakistan Frontier, Tayyab Mahmud

Brooklyn Journal of International Law

No abstract provided.

Talkin' Bout A Humane Revolution: New Standards For Farming Practices And How They Could Change International Trade As We Know It, Lesley Peterson

Brooklyn Journal of International Law

No abstract provided.

In The Hot House: Will Canada's Wto Challenge Slaughter U.S. Cool Regulations?, Carrie Ross

Brooklyn Journal of International Law

No abstract provided.