Digital Commons Network^™

The Regulation Of Nanomedicine: Will The Existing Regulatory Scheme Of The Fda Suffice?, Shanna Harris

Richmond Journal of Law & Technology

Nanotechnology is the science and technology of manipulating molecules and atoms at the molecular level to create devices with new molecular properties, organizations and functions.1 Devices such as new computers that are billions of times more powerful than any currently available2 and boxes the size of sugar cubes that can hold the entire content of the Library of Congress are examples of the power of nanotechnology.

Symbol Or Substance: An Empirical Assessment Of State Responses To Kelo, Andrew P. Morriss

Faculty Scholarship

The Kelo decision provoked considerable legislative activity as 46 states adopted legislation on eminent domain in its aftermath. Only about half adopted restrictions that were more than symbolic, however. This paper examines those responses using a logistic regression analysis and finds that all else equal: (1) states where legislatures were more constrained by tax and expenditure limits were less likely to adopt substantive restrictions; (2) a larger number of Republicans in the state legislature made a state more likely to adopt a substantive restriction; (3) overall Republican strength (as measured by gubinatorial [sic] elections) made states less likely …

Trademarks And Human Rights: Oil And Water - Or Chocolate And Peanut Butter, Megan M. Carpenter

Faculty Scholarship

In recent years, there has been a growing discourse at the intersection of intellectual property and human rights. Whether there is a direct connection between intellectual property, or the subjects of intellectual property, on the one hand, and human rights, on the other, has been the subject of lively debate. Most recently, the discussion has turned to the field of trademarks, which has prompted the question, Are trademarks human rights? In this article I seek to explore this question, and to consider directly whether there is a proper place for trademarks within the human rights framework-whether trademarks and human rights …

Change, Dependency, And Regime Plasticity In Offshore Financial Intermediation: The Saga Of The Netherlands Antilles, Craig M. Boise, Andrew P. Morriss

Faculty Scholarship

The legal regimes of offshore jurisdictions have historically differed in significant ways from those applicable in onshore jurisdictions. Inevitably, legal and financial professionals have seized upon these differences to develop strategies for reducing transactions costs. A prominent example of such cross-border arbitrage was the routing of Eurodollar loans through a small group of former Dutch island colonies in the Caribbean, a practice which peaked in the mid-1980s, when virtually every major U.S. corporation made interest payments to a Netherlands Antilles finance subsidiary. The "Antilles sandwich" strategy exploited the difference between high U.S. withholding tax rates that applied to interest payments …

Urban Gas Symposium Commentary, Frederic White

Faculty Scholarship

Undoubtedly, like any new discovery, the Barnett Shale, has brought wealth and prosperity to a considerable number of people. Great wealth, however, does not come without a price. Accordingly, new discoveries always lead to new controversies, new misunderstandings, and new disputes. The articles in this issue of the Law Review offer a diverse and well-rounded examination of some of these items and make an effort at offering some explanation and guidance for the future.

Comparison Of Trunk Muscle Forces And Spinal Loads Estimated By Two Biomechanical Models, N. Arjmand, D. Gagnon, André Plamondon, A. Shirazi-Adl, Christian Larivière

Études primaires

No abstract provided.

Effect Of Pelvic Stabilization And Hip Position On Trunk Extensor Activity During Back Extension Exercises On A Roman Chair, Rubens A. Da Silva, Christian Larivière, A. Bertrand Arsenault, Sylvie Nadeau, André Plamondon

Études primaires

OBJECTIVE: To assess the effect of pelvic stabilization and hip position on the electromyographic activity of trunk extensors during Roman chair exercise. A secondary objective was to compare genders. DESIGN: Repeated measures.

SUBJECTS: Eleven men and 11 women volunteers.

METHODS: Five trunk flexion-extension cycles for 3 Roman chair conditions: (i) pelvis unrestrained; (ii) pelvis restrained; and (iii) hip at 40 degrees flexion. Electromyographic signals were recorded on the back muscles, as well as on the gluteus maximus and biceps femoris. The percentage of electromyographic amplitude relative to the maximal activity was used to assess the level of muscular activation of …

Dna Profiling And Fourth Amendment Privacy, Daniel. Ohm

Harriet L Wilkes Honors College Theses 2003 - 2009

DNA profiling is a newly developed technique used by law enforcement agencies in the United States as a form of individual identification to prove whether a suspect is guilty. Due to the fact that it is a newly developed technology there is little legislation to regulate its proper uses and restrictions. Therefore restrictions are largely determined by court decisions as to whether DNA profiling violates constitutional rights. Current decisions in state and federal district courts tend to permit use of DNA profiling without a warrant. These decisions violate principles of privacy guaranteed by the US Constitution as interpreted in pre-DNA …

We Are Limestone Creek, Sara M. Stout

Harriet L Wilkes Honors College Theses 2003 - 2009

Limestone Creek is an unincorporated community existing within the planning and zoning boundary lines of Jupiter, Florida. Contrasting the economically flush and rapidly developing surrounding municipality of Jupiter, Limestone Creek is a predominantly African American community with an apparent economic gap that leaves the community untouched by development. This thesis project attempts to capture the voices of Limestone Creek and Jupiter residents pertaining to their accounts with an unincorporated area surrounded by a much wealthier municipality. Interviews were conducted with the residents of the community, Palm Beach County and the Town of Jupiter residents and officials, in an effort to …

Centrosome Recruitment, Erik. Raborn

Harriet L Wilkes Honors College Theses 2003 - 2009

The centrosome is a dynamic and highly active organelle within the cell. It plays a pivotal role in mitosis driving several of the physical changes that are taking place. The centrosome self-replicates before mitosis in order to set up two spindle poles on opposite sides of the cell. This leads to the creation of a mother and daughter centrosomes within a cell that have distinct components. This project will examine the recruitment of proteins to the centrosome as a cell progresses through the cell cycle. The proteins examined are (Sd(B-tubulin, (Sf(B-tubulin, Nek 2, Centrin2, p150Glued, EB-1, and dynein intermediate chain. …

Manipulation Of Normal Cells To Produce A Cancer-Like Mitotic Phenotype, Christina. Luffman

Harriet L Wilkes Honors College Theses 2003 - 2009

Most tumors contain multiple karyotypes due to genomic instability gained through chromosomal segregational defects. The variability of genomic changes within a population makes it difficult to study specific processes without the existence of confounding mutations. My project is to create a model system for observation of mitotic defects, specifically multipolar spindles, in a normal cell line, where the genome is intact. Induction of centrosome amplification is required for formation of multipolar spindles. Treatments with colcemid showed a 10% increase in abnormal centrosome numbers over control. However, treatment with hydroxyurea and transfection of hMPSl showed little increase. Extra centrosomes are insufficient …

Analyzing The Growth Of Protestantism, Amanda. Hoogkamp

Harriet L Wilkes Honors College Theses 2003 - 2009

There are several competing theoretical explanations for why Pentecostal Protestantism is growing rapidly in Latin America including affinities with the indigenous religions of the region, a recent increase in the supply of Pentecostalism due to missionary movements, a reduction in government regulation of religion, social anomie theory, and the pull of economic upward mobility through conversion. This study analyses the growth of Pentecostal Protestantism in the case of Mexico, utilizing state by state comparative data measuring these variables. While higher percentages of indigenous residents are correlated significantly with Pentecostal growth, government regulation and supply are less so. Social anomie and …

Correlation Between Specific Carcinogenic Chemicals And Specific Mitotic Defects And The Restorative Role Of Antioxidants, Travis. Yates

Harriet L Wilkes Honors College Theses 2003 - 2009

The progression of cancerous cells towards a more aggressive tumor can be linked to external elements called carcinogens. The goal of this project is to examine the correlation between exposure to specific carcinogens and an increase of mitotic defects. These defects can manifest as lagging chromosomes, multipolar spindles, and anaphase bridges. Some of these instabilities are associated with the formation of reactive oxygen species (ROS), which are known to damage DNA. The potential for damage to the genome can be averted via antioxidants. Using the oral cancer cell line UPCI:SCC103, we established a baseline for the mitotic defects in the …

Consequences Of Conditioned Democracy Promotion By The United States In Latin America, Kelly. Walsh

Harriet L Wilkes Honors College Theses 2003 - 2009

Democracy promotion is an important tenet of United States foreign policy. However, U.S. democracy promotion efforts are conditioned by geopolitical concerns, economic goals, and security interests. This thesis analyzes the impact of U.S. foreign policy in Chile, Colombia, El Salvador and Nicaragua. Evidence from these cases suggests that United States foreign policy has contributed to the growth of unhealthy or pseudo-democracies in Latin America because frequently the policy reinforces the political and economic power of entrenched elites or the military. These groups, whose interests more closely align with U.S interests, are often uncommitted to supporting policy that promotes human rights …

Sentinels Of Liberty, Robert Wicks

Harriet L Wilkes Honors College Theses 2003 - 2009

The Marvel character Captain America was created in 1941 as an unabashed, patriotic icon who was meant to inspire Americans in the face of war. At the end of World War II, however, American identity underwent a split between diplomatic "prophetic realism" and aggressive "zealous nationalism." The inherent dilemma for Captain America quickly became which side of the American psyche he was to represent. Marvel has dealt with the problem of representation by allowing the original Captain America to be a prophetic realist, while introducing "doubles" of Captain America who act as zealous nationalists. In each era of Captain America's …

Satan's Imprisoning Words, Victoria. Ryan

Harriet L Wilkes Honors College Theses 2003 - 2009

Through a critique of Satan's misuse of language, John Milton's Paradise Lost makes the greater argument that language should coincide with God's creation narrative. The poem proposes a theory of how language should be used: to connect the mutable world of humans to the immutable world of God. I propose that Milton uses Satan to portray both a fear and a faith in the power of language. Satan makes language the accomplice to his sin, attempting to use language, which has the power of creating a world that seems true, to replace God's Truth. Milton's poem neither solely endorses the …

Living Presence" And The "Ideal Character", Margaret Taylor

Harriet L Wilkes Honors College Theses 2003 - 2009

In my thesis I will argue that the source of the major conflict in Jude the Obscure - the traumatic relationship between Sue and Jude - is Jude's viewing of his cousin's photograph early in the novel. Because of his tendency to idealize the individuals around him, Jude projects a desired image onto a photograph of Sue before meeting her in real life. This projection takes on an aspect of reality for Jude which he can not escape, despite Sue's efforts to disillusion him and introduce him to her actual self. Since his projection starkly contrasts to Sue's actual being, …

Before And After Nagpra, Laura. Ray

Harriet L Wilkes Honors College Theses 2003 - 2009

The Native American Graves Protection and Repatriation Act (NAGPRA) was approved by Congress on November 16, 1990 after years of American Indian lobbying due to the unfair treatment of American Indian remains. Since the enactment of NAGPRA there have been multiple complaints from the archaeological community that the way in which they conduct their jobs has been severely limited by the implementation of NAGPRA. In this study I compare data from the Secretary's Report to Congress questionnaire, conducted by the National Park Service's Federal Archaeology Program, to determine whether NAGPRA has caused an increase or decrease in the amount of …

Caught Red-Handed, But Not Guilty, Katherine L. Mockler

Harriet L Wilkes Honors College Theses 2003 - 2009

There is a debate among scholars regarding how courts should judge defendants caught in government decoy and sting operations. As a retributivist, I believe we should only punish those who are culpable. Following this assumption, I argue that courts should punish entrapped people if they are culpable and that the subjective test, which holds that a defendant is culpable if he was predisposed to commit the crime, should be the standard by which courts judge defendants who claim entrapment. The objective test, which focuses on the propriety of the government conduct, fails to accurately assess culpability because, under this test, …

Activism Of The Catholic Church On Immigrants' Rights In The United States, Sandra Lazo De La Vega

Harriet L Wilkes Honors College Theses 2003 - 2009

This paper tests the religious economy model for predicting Church behavior which predicts that religious firms will become more politically active on behalf of potential members in areas where competition for those members is most fierce. An analysis of data from a survey of 106 U.S. Catholic dioceses and archdioceses on outreach to Hispanic immigrants does not support this hypothesis. Religious competition and Church activism on immigration issues did not correlate. Rather, demand for services (measured as Hispanic presence within each diocese) was a better predictor of Church activism on immigration issues. This finding suggests that the "inelastic demand" assumption …

Construction Of Mitochondrion-Targeted Telomerase For Analysis In Saccharomyces Cerevisiae, Ricardo. Martin

Harriet L Wilkes Honors College Theses 2003 - 2009

Telomerase is associated with telomere production and nDNA protection. However, studies by Santos et al. have demonstrated that human telomerase has a mitochondrial entry sequence and in the presence of hydrogen peroxide it has been found inside the mitochondrion and may cause mitochondrial DNA mutations. Saccharomyces cerevisiae contains telomerase, but it does not have the mitochondrial entry sequence. To determine if the presence of telomerase in the mitochondria can induce mutations an experiment was developed in which a mitochondrion entry sequence would be fused to the S. cerevisiae telomerase enzyme. This fusion could then be screened in S. cerevisiae with …

Help Or Hype?, Kathryn Klaas

Harriet L Wilkes Honors College Theses 2003 - 2009

International development literature suggests that Internet marketing has the potential to play an important role in rural development. Despite the abundant theoretical support for incorporating Internet marketing into development strategies, there is little empirical evidence regarding whether Internet marketing actually generates development. This thesis helps fill this gap in the literature by investigating whether one Internet marketing application associated with development, competitive-online auctions (COAs), contributes to growth and poverty reduction. An analysis of price premiums earned in Latin American specialty coffee auctions and interviews with participating coffee farmers suggest that this application's strength lies in its ability to catalyze development; …

Dynactin Is A Processivity Factor For Dynein In Vivo, Edward. Fulton

Harriet L Wilkes Honors College Theses 2003 - 2009

Dynein is a motor protein responsible for microtubule-based minus-end directed trafficking in eukaryotic cells. Dynactin is a protein complex involved in mitosis, embryonic development, intracellular trafficking and anchoring microtubules at the centrosome. While dynactin is widely recognized to improve the array of cargo with which dynein can associate, there has been some dispute over whether dynactin, which binds both dynein and microtubules, improves the distance that dynein can travel processively in the act of cargo trafficking before it dissociates from its microtubule. In this study, we compare movement parameters of wild type dynein-based vesicle movements with movements in cells where …

Celebration Of Uncertainty Through Gothic Moments In Emily Brontèe's Wuthering Heights, Kimberly. Copeland

Harriet L Wilkes Honors College Theses 2003 - 2009

While critics have argued that the Gothic moments in Emily Brontèe's Wuthering Heights merely illuminate the psyches of her characters, I show that these moments allow Brontèe to reveal a unique tension and overflow of emotion that arises between her two main protagonists. Blurring the lines between fantasy and reality, these displays --scenes of ghostly hauntings, bloody violence, and excessive emotion--create a desirable uncertainty about the limits of life and love in this novel. This uncertainty constitutes an escape from and an alternative to the conventional romantic relationship prescribed by social and narrative standards in which two people fall in …

Merely To Officiate Light", Kathryn H. Cruikshank

Harriet L Wilkes Honors College Theses 2003 - 2009

This thesis considers the role and function of God the Son within the anti-Trinitarian system John Milton envisions in his epic poem, Paradise Lost. In the poem, God the Father frequently acts independently of His Son, and the divine attributes that traditionally describe the Son, including His timelessness, no longer apply to the character Milton constructs. Despite this apparent degradation, Milton still elevates the Son and considers Him to be a character worthy of our respect. To account for this seeming paradox, I propose a reading of Paradise Lost that does not dismiss Milton's heretical belief in a subjected Son, …

Old Enough To Kill ; Too Young To Die?, Kristen. Chase

Harriet L Wilkes Honors College Theses 2003 - 2009

In 2005, the United States Supreme Court found the execution of juvenile offenders to be unconstitutional, based in part on a "national consensus" against the death penalty for juveniles. The purpose of this project was to demonstrate the flaws in existing methods of measuring public opinion and to determine the correlation between the age of an offender and the sentencing recommendation received. It was the hypothesis of my project that there would not be a statistically significant correlation between the offender's age and sentencing recommendation. To test this hypothesis, I asked 156 Florida Atlantic University students. This method of analysis …

Investigation Of Talin Head-Tail Interactions, Amber. Butyn

Harriet L Wilkes Honors College Theses 2003 - 2009

Talin is a ubiquitous, high-molecular-weight, flexible protein that plays a critical role in focal adhesions by activating, as well as connecting, integrins to the actin cytoskeleton. Talin's inactive auto-inhibitory state is speculated to be one of its modes of regulation inside the cell and is achieved through its head-tail interactions. In order to decipher the stability of this interaction, the head domain (residues 206-405) was cloned into a modified pET28m vector while the tail domains (residues 1654-2344 and 2225-2344) were cloned into the pET32a vector to obtain octa-histidine tagged and un-tagged peptide, respectively. Neither co-expression nor pull-down using the His-tagged …

Pelvic Stabilization And Semisitting Position Increase The Specificity Of Back Exercises, Rubens A. Da Silva, Christian Larivière, A. Bertrand Arsenault, Sylvie Nadeau, André Plamondon

Études primaires

No abstract provided.

Trunk Response Analysis Under Sudden Forward Perturbations Using A Kinematics-Driven Model, B. Bazrgari, A. Shirazi-Adl, Christian Larivière

Études primaires

No abstract provided.

Paraprofessionals Who Work With Elementary Grade Students With Significant Disabilities In Inclusive Settings, Regina Moreno

Dissertations and Theses

The use of paraprofessional services is an established and crucial aspect in the pursuit of a free and appropriate public education for students with disabilities. Paraprofessionals are often the primary providers of instruction for students with severe disabilities yet are the least trained instructional personnel in schools. Identified competencies and necessary training content for paraprofessionals who serve students with severe disabilities are nearly absent in the professional literature.

This study extended the current literature regarding paraprofessionals who serve students with disabilities in public schools by focusing specifically on those paraprofessionals who serve students with severe disabilities in inclusive general education …