Digital Commons Network^™

The Functioning Of Global Fit Statistics In Latent Growth Curve Modeling, Kathryn K. Deroche

Dissertations

No abstract provided.

The Existence Of Implicit Racial Bias In Nursing Faculty, Kathleen A. Fitzsimmons

Dissertations

No abstract provided.

Sensitivity Comparisons And Average Run Lengths Of The Mewms And Mewmv Control Charts Using Individual Observations With Singular Mean Shifts And Variance Changes, Chad Edgar Eshelman

Dissertations

No abstract provided.

A Comparison Study Of Sponsorship Effectiveness Between On-Site And Web-Based Sponsorship Activities, Issadee Kutintara

Dissertations

Virtually no evidence exists that current sponsorship activities on sporting event Web sites enable corporations to achieve sponsorship objectives including, but not limited to, increasing sales, improving image, or increasing awareness. The purpose of this study was to determine if significant differences of sponsorship effectiveness measures (brand awareness, attitude toward sponsorship, and purchase intentions) existed among a sample of Generation Y participants exposed to various sponsorship activities (on-site, online, and both on-site and online). The study surveyed 228 participants (112 on-site fans, 56 online fans, and 60 both on-site and online fans) exposed to the ESPN Winter X Games 13. …

Voices Of Striving Elementary Readers: An Exploration Of The Enhancement Of Struggling Reader Research Through Portraiture Methodology, Roland Kerry Schendel

Dissertations

This investigation was conducted to determine the value of using self-reports to elicit participant views of their reading struggles and to explore the potential benefits of using portraiture methodology as a means for illuminating the goodness inherent to struggling reader experiences in school. Three fourth grade participants were purposefully selected from one public and two charter elementary schools. Approximately three hours of interviews and 20 hours of observations were completed to collect data from each student over a 20 week period. With the participating students' teachers, approximately two hours of interview data were collected. Artifact gathering and the researcher journal …

An Information Prescription For Prescription Drug Regulation, Anita Bernstein, Joseph Bernstein

Faculty Scholarship

No abstract provided.

Improved Hydrogeophysical Parameter Estimation From Empirical Mode Decomposition Processed Ground Penetrating Radar Data, Adrian Addison, Bradley M. Battista, Camelia C. Knapp

Faculty Publications

Various techniques have been designed to maximize the use of ground penetrating radar (GPR) as an exploration tool. Improvements in signal processing are expected to further facilitate the accuracy of parameters derived from using GPR in certain geologic environments. Common-offset GPR data were collected at the Marine Corps Air Station (MCAS) in Beaufort, South Carolina, and dielectric constants were calculated following the application of the empirical mode decomposition (EMD) for dewowing GPR traces. Conventional signal processing is applied to the GPR traces to provide hydrogeophysical parameter estimates such as volumetric water content, porosity, and hydraulic conductivity. The results are validated …

Full Issue 4.3

Genocide Studies and Prevention: An International Journal

No abstract provided.

The International Criminal Court, The Security Council, And The Politics Of Impunity In Darfur, Victor Peskin

Genocide Studies and Prevention: An International Journal

This article analyzes the political challenges confronting the International Crimi- nal Court (ICC) in its efforts to bring war crimes suspects to trial in connection with mass atrocities committed in the Darfur region of Sudan. It chronicles and ex- amines the battles over cooperation between the ICC and the defiant Sudanese gov- ernment that have forestalled the handover of suspects such as Sudanese president Omar Hassan al-Bashir. It also seeks to explain why the Security Council, in its ambivalence toward the ICC, has not vigorously pressed Sudan to fulfill its legal obligation to cooperate.

Book Review: Samuel Totten And Eric Markusen, Eds., Genocide In Darfur: Investigating The Atrocities In The Sudan, Justyna Klaczany

Genocide Studies and Prevention: An International Journal

Edited by the two prominent genocide scholars Samuel Totten and Eric Markusen, Genocide in Darfur: Investigating the Atrocities in the Sudan is an outstanding collec- tion of essays that describes in great detail the genesis, design, implementation, re- sults, and ramifications of the Darfur Atrocities Documentation Project (ADP). What makes this work significant is the fact that the essays are written not only by many noted scholars, US government and non-governmental organization officials, but also by the ADP designers and investigators. The perspectives of the latter is extremely valuable, since they were the people who conducted the interviews with the …

The New Concept Of Loyalty In Corporate Law, Andrew S. Gold

Faculty Scholarship

No abstract provided.

No Association Of Obesity And Type 2 Diabetes Mellitus Related Genetic Variants With Colon Cancer, Cheryl L. Thompson, Sarah J. Plummer, Thomas C. Tucker, Graham Casey, Li Li

Markey Cancer Center Faculty Publications

Background: Obesity and type 2 diabetes mellitus (T2D) are known risk factors for colon cancer. Recent reports from a number of genome wide association studies (GWAS) have identified several single nucleotide polymorphisms (SNPs) associated with obesity and T2D. Here we tested the hypothesis that these SNPs may also be associated with risk of colon cancer.

Methods: We genotyped nine SNPs reported in GWAS of obesity and/or T2D, including SNPs in HHEX, KCNJ11, SLC30A8, FTO, CDKN2, CDKAL1, TCF2, and the rs9300039 SNP in an intergenic region, in 561 colon cancer cases and 721 population controls.

Results: None of these SNPs were …

Discovery And Validation Of New Regulatory Rna Elements In Chlamydia Trachomatis, Yasser Mohammed Elsayed Metwally Abdelrahman

Theses and Dissertations (ETD)

Chlamydia trachomatis is an obligate intracellular bacterium that exhibits a unique biphasic developmental cycle that can be disrupted by growth in the presence of IFN-g and b-lactams, giving rise to an abnormal growth state termed persistence. Relatively little is known about the regulatory mechanisms that control temporal gene expression during the developmental cycle or the control of persistence and reactivation. Here we have examined the expression of a newly defined family of non-coding RNAs (ncRNAs) that are differentially expressed during the developmental cycle and the induction of persistence and reactivation (Using IFNγ and Carbenicillin). Non-coding RNAs were initially identified using …

Chitosan/Ellagic Acid Composite Materials For Local Cancer Therapy, Sung Woo Kim

Theses and Dissertations (ETD)

Current advances in the drug delivery have improved the therapeutic efficacy of the drug and minimized risks of side effects associated with toxicity of the drug. Implantable polymeric delivery system has gained increasing attentions for controlled drug release and localized treatments. In comparison to conventional chemotherapy, polymeric delivery systems are implantable at a local targeted site and biodegradable after a sufficient therapeutic span. The objectives of this project were to fabricate and characterize an implantable polymeric vehicle for a local chemotherapy and investigate its biological properties against cancer cells including human WM115 melanoma, human U87 glioblastoma, and rat C6 glioma …

Identification Of The Downstream Effector Genes Involved In Hoxb4-Induced Expansion Of Hematopoietic Progenitor Cells, Jie Jiang

Theses and Dissertations (ETD)

Overexpression of HOXB4, a member of Homeobox transcription factor family, promotes expansion of hematopoietic stem and progenitor cells bothin vivo and in vitro. However, the molecular mechanisms underlying this effect are not well understood. In order to identify direct target genes of HOXB4 in primary murine hematopoietice progenitor cells, we induced HOXB4 function in lineage-negative, murine bone marrow cells, using a tamoxifen-inducibleHOXB4-ER^T2fusion protein. Seventy seven genes with differentially changed expression in early response to HOXB4 have been identified as candidate target genes. Among them, we show that Hemogen (Hemgn), encoding a nuclear protein specifically …

Contribution Of The Membrane-Proximal Region Of The Vesicular Stomatitis Virus Glycoprotein To Host Cell Entry And Membrane Fusion, Elizabeth Lane Matheny

Theses and Dissertations (ETD)

Vesicular stomatitis virus (VSV) is an enveloped, nonsegmented, negative-sense, RNA virus belonging to the Rhabdoviridae family. VSV is considered the prototypic Rhabdovirus due to its simple genetic organization, broad host cell tropism, and ability to be easily grown in cell culture. Therefore, VSV has been used as the prototype to study viral entry, transcription, replication, and assembly. Viral entry, a critical step in the lifecycle of the virus, is mediated by the outer surface protein, G and will be the focus of this dissertation.

We hypothesize that the highly conserved residues in the membrane-proximal region of VSV G protein are …

Physical And Functional Coupling Of Cftr And Pde3a, Himabindu Penmatsa

Theses and Dissertations (ETD)

Formation of multiple-protein macromolecular complexes at specialized subcellular microdomains increases the specificity and efficiency of signaling in cells. In this study, we demonstrated that phosphodiesterase type 3A (PDE3A) is physically and functionally coupled to cystic fibrosis transmembrane conductance regulator (CFTR). PDE3A inhibition increases cyclic adenosine 3′, 5′-monophosphate (cAMP) levels in a compartmentalized manner at the plasma membrane, which potentiates CFTR channel function and further clusters PDE3A and CFTR into microdomains. Actin skeleton disruption reduces PDE3A-CFTR interaction; segregates PDE3A from its interacting partners thus compromise the integrity of the macromolecular complex. Consequently, PDE3A inhibition no longer activates CFTR channel function in …

The Use Of Classroom Walk-Through Observations As A Strategy For Improving Teaching And Learning: Teacher Perspective, Leslie Mcentire, Mark Weller, Thomas R. Sorensen

Dissertations

The purpose of this study was to investigate the use of classroom walk-through observations and their effect on Communication Arts and Mathematics Missouri Assessment Program (MAP) scores, summer school placement, discipline referrals, and retention. This study was conducted in three Midwestern Middle Schools. This study focused on classroom walk-through observations. If the principal increased the number of classroom walk-through observations, would it have an impact on Communication Arts and Mathematics MAP scores, summer school placement, discipline referrals and retention? This study will attempt to determine if classroom walk-through observations had an impact on Communication Arts MAP scores, Mathematics MAP scores, …

What Makes Strategy Making Across The Sales-Marketing Interface More Successful?, Avinash Malshe, Ravipreet S. Sohi

Department of Marketing: Faculty Publications

Extant research on marketing strategy making (MSM) lacks process-based theoretical frameworks that elucidate how marketing strategies are made when sales and marketing functions are involved in the process. Using a grounded theory approach and data collected from (a) 58 depth interviews with sales and marketing professionals and (b) a focus group with 11 marketing professionals, we propose that MSM within the sales-marketing interface is a three-stage, multifaceted process that consists of Groundwork, Transfer and Follow-up stages. Our process-based model explicates the specific activities at each stage that are needed to develop and execute marketing strategies successfully, the sequence in which …

A Qualitative Study Of High-Reputation Plant Managers: Political Skill And Successful Outcomes, Anne D. Smith, Donde Ashmos Plowman, Dennis Duchon, Amber M. Quinn

Department of Management: Faculty Publications

There has been little systematic study of what plant managers actually do on a day-to-day basis that accounts for their success in achieving organizational outcomes. In our field interviews and observations of high-reputation plant managers from 11 manufacturing plants, we found that effective political skill enabled them to influence subordinates in ways that contributed positively to organizational outcomes. Political skill is an interpersonal style that combines social astuteness with the ability to relate well, and otherwise demonstrate situationally appropriate behavior in an engaging way that inspires confidence, trust, and genuiness [Ferris, G.R., Perrewé, P.L., Anthony, W.P., Gilmore, D.C., 2000. Political …

Steinernema Diaprepesi (Nematoda: Steinernematidae): Its Occurrence In Western Mexico And Susceptibility Of Engorded Cattle Ticks Boophilus Microplus (Acari: Ixodidae), Jaime Molina-Ochoa, Khuong B. Nguyen, Martín González-Ramírez, Miguel Guadalupe Quintana-Moreno, Roberto Lezama-Gutiérrez, John E. Foster

Department of Entomology: Faculty Publications

Entomopathogenic nematodes (EPN) belong to the families Steinernematidae and Heterorhabditidae. They infect a wide range of insect hosts and are used to control numerous species of soil borne insect pests (Grewal 2002). We identified EPN genera based on the color of cadavers of the wax moth, Galleria mellonella L., in which Heterorhabditis and Steinernema, produce red and tan colors, respectively, according to Woodring & Kaya (1988). We obtained an isolate of an EPN from sandy loam soil with the Galleria technique (Bedding & Akhurst, 1975) from grasslands in the Campus Tecomán of the Universidad de Colima, and we designated it …

Using Electronic Faculty Course Portfolios To Showcase Classroom Practices And Student Learning, Paul Savory, Amy M. Goodburn

Department of Industrial and Management Systems Engineering: Faculty Publications

Faculty course portfolios are a valuable medium for documenting and making visible the serious intellectual work of teaching. Developing a faculty course portfolio follows the same process one uses to explore a research question. Faculty members inquire, analyze, and document their teaching practices and the resulting student learning and then make the results accessible for use, review, and assessment by one’s peers. In this article, we introduce four types of electronic course portfolios that sponsor different forms of inquiry into student learning. We highlight the major components of each type, offer advice in developing them, and share examples of each. …

Zhong Guo Gao Zhong Sheng Yin Jiu Zhuang Kuang Yan Jiu De Hui Gu [Review Of Studies Of Chinese High School Students’ Drinking Behavior], Ian Newman, Ling Qian, Jianguo Zhang, Jie Zhao, Ying Zhang

Department of Educational Psychology: Faculty Publications

No abstract provided.

Community Structure And Seasonal Dynamics Of Dactylogyrus Spp. (Monogenea) On The Fathead Minnow (Pimephales Promelas) From The Salt Valley Watershed, Lancaster County, Nebraska, Alaine Knipes, John J. Janovy Jr.

John J. Janovy, Jr. Publications

The gill monogene communities of Pimephales promelas (fathead minnow) in three distinct sites on converging streams were investigated from 2004 to 2006 in three different seasons. Thirty collections of P. promelas were made in southeastern Nebraska along three converging tributaries: Elk Creek (40.88534°N, 96.83366°W), West Oak Creek (40.9082°N, 96.81432°W), and Oak Creek (40.91402°N, 96.770583°W), Lancaster County, Nebraska. In all, 103 P. promelas were collected from Elk Creek, 115 from West Oak Creek, and 78 from Oak Creek and examined for gill monogenes. Among the P. promelas collected, 93.5% were infected with up to three species of Dactylogyrus, including Dactylogyrus …

Modeling Of Metal-Ferroelectric-Insulator-Semiconductor Structures Based On Langmuir–Blodgett Copolymer Films, Timothy J. Reece, Stephen Ducharme

Stephen Ducharme Publications

Among the ferroelectric thin films used in field-effect transistor devices; the ferroelectric copolymer of polyvinylidene fluoride PVDF –CH2–CF2–, with trifluoroethylene TrFE –CHF–CF2–, has distinct advantages, including low dielectric constant, low processing temperature, low cost, and compatibility with organic semiconductors. The operation of a metal-ferroelectric insulatorsemiconductor structure with PVDF-TrFE as the ferroelectric layer was analyzed and optimized by numerical solution of the Miller and McWhorter model. A model device consisting of 20 nm PVDF/TrFE on a 10-nm-thick high-k dielectric buffer exhibits a memory window of 5 V with an operating voltage of 15 V. The operating voltage can be reduced to …

Molecular Strain Typing Of Mycobacterium Tuberculosis Isolates To Detect Cross-Contamination Events. Proposed Modifications To Prevent Its Recurrence., Sahal A. Al-Hajoj

Saudi Medical Journal

OBJECTIVES: To investigate possible cross-contamination events of Mycobacterium tuberculosis cultures, and also to shed light on cross-contamination problems in our laboratories. METHODS: At the TB Research Unit in the Department of Comparative Medicine Research Centre of King Faisal Specialist Hospital and Research Centre, Riyadh, Kingdom of Saudi Arabia, we received 22 TB isolates sub-cultured on Lowenstein-Jensen media from a local laboratory in Riyadh on 1st July 2005. We finger printed all 22 isolates in question using a polymerase chain reaction-based spoligotype molecular technique. The epidemiological and clinical data were reviewed. RESULTS: All 22 cases had been proven to be cross-contaminated …

Effectiveness Of Ankaferd Blood Stopper In The Topical Control Of Active Bleeding Due To Cutaneous-Subcutaneous Incisions., Behcet Al, Cuma Yildirim, Murat Cavdar, Suat Zengin, Hasan Buyukaslan, Mehmet E. Kalender

Saudi Medical Journal

OBJECTIVES: To assess the effectiveness of Ankaferd blood stopper (ABS) in the topical control of bleeding due to cutaneous/subcutaneous incisions. METHODS: We included in this study, 69 patients with cancer that were admitted for port insertion to the Emergency Department of Gaziantep University Hospital, Gaziantep, Turkey, between May and July 2008. We used the wet compress form of ABS in 37 patients (group I), and regular dry sterile sponges in 32 patients (group II), to stop the bleeding that occurs during the clinically indicated vascular port insertion in patients with cancer. The success rate in terms of bleeding control, time …

The Use Of Sweat Chloride Test For Screening Cystic Fibrosis Among Malnourished Children Suffering From Frequent Respiratory Infections., Nazih K. Abu-Alshiekh, Sameer M. Kofahi, Zuhair M. Nusair

Saudi Medical Journal

OBJECTIVES: To establish a reliable cost-effective screening criterion for cystic fibrosis (CF) among underweight children suffering from frequent chest infections using the sweat chloride test (SCT). METHODS: In a cross-sectional study, 145 children with frequent chest infections were seen in the Pediatric Department at Prince Rashed Bin Al-Hassan Hospital, Irbid, Jordan, between January and December 2008. Their age ranged from 2-12 years (87 males and 58 females). We obtained 11 children with positive polymerase chain reaction (PCR) for CF from hospital laboratory records, and 134 had no confirmed CF. Nutritional anthropometric assessment of weight-for-age and height-for-age based on the Centers …

A Balanced Anesthesia With Dexmedetomidine Decreases Postoperative Nausea And Vomiting After Laparoscopic Surgery., Islam M. Massad, Wafa A. Mohsen, Asma S. Basha, Khaled R. Al-Zaben, Mahmoud M. Al-Mustafa, Subhi M. Alghanem

Saudi Medical Journal

OBJECTIVES: To evaluate the effect of adding dexmedetomidine to a balanced anesthetic technique on postoperative nausea and vomiting after laparoscopic gynecological surgeries. METHODS: A prospective double-blind randomized study was designed at Jordan University Hospital, Amman, Jordan between December 2008 and February 2009. Eighty-one female patients in their child-bearing age (17-48 years); American Society of Anesthesiologists (ASA) clinical status I, who were scheduled for elective diagnostic laparoscopic surgeries under general anesthesia were divided into 2 groups. Group D (n=42) received dexmedetomidine infusion, while group P (n=39) received 0.9% sodium chloride infusion along with the balanced anesthesia. The incidence of early (up …

Is There A Relationship Between Body Mass Index And Serum Vitamin D Levels?, Abdulmohsen H. Al-Elq, Mir Sadat-Ali, Haifa A. Al-Turki, Fathma A. Al-Mulhim, Amein K. Al-Ali

Saudi Medical Journal

OBJECTIVES: To evaluate the relationship between vitamin D level and body mass index (BMI) among Saudi Arabian citizens. METHODS: Four hundred healthy individuals aged > or =25 years (200 males and 200 females) were included in this cross-sectional study. Subjects were recruited in the period between 1st February 2008 and 31st May 2008 from the medical staff and employees of King Fahd Hospital of the University, Al-Khobar, Kingdom of Saudi Arabia, and from patients attending the endocrinology, orthopedic, and infertility clinics at the same hospital. Clinical evaluation was carried out, and BMI was calculated. Serum 25 hydroxy vitamin D (25OHD), in …