Digital Commons Network^™

Psychiatrists' And Psychiatric Aprns' Views Of The Adolescent Mental Health Nurse's Role In The Inpatient Setting, Dana Lehner

Honors Scholar Theses

Current perceptions about nurses’ roles and responsibilities are examined in this study, specifically relating to adolescent inpatient MHNs. Psychiatrists and psychiatric advanced practice registered nurses (APRNs), who work with MHNs and have also published scholarly psychiatric articles, were contacted to request their participation in an anonymous survey hosted by SurveyMonkey.com. This research was conducted to examine the stereotypes that exist against nurses within the health care profession itself, as compared to the pre-existing stereotypes displayed by the media’s view of nurses. Due to investigator time constraints, only six subjects participated in the study. Analysis of survey responses revealed four overarching …

Time Series Observations Of Species Composition And Behavioral Interactions Of Fish At An Ocean Observatory Off The Coast Of Georgia, Amy E. Paquette

Honors Scholar Theses

The use of ocean observatories is expanding with the potential for collecting serial data with high temporal resolution at multiple sites within an ecosystem. Integration of underwater video cameras in observatory systems allow observation of vagile species and are useful tools for observing variations in behavior over time. In order to assess the utility of using video records for time series behavioral data I analyzed video records from an observatory site in the South Atlantic Bight (SAB) off the Coast of Georgia collected during the month of November in 2000, 2002 and 2004. Data were used to quantify annual variation …

The Role Of Raf Kinase Inhibitor Protein In Cell Motility, Kathryn Grive

Honors Scholar Theses

Raf Kinase Inhibitor Protein (RKIP) has been identified as a phosphatidylethanolamine-binding protein capable of inhibiting Raf-1 kinase, an enzyme significant in cell proliferation and cancer development. When properly functioning, RKIP can mediate the expression of Raf-1 kinase and help prevent uncontrolled cell division. RKIP also has suggested, but unclear, roles in spindle fiber formation during mitosis, regulation of apoptosis, and cell motility. The Fenteany laboratory in the Chemistry Department identified a new small molecule, named Locostatin, as a cell migration inhibitor in mammalian cells, with RKIP as its primary molecular target.

Dictyostelium discoideum possess two RKIP proteins, RKIP-A and RKIP-B. …

History Of Maltreatment And Psychiatric Impairment In Children In Outpatient Psychiatric Treatment, Kerry Gagnon

Honors Scholar Theses

There is increasing evidence that childhood victimization and attachment disruptions impact a child’s development. In this study, children and adolescents from an outpatient psychiatric clinic were assessed, measuring history of trauma, history of out-of-home placement, initial diagnoses, and CBCL internalizing and externalizing problem scores. Multiple regression analyses showed that both violent abuse trauma (physical/sexual abuse) and victim trauma (physical abuse/sexual abuse/witnessing domestic violence/witnessing community violence) are prevalent among patients with externalizing severity problems; concluding that diagnosis alone may not account for a history of victimization, but externalizing problem severity does. Overall, the study is consistent with past literature that it …

Intrinsic Ph-Sensitivity Of Cells In The Retrotrapezoid Nucleus: Possible Role Of Glia In Respiratory Drive, Nicole Edwards

Honors Scholar Theses

An increase in carbon dioxide (CO2) and protons (H+) are the primary signals for breathing. Cells that sense changes in CO2/H+ levels and increase breathing accordingly are located in a region of the caudal medulla oblongata called the retrotrapezoid nucleus (RTN). Specifically, select RTN neurons are intrinsically pH sensitive and send excitatory projections to the respiratory rhythm generator to drive breathing. Glial cells in the RTN are thought to contribute to this respiratory drive, possibly by releasing ATP in response to increases in CO2/H+ levels.

However, pH sensitivity of RTN glial cells has yet to be determined.

Therefore, the goal …

Head And Neck Embryology: An Overview Of Development, Growth And Defect In The Human Fetus, Allison Baylis

Honors Scholar Theses

The purpose of this research is to explore the growth and formation of the head and neck from embryological development through puberty in order to understand how this knowledge is necessary for the development of dental and medical treatments and procedures. This is a necessary aspect of the medical and dental school curriculum at the University of Connecticut Health Center Schools of Medicine and Dental Medicine that needs to be incorporated into the current study of embryology for first-year students. Working with Dr. Christine Niekrash, D.M.D, this paper will cover the embryology and growth of the head, face and oral …

Diagnosing The Prodromal State Of Alzheimer's Disease, Jennifer Bartkowiak

Honors Scholar Theses

Mild Cognitive Impairment- Amnestic Subtype (MCIa) is a putative prodromal stage of Alzheimer’s Disease (AD) characterized by focal deficits in episodic verbal memory. Less is known about relative deficits in visuospatial learning, although there is ample evidence indicating involvement of the hippocampus in visuospatial learning, as well as hippocampal degeneration in early AD. The aim of this study was to better characterize the components of working memory dysfunction in people with MCIa to increase the ability to reliably diagnose this disease. Fifty-six elderly adults diagnosed with MCIa and 94 healthy elderly completed a hidden maze learning task. Results indicated similar …

Characterizing The Role Of Phaeobacter In The Mortality Of The Squid, Euprymna Scolopes, Brian Shawn Wong Won

Honors Scholar Theses

The subject of our study is the Hawaiian bobtail squid, Euprymna scolopes, which is known for its model symbiotic relationship with the bioluminescent bacterium, Vibrio fischeri. The interactions between E. scolopes and V. fischeri provide an exemplary model of the biochemical and molecular dynamics of symbiosis since both members can be cultivated separately and V. fischeri can be genetically modified 1. However, in a laboratory setting, the mortality of embryonic E. scolopes can be a recurrent problem. In many of these fatalities, the egg cases display a pink-hued biofilm, and rosy pigmentation has also been noted in the deaths of …

Optimization Of Protein Expression Of Four Transcription Factors Using Chaperone Proteins, Kaitlin Wilson

Honors Scholar Theses

Embryonic stem cells are unique in their ability to grow indefinitely while maintaining both pluripotency and self-renewal capabilities. These stem cells could be the answer to solving many of the debilitating and devastating diseases suffered by humans. Recently, the use of human derived embryonic stem cells has been effective in animal models in the treatment of spinal cord injuries (Kierstead et al., 2005).

Although the study of embryonic stem cells has become increasingly popular in the last decade, there is still much research to be done to increase the expression of valuable embryonic proteins which will induce pluripotency in the …

Characterization Of A Hypothetical Protein Critical For The Symbiotic Interaction Of Aeromonas Veronii And Hirudo Verbana, Kaitlin Vaughan

Honors Scholar Theses

The digestive tract symbiosis of the medicinal leech, Hirudo verbana, is a model system for studying the genes required for microbial colonization of digestive tracts, as H. verbana has only two species of bacteria that dominate the crop microbiota, Aeromonas veronii and a Rikenella-like bacterium. Signature-tagged mutagenesis (STM) of the A.

veronii strain, HM21R, revealed genes required for the colonization of the digestive tract. One of these mutants, JG573, has an interrupted gene that is predicted to encode a hypothetical protein. The region flanking the transposon insertion of this mutant was sequenced by primer walking.

Comparison of the flanking DNA …

Behavioral Implications Of Knockout For The Dyslexia-Risk Gene Dcdc2 In Mice, Dongnhu Truong

Honors Scholar Theses

Several genetic linkage and epidemiological studies have provided strong evidence that DCDC2 is a candidate gene for developmental dyslexia, a disorder that impairs a person’s reading ability despite adequate intelligence, education, and socio-economic status. Studies investigating embryonic intra-ventricular RNA interference (RNAi) of Dcdc2, a rat homolog of the DCDC2 gene in humans, indicate disruptions in neuronal migration in the rat cortex during development. Interestingly, these anatomical anomalies are consistent with post mortem histological analysis of human dyslexic patients. Other rodent models of cortical developmental disruption have shown impairment in rapid auditory processing and learning maze tasks in affected subjects.

The …

Salivary Cortisol, Psychological Stress And Depressive Symptoms Among Patients Undergoing Colon Cancer Screenings, Allyson Reid

Honors Scholar Theses

As the second leading cause of cancer-related deaths in the United States, colon cancer has a high cure rate if detected early by a colonoscopy (U.S.

Cancer Statistics Working Group, 2007). However, more than 41 million at-risk Americans are not properly receiving colonoscopy screenings according to the recommendations of the Center for Disease Control. This study provides insight into the physiological and psychological benefits of the colonoscopy procedure over and above cancer detection and prevention. Thirty-six patients receiving colonoscopic screening at the University of Connecticut Health Center participated in this study. A questionnaire battery that assessed perceived stress, depressive symptoms, …

Contribution Of The Novel C-Terminal Domain To The Ribosome Binding Activities Of Virulence Regulator Bipa, Heeren Makanji

Honors Scholar Theses

Bacterial GTPases regulate many cell functions, including the stress response, signal recognition, protein synthesis, and cell differentiation, through a molecular switch that is activated and deactivated depending on their nucleotide bound state (1). A member of the translational family of bacterial GTPases along with LepA and EF-G, BipA is a 67 kD protein that is essential for virulence and the stress response. Crystal structures from the Robinson lab have shown a unique C-terminal domain on BipA that has been implicated in ribosome binding. Using N-terminal deletion constructs, we have shown that the C-terminal domain is necessary, but not sufficient, to …

Lost In Translation: Emotion And Expression Through Technology, Shaylyn Joy

Honors Scholar Theses

My Thesis study was designed to bring to topic certain issues involved with CMC (computer-mediated communication.) Often we are presented with confusing or misleading situations when it comes to expressing our emotions through technological means. It is important that we are aware of certain issues such as the use of emoticons, expressing sarcasm, and the ongoing trend of Internet slang. These various aspects can create confusion in CMC, leading to a loss in translation. My survey study was designed to probe deeper into these issues by asking general questions and by analyzing sample CMC scenarios.

Cooperation & Competition Between Navigation Systems In The Rat Brain: The Role Of The Hippocampus And Striatum During A Dissociative Maze Task, Benjamin Gruenbaum

Honors Scholar Theses

While many tend to think of memory systems in the brain as a single process, in reality several experiments have supported multiple dissociations of different forms of learning, such as spatial learning and response learning. In both humans and rats, the hippocampus has long been shown to be specialized in the storage of spatial and contextual memory whereas the striatum is associated with motor responses and habitual behaviors.

Previous studies have examined how damage to hippocampus or striatum has affected the acquisition of either a spatial or response navigation task. However even in a very familiar environment organisms must continuously …

Gay Parenthood And The Revolution Of The Modern Family: An Examination Of The Unique Barriers Confronting Gay Adoptive Parents, Nicholas Arntsen

Honors Scholar Theses

Abstract: In recent decades, the structure of the American family has been revolutionized to incorporate families of diverse and unconventional compositions. Gay and lesbian couples have undoubtedly played a crucial role in this revolution by establishing families through the tool of adoption. Eleven adoptive parents from the state of Connecticut were interviewed to better conceptualize the unique barriers gay couples encounter in the process adoption. Both the scholarly research and the interview data illustrate that although gay couples face enormous legal barriers, the majority of their hardship comes through social interactions. As a result, the cultural myths and legal restrictions …

Knockdown Of Kiaa0319 Reduces Dendritic Spine Density, Daniel Young Kim

Honors Scholar Theses

Developmental Dyslexia is a reading disorder that affects individuals that possess otherwise normal intelligence. Until the four candidate dyslexia susceptibility genes were discovered, the cause of cortical malformations found in post mortem dyslexic brains was unclear. Normal brain development is crucial for the proper wiring of the neural circuitry that allow an individual to perform cognitive tasks like reading. For years, familial and twin studies have suggested that there was a genetic basis to the causation of dyslexia. Kiaa0319 was among the candidate dyslexia susceptibility genes that were ascertained. KIAA0319 is located on Chromosome 6p22.2-22.3 and has been found to …

Fort Richardson Ordnance Detonations And The Harbor Porpoise: A Case Study In Marine Mammal Bioacoustics, Heather Heenehan

Honors Scholar Theses

Hearing is extremely important for cetaceans because it is their “principal sense” (Weilgart, 2007) thus the harbor porpoise and other marine animals are highly dependent on sound for survival. This is why we should care about the impact of noise on animals like the harbor porpoise. Since sound travels so well in water, an explosion, sonar, boat noise, etc. can affect a very large area and thus many different species of marine mammals. Although military actions such as low frequency sonar have made recent news, noise has been affecting cetaceans, especially beaked whales, since at least 1991 (Weilgart, 2007).

This …

A Replicon Trans-Packaging System Reveals The Requirement Of Nonstructural Proteins For The Assembly Of Bovine Viral Diarrhea Virus (Bvdv) Virion, Delin Liang, Limei Chen, Israrul H. Ansari, Laura H. V. G. Gil, Christina L. Topliff, Clayton L. Kelling, Ruben O. Donis

School of Veterinary and Biomedical Sciences: Faculty Publications

A selective trans-packaging system was developed to produce and isolate bovine viral diarrhea virus (BVDV) pseudo-particles with complementing reporter replicons and their packaging proteins expressed in trans with recombinant vaccinia virus. The encapsidation of replicon rNS3-5B was dependent not only on the in trans expression of structural proteins C, Erns, E1 and E2, but also the nonstructural proteins, p7 and contiguous precursor NS2-3-4A. Nonstructural p7, NS4B, NS5A or NS5B could be expressed in cis and in trans with precursor NS2-3-4A without significantly affecting virion assembly efficiency. NS2-3-4A was identified as an in trans functional precursor in virion assembly. BVDV …

University Of Richmond Commencement Exercises Program - 2009

Commencement Programs

University of Richmond Commencement Exercises Program, 2009. Including Conferring of Degrees to School of Arts and Sciences Graduate School: Master of Arts, and Master of Liberal Arts; The E. Claiborne Robins School of Business The Richard S. Reynolds Graduate School: Master of Accountancy, and Master of Business Administration; School of Arts & Sciences: Bachelor of Arts, and Bachelor of Science; The E. Claiborne Robins School of Business: Bachelor of Science in Business Administration; Jepson School of Leadership Studies: Bachelor of Arts.

Eight Is Enough, Naomi R. Cahn, Jennifer R. Collins

NULR Online

No abstract provided.

Turbulent Coherent Structures Near Coastal Capes, Marcello G. Magaldi

Open Access Dissertations

A numerical study aimed at investigating the conditions under which different flow regimes appear near coastal capes is presented. The impacts of the regimes are also quantified in terms of integral quantities like mixing, current transport and form drag. Idealized and realistic numerical simulations are run both in barotropically and baroclinically-driven systems. The realistic cases model the Western Adriatic Current (WAC) in the Adriatic Sea. In both cases, the turbulent state of the flow is controlled in first approximation by the Burger number, Bu. When a steady barotropic and geostrophic current impinges on a triangular idealized cape, vertical movements are …

Development And Applications Of Second-Order Turbulence Closures For Mixing In Overflows, Mehmet Ilicak

Open Access Dissertations

Mixing between overflows and ambient water masses is a crucial problem of deep-water formation in the down-welling branch of the meridional overturning circulation of the ocean. In this dissertation work, performance of second-order turbulence closures in reproducing mixing of overflows is investigated within both hydrostatic and non-hydrostatic models. First, a 2D non-hydrostatic model is developed to simulate the Red Sea overflow in the northern channel. The model results are compared to the Red Sea Outflow Experiment. It is found that the experiments without sub-grid scale models cannot reproduce the basic structure of the overflow. The k-ε model yields unrealistically thick …

A Human Security Population-Based Approach To Achieve Equity, Solidarity And Gender Sensitivity For The Population Living In Southwestern Bateyes Of The Dominican Republic, Eddy Nelson Perez

Open Access Dissertations

The present study was designed to contribute to the application of human security principles in vulnerable populations, using the Bateyes (sugar mill camps) from the Dominican Republic (DR) as a case study. Following the Robin Hood principle of using resources allocated for the identification and treatment of human immunodeficiency virus (HIV) as a base from which to build infrastructure for other health and human security needs, this project sought to reduce inequalities and promote equal rights in a vulnerable population living in isolated rural areas of the DR. The impact of a human security model versus non-intervention (standard of care) …

2009 May 9

Commencement Programs

No abstract provided.

Spring 2009 Commencement - The University Of Texas Of The Permian Basin, The University Of Texas Permian Basin

UTPB Commencement Programs

Spring 2009 Commencement - May 9, 2009

Doctor Of Medicine Commencement: May 9, 2009, University Of North Dakota

UND Commencement Programs

Doctor of Medicine Commencement program from May 9, 2009.

Commencement Program 2009 May Undergraduate, Gcsu Special Collections

Commencement Programs

No abstract provided.

2009 Commencement Program, Longwood University

Undergraduate Commencement Programs

Itinerary and list of graduates for 2009 commencement. Address given by Jerome Kersey

Spring Commencement [Program], May 9, 2009, University Of Northern Iowa

UNI Commencement Programs

The program of the commencement ceremonies, including a list of institutional leadership, a list of the departments by college, awards given at the ceremonies, and a list of undergraduate and graduate degree candidates.