Digital Commons Network^™

Frequency Of Tlr-2, 4, 9 And Cd14 Polymorphisms In Aggressive Periodontitis Population In African-Americans, Melanie Chou

Theses and Dissertations

Aim: The aim of this study is to determine the frequency of single nucleotide polymorphisms (SNPs) in various pattern recognition receptor (PRR) genes, including Toll like receptors (TLR) -2, -4, -9, and CD14 in chronic (CP), localized (LAP) and generalized aggressive (GAP) periodontitis and periodontally healthy (NP) patients in an African American population. Methods: A total of 205 subjects were involved in the study. The LAP group consists of 25 subjects, the GAP group 50 subjects, the CP group 73 subjects and the NP group 57subjects. Genotyping was performed in TLR2 (G2408A), TLR4 (A896G),TLR9 (T1486C) and CD14 (C260T) genes by …

Influence Of A Serotonin Transporter Promoter Polymorphism (5-Httlpr) On Corticolimbic Abnormalities In Bipolar Disorder An Integrated Genetics And Functional Mri Study, Maulik Shah

Yale Medicine Thesis Digital Library

Bipolar disorder (BD) is associated with abnormalities of the subgenual anterior cingulate cortex (sgACC) and the amygdala, components of a corticolimbic neural system that subserves emotional regulation. The short s allele - as opposed to the long l allele - of a serotonin transporter promoter (5-HTTLPR) polymorphism is associated with more severe course features of BD and impaired functional connectivity between the sgACC and amygdala in healthy control (HC) individuals. This study tests the hypothesis that the s allele influences the dysfunction in the sgACC-amygdala neural system in BD. Twenty-six euthymic BD participants (17 s carriers, 9 ll) and 43 …

The Alestle - Vol. 61 No. 65 - 06/03/2009, Southern Illinois University Edwardsville

The Alestle

Vol. 61 No. 65

Flo Oy Wong Interview, Angelika Piwowarczyk

Asian American Art Oral History Project

2009 interview with Chinese American multimedia artist Flo Oy Wong by Angelika Piwowarczyk

http://www.flo-oy-wongartist.com/

An Irresistible Invitation: Enhancing Academic Publication In Rhetoric And Composition By Inviting Online Peer Commentary, Sarah L. Cutler

Theses and Dissertations

In many ways the current publishing system in rhetoric and composition, which centers on the peer-reviewed journal, undermines core values we hold for ideal scholarly communication. These values include collaboration, dialogue, participation, and public engagement. Though the current system's methods of preserving, distributing, and maintaining quality control of scholarly work contradict our values, technological developments have made possible alternative publishing models that could better uphold our values. Developing a preprint archive where scholars develop and share ideas before submitting them for publication in traditional peer-reviewed journals would bring our publishing process closer to our ideals.

Fy2009 Fiscal Close Report From Innovative Interfaces Acquisitions Module

Technical Services Reports and Statistics

Fiscal close report produced by the Acquisitions module of the University of Rhode Island's Innovative Interfaces Millennium integrated library system.

Indicates total spending on library materials from July 1, 2008 through June 30, 2009.

Specifically, provides appropriations, final expenditures, and encumbrances for monographs by fund code, including approval plan orders, firm orders, standing orders.

Also provides expenditures for serials and other subscriptions by fund code.

This year's data does not include expenditures from endowment funds.

Other years are found in Digital Commons@URI as supplementary files to the annual report of the library acquisitions department.

A Comparison Of Fluoroquinolones Versus Other Antibiotics For Treating Enteric Fever: Meta-Analysis, Durrane Thaver, Anita K. M. Zaidi, Julia Critchley, Asma Azmatullah, Syed Ali Madni, Zulfiqar Ahmed Bhutta

Department of Paediatrics and Child Health

Objectives: To review evidence supporting use of fluoroquinolones as first line agents over other antibiotics for treating typhoid and paratyphoid fever (enteric fever).
Design: Meta-analysis of randomised controlled trials. Data sources: Cochrane Infectious Diseases Group specialised register, CENTRAL (issue 4, 2007), Medline (1966-2007), Embase (1974-2007), LILACS (1982-2007), selected conferences, reference lists, and ongoing trial register (November 2007).
Review methods: Trials comparing fluoroquinolones with chloramphenicol, cephalosporins, or azithromycin in culture-proven enteric fever were included. Two reviewers extracted data and assessed methodological quality. Odds ratios with 95% confidence intervals were estimated. Trials recruiting over 60% children were analysed separately from trials on …

Transition State Structures And The Roles Of Catalytic Residues In Gap-Facilitated Gtpase Of Ras As Elucidated By (18)O Kinetic Isotope Effects, Xinlin Du, Stephen R. Sprang

Biological Sciences Faculty Publications

Ras-catalyzed guanosine 5' triphosphate (GTP) hydrolysis proceeds through a loose transition state as suggested in our previous study of (18)O kinetic isotope effects (KIE) [ Du , X. et al. ( 2004 ) Proc. Natl. Acad. Sci. U.S.A. 101 , 8858 - 8863 ]. To probe the mechanisms of GTPase activation protein (GAP)-facilitated GTP hydrolysis reactions, we measured the (18)O KIEs in GTP hydrolysis catalyzed by Ras in the presence of GAP(334) or NF1(333), the catalytic fragment of p120GAP or NF1. The KIEs in the leaving group oxygens (the beta nonbridge and the beta-gamma bridge oxygens) reveal that chemistry is …

Two-Dimensional Matter: Order, Curvature And Defects, Mark Bowick, Luca Giomi

Physics - All Scholarship

Many systems in nature and the synthetic world involve ordered arrangements of units on two-dimensional surfaces. We review here the fundamental role payed by both the topology of the underlying surface and its detailed curvature. Topology dictates certain broad features of the defect structure of the ground state but curvature-driven energetics controls the detailed structured of ordered phases. Among the surprises are the appearance in the ground state of structures that would normally be thermal excitations and thus prohibited at zero temperature. Examples include excess dislocations in the form of grain boundary scars for spherical crystals above a minimal system …

"Cloud Busters": Reflections On The Right To Water In Clouds And A Search For International Law Rules, Tarek Majzoub, Fabienne Quillere-Majzoub, Mohamed Abdel Raouf, Mira El-Majzoub

Colorado Environmental Law Journal

No abstract provided.

Mustang Daily, June 2, 2009

Cal Poly Student Newspaper

Student newspaper of California Polytechnic State University, San Luis Obispo, CA.

Concentrated, Non-Foaming Solution Of Quaternary Ammonium Compounds And Methods Of Use, Cesar M. Compadre, Philip J. Breen, Hamid Salari, E. Kim Fifer, Danny L. Lattin, Michael F. Slavik, Yanbin Li, Timothy O'Brien, Amy L. Waldroup, Thomas F. Berg

Patents Granted

A concentrated quaternary ammonium compound (QAC) solution with a concentration from greater than about 10% by weight and at least one solubility enhancing agent, such as an alcohol, is disclosed. A diluted QAC solution is used to contact food products to prevent microbial growth on the food products from a broad spectrum of foodborne microbial contamination. A method of contacting the food products with the dilute QAC for an application time of at least 0.1 second is disclosed. The foods that can be treated by this method are meat and meat products, seafood, vegetables, fruit, dairy products, pet foods and …

Letting The Genes Out Of The Bottle: Making The Most Of Free Bioinformatics Information, Don Macmillan

Proceedings of the IATUL Conferences

No abstract provided.

The Pulling Power Of Marquee Courses: The Changing Curriculum And Quality Reference Services, Maureen Cech, Nevenka Zdravkovska, Robert Kackley

Proceedings of the IATUL Conferences

No abstract provided.

A New Brevicipitid Species (Brevicipitidae: Callulina) From The Fragmented Forests Of The Taita Hills, Kenya, Simon P. Loader, G. John Measey, Rafael O. De Sá, Patrick K. Malonza

Biology Faculty Publications

A new species Callulina dawida is described from the Taita Hills, Kenya. It is distinguished from other members of the genus on the basis of the degree of digital expansion. The species further differs from other members of the genus based on molecular sequence comparisons and on its call. The morphological variation in the new species is described, including a comparison of internal and external characters and sexual dimorphism with other species of Callulina. The conservation status of the species, on the basis of its restricted distribution and land use changes in the area, is considered to be of …

Failure To Replicate A Genetic Association May Provide Important Clues About Genetic Architecture, Casey S. Greene, Nadia M. Penrod, Scott M. Williams, Jason H. Moore

Dartmouth Scholarship

Replication has become the gold standard for assessing statistical results from genome-wide association studies. Unfortunately this replication requirement may cause real genetic effects to be missed. A real result can fail to replicate for numerous reasons including inadequate sample size or variability in phenotype definitions across independent samples. In genome-wide association studies the allele frequencies of polymorphisms may differ due to sampling error or population differences. We hypothesize that some statistically significant independent genetic effects may fail to replicate in an independent dataset when allele frequencies differ and the functional polymorphism interacts with one or more other functional polymorphisms. To …

Bub2 Regulation Of Cytokinesis And Septation In Budding Yeast, Su Young Park, Addie E. Cable, Jessica Blair, Katherine E. Stockstill, Katie Shannon

Biological Sciences Faculty Research & Creative Works

Background: The mitotic exit network (MEN) is required for events at the end of mitosis such as degradation of mitotic cyclins and cytokinesis. Bub2 and its binding partner Bfa1 act as a GTPase activating protein (GAP) to negatively regulate the MEN GTPase Tem1. The Bub2/Bfa1 checkpoint pathway is required to delay the cell cycle in response to mispositioned spindles. In addition to its role in mitotic exit, Tem1 is required for actomyosin ring contraction.

Results: To test the hypothesis that the Bub2 pathway prevents premature actin ring assembly, we compared the timing of actin ring formation in wild type, bub2Δ …

Identifying Sleep Regulatory Genes Using A Drosophila Model Of Insomnia, Laurent Seugnet, Yasuko Suzuki, Matthew S. Thimgan, Jeffrey Donlea, Sarah I. Gimbel, Laura Gottschalk, Stephen P. Duntley, Paul J. Shaw

Biological Sciences Faculty Research & Creative Works

Although it is widely accepted that sleep must serve an essential biological function, little is known about molecules that underlie sleep regulation. Given that insomnia is a common sleep disorder that disrupts the ability to initiate and maintain restorative sleep, a better understanding of its molecular underpinning may provide crucial insights into sleep regulatory processes. Thus, we created a line of flies using laboratory selection that share traits with human insomnia. After 60 generations, insomnia-like (ins-l) flies sleep 60 min a day, exhibit difficulty initiating sleep, difficulty maintaining sleep, and show evidence of daytime cognitive impairment. ins-l flies …

Occurrence Of Camponotus Pennsylvanicus (Hymenoptera: Formicidae) In Trees Previously Infested With Enaphalodes Rufulus (Coleoptera: Cerambycidae) In The Ozark Mountains Of Arkansas, Robin M. Verble, Fred M. Stephen

Biological Sciences Faculty Research & Creative Works

Black carpenter ants, Camponotus pennsylvanicus (DeGeer), are nearly ubiquitous in North American forests. These ants are documented as predators of red oak borer, Enaphalodes rufulus (Haldeman), a native longhorn beetle that experienced an unprecedented population increase synonymous with an oak decline event in the oak hickory forests of the Ozark Mountains of Arkansas from the late 1990s until 2005. We examined previous red oak borer emergence holes, tree crown conditions, and site aspects in 13 pre-established vegetation monitoring plots and correlated these forest and tree attributes with the presence or absence of black carpenter ants. At each site, all red …

Purple Martin, Progne Subis, In San Luis Obispo County Riparian Habitat: Presence, Persistence, Nesting, Brooding And Reproductive Success, Shannon Eileen Murphy

Biological Sciences

The State of California, as of 2002, identified the Purple Martin as a bird species of Special Concern (Airola et al., 2003). These migrants were historically found in a unique habitat in Central California; nesting in natural cavities of Western Sycamores within Riparian Habitats. I am proposing that Purple Martins still successfully nest and brood young in this unique habitat in San Luis Obispo County. The primary study site is in Atascadero where Highway 41 meets San Gabriel Road and San Gabriel Road crosses Atascadero creek. The secondary site is Highway 58 in Santa Margarita where the highway crosses the …

Diversity, Distribution And Utilization Pattern Of Economically Important Woody Plants Associated With Agro-Forestry In District Rajouri, J & K (Northwest Himalaya), Jawaid Sarver, Satish Kumar, Mahroof Khan, Mehjabeen Ara, V. K. Anand

Ethnobotanical Leaflets

The extensive explorations carried out in the study area enabled us to identify 60 woody plant species (47 trees and 13 shrubs) associated with the agroforstry system. These species belonged to 48 genera and were distributed among 30 families. Rosaceae (11 spp.), Rutaceae (5spp.), Euphorbiaceae, Fabaceae, Mimosaceae, Moraceae and Pinaceae (3spp. each) were the species rich. Maximum species were found between the altitudes 1000-1800m. Forty seven species were used as fuel, 30 as medicine, 22 as edibles, 13 as fodder, 7 as timber, where as 4 species were used for making agriculture implements. Only one species was identified as rare, …

Year 2 Report, Microbial Source Tracking

EPA Study

This report covers the project from the end of the preliminary year 1 report, May 31, 2008 through May 31, 2009.

Archaeal Diversity And The Prevalence Of Crenarchaeota In Salt Marsh Sediments, Katelyn A. Nelson, Nicole S. Moin, Anne E. Bernhard

Biology Faculty Publications

Crenarchaeal 16S rRNA sequences constituted over 70% of the archaeal clones recovered from three salt marsh sites dominated by different grasses. Group I.1a Crenarchaeota dominated at two sites, while group I.3b Crenarchaeota sequences were most abundant at a third site. Abundances of 16S rRNA genes related to “Candidatus Nitrosopumilus maritimus” differed by site and sampling date.

Biology Gone Barefoot: Professor Teaches From Creationist View, Liberty University

June/July 2009

No abstract provided.

The Effect Of Particle Surface Area To Volume Ratio On Ion Release From Cocr Spheres, Darin J. Grandfield

Master's Theses

In 2005, over 200,000 Americans underwent a hip arthroplasty, the replacement of a hip joint with an artificial prosthesis. Of these arthroplasties, metal-on-metal type implants represent an increasing usage percentage. Metal-on-metal implants are selected largely for their low volumetric wear rate, durability, and resistance to corrosion. In spite of these advantages, little is known concerning the long-term consequences of heavy metal alloy use in the body, although early research indicates potentially carcinogenic results. This thesis is a preliminary investigation into these long term effects and their root causes.

An improved comprehension of the corrosion kinetics and the rate of ion …

Evaluating The Electrical Response Of Polyaniline To Mechanical Strain, Matthew L. Goebel

Master's Theses

This thesis focuses on the electrical output of polyaniline films subjected to uniaxial strain in hydrochloric acid solutions. Polyaniline belongs to novel class of materials known as conducting polymers. Alternating single and double bonds in the backbone of conducting polymers allow them to transmit electric charge when they are doped with negatively charged ions. Modifying the degree of doping and other electrical/chemical treatments allow conducting polymers to exhibit conducting, semi-conducting, or insulating electrical properties. Resilient mechanical properties, good processability, and low cost make conducting polymers good candidates for applications traditionally held by metals and semi-conductors.

When tensile strain is applied …

Faculty Impact Statements, 2008, Arkansas Agricultural Experiment Station

Agricultural Experiment Station Records

Each issue [in the Research Series] has a distinctive title

Past Is Prologue: Recent Carbon Regulation Disputes In Europe Shape The U.S. Carbon Future , Cameron Ferrey, Steven Ferrey

Journal of Environmental and Sustainability Law

No abstract provided.

Plain Language Interpretation Gone Awry: The New Paradigm Of Pesticides, Water Pollution, And The Inefficient, Ineffective Overlap Of Statutory Schemes. National Cotton Council Of America V. Epa, Michael C. Risberg

Journal of Environmental and Sustainability Law

No abstract provided.

A Whale Of A Tale: The Supreme Court Sets A New Trend Favoring National Security Over Environmental Concerns. Winter V. Nrdc, Brian Schierding

Journal of Environmental and Sustainability Law

No abstract provided.