Digital Commons Network^™

Evaluation Of A Social Support Measure That May Indicate Risk Of Depression During Pregnancy, Lori Spoozak

Yale Medicine Thesis Digital Library

The objective of this study was to evaluate the psychometric properties of the Kendler Social Support Interview modified for administration to pregnant women and to assess the relationship between social support and depression in the first trimester of pregnancy. Subjects were administered the Modified Kendler Social Support Interview (MKSSI) and the Composite International Diagnostic Index to diagnose depression. Principal components analysis was employed to construct the MKSSI score. Cronbachs coefficient alpha and principal factor analysis were run for items included in the MKSSI score. The relationship between a depressive diagnosis and the MKSSI score and subscales was assessed by logistic …

07-09-2009 Swosu Faculty Receive Research And Equipment Grants, Southwestern Oklahoma State University

THE BARK ARCHIVE 2009

Southwestern Oklahoma State University and Dr. Andrea Holgado, assistant professor in the SWOSU Department of Biological Sciences, were recently awarded an Oklahoma State Regents of Higher Education (OSRHE) grant

Abn Summer Tour Business Meeting, John Owens

John Owens: Speeches and Appearances

Several things to update you on tonight, including the $1 million in proposed budget cuts for IANR, the life sciences report that followed the review team's visit to campus in March, and we have a commitment for a new animal science department head I'm delighted to tell you about. I'm going to talk a bit about what we see as some of the major issues on the horizon for IANR in FY 10, and I want to end with several of the many good news pieces we could share. Then we'll hope to have some time for questions and discussion.

Summer Mustang, July 9, 2009

Cal Poly Student Newspaper

Student newspaper of California Polytechnic State University, San Luis Obispo, CA.

Monitoring, Identification, And Intervention For Metabolic Disorders In Veterans With Psychotic Disorders, Michael Swtye

Yale Medicine Thesis Digital Library

In light of growing evidence that certain antipsychotics may cause potentially life-threatening metabolic side-effects, the purpose of this study was to determine how regularly mental health clinicians (MHCs) currently monitor and manage metabolic abnormalities in overweight and obese patients with psychotic disorders. We hypothesized that MHCs monitor, identify and intervene for metabolic abnormalities in their patients at significantly lower rates than primary care physicians (PCCs), and that such rates may jeopardize patient health. We performed a one-year cross-sectional medical record review of primary care and mental health routine outpatient visit notes from the West Haven Campus of the Veteran Affairs …

Role Of Biomarkers In Monitoring Gaucher Disease And Potential Of Biomarkers To Illuminate Pathophysiologic Pathways, Hanna Yu

Yale Medicine Thesis Digital Library

Objectives: 1.) Assess utility of biomarkers as a surrogate endpoint and a reflection of total body burden of Gaucher cells by examining correlations between biomarkers and liver volume and characterizing biomarker response to enzyme replacement therapy (ERT), and 2.) to gain insight into pathophysiologic pathways of GD. Study Design: This is an observational study Subjects and Methods: 114 patients with both pretreatment and post-treatment data were identified. These patients were further subdivided into intact spleen and asplenic patients. Differences in means among the subgroups of patients were determined, then regression analyses were run to investigate correlations between biomarkers and liver …

2009-07-09 Unm News Minute, University Of New Mexico Communication And Marketing Department

UNM News Minute 2009

No abstract provided.

The Wrong Wright Stuff : Mapping Human Error In Aviation, Stacey Hendrickson

Psychology ETDs

The Aviation Safety Reporting System (ASRS) was instituted to aid the Federal Aviation Administration in tracking trends in aviation incidents so that, ultimately, safety measures and training could be implemented to decrease the occurrence of accidents and incidents within the industry. The current system relies on hand coding of reports to recognize current trends and alert the proper parties. Although the filing party may enter some codified data describing the surrounding scenario (e.g., time of day, weather), there is no opportunity to specify a category if the problem is human error. Considering the prevalence of human error within these incidents …

Chimeras And Jagunços: Positivist Discourse In Euclides Da Cunha's Os Sertões, Justin Barber

History ETDs

The present study elucidates the discursive practice of positivism, as particularly manifested in late nineteenth-century Brazil. Founded in 1889, the Republic of the United States of Brazil was constructed as a positivist state by republican idealists and pragmatic oligarchs; the political embodiment of ordem e progresso (order and progress). It was a form of government meant to overcome Brazils imagined and concrete backwardness by strictly adhering to the Natural Laws identified by Auguste Comte, Charles Darwin, and, in particular, Herbert Spencer. Positivist progress was, however, contingent upon the elimination of the pathological, amorphous 'savage lower races. Non-white degeneration in Brazil, …

Creating An Expected Profile For Affinity 2.5 From A Sample Of Non-Pedophilic, Exclusively Heterosexual, College Age Males, R. D. C. Boardman

Theses and Dissertations

The Affinity 2.0 has been recently upgraded to the Affinity 2.5. Both instruments purport to measure sexual interest using viewing time as a form of measurement using non-pornographic images of people of varying ages and genders. The Affinity 2.5 increased the number of slides by 42.9%. This increase may have impacted the expected Chi square weights established for the Affinity 2.0 for non-pedophilic, exclusively heterosexual males. The purpose of this study was to create new expected Chi square weights for the Affinity 2.5 for non-pedophilic, exclusively heterosexual males. Additionally, this study re-examined the temporal stability of the Affinity 2.0 using …

Daily Eastern News: July 09, 2009, Eastern Illinois University

July

No abstract provided.

Ccm2 Molecular Signaling Pathway, Arianne J. Boylan

Yale Medicine Thesis Digital Library

Cerebral cavernous malformations (CCM) are a central nervous system vascular malformation often responsible for hemorrhagic strokes. Molecular genetic studies have identified three genes (CCMl KRITI, CCM2 Malcavernin, and CCM3 PDCDIO) and four possible loci responsible for the pathogenesis of these lesions. CCMl functions through integrin signaling and regulation of RACl activity and may be involved in the MAPK and JNK signaling cascades. We hypothesized that CCM2 likely functioned through the same pathways and that CCM3 expression is regulated by these stress-induced signaling cascades. We showed that CCM2 likely functions through the MAPK pathway as the mouse homolog, osmosensing scaffold protein …

Intussusception Of The Appendix: New Trends And Comprehensive Analysis Of 140 Case Reports, Barbara Wexelman

Yale Medicine Thesis Digital Library

INTUSSUSCEPTION OF THE APPENDIX: NEW TRENDS AND COMPREHENSIVE ANALYSIS OF 140 PUBLISHED CASE REPORTS. Barbara A. Wexelman, Cassius Ochoa Chaar, and Walter Longo. Section of Colorectal Surgery, Department of Surgery, Yale University, School of Medicine, New Haven, CT. Statement of Purpose: This paper uses 139 published case reports to understand the demographic, diagnostic, and treatment trends of intussusception of the appendix. Methods: Using the PubMed literature search engine to find all English references of intussusception and appendix, and reviewing those that contained actual case reports of intussusception of the appendix, we analyzed the demographics, presentation, diagnostic methods, surgical treatment, and …

Palmitic Acid Increases Enac Expression And Contributes To Insulin Resistance In Renal Distal Tubule, Timmy Sullivan

Yale Medicine Thesis Digital Library

Insulin resistance and obesity are two conditions associated with hypertension. Although the causes of hypertension are likely to be multifactorial, dysregulation of renal distal tubule sodium reabsorption may play a role. It has been shown that insulin increases sodium reabsorption in the distal tubule through the increased expression of epithelial sodium channels (ENaC); and obesity has been shown to cause insulin resistance in various tissues. Thiazolidinediones (TZDs) are insulin-sensitizing drugs whose use can be limited by a side effect of fluid-retention leading to edema and congestive heart failure. We set out to determine if the expression of ENaC in distal …

"Sparks From Law's Anvil": The Evolution Controversies In New Mexico, 1925-2008, Peter Incaudo

History ETDs

After attaining statehood in 1912, New Mexico witnessed an influx of American people, culture and controversies. This thesis tracks the development of controversies over the theory of evolution in the public schools of the state of New Mexico during the twentieth century and into the twenty-first century. Beginning with the states reaction to the 1925 Scopes trial, I discuss the reasons that the evolution controversy remained largely muted in 1920s New Mexico. Next, I examine the brief, but unique, 1927 evolution controversy sparked by a rumor of legislation to mandate the teaching of evolution. From there, I describe New Mexico's …

The Alestle - Vol. 60 No. 70 - 07/09/2008, Southern Illinois University Edwardsville

The Alestle

Vol. 60 No. 70

The 'Uncanny' And The Android, Noah Cooperstein

Foreign Languages & Literatures ETDs

The character of the android is found widely in film and literature. While she appears across the entire spectrum of genres, she most often makes her appearance in the uncanny text. This appearance is nearly always accompanied by some variation of the vision motif. Despite wide spread interest in both the Uncanny' and the android, to date, there is not a theory which accounts for the uncanny nature of the android and the prevalence of the vision motif in the android text. This paper will attempt to develop just such a theory. Any paper that addresses the 'Uncanny' must begin …

Negotiating Power, Identity And Mutuality: Graduate Students In Relation With Faculty, Administrators And Each Other, Donald Halquist

Language, Literacy, and Sociocultural Studies ETDs

While the collaborative practices of classroom teachers, teacher educators and preservice teachers have been well documented, less is known about the collaborative experiences of graduate students. The purpose of this qualitative study was to (a) describe and systematically analyze the collaborative and shared experiences of four graduate students who worked together for two and one-half years as part of a technology professional development project, (b) describe, through the voice of the graduate students, learning experiences that ran parallel to their formal doctoral education, and (c) demonstrate ways to link practitioner research and critical incidents. Through the study, I explored aspects …

Synthesis And Coordination Chemistry Of New Oxazoline And Benzoxazole Based Ligands With Lanthanides, Edicome Cornel Shirima

Chemistry and Chemical Biology ETDs

In Chapter 1, a brief literature review on the chemistry of lanthanides (Ln) and actinides (An) is described. In addition, the coordination chemistry of lanthanides/actinides with various ligands comprised of organic backbones has also been described. In Chapters 2 and 3 the syntheses of oxazoline and benzoxazole ligands is described. Both ligands contain a hard donor group (P=O) and the nitrogen (N) atom from the heterocycle as a relatively softer donor atom. In Chapter 2 the oxazoline ligand was synthesized in two steps reaction that involves substitution with Ph₂P group and oxidation of the phosphine into P=O by …

Salmonella Enterica Serovar Typhimurium Adhesion And Cytotoxicity During Epithelial Cell Stress Is Reduced By Lactobacillus Rhamnosus Gg, Kristen Burkholder, Arun K. Bhunia

Department of Food Science Faculty Publications

Background

Physiological stressors may alter susceptibility of the host intestinal epithelium to infection by enteric pathogens. In the current study, cytotoxic effect, adhesion and invasion of Salmonella enterica serovar Typhimurium (S. Typhimurium) to Caco-2 cells exposed to thermal stress (41°C, 1 h) was investigated. Probiotic bacteria have been shown to reduce interaction of pathogens with the epithelium under non-stress conditions and may have a significant effect on epithelial viability during infection; however, probiotic effect on pathogen interaction with epithelial cells under physiological stress is not known. Therefore, we investigated the influence of Lactobacillus rhamnosus GG and Lactobacillus gasseri …

The Effect Of Aging On The Innate Immune Response Of Vascular Smooth Muscle, Christopher Winterbottom

Yale Medicine Thesis Digital Library

As our understanding of atherosclerosis has become more sophisticated, a picture of the disease has emerged which emphasizes the role of inflammation in the pathogenesis of the disease, including signaling cascades mediated by toll-like receptors (TLRs). Data has also emerged suggesting that the process of aging plays an important role in atherogenesis, through pathways at least partially mediated by changes in the function of vascular smooth muscle cells. The purpose of this study was to elucidate the role that aging might play in the TLR-dependent innate immune response of vascular smooth muscle. Ex vivo cell and tissue culture models were …

Central Florida Future, Vol. 41 No. 59, July 9, 2009

Central Florida Future

Confirmed cases of H1N1 at UCF surging; Uncover Thursdays; Superman complex; Plus: Alligators and mini-golfing; Braving the heat for a Fourth party; UCF predicts recession's end; Conservationists looking out for Playboy bunnies; Machen: UCF 'adequate'.

Ion Transport Behaviors Upstream And Downstream From The Sampling Cone Of An Inductively Coupled Plasma Mass Spectrometer, Haibin Ma

Theses and Dissertations

Inductively coupled plasma - mass spectrometry (ICP-MS) is the technique of choice worldwide for trace elemental determinations because of its excellent ionization ability, low detection limits and fast analysis speeds. However, the ICP-MS still suffers from some disadvantages, such as spectral overlap and severe matrix effects. Matrix effects or interferences, partly arise from changes in the analyte transmission through the interfacial region between the ICP and mass spectrometer with changes in sample matrix. Better understanding of the transmission behaviors of analyte through the sampling and skimmer cones will provide the insights needed to alleviate matrix interferences and to improve the …

Relaxation Of Vibrationally Excited Trifluorobenzene And Tetrafluorobenzene By Collisions With Carbon Dioxide, Alan M. Johnson

Theses and Dissertations

An investigation into the relaxation of highly vibrationally excited trifluorobenzene and tetrafluorobenzene following collisions with carbon dioxide was performed using diode laser transient absorption spectroscopy. A 248 nm excimer laser prepared the vibrationally hot (E'~41,000 cm-1) fluorobenzene molecules. Large amounts of translational and rotational energy are transferred through collisions between the hot donor molecule and CO2. Rate constants and collisional probabilities were calculated by probing the high J states (J=58~80) of CO2 in the vibrational ground state, 0000, with measurements taken 1 µsec, ¼ the mean gas collision time, following each excimer laser pulse. The energy transfer probability distribution function, …

The Human Side Of Change: Towards A Pragmatic, Evolutionary Conception Of Cognition And Emotion In Organizational Change, Jason Smith

Theses and Dissertations

This dissertation synthesizes and analyzes an emblematic sample of three prevalent psychological approaches to organizational change and learning, giving particular attention to the conception of cognition and emotion. It also explores some of the philosophical and psychological assumptions undergirding these approaches. A web model depicting various epistemological influences is offered as a tool for exploring influences on the psychological research within and beyond this study. A second conceptual model is also offered as a tool for considering the hierarchical treatment and preferential placement of cognition over emotion theory and practice. The project draws on general philosophy, psychology, evolutionary theory, and …

Sphingosine Kinase 1 Inhibitor, A Novel Inducer Of Autophagy, Daniel Meza

Theses and Dissertations

Autophagy is the process of “cell self-eating” which has been implicated both in cell survival and cell death. Sphingosine kinase 1 (SphK1) regulates the intracellular balance between ceramide and sphingosine, bioactive lipids associated with cell death, and sphingosine-1-phosphate (S1P), whose actions are associated with survival and proliferation. Previous studies have implicated upregulation of SphK1 in the induction of autophagy. In this study, SK1-I, a SphK1 specific competitive inhibitor, induced autophagy in a concentration and time dependent manner in HCT116 colorectal carcinoma cells. This autophagic response was observed to be more intense in wild type p53 expressing HCT116 cells than in …

Contemporary Daughter/Son Adult Social Role Performance Rating Scale And Interview Protocol: Development, Content Validation, And Exploratory Investigation, Dana Everett Cozad

USF Tampa Graduate Theses and Dissertations

The purpose of this study was to develop and content validate a Performance Rating Scale and Interview Protocol, enabling study of the social role performance of adult daughters and sons as they fulfill the societal norms and expectations of adult children. This exploratory investigation was one of 13 contemporary adult social roles completed by the University of South Florida Social Roles Research Group to update research of Havighurst in the 1950s.

The Daughter/Son Performance Rating Scale and Interview Protocol were created through a series of panel reviews and suggestions by experts drawn from adult education, human development, gerontology, and educational …

Everymans Argot, Kamarie Chapman

Theatre & Dance ETDs

This paper discusses different methods and theories in playwriting, specifically the importance of dramatic structure and the value of cultural awareness as a playwright. Many of the theories discussed range from Aristotle to more contemporary feminist theorist such as Marie Irene Fornes. It is followed by the play Deception Pass: An American Story, one of the plays discussed within the essay.

Nanofiber Scaffolds With Gradations In Mineral Content For Mimicking The Tendon-To-Bone Insertion Site, Xiaoran Li, Jingwei Xie, Justin Lipner, Xiaoyan Yuan, Stavros Thomopoulos, Younan Xia

MIIR Faculty Research

We have demonstrated a simple and versatile method for generating a continuously graded, bonelike calcium phosphate coating on a nonwoven mat of electrospun nanofibers. A linear gradient in calcium phosphate content could be achieved across the surface of the nanofiber mat. The gradient had functional consequences with regard to stiffness and biological activity. Specifically, the gradient in mineral content resulted in a gradient in the stiffness of the scaffold and further influenced the activity of mouse preosteoblast MC3T3 cells. This new class of nanofiberbased scaffolds can potentially be employed for repairing the tendon-to-bone insertion site via a tissue engineering approach.

Single-Molecule Protein Unfolding In Solid State Nanopores, David Talaga, Jiali Li

Department of Chemistry and Biochemistry Faculty Scholarship and Creative Works

We use single silicon nitride nanopores to study folded, partially folded, and unfolded single proteins by measuring their excluded volumes. The DNA-calibrated translocation signals of β-lactoglobulin and histidine-containing phosphocarrier protein match quantitatively with that predicted by a simple sum of the partial volumes of the amino acids in the polypeptide segment inside the pore when translocation stalls due to the primary charge sequence. Our analysis suggests that the majority of the protein molecules were linear or looped during translocation and that the electrical forces present under physiologically relevant potentials can unfold proteins. Our results show that the nanopore translocation signals …