Digital Commons Network^™

Adrenergic Receptor Expression On Raw264.7 Macrophages, Lindsay Ward

Honors Theses

In this study, AR surface expression patterns and regulation via AR-catecholamine interactions were characterized. Macrophage function was shown to be regulated by catecholamines through both Alpha- and Beta-ARs, as evidenced by corresponding alterations in cytokine production. Treatment of activated macrophages with NE, a general catecholamine, or fomoterol, a P-AR agonist, produced significant decreases in TNF and IL-6 secretion. The effecis of clonidine, an Alpha-AR agonist, produced less consistent results, but clonidine-mediated enhancement of cytokine secretion appears to be mediated by Alpha-AR signaling. LPS was shown to noticeably change the surface expression ofboth types of ARs in RAW264.7 macrophages. However, NE …

Can She Ever Be "The Man"? : The Effect Of Gender On Implicit Perceptions Of Leadership Ability In An Applied Hiring Task, Rebecca S. Frazier

Honors Theses

Despite numerous advances in the eld of women's rights and a general decline in explicit discrimination, there still exists a dramatic lack of women in leadership positions across America. This research seeks to expand upon past studies suggesting that there is a basic cognitive incongruency between traditional male and leadership roles which leads ordinarily "unbiased" individuals to perceive women as less suited r leadership positions than men. Thus, this experiment investigates the implicit biases against women leaders by asking if the subtle addition of gender information alters individuals' initial impressions of leadership capability in an applied hiring task involving resumes, …

An Ounce Of Prevention: Why The Innocence Movement Should Focus On Proscriptive Pre-Conviction Measures Instead Of Abolition Of The Death Penalty, Rhiannon M. Hartman

Richmond Journal of Law and the Public Interest

When eyewitnesses identify defendants as perpetrators during criminal trials, juries almost always return a guilty verdict. Unfortunately, researchers consistently find that eyewitness identification is inherently inaccurate and unreliable. The Supreme Court of the United States acknowledged the broad scope of the problem as early as 1967, when it referenced Edwin M. Borchard's famous study of wrongful convictions, stating, "the vagaries of eyewitness identification are well-known; the annals of criminal law are rife with instances of mistaken identification."' Since Borchard's 1932 study, there has been no remedy for the problem of wrongful conviction based on mistaken identification. In Samuel Gross's study …

Adopting A New Approach To Medical Information For Adoptees, Jessica Marie Yoke

Richmond Journal of Law and the Public Interest

Some estimates indicate that at least six million adoptees lived in the United States in 1997. "After factoring in birth parents and adoptive parents for each adoptee, the number of persons directly affected by the adoption process grows to over [twenty-four million] persons." States conducted many of these adoptions privately, particularly those that did not occur recently, so the parties remain anonymous to one another. Thus, an enormous number of Americans are now struggling in a system built on antiquated law that is not very useful, and in fact might be harmful. This Comment proposes a solution to this overlooked …

Schools, Mandates, And Money: Education In The 2009 Session Of The Virginia General Assembly, Angela A. Ciolf, Sarah A. Geddes

Richmond Journal of Law and the Public Interest

This article will recount the development of this year's revisions to the 2008-2010 budget, examine the long-term implications of budgetary decisions affecting public education, and review notable pieces of substantive education legislation. It will also highlight the major features of the new Standards of Accreditation-implementing graduation rate accountability-and special education regulations. Finally, this article will offer a framework for analyzing the critical education-funding decisions likely to come before the 2010 General Assembly as Virginia continues to feel the effects of a global economic crisis.

Hydroxyl Radical Is Produced Via The Fenton Reaction In Submitochondrial Particles Under Oxidative Stress: Implications For Diseases Associated With Iron Accumulation, Carin Thomas, Melissa M. Mackey, Amy A. Diaz, David P. Cox

All Faculty Scholarship for the College of the Sciences

Mitochondrial dysfunction and reactive oxygen species (ROS) are often implicated in diseases involving oxidative stress and elevated iron. As mitochondria produce ATP by oxidative phosphorylation, ROS by-products are generated from the electron transport chain. Although superoxide and hydrogen peroxide have been thoroughly investigated, little evidence documents hydroxyl radical (HO•) production in mitochondria. In order to determine whether HO• is generated under oxidative stress conditions by a Fenton-type mechanism, bovine heart submitochondrial particles were examined for HO• in the presence and absence of iron ligands, antioxidant enzymes and HO• scavengers. HO• was measured as 2,3- and 2,5-dihydroxybenzoic acid (DHBA), using HPLC …

Sequences Of Tibetan Macaque (Macaca Thibetana) And Tourist Behaviors At Mt. Huangshan, China, Maureen S. Mccarthy, Megan D. Matheson, Jack D. Lester, Lori K. Sheeran, Jin-Hua Li

Biology Faculty Scholarship

Previous research on Tibetan macaques (Macaca thibetana) at Mt. Huangshan, China, suggested that ecotourism can have detrimental consequences. This study identified sequences of behaviors that typically occur in macaque-tourist interactions to examine whether particular tourist behaviors precipitate monkey responses. Focal sampling was used to record relevant behaviors from tourists and 10 macaques over 28 data collection sessions in August 2006. Data collectors recorded whether each behavior occurred as part of a sequence. Sequences were defined as two or more behaviors in which each behavior occurred within five seconds of the previous behavior. Of 3,129 total behaviors, 2,539 (81.1%) …

Biofuels: Potentials, Problems & Solutions, Richard L. Ottinger

Elisabeth Haub School of Law Faculty Publications

Biofuels have the exciting potential of mitigating the grave threats of global warming, reducing the world's dependence on imported oil from insecure sources and of reducing the skyrocketing costs of oil that are threatening to undermine the world's economies and devastating the people in non-oil producing, developing countries. For the people in these countries, biofuel offer a promising road to enhance development since they use local materials, can provide local jobs, and do not require the import of expensive equipment and expertise. Brazil has been the pioneer in the use of biofuel, allowing it to eliminate its oil imports, becoming …

Sfa Gardens Scrapbook 2005-2009, Sfa Gardens, Stephen F. Austin State University

SFA Gardens Scrapbooks

No abstract provided.

Gordie News, January 2009, West Chester University Of Pennsylvania

Gordon Natural Area History & Strategic Plan Documents

No abstract provided.

Gordon Natural Area (Gna) - (2009) - An Ecological Treasure Island In A Sea Of Development, Gerard Hertel

Gordon Natural Area History & Strategic Plan Documents

No abstract provided.

Analysis Of Lesion Border Segmentation Using Watershed Algorithm, Hanzheng Wang

Masters Theses

"Automatic lesion segmentation is an important part of computer-based skin cancer detection. A watershed algorithm was introduced and tested on benign and melanoma images. The average of three dermatologists' manually drawn borders was compared as the benchmark. Hair removing, black border removing and vignette removing methods were introduced in preprocessing steps. A new lesion ratio estimate was added to the merging method, which was determined by the outer bounding box ratio. In postprocessing, small blob removing and border smoothing using a peninsula removing method as well as a second order B-Spline smoothing method were included. A novel threshold was developed …

Automated Offspring Sizing In Evolutionary Algorithms, André Chidi Nwamba

Masters Theses

"Evolutionary Algorithms (EAs) are a class of algorithms inspired by biological evolution. EAs are applicable to a wide range of problems; however, there are a number of parameters to set in order to use an EA. The performance of an EA is extremely sensitive to these parameter values; setting these parameters often requires expert knowledge of EAs. This prevents EAs from being more widely adopted by nonexperts. Parameter control, the automation of dynamic parameter value selection, has the potential to not only alleviate the burden of parameter tuning, but also to improve performance of EAs on a variety of problem …

Time-Weighted Average Solid-Phase Microextraction (Twa-Spme) For In-Planta Detection Of Chlorinated Solvents, Emily Moore Sheehan

Masters Theses

"Recent interest in the use of phyto-mapping for plume delineation at contaminated sites has promoted a need for new and innovative sampling techniques. Solid-phase micro-extraction (SPME) methods have been developed as a chemical analysis tool offering fast, simple, non-invasive sampling without the use of solvents. In this study SPME devices were tested for applicability for in-planta detection of chlorinated solvents. To evaluate the use of SPME for VOCs in-planta a number of integrated studies were undertaken. Uptake profiles were developed for nine chlorinated solvents in a liquid polydimethylsiloxane (PDMS) matrix with 100 µm Carboxene SPME fibers. Timeweighted average (TWA) sampling …

Electricity Generation And Ethanol Production Using Iron-Reducing, Haloalkaliphilic Bacteria, Varun Paul

Masters Theses

"Microbial life in extreme environments has been studied primarily for their metabolic activities. Very few commercial or industrial applications have been known from these systems. In this study, the metabolic pathways and properties of bacteria from a haloalkaliphilic environment of Soap Lake, Washington were employed in two research applications related to energy production. In the first study, the bacterial cultures that were known to reduce iron (III) were used in a Microbial Fuel Cell (MFC) reactor. Iron reducing bacteria have shown to shunt their electrons on to the surface of a carbon electrode of an MFC, and the electrons can …

Exploring The Use Of A Commercial Game Engine For The Development Of Educational Software, Hussain Alafaireet

Masters Theses

"Three-dimensional visualization and simulation environments are becoming increasingly important in both industrial and educational environments. However, developing these simulations can be a difficult and expensive task. Herein we explore the use of a commercial game engine to develop a 3-D, interactive computer game designed to teach players about the anatomy of a frog. The goal of this project is threefold: 1) to develop high-fidelity virtual reality educational software with a limited budget and limited personnel, 2) to define a software development process by which similar simulations can be developed, and 3) to explore the benefits that these simulations provide to …

Development And Evaluation Of An Effective Process For The Recovery Of Oil And Detoxification Of Meal From Jatropha Curcas, Sarthak Gaur

Masters Theses

"There has been significant research on biofuels to ensure national security and economic stability of the US. Jatropha curcas, a hardy plant, holds tremendous potential as a biodiesel source and cattle feed-stock largely due to its high triglyceride and crude protein content. However, its viable economic utilization is limited due to the presence of important toxic compounds, phorbol esters. A novel and efficient process has been developed that obtains high yields of jatropha oil and detoxifies the defatted (oil free) jatropha meal. Principles of solid-liquid extraction were utilized to detoxify the meal and then liquid chromatography was employed to analyze …

Fault Detection And Prediction With Application To Rotating Machinery, Gary R. Halligan

Masters Theses

"In this thesis, the detection and prediction of faults in rotating machinery is undertaken and presented in two papers. In the first paper, Principal Component Analysis (PCA), a well known data-driven dimension reduction technique, is applied to data for normal operation and four fault conditions from a one-half horsepower centrifugal water pump. Fault isolation in this scheme is done by observing the location of the data points in the Principal Component domain, and the time to failure (TTF) is calculated by applying statistical regression on the resulting PC scores. The application of the proposed scheme demonstrated that PCA was able …

Nona-Arginine Peptides Facilitate Cellular Entry Of Semiconductor Nanocrystals: Mechanisms Of Uptake, Yi Xu

Masters Theses

"Luminescent semiconductor quantum dots (QDs) have recently been used for delivering and monitoring biomolecules, such as drugs and proteins. However, QDs alone have a very low efficiency of transport across the plasma membrane. In order to increase the efficiency of QD delivery, synthetic nona-arginine (sR9) was used, a cell penetrating peptide, to facilitate uptake. Data demonstrated that sR9 could significantly increase the cellular uptake of QDs by noncovalent binding between QDs and sR9. Furthermore, the mechanisms of QD/sR9 cellular internalization were investigated. Low temperature and metabolic inhibitors markedly inhibited the uptake of QD/sR9, indicating that internalization is an energy-dependent process. …

Misunderstood Symbolism: Rereading The Subjective Objects Of Robert De Montesquiou’S First Maison D’Un Artiste, Elizabeth Emery

Department of World Languages and Cultures Faculty Scholarship and Creative Works

This essay seeks to return Robert de Montesquiou-Fezensac to his rightful place as an important but misunderstood innovator whose aesthetic experimentation of the 1880s exerted a profound influence on those who would come to be known as ‘Symbolists’. I juxtapose Montesquiou's written descriptions of his interior decorations at an apartment at 41, Quai d’Orsay in Paris with the little-discussed photographs he had taken of this residence, probably in 1887 or 1888, in order to illuminate the originality of his vision.

Oxidative Stress, Calcium Homeostasis, And Altered Gene Expression In Human Lung Epithelial Cells Exposed To Zno Nanoparticles, Chuan-Chin Huang

Masters Theses

"The influence of 20 nm ZnO nanoparticles on oxidative stress, intracellular calcium homeostasis, and gene expression was studied in human bronchial epithelial cells (BEAS-2B). ZnO caused a concentration- and time-dependent cytotoxicity while elevating oxidative stress and causing membrane damage (cellular LDH release). There was a remarkably steep relationship between concentration and toxicity at concentrations from 5 to 10 μg/ml. Exposure to ZnO increased intracellular calcium levels in a concentration- and time-dependent manner. Treatment with the antioxidant N-acetylcysteine prevented cell loss and diminished the increase in intracellular calcium concentration, suggesting oxidative stress mediated cytotoxicity. Exposure to a sublethal concentration of ZnO …

Environmental Geochemistry Of Metal Contaminated Sediments From The Big River System Of Southeastern Missouri, Helen Carrie Bender

Masters Theses

"Geochemical analysis of stream sediments from the Big River Watershed of southeastern Missouri indicates that they contain elevated concentrations of contaminant metals such as Pb. Zn, Cu. Co, Ni and Cd. The elevated concentrations are derived from natural exposures of metal enriched strata and the numerous mine tailings piles and water seeps created as a result of about 300 years of lead-zinc mining in the “Old Lead Belt”. Galena (PbS), sphalerite (ZnS), and pyrite (FeS₂) are the primary sulfides found in the tailings piles and Scanning Electron Microscopy analysis of individual metallic sediment particles collected at intervals downstream …

In Vitro Evaluation Of Bioactive Glass Scaffolds And Modified Bioactive Glasses With An Osteogenic Cell Line, Vernon C. Modglin

Masters Theses

"This investigation consisted of two parts focused on bioactive glasses and scaffolds for in vitro growth of bone cells for tissue engineering and bone repair. The first part involved evaluation of the ability of two new types of porous 13-93 bioactive glass scaffolds to support the growth and differentiation of mouse MLO-AS cells, an established osteogenic cell line used as a model of developing bone tissue. The two scaffold types tested included 13-93 glass fiber and trabecular-like scaffolds seeded with MLO-AS cells and cultured for intervals of 2 to 12 days. Collectively, in vitro results indicate that the 13-93 glass …

An Evolutionary Algorithm Approach To Actuated Signal Timing Optimization Under Lane-By-Lane Detection Condition, Eric G. Strack

Masters Theses

"Motivated by the need to reduce congestion on the nation's roadway network, this research seeks to determine when a new detection scheme at actuated signalized intersections may help. This new detection scheme is called lane-by-lane detection. It "looks" at traffic in all lanes individually to determine the traffic volume on the roadway. Specifically, the problems addressed are investigating alternate signal timings and investigating the traffic volume's effect on performance of the detection scheme. For the alternate signal timings, an Evolutionary Algorithm (EA) was employed to identify the optimal signal timing. This algorithm creates signal timings and tests them in the …

Goodbye Homo Economicus: Cognitive Dissonance, Brain Science, And Highly Effective Collaborative Practice, Pauline H. Tesler

Hofstra Law Review

No abstract provided.

Holladay Towne Center, L.L.C., A Utah Limited Liability Company V. Brown Family Holdings, L.C., A Utah Limited Company : Reply Brief, Utah Court Of Appeals

Utah Court of Appeals Briefs (2007– 2019)

No abstract provided.

Ricky Angilau V. State Of Utah : Appellant's Reply Brief, Utah Court Of Appeals

Utah Court of Appeals Briefs (2007– 2019)

This is the reply brief of Ricky Angilau, who appeals from the denial of his petition for extraordinary relief entered in the Third District Court of Salt Lake County, State of Utah, the Honorable Vernice Trease presiding. This brief replies to the Sheriffs brief.

Coping Styles And Sex Differences In Depressive Symptoms And Delinquent Behavior, Lisa A. Kort-Butler

Department of Sociology: Faculty Publications

Building on research that links gender to differences in well-being and differences in stress exposure and vulnerability, the current study examines how coping styles are gendered in ways that may contribute to sex differences in depressive symptoms and delinquent behavior. The study disaggregates stress measures to reflect gender differences in the experience of stress, examining whether avoidant, approach, and action coping condition the relationship between stress and well-being. Regression analyses were conducted using data from the National Longitudinal Study of Adolescent Health. Results revealed sex differences and similarities. The interaction of avoidant coping and stress helped explain why girls had …

Dieting, Restraint, And Disinhibition Predict Women's Weight Change Over 6 Y, Jennifer S. Savage, Lesa R. Hoffman, Leann L. Birch

Department of Psychology: Faculty Publications

Background: Although disinhibited eating is positively associated with higher weight in women, it is not known whether restrained eating and dieting moderate the influence of disinhibited eating on weight change.

Objective: The objective was to investigate over 6 y the interactive effects of restrained and disinhibited eating and self-reported dieting to lose weight as predictors of weight gain in women.

Design: Data were collected from non-Hispanic white women (n = 163) every 2 y. Height and weight were measured in triplicate. Dietary restraint and disinhibition were assessed by using the Eating Inventory. Participants were also asked if they were …

Immune Responses To Methamphetamine By Active Immunization With Peptide-Based, Molecular Adjuvant-Containing Vaccines, Michael J. Duryee, Rick A. Bevins, Carmela M. Reichel, Jennifer E. Murray, Yuxiang Dong, Geoffrey M. Thiele, Sam D. Sanderson

Department of Psychology: Faculty Publications

Vaccines to methamphetamine (meth) were designed by covalently attaching a meth hapten (METH) to peptide constructs that contained a conformationally biased, response-selective molecular adjuvant, YSFKPMPLaR (EP54). Rats immunized with EP54-containing meth vaccines generated serum antibody titers to authentic meth, an immune outcome that altered meth self-administration. Immunization increased meth self-administration suggesting pharmacokinetic antagonism. The ability of immune sera to bind a METH-modified target protein dramatically decreased during and shortly after the meth self-administration assay, suggesting effective sequestration of free meth. However, the binding ability of immune sera to the METH-modified target protein was recovered 34 days after meth-free clearance time.