Digital Commons Network^™

Promoting Overall Health And Wellness Among Clients: The Relevance And Role Of Professional Counselors, Holly Fetter, Dennis W. Koch

Adultspan Journal

No abstract provided.

Impacts Of Climate Change On Indirect Human Exposure To Pathogens And Chemicals From Agriculture, Aba Boxall, A Hardy, S Beulke, T Boucard, L Burgin, Pd Falloon, Pm Haygarth, T Hutchinson, Rs Kovats, G Leonardi, Ls Levy, G Nichols, Sa Parsons, L Potts, D Stone, E Topp, Db Turley, K Walsh, Emh Wellington, Rj Williams

School of Geography, Earth and Environmental Sciences

Objective Climate change is likely to affect the nature of pathogens and chemicals in the environment and their fate and transport. Future risks of pathogens and chemicals could therefore be very different from those of today. In this review, we assess the implications of climate change for changes in human exposures to pathogens and chemicals in agricultural systems in the United Kingdom and discuss the subsequent effects on health impacts. Data sources In this review, we used expert input and considered literature on climate change; health effects resulting from exposure to pathogens and chemicals arising from agriculture; inputs of chemicals …

Seroprevalence Of Hepatitis B And C Viruses, Hiv, And Syphilis Infections Among Engaged Couples, Ahmet Alim, Muge O. Artan, Zeynep Baykan, Betul A. Alim

Saudi Medical Journal

OBJECTIVE: To evaluate seroprevalences of hepatitis B and C viruses, human immunodeficiency virus (HIV), and syphilis infections among engaged couples. METHODS: This is a cross-sectional study of all engaged couples enrolled at 20 Health Centers and one Maternity Center of Sivas Health Directorate between May and September 2005 in Sivas, a central Anatolian city, in Turkey. Seroprevalances of hepatitis B (HB) surface antigen (HBsAg), hepatitis B surface antibody (anti-HBs), anti-hepatitis C virus (HCV), anti-human immunodeficiency virus (anti-HIV), and syphilis was assessed. Serum samples of 1,332 participants of 666 couples were investigated. RESULTS: Age range of subjects was 15-74, and most …

Domestic Violence Rights Movement In Tanzania: An Exploration, Flora Peter Myamba

Dissertations

In Tanzania, the involvement of a social movement to addressing domestic violence is fairly recent (early 1990s) (Green, 1999; Hirsch, 2003; Michau, 2002; TAMWA, 1999). As has historically been the case in most African countries, domestic violence has remained largely invisible, being considered a normal custom, practice and tradition (Green, 1999; The New York Times, 2005; TAMWA, 1999). Efforts to address it have been regarded as shameful and pointless (TGNP, 1993). Indeed, cultural mores remain very contentious with regard to the activities of the Tanzanian domestic violence rights movement (DVRM). It is this conflict between the movement's efforts to educate …

The United States And The Asia-Pacific Region: National Interests And Strategic Imperatives, James J. Przystup

Strategic Forums

Notwithstanding the 2008–2009 financial crisis, East Asia today remains the home of the world’s most dynamic economies. In 1990, the region’s share of global gross domestic prod- uct (GDP) amounted to 26.5 percent; in 2006, that figure stood at 37.5 percent. In 2006, the GDP growth rate for Asia’s economies aver- aged 5.1 percent, compared to a world average of 3.9 percent.

A Global Architecture For Medical Counter-Measure Preparedness Against Bioviolence, Barry Kellman, Zachary D. Clopton

Cornell Law Faculty Publications

The obstacles to a functioning global infrastructure for bioviolence medical counter-measure (MCM) preparedness in the near future are legion. Naysayers could readily rattle off dozens of reasons why this or that initiative will not work, and they are right. The world is remarkably dysfunctional, and implementation of progressive reform in this context faces near infinite obstructions and frustrations. Moreover, there is scant evidence that global leaders consider such an infrastructure to be among their highest priorities.

The purpose of this article, however, is not to assess the political odds that such an infrastructure will be built soon; it is to …

Why Museums Matter: A Tale Of Pinworms (Oxyuroidea: Heteroxynematidae) Among Pikas (Ochotona Princeps And O. Collaris) In The American West [Critical Comment], Eric P. Hoberg, Patricia A. Pilitt, Kurt Galbreath

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Permanent and well-supported museum or natural history collections provide a solid foundation for the process of systematics research through creation of an empirical record which validates our understanding of the biosphere. We explore the role of museums in ongoing studies of the complex helminth fauna characteristic of pikas (Ochotona spp.) in the American west. These studies address the taxonomy for pinworms of the Labiostomatinae and the problems associated with the absence of adequate type series and vouchers and with misidentifications in original descriptions. We demonstrate that the types for Labiostomum (Labiostomum) coloradensis are identical to some specimens …

Associated Symptoms In The Ten Days Before Diagnosis Of Kawasaki Disease., Annette L. Baker, Minmin Lu, L Luann Minich, Andrew M. Atz, Gloria L. Klein, Rosalind Korsin, Linda Lambert, Jennifer S. Li, Wilbert Mason, Elizabeth Radojewski, Victoria L. Vetter, Jane W. Newburger, Pediatric Heart Network Investigators, Girish S. Shirali

Manuscripts, Articles, Book Chapters and Other Papers

OBJECTIVE: To describe common associated symptoms within the 10 days before diagnosis in subjects enrolled in the Pediatric Heart Network's trial of steroid therapy in Kawasaki disease (KD).

STUDY DESIGN: Patients with acute KD were enrolled between days 4 and 10 of illness at 8 centers between 2002 and 2004. We defined common associated symptoms as those occurring in >or=10% of patients. Principal clinical criteria for KD were not included in this analysis.

RESULTS: Among 198 patients, irritability was reported in 98 (50%), vomiting in 88 (44%), decreased food/fluid intake in 73 (37%), cough in 55 (28%), diarrhea in 52 …

Antiretroviral Therapy Dose Adjustments Based On Calculated Creatinine Clearance, J. Shavadia, G. Tesfaldet, Majid Twahir

Internal Medicine, East Africa

Background: Whereas therapy for HIV is dependent on level of creatinine clearance, most laboratories locally only report an absolute creatinine value. There is likelihood that the patients already on antiretroviral therapy (ART) may have required dosage adjustment at the time of initiation of therapy or sometime during ongoing therapy. This paper explores a group of patients who are already on ART to determine their creatinine clearance and assess the need for ART dose adjustment.

Objective: To determine the proportion of stable HIV outpatients who have a documented creatinine clearance (CrCI) and the proportion requiring antiretroviral drug dose adjustments depending on …

Identification Of An Rsh Gene From A Novosphingobium Sp. Necessary For Quorum-Sensing Signal Accumulation, Han Ming Gan, Larry Buckley, Ernő Szegedi, André O. Hudson, Michael A. Savka

Articles

The stringent response is a mechanism by which bacteria adapt to environmental stresses and nutritional deficiencies through the synthesis and hydrolysis of (p)ppGpp by RelA/SpoT enzymes. Alphaproteobacteria and plants contain a single Rsh enzyme (named for RelA/SpoT homolog) that is bifunctional. Here we report the identification of a new species of bacteria belonging to the genus Novosphingobium and characterization of an rsh mutation in this plant tumor-associated isolate. Isolate Rr 2-17, from a grapevine crown gall tumor, is a member of the Novosphingobium genus that produces the N-acyl-homoserine lactone (AHL) quorum-sensing (QS) signals. A Tn5 mutant, Hx 699, deficient in …

“The Womb People” : Detection, Treatment, And Prevention Of Cervical Cancer With The Khayelitsha Cervical Cancer Screening Project In Khayelitsha, South Africa, Kirsten Lynch

Independent Study Project (ISP) Collection

The current policy concerning cervical cancer screenings is not effectively addressing the specific needs of the female South African population. The program, as outlined by the South African Department of Health, is not sufficiently accessing women due to problems in availability, access, organization, and education. As women are living longer with HIV/AIDS, due to antiretroviral (ARV) treatment, they are becoming more susceptible to opportunistic infections that can lead to cervical cancer, such as Human strains of the virus can be prevented with administration of an HPV vaccination and advancement of precancerous lesions can be detected and treated with current technology. …

Bromeliads As A Breeding Site For The Dengue Vector Aedes Aegypti, Eva B. Shultis

Independent Study Project (ISP) Collection

Dengue Fever is a major public health concern in tropical and subtropical climates worldwide, including the city of Cairns, Australia, which is currently suffering a severe outbreak. The most important vector of the Dengue virus is the predominantly urban mosquito Aedes aegypti (L.), which lays its eggs in both artificial and natural containers, including the ornamental bromeliad plants found in many household gardens. The ability of larvae to develop to adulthood inside bromeliads has become controversial, however, and bromeliad enthusiasts frequently refuse to have their plants treated with insecticide. The aim of this study was to determine the conditions under …

Vih Y Alcohol En Arica, Chile: Percepciones De Portadores Y Profesionales, Lena Sessions

Independent Study Project (ISP) Collection

This paper investigated the relationship between alcohol consumption and HIV in Arica, Chile. The objectives of this investigation were to understand the demographics of HIV positive Ariqueños who consume alcohol, and understand their perceptions of alcohol consumption with respect to whether they believed they had a drinking problem, whether they believed that the consumption of alcohol facilitated their contracting HIV, and whether the consumption of alcohol affected their treatment. Although there is no literature that specifically addresses the topic of how HIV positive individuals who consume alcohol perceive their disease, former research suggests that a significant number (25-50%) of individuals …

Sustainable Commerce: Public Health Law And Environmental Law Provide Tools For Industry And Government To Construct Globally-Competitive Green Economies, T. Rick Irvin, Peter A. Appel

Scholarly Works

This Article examines the legal mechanics underlying the sustainable commerce private/public governance paradigm whereby industry and government create sustainable commerce initiatives which coordinately grow local/state economies and employment, enhance local/state competitiveness in the global marketplace, and at the same time substantially improve local/state public health and environmental infrastructure. This includes an examination of the legal foundation for state/local sustainable commerce initiatives drawn from existing public health and environmental law and a review of two specific local/state sustainable commerce initiatives which have followed this paradigm with impressive results over a two-to-four year timeframe. Part II of this Article examines how public …

Aku Newsletter : Spring 2009, Volume 10, Issue 1, Aga Khan University

The Aga Khan University Newsletters

No abstract provided.

The Trials And Tribulations Of Two Historians: Adjudicating Responsibility For Pollution And Personal Harm, David Rosner, Gerald Markowitz

Publications and Research

No abstract provided.

Comparison Of Immune Correlates, Age Related Changes And Proteomic Profiling Of Healthy Individuals Receiving Influenza Vaccines, Gaurav Basu

Theses and Dissertations in Biomedical Sciences

The burden of influenza related infections is substantial, both in terms of illness, lives lost and economic impact on society. The degree of impact of influenza related infections is much higher in the elderly population where it is a leading cause of catastrophic disability; greatly affecting the quality of life of elderly persons above 65 years of age. Vaccination is the mainstay for control and prevention of influenza infections. There are two vaccine formulations that are licensed for use at present. The inactivated influenza vaccines (TIIV) which have been used for 60 years in all age groups and the new …

Chironian Spring/Summer 2009, New York Medical College

The Chironian

No abstract provided.

Long-Distance Delivery Of Bacterial Virulence Factors By Pseudomonas Aeruginosa Outer Membrane Vesicles, Jennifer M. Bomberger, Daniel P. Maceachran, Bonita A. Coutermarsh, Siying Ye, George A. O'Toole, Bruce A. Stanton, Frederick M. Ausubel

Dartmouth Scholarship

Bacteria use a variety of secreted virulence factors to manipulate host cells, thereby causing significant morbidity and mortality. We report a mechanism for the long-distance delivery of multiple bacterial virulence factors, simultaneously and directly into the host cell cytoplasm, thus obviating the need for direct interaction of the pathogen with the host cell to cause cytotoxicity. We show that outer membrane–derived vesicles (OMV) secreted by the opportunistic human pathogen Pseudomonas aeruginosa deliver multiple virulence factors, including β-lactamase, alkaline phosphatase, hemolytic phospholipase C, and Cif, directly into the host cytoplasm via fusion of OMV with lipid rafts in the host plasma …

Utilizing Community Based Participatory Research To Address Health Literacy Issues: An Example In Southeastern Mn, Jennifer A. Weis

Theses and Graduate Projects

Low health literacy interferes with an individual's ability to reduce and treat preventable diseases. Given the spectrum of disease burden throughout the US, there are a number of important health topics deserving of our immediate attention in order to improve the public's health literacy. Overweight and obesity have surfaced as societal topics and any quest to improve health literacy must address these growing problems as they are likely to contribute to disease prevention and improved disease management. Unfortunately, the growing problem of overweight and obesity is not restricted to adults. America's youth are also experiencing epidemic rates of overweight and …

Priam's Lament: The Intersection Of Law And Morality In The Right To Burial And Its Need For Recognition In Post-Katrina New Orleans, Sarah Tomkins

University of the District of Columbia Law Review

Priam's lament might resound with those of us who saw certain images after Hurricane Katrina struck New Orleans three short years ago: bodies of beloved mothers, fathers, sisters, and brothers dangling from house rafters and left to rot on street corners and in basements for months. The remaining unidentified victims were interred last summer at a new memorial, after spending the three years since Hurricane Katrina in a storage facility.3 How could this happen? In America, we might not expect the intercession of gods, but we do expect our government to set reasonable limits on human suffering. Were there just …

Nonparametric Incidence Estimation From Prevalent Cohort Survival Data, Marco Carone, Masoud Asgharian, Mei-Cheng Wang

COBRA Preprint Series

Incidence is an important epidemiologic concept particularly useful in assessing an intervention, quantifying disease risk, and planning health resources. Incident cohort studies constitute the gold-standard in estimating disease incidence. However, due to material constraints, data are often collected from prevalent cohort studies whereby diseased individuals are recruited through a cross-sectional survey and followed forward in time. We discuss the identifiability of measures of incidence in the context of prevalent cohort survival studies and derive nonparametric maximum likelihood estimators and their asymptotic properties. The proposed methodology accounts for calendar-time and age-at-onset variation in disease incidence while also addressing common complications arising …

Comparison Of Replication-Competent, First Generation, And Helper-Dependent Adenoviral Vaccines, Eric A. Weaver, Pramod N. Nehete, Stephanie S. Buchl, Julien S. Senac, Donna Palmer, Philip Ng, K. Jagannadha Sastry, Michael A. Barry

Nebraska Center for Virology: Faculty Publications

All studies using human serotype 5 Adenovirus (Ad) vectors must address two major obstacles: safety and the presence of pre-existing neutralizing antibodies. Helper-Dependent (HD) Ads have been proposed as alternative vectors for gene therapy and vaccine development because they have an improved safety profile. To evaluate the potential of HD-Ad vaccines, we compared replication-competent (RC), first-generation (FG) and HD vectors for their ability to induce immune responses in mice. We show that RC-Ad5 and HD-Ad5 vectors generate stronger immune responses than FG-Ad5 vectors. HD-Ad5 vectors gave lower side effects than RC or FG-Ad, producing lower levels of tissue damage and …

Migrations Forced By Violence: The Colombian Case, G Gómez, A Astaiza, M C. Minayo

English

Objective: To show an overview of the phenomenon of forced migration due to violence in the world, and to discuss the specifics of this issue in the Colombian experience.

Bruesewitz V. Wyeth Inc

2009 Decisions

USDC for the Eastern District of Pennsylvania

Visualizing Antigen-Specific And Infected Cells In Situ Predicts Outcomes In Early Viral Infection, Qingsheng Li, Pamela J. Skinner, Sang-Jun Ha, Lijie Duan, Teresa L. Mattila, Aaron Hage, Cara White, Daniel L. Barber, Leigh O'Mara, Peter J. Southern, Cavan S. Reilly, John V. Carlis, Christopher J. Miller, Rafi Ahmed, Ashley T. Haase

Qingsheng Li Publications

In the early stages of viral infection, outcomes depend on a race between expansion of infection and the immune response generated to contain it. We combined in situ tetramer staining with in situ hybridization to visualize, map, and quantify relationships between immune effector cells and their targets in tissues. In simian immunodeficiency virus infections in macaques and lymphocytic choriomeningitis virus infections in mice, the magnitude and timing of the establishment of an excess of effector cells versus targets were found to correlate with the extent of control and the infection outcome (i.e., control and clearance versus partial or poor control …

Multi-Species Influenza Models With Recombination, Brian John Coburn

Open Access Dissertations

Avian influenza strains have been proven to be highly virulent in human populations, killing approximately 70 percent of infected individuals. Although the virus is able to spread across species from birds-to-humans, some strains, such as H5N1, have not been observed to spread from human-to-human. Pigs are capable of infection by both avian and human strains and seem to be likely candidates as intermediate hosts for co-infection of the inter-species strains. A co-infected pig potentially acts as a mixing vessel and could produce a new strain as a result of a recombination process. Humans could be immunologically naive to these new …

Washington University Record, March 26, 2009

Washington University Record

No abstract provided.

What Do Young Adults Know About The Hiv/Aids Epidemic? Findings From A Population Based Study In Karachi, Pakistan., Syed Farid-Ul-Hasnain, Eva Johansson, Gunilla Krantz

Community Health Sciences

Background: HIVAIDS is spreading globally, hitting the younger generations. In Pakistan, the prevalence of HIV in high-risk subpopulations is five per cent or higher. This poses a serious threat of a generalised epidemic especially among the younger population. In the wake of HIVAIDS epidemic this is worrying as a well informed younger generation is crucial in restricting the spread of this epidemic. This study investigated Pakistani young adults' (male and female) knowledge and awareness of the HIV/AIDS disease. Methods: A population-based, cross-sectional study of 1,650 male and female adults aged 17-21 years living in Karachi was conducted using a structured …

Aggression And Its Consequences In Nursing: A More Complete Story By Adding Its Social Context, Liu-Qin Yang

USF Tampa Graduate Theses and Dissertations

Using a 471-case nursing sample, the current study examined the direct and indirect relationships between workplace aggression (including physical and psychological) against nurses and their health and safety consequences. Specifically, physical and psychological aggression nurses experienced were related to their job dissatisfaction, turnover intention, physical symptoms, injuries and exposure to contagious disease directly and/or indirectly through their emotional strain (irritation, anxiety, and depression). In addition, my findings demonstrated that stronger violence prevention climate (i.e., good prevention practices/response and low pressure for unsafe practices) was related to less frequent violence and psychological aggression incidents nurses experienced. Also, my results indicated significant …