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Time-Frequency Analysis Of Intracardiac Electrogram, Erik Brockman

Master's Theses

The Cardiac Rhythm Management Division of St. Jude Medical specializes in the development of implantable cardioverter defibrillators that improve the quality of life for patients diagnosed with a variety of cardiac arrhythmias, especially for patients prone to sudden cardiac death. With the goal to improve detection of cardiac arrhythmias, this study explored the value in time-frequency analysis of intracardiac electrogram in four steps. The first two steps characterized, in the frequency domain, the waveforms that construct the cardiac cycle. The third step developed a new algorithm that putatively provides the least computationally expensive way to identifying cardiac waveforms in the …

Preparation For Nerve Membrane Potential Readings Of A Leech, Laboratory Setup And Dissection Process, Jason Patrick Caulfield

Master's Theses

A well documented laboratory setup, leech preparation process, and bio-potential data recording process are needed. Repeatability and quality data recordings are essential and thus dictate the requirements of the laboratory setup and processes listed above. Advances in technology have both helped and hindered this development. While very precise equipment is required to record the low voltage bio-potentials, noisy electronic equipment and wires surrounding the work area provide high levels of interference. Proper laboratory setup and data recording processes, however, limit the unwanted interference. Quality data can only be recorded from a properly handled and prepared leech subject. Proper setup and …

Preparation And Characterization Of Electrospun Poly(D, L-Lactide-Co-Glycolide) Scaffolds For Vascular Tissue Engineering And The Advancement Of An In Vitro Blood Vessel Mimic, Tiffany Richelle Pena

Master's Theses

PREPARATION AND CHARACTERIZATION OF ELECTROSPUN POLY(D,L-LACTIDE-CO-GLYCOLIDE) SCAFFFOLDS FOR VASCULAR TISSUE ENGINEERING AND THE ADVANCEMENT OF AN IN VITRO BLOOD VESSEL MIMIC

Tiffany Richelle Peña

Currently, an estimated 1 in every 3 adult Americans are affected by one or more cardiovascular complications. The most common complication is coronary artery disease, specifically atherosclerosis. Outcomes of balloon angioplasty treatments have been significantly improved with the addition of drug eluting stents to the process. Although both bare metal and drug eluting stents have greatly increased the effectiveness of angioplasty and decreased the occurrence of restenosis, several complications still exist. For this reason, the stent …

Scientific Divers Quantify First Known Outbreaks Of Cold-Water Coral Disease, J Hall-Spencer, C Munn, K Hiscock

School of Biological and Marine Sciences

Coral diseases are widely reported in the tropics but the first incidence of cold-water coral disease was not noted until 2002 when divers recorded an outbreak at 10-28 m depth off Lundy in a NE Atlantic marine protected area. The seafan Eunicella verrucosa exhibited coenchyme necrosis and subsequent diving surveys of >600 colonies at 13 sites since revealed that disease outbreaks were widespread in SW England to depths of 50 m from 2003-2008, possibly caused by infection by Vibrio bacteria at high temperatures.

Undergraduate Curriculum And Academic Policy Committee Minutes, May 13, 2009

Undergraduate Curriculum and Academic Policy Committee Minutes

Minutes from the Wright State University Faculty Senate Undergraduate Curriculum and Academic Policy Committee meeting held on May 13, 2009.

Head And Neck Embryology: An Overview Of Development, Growth And Defect In The Human Fetus, Allison Baylis

Honors Scholar Theses

The purpose of this research is to explore the growth and formation of the head and neck from embryological development through puberty in order to understand how this knowledge is necessary for the development of dental and medical treatments and procedures. This is a necessary aspect of the medical and dental school curriculum at the University of Connecticut Health Center Schools of Medicine and Dental Medicine that needs to be incorporated into the current study of embryology for first-year students. Working with Dr. Christine Niekrash, D.M.D, this paper will cover the embryology and growth of the head, face and oral …

Knockdown Of Kiaa0319 Reduces Dendritic Spine Density, Daniel Young Kim

Honors Scholar Theses

Developmental Dyslexia is a reading disorder that affects individuals that possess otherwise normal intelligence. Until the four candidate dyslexia susceptibility genes were discovered, the cause of cortical malformations found in post mortem dyslexic brains was unclear. Normal brain development is crucial for the proper wiring of the neural circuitry that allow an individual to perform cognitive tasks like reading. For years, familial and twin studies have suggested that there was a genetic basis to the causation of dyslexia. Kiaa0319 was among the candidate dyslexia susceptibility genes that were ascertained. KIAA0319 is located on Chromosome 6p22.2-22.3 and has been found to …

Minimum Criteria For Dna Damage-Induced Phase Advances In Circadian Rhythms, Christian I. Hong, Judit Zámborszky, Attila Csikász-Nagy

Dartmouth Scholarship

Robust oscillatory behaviors are common features of circadian and cell cycle rhythms. These cyclic processes, however, behave distinctively in terms of their periods and phases in response to external influences such as light, temperature, nutrients, etc. Nevertheless, several links have been found between these two oscillators. Cell division cycles gated by the circadian clock have been observed since the late 1950s. On the other hand, ionizing radiation (IR) treatments cause cells to undergo a DNA damage response, which leads to phase shifts (mostly advances) in circadian rhythms. Circadian gating of the cell cycle can be attributed to the cell cycle …

May 5, 2009 Aasu Graduate Affairs Committee Minutes, Armstrong Atlantic State University

Armstrong Office of the Registrar: Graduate Affairs Committee Minutes (Archived)

May 5, 2009 AASU Graduate Affairs Committee Minutes

Chips 2009, University Of The Pacific Arthur A. Dugoni School Of Dentistry

Dental School Yearbooks

Yearbook for the University of the Pacific Arthur A. Dugoni School of Dentistry, originally the College of Physicians and Surgeons

An Investigation Of Cardiac Dynamics And Substrate Metabolism In An Animal Heart Failure Model, Anna Stanhewicz

Senior Honors Projects

Heart failure (HF) is a condition in which the working heart is unable to meet the blood flow demands of the body. It is the leading cause of early death in the United States and is a progressive, debilitating disease that presently, can only be detected in late, irreversible stages. The progression of HF is complex and poorly understood, involving a number of molecular mechanisms. It is characterized by a complex of symptoms including cardiac hypertrophy and a shift in myocardial substrate utilization, all leading to reduced pumping efficiency of the heart and decreased systemic blood flow. In HF, the …

Enhancing Bacterial Expression Of Mammalian Gprotein Coupled Receptors The Creation Of A Proteorhodopsin‐Bovine Rhodopsin Chimera, Chauncey Brown Jr.

Renée Crown University Honors Thesis Projects - All

Bovine (cow) rhodopsin is a 7‐transmembrane (7TM), lightabsorbing protein located in rod cells. It is activated by the photoisomerization of retinal, a Vitamin A derivative. This light‐triggered reaction activates the G‐Protein Coupled Receptor (GPCR), resulting in a signaling cascade within the cell. When previously cloned in an E. coli expression vector in the Braiman Lab, bovine rhodopsin expression was not successful, possibly due to E. coli’s lack of recognition of the foreign Nterminus portion of the protein, which may be a prerequisite for proper folding and insertion into the membrane. Our proposed solution is to create a chimera protein, replacing …

A Study Of A Proposed Molecular Mechanism For Idiopathic Cases Of Hypertension: Detection Of Aldosterone-Receptor Complex At Period Homolog 1 (Per1) Promoter Using Chromatin Immunoprecipitation (Chip), Brent Colin Turner

Departmental Honors & Graduate Capstone Projects

Hypertension severely affects the quality and quantity of life of those afflicted with the disease. In most cases where the cause is known, hypertension is due to an abnormally high sodium condition; however, the mechanism by which this occurs is unknown. This phenomenon is particularly detrimental to patients considered to be non-dippers, experiencing no nocturnal dip in blood pressure. A proposed molecular mechanism for the relationship between dipping and sodium concentration involves the regulation of the circadian gene Period 1 homolog (Per1) by aldosterone and was studied by using chromatin immunoprecipitation (ChIP). This technique results in an enrichment of the …

An Examination Of Body Composition Measurement Methods In Children, Robert Kaplan

UNLV Theses, Dissertations, Professional Papers, and Capstones

Introduction . Body-composition methods include underwater weighing (UWW), skinfold thickness (SKF), bioelectrical impedance (BIA), and the BOD POD. Although these techniques are used routinely, each has its inherent limitations, especially in children. Purpose . The purpose of this study was to examine the various methods of body composition in children. Methods . The body composition of 7 boys between the ages of 12-14 (13.1 +/- 1.1 years) was determined using the BOD POD, UWW, SKF, and BIA. Results . Percent body fat estimated from the BOD POD (21.9 +/- 7.8%BF) was not significantly different than the estimated percent fat from …

Breaking The Spell: Developing A New Generation Of Porphyrins For Treating Cerebral Tumors, Ryan Harrison Gray

Honors Capstones

No abstract provided.

Impact Of Flash Animation In Learning Concepts Of Matter Among Elementary Students, Rhodora S. Santos

Theses and Dissertations - UTB/UTPA

This study examines the instructional effect of flash animation on students' achievement in learning specific concepts of matter. The subjects used in this study were 5th-grade students of the researcher from Dan Ramirez Elementary. Each class or section of these students was randomly assigned as the control group (n = 20) and the experimental group (n =20). The subjects in the control group were exposed to traditional textbook reading while the subjects in the experimental group were exposed to flash animation. To measure the students' achievement from the concepts learned, a pre-test and a post test were both administered to …

Central Florida Future, Vol. 41 No. 43, April 24, 2009

Central Florida Future

UnCover Fridays; Sexy safety; Plus: Future wrap up; Turn up the heat; STDs rising at UCF; Getting tested; Sexual health; Psych course teaches ins and outs of sexual behavior.

Clock-Cancer Connection In Non-Hodgkin’S Lymphoma: A Genetic Association Study And Pathway Analysis Of The Circadian Gene Cryptochrome 2, Richard G. Stevens

UCHC Articles - Research

Circadian genes have the potential to influence a variety of cancer-related biological pathways, including immune regulation, which may influence susceptibility to non-Hodgkin’s lymphoma (NHL). However, few studies have examined the role of circadian genes in lymphomagenesis. The current study examined Cryptochrome 2 (CRY2), a core circadian gene and transcriptional repressor, as a potential circadian biomarker for NHL. We first performed genetic association analyses of tagging SNPs in CRY2 and NHL risk using DNA samples from a population-based case-control study (N= 455 cases and 527 controls). Three SNPs were found to be significantly associated with risk of NHL when …

Animals And The Problem Of Evil In Recent Theodicies, Mark Maller

Philosophy Scholarship

This paper critically evaluates the theodicies of John Hick, Richard Swinburne and process theism regarding animal suffering and evils. The positions of Hick and Swinburne are based on false empirical assumptions, e.g., animals do not suffer. Process theism’s claim that God is not omnipotent is an unsatisfactory answer inconsistent with the traditional concept of God. These positions cannot fully explain the mass suffering and unnecessary deaths of animals throughout time. My positive position is that God’s putative love for all sentient beings does not necessarily entail that he loves every individual human and animal. Humans do not interfere with the …

Contact Point, Arthur A. Dugoni School Of Dentistry

Contact Point

No abstract provided.

Will Teachers Shed Their First Amendment Rights At The Schoolhouse Gate?, Jonel Newman

University of Miami Law Review

No abstract provided.

Creation Care And The Christian, Jo Ann Davidson

Faculty Publications

No abstract provided.

Chapter Vi, Pp. 106-118

The Jefferson Medical College of Philadelphia, Benefactors, alumni, hospital etc. Its founders, officers, instructors, 1826--1904 A HISTORY (Volume 1)

No abstract provided.

Automatic Detection Of Child Pornography, Glen Thompson

Australian Digital Forensics Conference

Before the introduction of the internet, the availability of child pornography was reported as on the decline (Jenkins 2001). Since its emergence, however, the internet has made child pornography a much more accessible and available means of trafficking across borders (Biegel 2001; Jenkins 2001; Wells, Finkelhor et al. 2007). The internet as it is at present is made up of a vast array of protocols and networks where traffickers can anonymously share large volumes of illegal material amongst each other from locations with relaxed or non-existent laws that prohibit the possession or trafficking of illegal material. Likewise the internet is …

Cwu Faculty Senate Minutes - 03/11/09, Janet Shields

Faculty Senate Minutes

These are the official Central Washington University Faculty Senate minutes for the 03/11/09 meeting.

Faculty Senate Motion 014.08/09: University Curriculum Committee, Armstrong Atlantic State University

Armstrong Faculty Senate: Bills, Motions & Resolutions (Archived)

Faculty Senate Motion 014.08/09: University Curriculum Committee

March 9, 2009 Aasu Faculty Senate Minutes, Armstrong State University

Armstrong Faculty Senate: Minutes (Archived)

March 9, 2009 AASU Faculty Senate Minutes

Heterogeneity Effects In Plutonium Contaminated Soil, Orlando M. Chaparro

Theses and Dissertations

In 1960 at the McGuire Air Force Base, New Egypt, New Jersey a helium tank ruptured causing a fire to ignite a nearby nuclear tipped Boeing Michigan Aeronautical Research Center (BOMARC) missile. During the fire the weapons grade plutonium (Pu- 239, Pu-240, and Pu-241) ignited and was released into the surrounding area, due to both firefighting efforts, where high pressure water was used to put out the fire, as well as smoke that deposited plutonium as oxidized particles in the surrounding area (Cicotte, 2007). This study investigates the heterogeneity of the distributed plutonium contamination in the McGuire Air Force Base …

Chapter 7- Eminent Jefferson Professors, Pp. 231-386

Legend and Lore: Jefferson Medical College

No abstract provided.

Exercise-And Hypoxia-Induced Anaerobic Metabolism And Recovery: A Student Laboratory Exercise Using Teleost Fish, Bernard Rees

Biological Sciences Faculty Publications

Anaerobic metabolism is recruitedin vertebrates under conditions of intense exercise or lowered environmental oxygen availability (hypoxia), typically resulting in the accumulation of lactate in blood and tissues. Lactate will be cleared over time after the reoxygenation of tissues, eventually returning to control levels. Here, we present a laboratory exercise developed as part of an upper-level vertebrate physiology class that demonstrates the effects of exercise and hypoxia exposure on blood lactate in fish and the subsequent decrease in lactate during recovery. Typically, the results obtained by students demonstrate that both treatments cause significant increases in blood lactate concentrations (two to three …