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2008

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Ot 520 Old Testament Introduction, Edwin C. Hostetter Jan 2008

Ot 520 Old Testament Introduction, Edwin C. Hostetter

Syllabi

Bernhard W. Anderson, Contours of Old Testament Theology, with the assistance of Steven Bishop (Minneapolis: Fortress Press, 1999) John J. Collins, A Short Introduction to the Hebrew Bible (Minneapolis: Fortress Press, 2007) John H. Hayes and Carl R. Holladay, Biblical Exegesis: A Beginner's Handbook, 3d ed. (Louisville: Westminster John Knox Press, 2007) Paul R. House, Old Testament Survey (Nashville: Broadman & Holman Publishers, 1992)

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Effects Of Hexosamine Biosynthesis On An In Vitro Model Of Cardiacischemia, Voraratt Champattanachai Jan 2008

Effects Of Hexosamine Biosynthesis On An In Vitro Model Of Cardiacischemia, Voraratt Champattanachai

All ETDs from UAB

Increased levels of protein O-linked-N-acetylglucosamine (O-GlcNAc) have been correlated with increased cell survival following stress. Therefore the goal of this study was to determine whether enhanced flux through the hexosamine biosynthesis pathway (HBP), which leads to elevated levels of O-GlcNAc, improved the tolerance of isolated neonatal rat ventricular myocytes (NRVMs) to ischemia/reperfusion (I/R) injury. NRVMs were exposed to hypoxic medium for 4 hours, followed by oxygenated complete medium for 16 hours. Acute treatment with 5 mM glucosamine showed an increase in viability and decreased both necrosis and apoptosis following I/R. Glucosamine increased O-GlcNAc levels maximally at 2 hours and went …

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The Relationship Of Medical Homeness To The Quality Of Life Of Mothers Of Children With And Without Special Health Care Needs, Cynthia G. Cortes Jan 2008

The Relationship Of Medical Homeness To The Quality Of Life Of Mothers Of Children With And Without Special Health Care Needs, Cynthia G. Cortes

All ETDs from UAB

A cross-sectional study was conducted to investigate the relationship of child, family, and medical home status to quality of life for mothers of children with and without special health care needs. Mothers of children with (n=100) and without (n=80) special health care needs, completed a questionnaire at a children’s hospital in the southeastern United States focusing on the child, family, and medical home and maternal quality of life. Standardized instruments were used to measure quality of life (SF-36) and social support (Social Support Questionnaire). Non-standardized instruments used in other research were incorporated into the maternal questionnaire. Logistic and linear regression …

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Structural And Functional Properties Of Human Αa-Crystallin, Jose Mauro Chaves Jan 2008

Structural And Functional Properties Of Human Αa-Crystallin, Jose Mauro Chaves

All ETDs from UAB

The three specific aims of the project were: (1) compare effects of deamidation alone (i.e., αA-N101D, αA-N123D, αA-N101/123D), truncation alone (αA-NT mutant [deletion of residue no. 1-63], or αA-CT mutant [deletion of residue no. 140-173]), or both truncation plus deamidation on structural and functional properties of human lens αA-crystallin; (2) identify components of complexes in the water soluble-high molecular weight (WS-HMW) proteins of normal aging and cataractous human lenses; and (3) determine interactions among WT-αA, αA-NT and αA-CT crystallin species with filensin and phakinin (beaded filament proteins) in vitro. The comparative structural and functional differences between αA-deamidated and/or truncated mutants …

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The Reproductive Cycle Of Lytechinus Variegatus (Echinodermata: Echinoidea) From The Florida Panhandle, Adele Cunningham Jan 2008

The Reproductive Cycle Of Lytechinus Variegatus (Echinodermata: Echinoidea) From The Florida Panhandle, Adele Cunningham

All ETDs from UAB

The range of the regular echinoid Lytechinus variegatus extends from the Carolinas along the US Atlantic coast to Brazil. To our knowledge, the present study is the northernmost study to examine histology of the reproductive cycle of Lytechinus variegatus. From April 2001 to September 2003, at intervals of about 4-6 weeks, L. variegatus with an average diameter of 45 mm were collected at Eagle Harbor in St. Joseph’s Bay, Florida.. A staging system for gamete development and maturation based on histology of the gonad was devised for female and male L. variegatus. Histology indicated a period of nutrient storage and …

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Microbial Biofilm Attachment To Caenorhabditis Elegans, Kevin Drace Jan 2008

Microbial Biofilm Attachment To Caenorhabditis Elegans, Kevin Drace

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The closely related bacterial species Xenorhabdus nematophila, Yersinia pestis and Y. pseudotuberculosis make biofilms capable of adhering to the head of the model nematode Caenorhabditis elegans. Y. pestis uses biofilms to block the digestive tract of its vector, the flea, in order to enhance its efficiency of transmission. I investigated the role of biofilms in X. nematophila and found that, like its Yersinia sp. counterparts, production of biofilm requires a four-gene operon: hmsHFRS. X. nematophila is an insect pathogen and an obligate symbiont of the nematode Steinernema carpocapsae. However, an X. nematophila hmsH mutant that failed to make biofilms on …

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Examining Pre-Service Instructors' Use Of Powerpoint Based On Pre-Service Students' Perceptions: A Mixed Methods Study, Jennifer Fritschi Jan 2008

Examining Pre-Service Instructors' Use Of Powerpoint Based On Pre-Service Students' Perceptions: A Mixed Methods Study, Jennifer Fritschi

All ETDs from UAB

This study explored pre-service instructors’ use of PowerPoint based on pre-service students’ perceptions, and it identified pre-service students’ perceptions of the efficacy of specific elements of PowerPoint design and delivery. The effectiveness of various elements of PowerPoint design and delivery was based on an extensive literature review and was framed on the Cognitive Theory of Multimedia (Mayer, 2000). The findings of the study identified pre-service instructors’ practices and pre-service students’ perceptions of the effectiveness of specific elements of design and delivery and were then compared with what research and expert literature purported were effective. This one year study was conducted …

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Phenomenological Study: What Are Pre-Kindergarten Teachers' Lived Experiences With Children Identified With Conduct Disorder, Oppositional Defiance Disorder, And Attention-Deficit Hyperactivity Disorder In The Southeastern United States?, Danna Benefield Jones Jan 2008

Phenomenological Study: What Are Pre-Kindergarten Teachers' Lived Experiences With Children Identified With Conduct Disorder, Oppositional Defiance Disorder, And Attention-Deficit Hyperactivity Disorder In The Southeastern United States?, Danna Benefield Jones

All ETDs from UAB

To date, a vast amount of research has been conducted on disruptive behavior dis-orders such as conduct disorder (CD), oppositional defiance disorder (ODD), and atten-tion deficit hyperactivity disorder (ADHD. However, a paucity of research exists in spe-cific areas such as how teachers’ handle students diagnosed with these disorders. The cur-rent situation in pre-kindergarten may undermine the ability of these students to succeed in the school system. This is seen in the fact that a large number of these students are removed from pre-kindergarten programs across the United States (Webster-Stratton, Reid, & Hammond, 2004). Understanding pre-kindergarten teachers’ lived experiences in handling …

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Getting It Right: A Multiple Case Study Of Exemplary Ari Schools, Anne Knowlton Jan 2008

Getting It Right: A Multiple Case Study Of Exemplary Ari Schools, Anne Knowlton

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This qualitative multiple case study described the integration of the Alabama Reading Initiative (ARI) in three exemplary, yet very dissimilar elementary schools. Studies have shown that ARI has been successful in improving reading in Alabama schools. This study addressed the gap in the literature regarding exactly how this improvement has taken place. An urban school, a rural school, and a suburban school, which have reached an overall benchmark level of 90% or higher, were used for this study. Participants for the research included the principal, reading coach, and kindergarten through third grade teachers at each site. Data were collected in …

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Role Of The Gm/Gn Glycoprotein Complex In The Final Assembly And Egress Of The Human Cytomegalovirus (Hcmv), Magdalena Anna Krzyzaniak Jan 2008

Role Of The Gm/Gn Glycoprotein Complex In The Final Assembly And Egress Of The Human Cytomegalovirus (Hcmv), Magdalena Anna Krzyzaniak

All ETDs from UAB

HCMV consists of a dsDNA genome enclosed by, an icosahedral capsid surrounded by a layer of tegument proteins; the virion structure is enclosed in a lipid envelope rich in virus expressed glycoproteins. The HCMV envelope contains an incompletely defined number of glycoproteins. The glycoprotein M (gM) and glycoprotein N (gN) form a gM/gN protein complex which is the most abundant protein component of the HCMV envelope. Recent studies have indicated that deletion of the viral gene encoding either gM or gN is lethal for HCMV. The gM C-terminal cytoplasmic tail (gM-CT) revealed an acidic cluster and a tyrosine-based trafficking motifs. …

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English Oral Language Usage Of Caregivers In Selected Orphanages Of Eastern India: A Phenomenological Study, Constance Diane Lawrence Jan 2008

English Oral Language Usage Of Caregivers In Selected Orphanages Of Eastern India: A Phenomenological Study, Constance Diane Lawrence

All ETDs from UAB

The purpose of this research was to determine the situation and frequency of the use of English oral language by caregivers with young children who are orphaned. Two orphan centers in the state of West Bengal, India were chosen for this study. Interviews and observations of caregivers were used to determine the caregivers’ self-perceptions of their own fluency in English and the amount of English utilized by the caregivers with children in the orphan centers. A total of twelve caregivers participated in this study. Seven caregivers, three full-time and four part-time, three females and four males, participated at Center One. …

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Punctal Occlusion Impact On Tear Film Immuno-Regulatory Proteins Measured By Cytometric Bead-Based Assay, Martin W. Lafrance Jan 2008

Punctal Occlusion Impact On Tear Film Immuno-Regulatory Proteins Measured By Cytometric Bead-Based Assay, Martin W. Lafrance

All ETDs from UAB

PURPOSE: This study compares vendor reagents used for cytometric bead-based assay (CBA) of cytokines in human tears and validates a protocol for use in evaluating punctal occlusion, a treatment for keratoconjunctivitis sicca. It has been proposed that punctal occlusion may alter tear cytokine concentrations based on the facts that: (1) tear clearance, a measure of the balance between tear production and elimination, declines following occlusion and (2) reduced tear clearance and increased levels of pro-inflammatory tear cytokines are correlated in dry eye patients. This study compares tear clearance values and the level of 24 tear cytokines measured by CBA following …

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Transcriptional Regulation Of Cd40 And Class Ii Mhc Molecules In Macrophages And Microglia By Statins, Sun Jung Lee Jan 2008

Transcriptional Regulation Of Cd40 And Class Ii Mhc Molecules In Macrophages And Microglia By Statins, Sun Jung Lee

All ETDs from UAB

Microglia/macrophages are the main intrinsic immune effector cells and the first cell types that respond to a variety of CNS injures. They have important functions including secretion of cytokines/chemokines and antigen presentation, thereby regulating immune responses. Interferon-γ (IFN-γ) is a cytokine involved in many aspects of the immune response, and activates microglia/macrophages to express cell surface antigens such as class II MHC, and co-stimulatory molecules such as CD40. CD40 and class II MHC molecules play a critical role in immune reactivity such as antigen presentation and subsequent T cell activation. However, aberrant CD40 and class II MHC expression have been …

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The Induction Of First Year And Transferring Elementary School Teachers: A Multiple Case Study, Patricia L. Lequier Jan 2008

The Induction Of First Year And Transferring Elementary School Teachers: A Multiple Case Study, Patricia L. Lequier

All ETDs from UAB

This qualitative, multiple case study explored the experiences of elementary teachers and principals participating in school induction processes. The staggering rates at which new teachers are leaving the profession, coupled with high rates of teacher attrition, teacher retirements, and increases in student enrollment formed the impetus for this study. These factors have collectively contributed to the nation’s crucial demand for close to two million teachers. In an effort to increase the retention rate of new teachers, schools across the nation have implemented teacher induction processes. Teacher induction processes focus on providing support for teachers in their transition from their roles …

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Interim Monitoring Efficacy, Safety And Futility In Phase Iii Clinical Trials, Qing Li Jan 2008

Interim Monitoring Efficacy, Safety And Futility In Phase Iii Clinical Trials, Qing Li

All ETDs from UAB

Phase III trials often have both efficacy and safety outcomes. Sometimes the safety outcomes are closely associated with the efficacy outcomes. We sought to find a statistical method to treat both efficacy and safety outcomes as bivariate primary outcomes and set up stopping rules at interim stages based on the following criteria: (1) greater safety; (2) greater efficacy; (3) futility. We first examined the internal pilot design to adjust sample size for clinical trials with a bivariate response (efficacy and safety). Three nuisance parameters (two variances and correlation) need to be considered when doing sample size recalculation for the internal …

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The Au-Rich Element Mrna Decay-Promoting Activity Of Brf1 Is Regulated By Mitogen-Activated Protein Kinase Activated Protein Kinase 2, Sushmit Maitra Jan 2008

The Au-Rich Element Mrna Decay-Promoting Activity Of Brf1 Is Regulated By Mitogen-Activated Protein Kinase Activated Protein Kinase 2, Sushmit Maitra

All ETDs from UAB

Regulated mRNA decay is a highly important process for the tight control of gene expression. Inherently unstable mRNAs contain AU-rich elements (AREs) in the 3’ untranslated regions that direct rapid mRNA decay by interaction with decay-promoting ARE-binding proteins (ARE-BPs). The decay of ARE-containing mRNAs is regulated by signaling pathways, which are believed to directly target ARE-BPs. Here, we show that BRF1 involved in ARE-mediated mRNA decay (AMD) is phosphorylated by MAPK-activated protein kinase 2, MK2. In vitro kinase assays using different BRF1 fragments suggest that MK2 phosphorylates BRF1 at four distinct sites, S54, S92, S203, and an unidentified site at …

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The Physical And Mental Health Of Spouse Caregivers In Dementia: Finding Meaning As A Mediator Of Burden, Susan M. Mclennon Jan 2008

The Physical And Mental Health Of Spouse Caregivers In Dementia: Finding Meaning As A Mediator Of Burden, Susan M. Mclennon

All ETDs from UAB

The purpose of this study was to examine the effect of caregiver burden on the physical and mental health of caregivers of spouses with dementia and to determine if finding meaning through caregiving mediated the relationship between burden and health. This was a cross-sectional, correlational study in a convenience sample of 84 community-residing spouse caregivers of adults with dementia recruited from North- Central Florida. Measures included the Zarit Burden Interview, the Finding Meaning through Caregiving Scale, and the Medical Outcomes Short Form-36, version 2. Data analyses consisted of descriptive, correlational, and standard multiple regression statistical methods. The sample consisted of …

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How Do Federal Programs Coordinators Navigate Under No Child Left Behind?: A Case Study Of Alabama, Donald R. Mcpherson Jan 2008

How Do Federal Programs Coordinators Navigate Under No Child Left Behind?: A Case Study Of Alabama, Donald R. Mcpherson

All ETDs from UAB

This qualitative case study described the experiences of federal programs coordinators in Alabama as they implemented the No Child Left Behind (NCLB) Act of 2001. Furthermore, this study identified a significant gap in research and other published literature that addresses the ongoing struggles faced by federal programs coordinators as they lead their colleagues and respective school systems in efforts to implement and ultimately comply with the numerous and stringent regulations regarding NCLB. The study brought to light and pinpointed a multitude of difficult and time-consuming tasks relating to adherence to NCLB guidelines. The researcher incorporated the professional perspectives and experiences …

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Modulation Of Transforming Growth Factor (Tgf)-Ss1 And Its Implications In Breast Cancer Metastasis, Lakisha Dionne Moore Jan 2008

Modulation Of Transforming Growth Factor (Tgf)-Ss1 And Its Implications In Breast Cancer Metastasis, Lakisha Dionne Moore

All ETDs from UAB

Overexpresssion of transforming growth factor (TGF)-β has been implicated in promoting immune suppression, tumor angiogenesis, tumor cell migration, and invasion in many cancers including carcinoma of the breast. Thus, targeted downregulation of TGF-β1 expression in breast cancer in situ and determination of its implications potentially could provide new treatment approaches for disease management. siRNA constructs targeting TGF-β1 were validated and used to develop clonal derivatives of the MDA-MB-435 metastatic breast cancer cell line. Inhibition of TGF-β1 expression in MDA-MB-435 cells showed decrease in migration and invasion in vitro with an increase in proliferation. In vivo analysis indicated a 90% decrease …

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The Role Of Centaurin Alpha-1 In The Regulation Of Neuron Al Differentiation, Carlene Drucilla Moore Jan 2008

The Role Of Centaurin Alpha-1 In The Regulation Of Neuron Al Differentiation, Carlene Drucilla Moore

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In the nervous system, PI 3-kinase has been implicated in neuronal differentiation. My studies have focused on a candidate neuronal PI 3-kinase target centaurin alpha-1, which binds PtdIns(3,4,5)P3, and is an Arf6 GAP. Centaurin alpha-1 is localized in dendrites, dendritic spines and synapses, and is required for neuronal differentiation and spine morphogenesis. In dissociated neuronal cultures, expression of centaurin alpha-1 enhances dendritic branching, and increases dendritic filopodia, lamellipodia and spine-like protrusions. Expression of centaurin alpha-1 GAP inactive mutant or knocking down centaurin alpha-1 levels using siRNA leads to inhibition of dendritic outgrowth and branching. Manipulations of centaurin alpha-1 also disrupt …

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Relationships Among Anger, Patterns Of Anger Expression And Blood Pressure, Glucose, And Cortisol In Overweight School-Aged Children, Kimberly Nichols Jan 2008

Relationships Among Anger, Patterns Of Anger Expression And Blood Pressure, Glucose, And Cortisol In Overweight School-Aged Children, Kimberly Nichols

All ETDs from UAB

Overweight and obesity in school-aged children have become a major health issue. With overweight and obesity, children have increased risk of developing elevated blood pressure readings, glucose levels, and cortisol. Trait anger and patterns of anger expression have been shown to contribute to the elevations of blood pressure, glucose and cortisol in normoweight children and overweight adolescents. However, little research has been done with overweight school-aged children. The purpose of this study was to examine the relationships among trait anger and each of the patterns of anger expression (anger-suppression, anger-out, and anger-reflection/control) and blood pressure, glucose, and cortisol in overweight …

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Transition Metal Complexes Of Bis(Phosphorus) Donor Ligands Derived From Multifunctional Diols: Synthesis, Isomerization, Cation Binding, And Catalysis., Samuel Britt Owens Jan 2008

Transition Metal Complexes Of Bis(Phosphorus) Donor Ligands Derived From Multifunctional Diols: Synthesis, Isomerization, Cation Binding, And Catalysis., Samuel Britt Owens

All ETDs from UAB

In Chapter 1, the metallacrown ethers cis-[PdCl2{Ph2P(CH2CH2O)3CH2CH2PPh2-P,P’}] and trans-PtCl2{Ph2P(CH2CH2O)3CH2CH2PPh2-P,P’} were studied. These metallacrown ethers are ideal candidates for the study of the kinetics and thermodynamics of cis-trans isomerizations because of their highly flexible backbones. We have carried out these studies using 31P NMR spectroscopy, and the equilibrium constants and thermodynamic and kinetic parameters for these reactions are reported. Chapter 2 of this dissertation explores the cation binding ability of the tartaric acid backbone proposed as the building block for the ligands developed herein for the hydroformylation of styrene. Binding studies and crystallographic analysis confirmed that incorporating the tartaric acid backbone …

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Children's Prenumerical Quantification Of Time, Kelly A. Russell Jan 2008

Children's Prenumerical Quantification Of Time, Kelly A. Russell

All ETDs from UAB

Time cannot be seen or physically examined, and philosophers have been arguing about the nature of time for thousands of years. National standards and state courses of study require that very young children be able to measure elapsed time to the hour and minute, but are they truly able to do so? This study focuses on children’s ability to quantify time at the very lowest level of quantification. Second, fourth, sixth, and eighth graders are interviewed using two tasks to determine whether they are able to separate their own actions from the actions of the timing device and to judge …

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Genaweave: A Generic Aspect Weaver Framework Based On Model -Driven Program Transformation, Suman Roychoudhury Jan 2008

Genaweave: A Generic Aspect Weaver Framework Based On Model -Driven Program Transformation, Suman Roychoudhury

All ETDs from UAB

Legacy software affects critical functions of our daily lives (e.g., general commercial transactions, scientific applications and military defense systems), and represents a significant investment by government, scientific and corporate institutions. As a consequence of the longevity of such systems, existing legacy software is subject to decay over a period of time, making it increasingly difficult to address changing stakeholder requirements. Modern research approaches for software engineering and programming language design, such as aspect-oriented software development (AOSD), have been investigated as effective techniques for improving modularization of software. However, a general trend in research for supporting aspects has focused primarily on …

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Investigation Of Lipoteichoic Acid Structure And Function To Establish Its Role In Gram-Positive Bacterial Infections, Ho Seong Seo Jan 2008

Investigation Of Lipoteichoic Acid Structure And Function To Establish Its Role In Gram-Positive Bacterial Infections, Ho Seong Seo

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Lipoteichoic acid (LTA) is an essential bacterial membrane polysaccharide (cell wall component) that is linked to a glycerol backbone with two acyl chains. Since an antibody to LTA has been shown to protect from Gr+ bacterial infections or colonization, and the mutant Gr+ bacteria which produce less amount of LTA have less pathogenic than WT, LTA may be an important role in Gr+ bacterial infection and inflammation. The currently accepted structure of pneumococcal LTA has the pentameric repeating unit bound to the lipid anchor {Glc(β1��3)AATGal(β1��3)Glc(α1��3)-acyl2Gro}. Unlike the lipid anchor of other Gr+ bacterial LTA, this pneumococcal LTA lipid anchor has …

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An Exploration Of Factors Related To Hypertension Control In African American And Caucasian Municipal Employees, Sunun Sinsuesatkul Jan 2008

An Exploration Of Factors Related To Hypertension Control In African American And Caucasian Municipal Employees, Sunun Sinsuesatkul

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Hypertension is a major contributor to morbidity, mortality, and medical costs in the United States. African Americans (AAs) have the highest prevalence of hypertension in the world, exhibiting at least twice the rate for Caucasians in almost every age and sex group. AAs are also at higher risk for complications from hypertension than Caucasians. While several factors have been proposed as accounting for those differences, there is no consensus on which factors may be responsible; the reasons for disparities in hypertension control in AAs are complex, and need further investigation. This study explored relationships between multiple factors to identify how …

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A Professional Journey: A Grounded Theory Study On The Experiences Of Reading Coaches As They Transition From Being A Teacher Of Children To A Leader Of Adults, Victoria Spear Jan 2008

A Professional Journey: A Grounded Theory Study On The Experiences Of Reading Coaches As They Transition From Being A Teacher Of Children To A Leader Of Adults, Victoria Spear

All ETDs from UAB

This qualitative grounded theory study described the experiences of Alabama Reading Initiative reading coaches as they transitioned from being teachers of children to being leaders of adults. This study addressed the gap in literature regarding the actual lived experiences of these professionals who were catalysts for change in the highly institutionalized culture of the public school setting. The study highlighted the triumphs and challenges inherent in the complex nature of institutional, professional, and personal change. The research participants were 23 practicing reading coaches in North Alabama and North Central Alabama. Forms of data collected included open-ended interviews, observations, and field …

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Changes In Short-Term Facilitation Are Opposite At Schaffer Collateral And Temporoammonic Ca1 Synapses In The Developing Rat Hippocampus, Haley E. Speed Jan 2008

Changes In Short-Term Facilitation Are Opposite At Schaffer Collateral And Temporoammonic Ca1 Synapses In The Developing Rat Hippocampus, Haley E. Speed

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Hippocampal CA1 pyramidal neurons integrate and filter spatial, temporal, and sensory information from the entorhinal cortex (EC) for memory storage. Synaptic transmission mediates the processing of incoming information, and recent studies have demonstrated that long-term changes in synaptic strength at CA1 synapses are important for learning and memory. Short-term changes in synaptic strength, occurring on a timescale of milliseconds to minutes, do not require lasting modifications and are rapidly reversible. Termed short-term plasticity, it is known to be important for dynamic gain control of synaptic transmission and neural computation. During late postnatal development, there are extensive developmental changes in rat …

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Analysis Of The Hedgehog Pathway In Pancreatic Adenocarcinoma, Adam Steg Jan 2008

Analysis Of The Hedgehog Pathway In Pancreatic Adenocarcinoma, Adam Steg

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Pancreatic adenocarcinoma (PAC) is the fourth leading cause of cancer mortality in the United States. Despite the use of highly aggressive treatment regimens (surgery, chemotherapy and radiation), almost all patients succumb to metastatic disease within 6-10 months of diagnosis. The hedgehog (HH) signaling pathway was originally discov-ered to play a critical role in mammalian embryological development. Interestingly, re-cent studies have suggested that aberrant expression of this pathway is involved in the initiation and continued growth of PAC. Small molecules that antagonize the transmem-brane protein Smoothened (Smo), a critical signaling component of the HH pathway, have proven effective in decreasing PAC …

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Randomized Controlled Trial Of Low Cost Interventions To Reduce Childhood Immunization Dropouts In Pakistan, Hussain Raza Usman Jan 2008

Randomized Controlled Trial Of Low Cost Interventions To Reduce Childhood Immunization Dropouts In Pakistan, Hussain Raza Usman

All ETDs from UAB

Childhood immunization coverage in Pakistan remains sub-optimal despite universal and free of cost availability of vaccines. Structural impediments to progress may include the immunization card that is hard to read and interpret. A randomized controlled trial was conducted to assess the effect of redesigned immunization card and center-based education to mothers on immunization completion at rural immunization centers in Karachi, Pakistan. Other objectives were to identify the predictors of immunization completion and to identify factors associated with delay at first dose of diphtheria-tetanuspertussis (DTP1). Mother-child units were enrolled from six immunization centers at DTP1 and randomized to four study groups: …

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