Digital Commons Network^™

Evaluation Of Imci Indicators Of Acute Bacterial Meningitis In Central Teaching Hospital For Child, Mayada Mohamed Ali Alansari

Iraqi Postgraduate Medical Journal

ABSTRACT: BACKGROUND: Acute bacterial meningitis [ABM] remains an important cause of death and neurological sequel in children, the clinical feature of meningitis is often nonspecific may overlap with those of other infection. Early diagnosis and appropriate treatment are perhaps the most important steps in management, but published data suggested that fewer than half of the cases of meningitis are identified at first assessment [1,2] . OBJECTIVE: Was to evaluate the clinical indicators of ABM of IMCI [integrated management of childhood illness] referral criteria of meningitis include [lethargy, unconsciousness, in ability to feed, neck stiffness, seizures] and other symptoms and sign. …

Is Enucleation Sufficient Treatment For Solitary Insulinoma?, Raafat Raof Ahmed

Iraqi Postgraduate Medical Journal

ABSTRACT: Enucleation is the traditional surgical procedure for removal of sporadic insulinoma, but this may associated with recurrence. This is a case report of thirty-five years old woman, who underwent enucleation for solitary insulinoma at the head of pancreases three years ago. Recently, she was complaining from recurrent attacks of hunger pain, dizziness, sweating, convulsion, behavioral changes and loss of consciousness. Endoluminal ultrasound revealed that there are bilobed mass or probably two masses related to the head/neck region of the pancreas about 1.5 cm in diameter. So the diagnosis of recurrent insulinoma was made and she was treated by complete …

Synthesis Analysis Of Regression Models With A Continuous Outcome, Andrew Zhou, Nan Hu, Guizhou Hu, Martin Root

UW Biostatistics Working Paper Series

Synthesis Analysis of Regression Models with a Continuous Outcome Xiao-Hua Zhou 1,2, Nan Hu 2, Guizhou Hu3, and Martin Root3 1 HSR&D Center of Excellence, VA Puget Sound Health Care System, Seattle, WA 98101. 2 Department of Biostatistics, University of Washington, Seattle, WA 98195. 3 BioSignia, Inc., 1822 East NC Highway 54, Suite 350, Durham, NC 27713 To estimate the multivariate regression model from multiple individual studies, it would be challenging to obtain results if the input from individual studies only provide univariate or incomplete multivariate regression information. Samsa et al [1] proposed a simple method to combine coefficients from …

Final Report: Task 22 — Extreme Ground Motion Studies, John G. Anderson, James N. Brune, Jaak J.K. Daemen, Matthew Purvance

Publications (YM)

TASK 22 consisted of two separate investigations into extreme ground motions due to seismic events, Subtask 1 and Subtask 2. Subtask 1 included field studies of geological formations that should put an upper bound on extreme ground motions that have happened at the site of the formations. The locations are critically selected to provide the most effective constraints possible on the validity of the probabilistic seismic hazard analysis for Yucca Mountain. Subtask 2 surveyed recorded ground motions from around the world, with the aim to draw general conclusions from these as to the conditions where extreme ground motions are observed. …

Gmac Step Draws U.S. In Deeper, Jon Hilsenrath, Aparajita Saha-Bubna

Documents

No abstract provided.

An Ion Selectivity Filter In The Extracellular Domain Of Cys-Loop Receptors Reveals Determinants For Ion Conductance, Scott Hansen, Hai Long Wang, Palmer Taylor, Steven M. Sine

ETSU Faculty Works

Neurotransmitter binding to Cys-loop receptors promotes a prodigious transmembrane flux of several million ions/s, but to date, structural determinants of ion flux have been identified flanking the membrane-spanning region. Using x-ray crystallography, sequence analysis, and single-channel recording, we identified a novel determinant of ion conductance near the point of entry of permeant ions. Co-crystallization of acetylcholine-binding protein with sulfate anions revealed coordination of SO42- with a ring of lysines at a position equivalent to 24 Å above the lipid membrane in homologous Cys-loop receptors. Analysis of multiple sequence alignments revealed that residues equivalent to the ring of lysines are negatively …

Structure And Dynamics Of Metalloproteins In Live Cells, Jeremy D. Cook, James E. Penner-Hahn, Timothy L. Stemmler

Biochemistry and Molecular Biology Faculty Publications

X-ray absorption spectroscopy (XAS) has emerged as one of the premier tools for investigating the structure and dynamic properties of metals in cells and in metal containing biomolecules. Utilizing the high flux and broad energy range of X-rays supplied by synchrotron light sources, one can selectively excite core electronic transitions in each metal. Spectroscopic signals from these electronic transitions can be used to dissect the chemical architecture of metals in cells, in cellular components and in biomolecules at varying degrees of structural resolution. With the development of ever-brighter X-ray sources, X-ray methods have grown into applications that can be utilized …

Cyber Civil Rights, Danielle Keats Citron

Faculty Scholarship

Social networking sites and blogs have increasingly become breeding grounds for anonymous online groups that attack women, people of color, and members of other traditionally disadvantaged groups. These destructive groups target individuals with defamation, threats of violence, and technology-based attacks that silence victims and concomitantly destroy their privacy. Victims go offline or assume pseudonyms to prevent future attacks, impoverishing online dialogue and depriving victims of the social and economic opportunities associated with a vibrant online presence. Attackers manipulate search engines to reproduce their lies and threats for employers and clients to see, creating digital “scarlet letters” that ruin reputations. Today’s …

Design, Synthesis, And Structure - Activity Relationship, Molecular Modeling, And Nmr Studies Of A Series Of Phenyl Alkyl Ketones As Highly Potent And Selective Phosphodiesterase-4 Inhibitors, Shilong Zheng, Gurpreet Kaur, Huanchen Wang, Minyong Li, Megan Macnaughtan, Xiaochuan Yang, Suazette Reid, James Prestegard, Binghe Wang, Hengming Ke

Faculty Publications

Phosphodiesterase 4 catalyzes the hydrolysis of cyclic AMP and is a target for the development of anti-inflammatory agents. We have designed and synthesized a series of phenyl alkyl ketones as PDE4 inhibitors. Among them, 13 compounds were identified as having submicromolar IC50 values. The most potent compounds have IC50 values of in the mid- to low-nanomolar range. Compound 5v also showed preference for PDE4 with selectivity of >2000-fold over PDE7, PDE9, PDE2, and PDE5. Docking of 5v, 5zf, and 5za into the binding pocket of the PDE4 catalytic domain revealed a similar binding profile to PDE4 with rolipram except that …

Model Spesifikasi Dinamis Permintaan Rokok: Rasionalkah Perokok Indonesia?, Budi Hidayat, Hasbullah Thabrany

Kesmas

Studi ini mengestimasi model spesifikasi dinamis permintaan (demand) rokok di Indonesia. Tujuannya adalah untuk menguji hipotesis kecanduan rasional perokok, dan menghitung elastisitas harga rokok jangka pendek dan jangka panjang. Analisis diaplikasikan pada data agregat individu yang dibentuk dari tiga tahapan survei panel IFLS selama tahun 1993-2000. Studi ini menjajagi sejumlah teknik ekonometrik dan memilih teknik tercocok atas dasar serangkaian uji statistik. Hasilnya menunjukkan bahwa rokok terbukti sebagai produk yang menimbulkan kecanduan (koefisien konsumsi masa lampau positif dan signifikan pada 1%). Sedangkan koefisien negatif dan signifikan untuk konsumsi rokok masa depan menunjukan sifat kecanduan miopik, artinya para perokok bersifat tidak rasional. …

Studi Kualitatif : Pelayanan Rujukan Asfiksia Bayi Baru Lahir Di Kabupaten Cirebon Jawa Barat, Ella Nurlaella Hadi

Kesmas

Pada tahun 2005, studi penatalaksanaan asfiksia bayi baru lahir (BBL) oleh bidan di desa Kabupaten Cirebon menemukan kematian asfiksia BBL yang dirujuk ke rumah sakit masih tinggi. Penelitian ini bertujuan untuk mendapatkan informasi yang mendalam tentang proses rujukan, alur penanganan rujukan kasus asfiksia BBL di RS dan kualitas pelayanan di RS rujukan Kabupaten Cirebon. Untuk itu, digunakan pendekatan kualitatif dengan metode studi kasus. Hasil penelitian menunjukkan BdD sudah menangani asfiksia BBL dengan benar, tetapi rujukan sering terlambat karena adanya faktor penghambat dari keluarga (ekonomi dan keputusan merujuk harus melibatkan keluarga besar) dan faktor lingkungan (transportasi di desa terpencil sulit terutama …

Faktor Sosio Ekonomi Yang Mempengaruhi Kepatuhan Minum Obat Antihipertensi, Pujiyanto Pujiyanto

Kesmas

Hipertensi merupakan penyakit degeneratif yang banyak diderita penduduk dengan kecenderungan meningkat seiring bertambahnya umur. Dengan bertambahnya umur harapan hidup maka dimasa depan hipertensi akan menjadi masalah kesehatan yang serius. Salah satu upaya mengatasi hipertensi adalah dengan minum obat antihipertensi. Keteraturan meminum obat ditentukan oleh kepatuhan. Penelitian ini bertujuan untuk mengelaborasi pengaruh faktor sosio-ekonomi terhadap kepatuhan minum obat. Jenis penelitian adalah studi kualitatif dengan teknik wawancara mendalam. Informan adalah penderita hipertensi yang tinggal di wilayah kerja Puskesmas Beji Kota Depok, berjumlah 8 orang meliputi kategori lansia/non lansia dan laki-laki/perempuan. Wawancara dilakukan di rumah informan pada minggu pertama dan kedua Juni 2007. …

December 24th 2008, Hispanic News

Inland Empire Hispanic News

No abstract provided.

Is The Pamela Positron Excess Winos?, Scott Watson, Phill Grajek, Gordon L. Kane, Daniel J. Phalen, Aaron Pierce

Physics - All Scholarship

Recently the PAMELA satellite-based experiment reported an excess of galactic positrons that could be a signal of annihilating dark matter. The PAMELA data may admit an interpretation as a signal from a wino-like LSP of mass about 200 GeV, normalized to the local relic density, and annihilating mainly into W-bosons. This possibility requires the current conventional estimate for the energy loss rate of positrons be too large by roughly a factor of five. Data from anti-protons and gamma rays also provide tension with this interpretation, but there are significant astrophysical uncertainties associated with their propagation. It is not unreasonable to …

Um Releases New Theory Of Bird Evolution, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.

Energy-Efficient Peer-To-Peer Caching And Mobility Management In 4g Hybrid Networks, Mehdi Azami, Bharat Bhargava

Department of Computer Science Technical Reports

No abstract provided.

Genotyping And Drug Resistance Patterns Of M. Tuberculosis Strains In Pakistan., Mahnaz Tanveer, Zahra Hasan, Amna R Siddiqui, Asho Ali, Akbar Kanji, Solomon Ghebremicheal, Rumina Hasan

Department of Pathology and Laboratory Medicine

Background:The incidence of tuberculosis in Pakistan is 181/100,000 population. However, information about transmission and geographical prevalence of Mycobacterium tuberculosis strains and their evolutionary genetics as well as drug resistance remains limited. Our objective was to determine the clonal composition, evolutionary genetics and drug resistance of M. tuberculosis isolates from different regions of the country.

Methods:

M. tuberculosis strains isolated (2003-2005) from specimens submitted to the laboratory through collection units nationwide were included. Drug susceptibility was performed and strains were spoligotyped.

Results:

Of 926 M. tuberculosis strains studied, 721(78%) were grouped into 59 "shared types", while 205 (22%) were identified …

Splenic Rupture, Secondary To G-Csf Use For Chemotherapy Induced Neutropenia: A Case Report And Review Of Literature., Nehal Masood, Asim Jamal Shaikh, Wasim Ahmed Memon, Romana Idress

Section of Haematology/Oncology

Introduction: Chemotherapy Induced neutropenia is a frequent and serious complication of cytotoxic cancer treatment. Granulocyte colony stimulating factors (G-CSF) are frequently used to counter neutropenia, attempt rapid recovery of Patients and allow for continuation of treatment without compromise on dose, especially in curative malignancies. Generally regarded as safe, G-CSF use has been very rarely reported to have resulted in serious side effects, such as, splenic rupture. Case Presentation: We are reporting a case of a twenty years old man, who was being treated for T cell acute lymphoblastic leukemia and received colony stimulating factors for treatment of severe neutropenia and …

Comment Letters On Proposed Statement On Auditing Standards: Compliance Audits, December 24, 2008, American Institute Of Certified Public Accountants. Auditing Standards Board

Exposure Drafts, Comment Letters, and Statements of Position

No abstract provided.

Lipid Raft Mediated Lyn Kinase Activation Regulates Host Innate Immune Response Against Pseudomonas Aeruginosa Lung Infection, Shibichakravarthy Kannan

Theses and Dissertations

Pseudomonas aeruginosa (PA) is a common opportunistic pathogen that invades the susceptible host. Alveolar macrophages (AM) play a pivotal role in defending against invading pathogens in the lungs. The effectiveness of AM in combating PA infection has not been studied in detail. The goal was to identify the key components involved in mounting an effective innate immune response using the murine lung infection as a model to understand the host - pathogen interactions. Our most important finding was the involvement of Lyn tyrosine kinase, a member of Src family tyrosine kinases, in orchestrating the host cell response to PA invasion. …

Applying Marine Protected Area Design Models In Large Estuarine Systems, Roman Zajac, Amanda E. Neely

Biology and Environmental Science Faculty Publications

Several types of design models are currently being used to develop marine protected areas (MPAs) for conservation of coastal and pelagic ecosystems. However, few studies have applied these models in large estuaries which have unique characteristics that need to be considered in MPA design, including strong physical, chemical and biological gradients and significant human impacts. We explored how one design model, MARXAN, can be applied to estuarine systems by developing MPA design scenarios for Long Island Sound, an estuary in the northeastern USA. Using sedimentary texture as a proxy for habitats, we modeled and tested several scenarios where conservation goals …

Photosynthetic Response Of Soybean To Twospotted Spider Mite (Acari: Tetranychydae) Injury, Adeney De Freitas Bueno, Regiane Cristina Oliveira De Freitas Bueno, Paul David Nabity, Leon George Higley, Odair Aparecido Fernandes

School of Natural Resources: Faculty Publications

The twospotted spider mite Tetranychus urticae Koch is a common pest on soybean plants. To clarify plantarthropod interaction on mite-soybean system, leaf fluorescence, photosynthetic responses to variable carbon dioxide levels, and chlorophyll content were evaluated. Significant photosynthetic rate reduction was observed due to stomatal limitation. Stomatal closure was the major plant physiological response. As a consequence, there was reduction in photosynthetic rates. Surprisingly, plants did not show chlorophyll content reduction associated with photosynthetic impairment. No differences in fluorescence data indicate that T. urticae injury did not impair the function of light harvesting and photoelectron transport. These results showed that T. …

Platelet-Derived Growth Factor Selectively Inhibits Nr2b-Containing N-Methyl-D-Aspartate Receptors In Ca1 Hippocampal Neurons, Michael A. Beazely, Aeni Lim, Hongbin Li, Catherine Trepanier, Xuanmao Chen, Bikram Sidhu, John F. Macdonald

Molecular, Cellular & Biomedical Sciences

Platelet-derived growth factor (PDGF) β receptor activation inhibits N-methyl-D-aspartate (NMDA)-evoked currents in hippocampal and cortical neurons via the activation of phospholipase Cγ, PKC, the release of intracellular calcium, and a rearrangement of the actin cytoskeleton. In the hippocampus, the majority of NMDA receptors are heteromeric; most are composed of 2 NR1 subunits and 2 NR2A or 2 NR2B subunits. Using NR2B- and NR2A-specific antagonists, we demonstrate that PDGF-BB treatment preferentially inhibits NR2B-containing NMDA receptor currents in CA1 hippocampal neurons and enhances long-term depression in an NR2B subunit-dependent manner. Furthermore, treatment of hippocampal slices or cultures with PDGF-BB decreases the surface …

Virtual Environments Innovation And R&D Activities: Management Challenges, N. Ale Ebrahim, S. Ahmed, Z. Taha

Research Publications (2006 to 2010)

Companies will not survive long unless they join a threefold revolution in management itself, innovation, and information technology. Innovation plays a central role in economic development, at regional and national level. In the competitive environment companies are obliged to produce more rapidly, more effectively and more efficiently in new product development which is a result of research and development (R&D) activities. It is necessary for them to put together different capabilities and services with the goal, through cooperation between suppliers and customers, service providers and scientific institutions to achieve innovations of high quality. Depending on the type of industry, the …

Maskless Photolithography For Using Photoreactive Agents, David P. Fries

USF Patents

The present invention relates to maskless photolithography using a patterned light generator for creating 2-D and 3-D patterns on objects using photoreactive chemicals. In an embodiment, the patterned light generator uses a micromirror array to direct pattern light on a target object. In an alternate embodiment, the patterned light generator uses a plasma display device to generate and direct patterned light onto a target object. Specifically, the invention provides a maskless photolithography system and method for creating molecular imprinted array devices, integrated microsensors and fluidic networks on a substrate, integrated circuits of conducting polymers, and patterns on substrates using photochemical …

State Aid: Commission Approves Italian Recapitalisation Scheme For Financial Institutions, European Union: European Commission

Documents

No abstract provided.

State Aid: Commission Approves Modifications To Uk Financial Support Measures To The Banking Industry, European Union: European Commission

Documents

No abstract provided.

State Aid: Commission Approves Spanish Guarantee Scheme For Credit Institutions, European Union: European Commission

Documents

No abstract provided.

State Aid: Commission Approves Italian Recapitalisation Scheme For Financial Institutions, European Commission

Documents

No abstract provided.

Constructing Diabatic States From Adiabatic States: Extending Generalized Mulliken–Hush To Multiple Charge Centers With Boys Localization, Joseph E. Subotnik, Robert J. Cave, Sina Yeganeh, Mark A. Ratner

All HMC Faculty Publications and Research

This article shows that, although Boys localization is usually applied to single-electron orbitals, the Boys method itself can be applied to many electron molecular states. For the two-state charge-transfer problem, we show analytically that Boys localization yields the same charge-localized diabatic states as those found by generalized Mulliken–Hush theory. We suggest that for future work in electron transfer, where systems have more than two charge centers, one may benefit by using a variant of Boys localization to construct diabatic potential energy surfaces and extract electronic coupling matrix elements. We discuss two chemical examples of Boys localization and propose a generalization …