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Synthesis And Characterization Of Polymer Brushes For Controlled Adsorption Of Proteins, Olha Hoy

All Dissertations

Performance of biomedical devices to a large extent depends on the interactions between the device surface and the biological liquids/protein molecules. To achieve controllable interactions between the device and biomolecules and still retain the required mechanical strength on the whole, modification of the surface is often done.
In the present study surface properties were modified through a polymer brush approach. After the modification, surfaces gain tunability toward protein adsorption. Mixed polymer brushes consisting of protein repelling and protein attractive components were used, with a 'grafting to' method employed for the synthesis of polymer layers. First, poly(ethylene glycol), the protein repelling …

Fall Commencement [Program], December 20, 2008, University Of Northern Iowa

UNI Commencement Programs

The program of the commencement ceremonies, including a list of institutional leadership, a list of the departments by college, awards given at the ceremonies, and a list of undergraduate and graduate degree candidates.

2008 Fall Commencement, Harding University

Commencement Programs

Program for the Commencement on December 20.

Commencement Speaker: Mike Justus

Holy Cross Magazine, Vol. 43, No. 1, Winter 2009, College Of The Holy Cross

Holy Cross Magazine

Defining “The Cooz”
A personal essay
By Dave Anderson ’51

Ever Striving for “the Greater”
College president emeritus, Rev. John E. Brooks, S.J., ’49, reflects on the character of his longtime friend
By Clark Booth ’61

One on one with Bob Cousy
On Oct. 27, Bob Cousy ’50 sat down with sports journalist Clark V. Booth ’61 to discuss Bob’s extraordinary life and career and to reflect upon his legacy in the world of basketball— and beyond.
By Clark Booth ’61

Syllabus: Magic Lessons
Jonathan Mulrooney, professor of English
By Pam Reponen

1962-63: Big Men on Campus
The Cross and …

159th Commencement, Winter

Commencement Programs

No abstract provided.

Ck2 Contributes To The Synergistic Effects Of Bmp7 And Bdnf On Smad 1/5/8 Phosphorylation In Septal Neurons, Florence Chaverneff

Open Access Dissertations

The combination of bone morphogenetic protein 7 (BMP7) and neurotrophins (e.g. brain-derived neurotrophic factor, BDNF) protects septal neurons during hypoglycemic stress. I investigated the signaling mechanisms underlying this synergistic protection. BMP7 (5 nM) increased phosphorylation and nuclear translocation of BMP-responsive Smads 1/5/8 within 30 min in cultures of rat embryonic septal neurons. BDNF (100 ng/ml) enhanced the BMP7-induced increase in phospho-Smad levels in both nucleus and cytoplasm; this effect was more pronounced after a hypoglycemic stress. BDNF increased both Akt and Erk phosphorylation, but pharmacological blockade of these kinase pathways (with wortmannin and U0126, respectively) did not reduce the Smad …

2008 Winter Boise State University Commencement Program

Commencement Programs

No abstract provided.

Aboriginal Interpretation In Australian Wildlife Tourism, Heather Zeppel, Sue Muloin

Aboriginal Policy Research Consortium International (APRCi)

This paper evaluates Aboriginal cultural interpretation at wildlife attractions and on wildlife tours in Australia. The sites included 14 wildlife parks or zoos; three Aboriginal owned emu or crocodile farms; and 16 wildlife tours, river cruises or resorts with Indigenous interpretation of wildlife. Telephone interviews were conducted with 35 manage (nine Indigenous) and 26 Indigenous staff at wildlife attractions that included verbal or written Aboriginal wildlife interpretation. The Indigenous guides verbally presented both traditional uses and personal stories about Australian wildlife followed by Aboriginal 'Dreaming' or creation stories about totemic animal species. Non-Indigenous staff explained traditional Aboriginal uses of wildlife …

A Centennial Celebration, December Commencement 2008, University Of Nebraska At Omaha

Commencement Programs

No abstract provided.

Ngasp - The Nematode Genome Annotation Assessment Project, Avril Coghlan, Tristan J. Fiedler, Sheldon J. Mckay, Paul R. Flicek, Todd W. Harris, Darin Blasiar, Lincoln D. Stein

Biomedical Engineering and Sciences Faculty Publications

While the C. elegans genome is extensively annotated, relatively little information is available for other Caenorhabditis species. The nematode genome annotation assessment project (nGASP) was launched to objectively assess the accuracy of protein-coding gene prediction software in C. elegans, and to apply this knowledge to the annotation of the genomes of four additional Caenorhabditis species and other nematodes. Seventeen groups worldwide participated in nGASP, and submitted 47 prediction sets across 10 Mb of the C. elegans genome. Predictions were compared to reference gene sets consisting of confirmed or manually curated gene models from WormBase. Results: The most accurate gene-finders were …

Winter Commencement: December 19, 2008, University Of North Dakota

UND Commencement Programs

UND Winter Commencement program from December 19, 2008.

Reducing The Public Health Impact Of Bovine Tuberculosis By Controlling Disease Transmission Between Cattle And White-Tailed Deer In Northwestern Minnesota, Barbara Knust

Michigan Bovine Tuberculosis Bibliography and Database

Bovine tuberculosis, caused by infection with Mycobacterium bovis, is a re-emerging zoonotic disease. It has staged a comeback by establishing infections in wildlife and cattle, creating the potential for human disease in locations where it was thought to be under control. In northwestern Minnesota, infected cattle and white-tailed deer were first discovered in 2005. A major bovine tuberculosis eradication campaign is underway in the state, with multiple efforts employed to control M. bovis infection in both cattle and deer populations. In order to effectively eradicate bovine tuberculosis in Minnesota, there is a need for better understanding of the …

Methylation-Sensitive Linking Libraries Enhance Gene-Enriched Sequencing Of Complex Genomes And Map Dna Methylation Domains, William Nelson, Meizhong Luo, Jianxin Ma, Matt Estep, James Estill, Ruifeng He, Jayson Talag, Nicholas Sisneros, David Kudrna, Hyeran Kim, Jetty Ss Ammiraju, Kristi Collura, Arvind K. Bharti, Joachim Messing, Rod A. Wing, Phillip Sanmiguel, Jeffrey L. Bennetzen, Carol Soderlund

Department of Horticulture & Landscape Architecture Faculty Publications

Background

Many plant genomes are resistant to whole-genome assembly due to an abundance of repetitive sequence, leading to the development of gene-rich sequencing techniques. Two such techniques are hypomethylated partial restriction (HMPR) and methylation spanning linker libraries (MSLL). These libraries differ from other gene-rich datasets in having larger insert sizes, and the MSLL clones are designed to provide reads localized to "epigenetic boundaries" where methylation begins or ends.

Results

A large-scale study in maize generated 40,299 HMPR sequences and 80,723 MSLL sequences, including MSLL clones exceeding 100 kb. The paired end reads of MSLL and HMPR clones were shown to …

Glucose And Glucosamine Derivatives As Novel Low Molecular Weight Gelators, Sherwin Cheuk

LSU New Orleans Theses and Dissertations

Low molecular weight gelators (LMWGs) are small molecules that are capable of entrapping solvents to form a gel in organic solvents or aqueous solution. These compounds rely solely on noncovalent forces to form the fibrous networks necessary to entrap a variety of solvents. The organogels and hydrogels thus formed could have applications in a variety of fields from environmental to biological to medicinal. Carbohydrates are ideal starting materials to synthesize LMWGs, because of their natural abundance, dense chirality, and biocompatibility. D-Glucose is the most common monosaccharide and D-glucosamine is isolated from natural sources, such as crab shells. Several series of …

Response Of Barrier Island Fish Assemblages To Impacts From Multiple Hurricanes: Assessing Resilience Of Chandeleur Island Fish Assemblages To Hurricanes Ivan (2004) And Katrina (2005), Mark Chad Ellinwood

LSU New Orleans Theses and Dissertations

Hurricanes can temporarily disrupt seasonal patterns of fish assemblage change or result in permanent changes in fish assemblages. I studied the effects of two hurricanes on fish assemblages at the Chandeleur Islands and the possible influence that storm-generated tidal channels may have on the composition of local fish assemblages. I also compared recently collected data to historic ichthyofaunal survey data collected over thirty years ago at the Chandeleur Islands. Near shore fish assemblages changed the most after hurricanes but changes in species composition were primarily due to increases in abundance and diversity. During July 2007 there was no significant difference …

A Semi-Supervised Information Extraction Framework For Large Redundant Corpora, Eric Normand

LSU New Orleans Theses and Dissertations

The vast majority of text freely available on the Internet is not available in a form that computers can understand. There have been numerous approaches to automatically extract information from human- readable sources. The most successful attempts rely on vast training sets of data. Others have succeeded in extracting restricted subsets of the available information. These approaches have limited use and require domain knowledge to be coded into the application. The current thesis proposes a novel framework for Information Extraction. From large sets of documents, the system develops statistical models of the data the user wishes to query which generally …

Assessment Of Ambient Air Particulate Matter In The New Orleans Historic District , Federico Portillo

LSU New Orleans Theses and Dissertations

Particulate matter in the ambient air of down-town New Orleans, LA, is not currently recorded by any government, state, or private organization. This research quantified particulate matter (PM) and its metal concentration in ambient air of the New Orleans Historic District. Both, PM10 (PM less than 10 micron in size) and PM2.5 (PM less than 2.5 micron in size) were quantified by gravimetric analysis using an Andersen Dichotomous Sampler (Series 240). Posterior to gravimetric analysis, the filters were analyzed with a fluorescent test method using an Innov-X Portable XRF Analyzer (Model A-6500). This study demonstrated that the ambient air of …

Preparation, Characterization, And Application Of Liposomes In The Study Of Lipid Oxidation Targeting Hydroxyl Radicals, Chanel Fortier

LSU New Orleans Theses and Dissertations

In the onset of many chronic illnesses including Parkinson’s, Alzheimer’s, and cardiovascular diseases, there is evidence to support the delicate balance between prooxidant and antioxidant species is shifted in favor of the former. Under these conditions, many reactive oxygen species (ROS) including hydroxyl radicals, are generated. Hydroxyl radicals formed in close proximity to DNA, nucleotides, proteins, and lipids rapidly oxidize these biological molecules in a nonspecific way. However, their toxicity is limited by their short lifetimes. Currently, the mechanism by which hydroxyl radicals are involved in the onset of many illnesses, particularly with regard to lipid peroxidation, has yielded some …

Application Of X-Ray Diffraction Methods And Molecular Mechanics Simulations To Structure Determination And Cotton Fiber Analysis, Zakhia Moore

LSU New Orleans Theses and Dissertations

The results of three very different studies are presented. X-ray diffraction has been utilized for single-crystal structure determinations, fiber diffraction analyses, and in conjunction with molecular modeling of Cellulose IIII. Although each technique is different in its sampling, data acquisition, data treatment, and identification, the common denominator has been the use of x-rays. The single-crystal structure determination of ethylene glycol bis(tropane-3-carboxylate) is presented as an example of the use of modern single-crystal x-ray instrumentation including the use of coupled charged devices (CCDs) as detectors for accurate data collection and rapid elucidation of crystal structures. The structure determination of Cellulose IIII …

Responses Of A Louisiana Oligohaline Marsh Plant Community To Nutrient Loading And Disturbance, Danielle Meert

LSU New Orleans Theses and Dissertations

Aboveground plant community dynamics in the oligohaline marsh at Big Branch Marsh National Wildlife Refuge, Louisiana, USA, were assessed in response to nutrient loading (3 N x 3 P treatments) and disturbance (both planned lethal disturbance and stochastic tropical storm/hurricane disturbance). Sampling was conducted seasonally from April 2004 to September 2006. Spartina patens and Schoenoplectus americanus are co-dominant plant species in this marsh. Low N-loading additions resulted in increased S. patens cover. However, increased N loading did not result in a shift in plant community composition despite S. americanus consistently having higher leaf tissue N than S. patens. Our results …

Applications Of Mass Spectrometry To Analysis Of Prodiginines, Bioactivated Methylenedianiline Intermediates, And Hypoxia Induced Changes In The Zebrafish Skeletal Muscle Proteome, Kan Chen

LSU New Orleans Theses and Dissertations

Mass spectrometry coupled with liquid chromatography and gel electrophoresis enables separation and detection of components in a complex mixture. During the last two decades, its applications were dramatically extended and remarkable progress has been made in many fields, in particular, environmental and biological analyses. This dissertation focuses on identification and characterization of biologically active compounds and comparative analysis of protein expression changes. The first two projects (Chapters 2 and 3) focus on the application of LC/MS approach to profile the bioactivated intermediates of 4, 4'-methylenedianiline (DAPM) from rat vascular smooth muscle cells (VSMCs) and bile. In our study, several DAPM …

Synthesis And Spectroscopic Study Of Anticancer Agent A-007 Prodrugs And Progress Towards The Synthesis Of Tetramic Acid Antibiotics, Sarada Sagiraju

LSU New Orleans Theses and Dissertations

4, 4'-Dihydroxybenzophenone-2, 4-dinitrophenylhydrazone (A-007) has recently completed a phase-I clinical trial, and objective responses were seen in advanced breast cancer, lung cancer, ovarian cancer, melanoma, skin cancer and non-Hodgkin's lymphoma. Despite the promising results in the clinical trials, the major disadvantage to using A-007 as a broad-scale therapeutic is its poor water solubility. To make use of this promising anticancer drug either orally or intravenously, the short-term obstacle must be to overcome the limited solubility of A-007 in water. There are several approaches to overcome this obstacle. The first approach is to make hydrolysable prodrugs of A-007. The second approach …

Utilitizing And Moving Beyond A Constructionist Approach To Trace The Emergence Of Racial And Ethnic Identities Among Pre-Mexican, Mexican And Americans Of Mexican Descent, Owen Williamson

Theses and Dissertations

Cornell and Hartmann (2007) developed a constructionist framework that can describe the development of racial and ethnic identities. Yet this framework has greater utility than its authors have intended as it also provides the best rubric to date for comprehending the transitions between collective identity group types. This study engages in a thorough investigation of the development of racial and ethnic identities within the context of those that precede it via an ethnohistorical analysis. It also demonstrates that this framework is capable of describing pre-modern religious and national identity types in addition to racial and ethnic identity types. This permits …

Sex Expression In A Rainforest Understory Herb, Begonia Urophylla, John Cozza

Open Access Dissertations

Monoecy, the production of distinct male and female flowers on the same plant, is an important, though little studied, sexual strategy in the rainforest understory. This study of a monoecious plant discovered a cue to induce flowering, explored the interplay of gender constraint vs. plasticity in a natural population, and tested possible causes of gender in two laboratory experiments. An experiment in the lab found that reduced photoperiod for three weeks is an unambiguous cue for flowering. The remarkably long inductive period is followed by a long and variable period of floral initiation. This results in only partial synchronization of …

The Importance Of Sexual And Clonal Reproduction For Population Dynamics In The Understory Herb Calathea Marantifolia (Marantaceae), David P. Matlaga

Open Access Dissertations

I addressed how light availability influences sexual and clonal offspring production, demographic performance and contribution to population dynamics by studying the Neotropical understory herb Calathea marantifolia across a light gradient in Costa Rica. To understand how demographic performance was influenced by light availability I conducted a transplant experiment in the field. Both seedlings and clonal offspring grew best when planted in high light areas, but seedlings showed a faster and more dramatic response. Survival of seedlings was greatest in high light sites but clonal offspring survival was greatest where light availability was low. To examine the demographic consequences of physiological …

Council On Academic Affairs Minutes, Dec 18, 2008, Eastern Kentucky University

Council on Academic Affairs

No abstract provided.

Stakes Increase For End Of Course Exams In 2009-10, Sarah C. Mckenzie, Gary W. Ritter

Policy Briefs

As of the 2009-10 academic year, high school students in Arkansas will be required to pass so called “End of Course” (or “EOC”) examinations in Algebra I, Biology, Geometry, and English. Students who fail to meet the requisite passing standard will be required to retake the class or to pass “an appropriate alternative exit course in order to receive credit for the course on his or her transcript and in order to graduate.” In other words, these four EOC tests will become high school exit exams. Thus, as of 2009-10, Arkansas will join some 23 other states that have high …

The Minutes Of The Marshall University Staff Council Meeting, December 2008, Marshall University Staff Council

Staff Council Minutes

No abstract provided.

A Trust-Based Secure Service Discovery (Tssd) Model For Pervasive Computing, Sheikh Iqbal Ahamed, Moushumi Sharmin

Mathematics, Statistics and Computer Science Faculty Research and Publications

To cope with the challenges posed by device capacity and capability, and also the nature of ad hoc networks, a Service discovery model is needed that can resolve security and privacy issues with simple solutions. The use of complex algorithms and powerful fixed infrastructure is infeasible due to the volatile nature of pervasive environment and tiny pervasive devices. In this paper, we present a trust-based secure Service discovery model, TSSD (trust-based secure service discovery) for a truly pervasive environment. Our model is a hybrid one that allows both secure and non-secure discovery of services. This model allows Service discovery and …

Topical Application Of Entry Inhibitors As "Virustats" To Prevent Sexual Transmission Of Hiv Infection, Michael M. Lederman, Robin L.P. Jump, Heather A. Pilch-Cooper, Scott F. Sieg

Faculty Scholarship

With the continuing march of the AIDS epidemic and little hope for an effective vaccine in the near future, work to develop a topical strategy to prevent HIV infection is increasingly important. This stated, the track record of large scale "microbicide" trials has been disappointing with nonspecific inhibitors either failing to protect women from infection or even increasing HIV acquisition. Newer strategies that target directly the elements needed for viral entry into cells have shown promise in non-human primate models of HIV transmission and as these agents have not yet been broadly introduced in regions of highest HIV prevalence, they …