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2008

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The 3′ Processing Factor Cstf Functions In The Dna Repair Response, Nurit Mirkin, Danae Fonseca, Samia Mohammed, Murat A. Cevher, James L. Manley, Frida E. Kleiman Apr 2008

The 3′ Processing Factor Cstf Functions In The Dna Repair Response, Nurit Mirkin, Danae Fonseca, Samia Mohammed, Murat A. Cevher, James L. Manley, Frida E. Kleiman

Publications and Research

Following DNA damage, mRNA levels decrease, reflecting a coordinated interaction of the DNA repair, transcription and RNA processing machineries. In this study, we provide evidence that transcription and polyadenylation of mRNA precursors are both affected in vivo by UV treatment. We next show that the polyadenylation factor CstF, plays a direct role in the DNA damage response. Cells with reduced levels of CstF display decreased viability following UV treatment, reduced ability to ubiquitinate RNA polymerase II (RNAP II), and defects in repair of DNA damage. Furthermore, we show that CstF, RNAP II and BARD1 are all found at sites of …

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The Influence Of Ph On Nucleation, Solubility And Structure Of Lysozyme Protein Crystals, Marc C. Apgar Apr 2008

The Influence Of Ph On Nucleation, Solubility And Structure Of Lysozyme Protein Crystals, Marc C. Apgar

USF Tampa Graduate Theses and Dissertations

X-ray diffraction from protein crystals remains the most reliable way to determine the molecular structure of proteins, and how this structure relates to biological function. However, we still lack the ability to predict solution conditions that support the nucleation and growth of high-quality protein crystals for X-ray diffraction studies. The overall goal of this thesis is two-fold: (a) determine the nucleation behavior and solubilities for lysozyme crystals with two distinct crystal structures (orthorhombic vs. tetragonal) and (b) investigate whether these changes in crystal habit and crystal solubility correlate with any discontinuities in the liquid-liquid phase boundary of lysozyme that occurs …

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Download The Pdf Of The Full Issue Apr 2008

Download The Pdf Of The Full Issue

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.

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Mustang Daily, April 4, 2008 Apr 2008

Mustang Daily, April 4, 2008

Cal Poly Student Newspaper

Student newspaper of California Polytechnic State University, San Luis Obispo, CA.

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2008 Undergraduate Research Symposium Abstract Book, Academic Center For Enrichment Apr 2008

2008 Undergraduate Research Symposium Abstract Book, Academic Center For Enrichment

Undergraduate Research Symposium Abstract Books

Abstract book from the 2008 UMM Undergraduate Research Symposium (URS) which celebrates student scholarly achievement and creative activities.

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A Bayesian Approach To Modeling Associations Between Pulsatile Hormones, Nichole E. Carlson, Timothy D. Johnson, Morton B. Brown Apr 2008

A Bayesian Approach To Modeling Associations Between Pulsatile Hormones, Nichole E. Carlson, Timothy D. Johnson, Morton B. Brown

The University of Michigan Department of Biostatistics Working Paper Series

Many hormones are secreted in pulses. The pulsatile relationship between hormones regulates many biological processes. To understand endocrine system regulation, time series of hormone concentrations are collected. The goal is to characterize pulsatile patterns and associations between hormones. Currently each hormone on each subject is fitted univariately. This leads to estimates of the number of pulses and estimates of the amount of hormone secreted; however, when the signal-to-noise ratio is small, pulse detection and parameter estimation remains di±cult with existing approaches. In this paper, we present a bivariate deconvolution model of pulsatile hormone data focusing on incorporating pulsatile associations. Through …

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Inter-Institutional Faculty Senate April 2008, Portland State University Faculty Senate Apr 2008

Inter-Institutional Faculty Senate April 2008, Portland State University Faculty Senate

Faculty Senate Monthly Packets

Inter-institutional Faculty Senate minutes from meeting held April 4, 2008. This item contains the agenda, minutes, and attachments for the Faculty Senate meeting on this date. Some issues accompanied by reports from officers of administration and faculty committees.

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Modeling Runoff And Sediment Yield From A Terraced Watershed Using Wepp, Mary Carla Mccullough, Dean E. Eisenhauer, Mike Dosskey Apr 2008

Modeling Runoff And Sediment Yield From A Terraced Watershed Using Wepp, Mary Carla Mccullough, Dean E. Eisenhauer, Mike Dosskey

United States Department of Agriculture, Forest Service / University of Nebraska-Lincoln: Faculty Publications

The watershed version of WEPP (Water Erosion Prediction Project) was used to estimate 50-year runoff and sediment yields for a 291 ha watershed in eastern Nebraska that is 90% terraced and which has no historical gage data. The watershed has a complex matrix of elements, including terraced and non-terraced subwatersheds, multiple combinations of soils and land management, a grassed-waterway network, and natural stream channels leading to the outlet. The objectives of this study were to model the study watershed using WEPP and to evaluate model results compared to literature values. WEPP estimated the sediment yield to be 1.9 T/ha/yr, the …

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Campus Report, Vol. 35, No. 8, University Of Dayton Apr 2008

Campus Report, Vol. 35, No. 8, University Of Dayton

Campus Report

Making history at RISE; space shuttle research; consoling grief at Northern Illinois University; and carrying the Marianist charism.

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The Tiger Vol. 102 Issue 10 2008-04-04, Clemson University Apr 2008

The Tiger Vol. 102 Issue 10 2008-04-04, Clemson University

Tiger Newspapers

No abstract provided.

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Flyer News, Vol. 55, No. 36 (April 4, 2008), University Of Dayton Apr 2008

Flyer News, Vol. 55, No. 36 (April 4, 2008), University Of Dayton

Flyer News

Student-run newspaper of the University of Dayton

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The Wooster Voice (Wooster, Oh), 2008-04-04, Wooster Voice Editors Apr 2008

The Wooster Voice (Wooster, Oh), 2008-04-04, Wooster Voice Editors

The Voice: 2001-2011

This edition of the Wooster Voice was published April 4 of 2008 and it is eight pages long. Contracting companies have been surveying Beall Ave to propose bids to the college for the 'beautification'. The College of Wooster Art Museum is featuring the works of studio art faculty and the museum preparator Doug McGlumphy. Hunger and Homelessness week is sponsored by Peace by Peace from March 31 to April 5. The South Asia Committee is hosting South Asia Week which started on April 1. An exhibit titled "The Anne Frank Story" is featured on the art wall in Lowry. Athletic …

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2008 Little International Agricultural Exposition Catalog, Little International Agricultural Exposition South Dakota State University Apr 2008

2008 Little International Agricultural Exposition Catalog, Little International Agricultural Exposition South Dakota State University

Little International "Little I" Agricultural Exposition Catalogs

No abstract provided.

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Yersiniae Virulence Factors: Type Iii Secretion System, Jessica Blanco Apr 2008

Yersiniae Virulence Factors: Type Iii Secretion System, Jessica Blanco

Undergraduate Student Symposium

Several Gram-negative pathogenic bacteria have evolved a complex protein secretion system termed the Type Three Secretion System (TTSS) to deliver bacterial effector proteins into host cells that then modulate host cellular functions. These bacterial devices are evolutionarily related to the flagellar apparatus. Although the TTSSs are substantially conserved among different species, the effector molecules they deliver are species unique. There exist three human pathogenic Yersiniae. Yersinia enterocolitica and Yersinia pseudotuberculosis cause self-limiting gastro-enteric diseases and infect mesenteric lymph nodes, while Yersinia pestis is transmitted by fleas and can be aerosolized, causing the lethal disease known as plague (also know …

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The Use Of Cardiac Stem Cells For Myocardial Regeneration, Jenet George Apr 2008

The Use Of Cardiac Stem Cells For Myocardial Regeneration, Jenet George

Undergraduate Student Symposium

Cardiovascular disease is one of the leading killers in the western world. Because of its prevalence in society and the human heart’s questionable ability to repair itself, thousands of researchers have begun the lengthy process of myocardial research. They are analyzing different types of stem cells for their benefits and side effects, while trying to determine if the human heart is capable of regenerating itself. For the purposes of this literature review, several recent clinical and experimental trials will be analyzed to ascertain the feasibility of using cardiac stem cells in clinical practice. The harmful side effects of each main …

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The Relationship Between The Maze Coral (Meandrina Meandrites) Autumnal Bleaching Cycle And Seawater Temperature, Gulf Stream Reef, Boynton Beach, Florida, Naoko Kurata Apr 2008

The Relationship Between The Maze Coral (Meandrina Meandrites) Autumnal Bleaching Cycle And Seawater Temperature, Gulf Stream Reef, Boynton Beach, Florida, Naoko Kurata

Undergraduate Student Symposium

Seasonal coral bleaching has been observed and studied in tropical waters around the world. These studies have demonstrated that there is a strong correlation between anomalously elevated sea water temperature and coral bleaching events, however few studies have been performed on healthy corals during periods of normal sea water temperature fluctuation. Visible changes of pigmentation were used as a proxy measure of dinoflagellate densities in the maze coral Meandrina meandrites inhabiting the Gulfstream reef off Boynton Beach, Florida on 15 observations from mid-August 2007 to mid-January 2008. Unlike previous studies at this location, submersible temperature recorders were deployed, which provided …

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The Meaningless Of Life, Michael Bergbauer Apr 2008

The Meaningless Of Life, Michael Bergbauer

Undergraduate Student Symposium

Humankind has traditionally, throughout the ages, attempted to apply a meaning to its existence and believed that existence in and of itself, is a beautiful thing. In the spirit of Modernism, Beckett breaks with this tradition by asserting that existence is a bleak and squalid thing that has no meaning through his plays Waiting for Godot and Endgame. An analysis of these two plays reveals that life is inherently meaningless, but value in life is created by man by affirming it and practicing it. The reason the characters in Beckett’s plays are so miserable is because they take no …

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The Effects Of Zinc On Gene Expression In Saccharomyces Cerevisiae Using Polymerase Chain Reaction (Pcr) For Six Candidate Genes, Quratulain Hayat Apr 2008

The Effects Of Zinc On Gene Expression In Saccharomyces Cerevisiae Using Polymerase Chain Reaction (Pcr) For Six Candidate Genes, Quratulain Hayat

Undergraduate Student Symposium

Zinc (Zn) is one of the principle trace elements required in biological systems, with structural or enzymatical roles in hundreds of proteins. In humans, zinc deficiency has gradually come to be recognized as a clinically significant and common form of malnutrition, particularly in chronically ill patients. The clinical manifestations of zinc deficiency are diverse with effects on the immune system, appetite, and embryonic development. The regulation of zinc distribution remains a critical, unanswered question. The manner in which zinc is released from its tight binding sites in proteins and its transfer from one site to another are also unknown. In …

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The Development Of United States Special Forces In Response To The Perceived Cold War Threat, Michael E. Rosenzweig Apr 2008

The Development Of United States Special Forces In Response To The Perceived Cold War Threat, Michael E. Rosenzweig

Undergraduate Student Symposium

In the early period of the Cold War, the United States felt compelled to develop a Special Warfare capability in response to a perceived Soviet aggression. This “Special Warfare” capability was combined with psychological, unconventional and guerrilla tactics to foment social, economic and political unrest in the Soviet Union and its satellite states. The battle for the third world influence and prevention of the domino principle was primary forum for these clandestine units to operate to spread American ideals across the world. My symposium is designed to address three specific topics. The first is to address the perception of the …

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Synthesis Of A New Porphyrin Dendrimer And Its Potential Use As A Gadolinium Mri Agent, Karoline Korah Apr 2008

Synthesis Of A New Porphyrin Dendrimer And Its Potential Use As A Gadolinium Mri Agent, Karoline Korah

Undergraduate Student Symposium

A new porphyrin dendrimer was synthesized and characterized by reacting 4,4’,4’’,4’’’-(Porphine-5,10,15,20-tetrayl)tetrakis(benzoic acid) with a generation two (G2) dendrimer. Its coordination with lanthanides and gadolinium were investigated for its potential use as an MRI agent or as a new dendrimer-metalloporphyrin complex.

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Leap Of Faith, Chana F. Dukes Apr 2008

Leap Of Faith, Chana F. Dukes

Undergraduate Student Symposium

Leap of Faith is a retelling of the Sleeping Beauty fairytale and a nod to the original tale, before it was rearranged for the ears of children. I attempted to create a dream-like quality in the poem, using strong imagery and broken up stanzas to convey the impression of the dreaming child who is knocked from her slumber and into a harsh reality by her rape. I also attempted to create a sense of timelessness, because this is a story which occurs not once upon a time in a land far, far away, but all around us and throughout the …

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Points Of Consciousness, Iva Christina Marc Apr 2008

Points Of Consciousness, Iva Christina Marc

Undergraduate Student Symposium

The name of my poem is Points of Consciousness. The theme of Points of Consciousness is self love. The purpose of this poem is to celebrate the inner self and positive emotions when self love is present.

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My Vow, Amy Carol Harvey Apr 2008

My Vow, Amy Carol Harvey

Undergraduate Student Symposium

This poem’s collection of words has been chosen carefully in order to administer to the reader, a strong sense of dedication of love. The words induce the most significant emotions felt by the author on her wedding day. This poem was featured in the wedding program as a gift to the author’s husband on the day of their wedding.

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Letters Revealed A Literary Analysis Of Jane Austen’S Pride And Prejudice And Persuasion, Linnette Dobbs-Fuller Apr 2008

Letters Revealed A Literary Analysis Of Jane Austen’S Pride And Prejudice And Persuasion, Linnette Dobbs-Fuller

Undergraduate Student Symposium

This project is a literary analysis of two of Jane Austen’s novels: Pride and Prejudice and Persuasion. The paper is an attempt to reveal how Austen uses letters to establish and to maintain a link between her readers and her characters. The focus of this analysis is on the use of letters to maintain connections between characters over time and distances, to show growth or change in consciousness, and finally, to reveal the character of the person writing the letter.

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How To Create And Publish Your Own Music Videos Digitally, Adielle Silochan Apr 2008

How To Create And Publish Your Own Music Videos Digitally, Adielle Silochan

Undergraduate Student Symposium

This project, completed in the form of an original website coded in HTML and JavaScript, focuses on informing music artists about the basics of creating and publishing their own music videos using digital media. My research covers these four areas: video recording devices, video editing software, music recording devices, and publishing music videos on the Web. Concerning video recording devices, I include information to assist with choosing a digital camcorder to meet one’s needs (whether a novice or expert) and tips to help with filming. Concerning video editing software, I suggest software options for novices and experts and provide editing …

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Gentle Words Say Something Unbeautiful, Chana F. Dukes Apr 2008

Gentle Words Say Something Unbeautiful, Chana F. Dukes

Undergraduate Student Symposium

Gentle Words Say Something Unbeautiful came about when, in my creative writing class, we were given the assignment of using ugly words to say something pretty or pretty words to say something ugly. It has been through a couple of revisions since that original assignment, but that inspiration led me to create this pretty, melancholy poem which describes something abrupt and harsh; namely, a rape. The use of quatrains and the right alignment of the poem are intended to create the impression of repeated intrusion, D323wrongness, and grief.

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Easy To Love, Benita Williams Apr 2008

Easy To Love, Benita Williams

Undergraduate Student Symposium

Easy To Love is a short film about two graduate students who are engaged to be married. The couple comes to a crossroads when they decide to get blood tests, which may show that one of them has HIV. The film is directed by BeNita Williams. Other crew members include Cheryl White, Adam Walters, and Manuel Cedeno. James Frei is the starring actor.

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Consensual Sadomasochism, Briana O'Dowd Apr 2008

Consensual Sadomasochism, Briana O'Dowd

Undergraduate Student Symposium

Sadism, the desire to inflict pain, and masochism, the craving for pain, can be categorized as formal mental disorders, as per the DSMIV-TR, but only to the extent to which normal functioning is impaired by the acts and fantasies associated with them. Consensual sadomasochism carries with it a particular consideration as both participants desire to become the other’s erotic fantasy and indeed enjoy being in that role. Sadomasochism spans across nearly all demographics and time periods, having its origin around the emergence of philosophy, economics, and politics. Sadomasochism has been continuously looked down upon due to misunderstandings about the physiological …

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Austen’S Male Subordinates: Equality By Imbalance, Ryan Frabizio Apr 2008

Austen’S Male Subordinates: Equality By Imbalance, Ryan Frabizio

Undergraduate Student Symposium

In Jane Austen’s novels, the female characters are often the focus of critical study. This essay instead examines several minor male characters in her novels, such as Henry Crawford, Mr. Woodhouse, and Sir Walter Elliot, who deviate from conventional ideas of men in early eighteenth-century English society. The male characters studied lack independence or personal strength, and even lack dominance over female characters. However, they are still significant characters because they serve integral roles in the plot, and serve as vehicles for Austen’s ideas. The imbalances of power between Austen’s characters, even to the point of bringing male characters into …

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Amber’S Crush, Afroza Khan, Titina Gist, Elizabeth Gist Apr 2008

Amber’S Crush, Afroza Khan, Titina Gist, Elizabeth Gist

Undergraduate Student Symposium

“Amber’s Crush" is a comedic short film about a girl who has a condition called dyspraxia. At the mere age of seven Amber was in a traumatic accident resulting in a fatal injury to her head. Due to the traumatic head injury, Amber was diagnosed with a condition known as Dyspraxia. Dyspraxia is the inability to perform coordinated movements. After years of therapy and home schooling, Amber decides to return to real world and start college. But her past comes back to haunt her when she realizes that she can’t hide from her true self.

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