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Design And Construction Of A Novel Transpalpebral Ophthalmic Tonometer, Philippe R. Moinot

Theses

Glaucoma -- a degeneration of the optic nerve- is a leading cause of blindness which is primarily caused by large fluctuations in intraocular pressure (lOP) known as diurnal variations. Because these peak in the early morning dropping off rapidly, a self administrable and inexpensive lOP home testing procedure is highly desirable. The approach contained herein -- unlike traditional Goldman applanation tonometry which requires the use of ophthalmic anesthetics and complex diagnostic equipment- describes a novel lOP measurement method consisting of concavation of the cornea or sclera through the palpebra superior by the spherical tip of an optoelectronic photodetector suspended in …

Extreme Primary And Secondary Protein Structure Variability In The Chimeric Male-Transmitted Cytochrome C Oxidase Subunit Ii Protein In Freshwater Mussels: Evidence For An Elevated Amino Acid Substitution Rate In The Face Of Domain-Specific Purifying Selection, Eric G. Chapman, Helen Piontkivska, Jennifer M. Walker, Donald T. Stewart, Jason P. Curole, Walter R. Hoeh

Faculty Publications

Background

Freshwater unionoidean bivalves, and species representing two marine bivalve orders (Mytiloida and Veneroida), exhibit a mode of mtDNA inheritance involving distinct maternal (F) and paternal (M) transmission routes concomitant with highly divergent gender-associated mtDNA genomes. Additionally, male unionoidean bivalves have a ~550 bp 3' coding extension to the cox2 gene (Mcox2e), that is apparently absent from all other metazoan taxa.

Results

Our molecular sequence analyses of MCOX2e indicate that both the primary and secondary structures of the MCOX2e region are evolving much faster than other regions of the F and M COX2-COX1 gene …

Limnological Assistance For The Lake Mead National Recreation Area In Meeting The Challenge Of The Water 2025 Initiative: Annual Report, Period Ending May 31, 2008, Margaret N. Rees

Limnological Studies

Hiring: Limnologist Dr. Wai Hing (David) Wong was hired and officially reported to work on 5/15/2008.

Project 1 and Project 2: Dr. Wong has commenced work on Projects 1 and 2.

Project 3: Dr. Wong has commenced work on Project 3. A comprehensive zebra/quagga mussel bibliography has been completed and published to the 100th Meridian Web site. Six interagency, multi-disciplinary quagga mussel meetings have been held. A quagga mussel substrate project has been initiated and, through the coordination efforts of this project, two other studies have been selected and refined to help determine the ecological impacts of quagga mussel infestation …

Radiation-Induced Osteoporosis: Bone Quantity, Architecture, And Increased Resorption Following Exposure To Ionizing Radiation, Jeffrey Willey

All Dissertations

Skeletal complications from radiation therapy have been described for breast, brain, pelvic, and blood cancers. These problems include atrophy, fractures, and osteoradionecrosis. Improved survivorship rates of cancer patients receiving radiotherapy increases the importance of understanding the causal mechanisms and long-term effects of radiation-induced bone loss. One such long-term effect is bone fractures following radiation therapy for cancer treatment. The incidence of hip fractures is significantly increased following targeted radiotherapy for cancer. This decline in bone health can have a severe impact on the patient's functional capabilities. This damage to bone following irradiation is thought to involve damage to both osteoblasts …

Synthesis Of Corn-Derived Carbohydrate Derivatives As Effective Multifunctional Sunscreen, Xianhong Feng

Theses

The eighty-years-old sunscreen industry is sustained by the growing incidence of skin cancer and the continual exploration of skin aging. From the UVB-induced erythema to the UVA-induced persistent pigment darkening, scientists have used versatile methods to reveal that not only does UVB damage skin but also that longer wavelengths such as UVAIL (290nm ~ 340nm) and UVAL rays (340nm ~ 400nm) trigger skin cancer, premature skin aging and immunosuppression.

To meet a significant demand for improved photoprotection, a broad-spectrum sunscreen with a high extinction coefficient has been desired. As part of our ongoing studies on isosorbide-cinnamate derivatives, this work have …

Interactions Between Adult Human Mesenchymal Stem Cells And Nanofibrous Scaffolds Of Different Compositions, Lisamarie Moore

Theses

Stem cells have become increasingly important in the biomedical field because they have the potential to invade and regenerate damaged tissue. In particular, the bone marrow contains meesenchymal stem cells (MSCs) that have the capacity to differentiate into many cell lineages. The incorporation of MSCs within a multidimensional biomaterial provides a delivery vehicle to areas of injury. Natural and synthetic biomaterials can be made into scaffolds to represent different types of tissues. The ratio of synthetic to natural biomaterials in the scaffold influences the interaction with MSCs. This thesis created two different nanofibrous scaffolds by a process of electrospinning. The …

A Cytosolic Iron Chaperone That Delivers Iron To Ferritin, Haifeng Shi, Krisztina Z. Bencze, Timothy L. Stemmler, Caroline C. Philpott

Biochemistry and Molecular Biology Faculty Publications

Ferritins are the main iron storage proteins found in animals, plants and bacteria. The capacity to store iron in ferritin is essential for life in mammals, but the mechanism by which cytosolic iron is delivered to ferritin is unknown. Human ferritins expressed in yeast contain little iron. The human Poly r(C)-Binding Protein 1 (PCBP1) increased the amount of iron loaded into ferritin when expressed in yeast. PCBP1 bound to ferritin in vivo, and bound iron and facilitated iron loading into ferritin in vitro. Depletion of PCBP1 in human cells inhibited ferritin iron loading and increased cytosolic iron pools. Thus, PCBP1 …

Novel Candidate Genes Identified In The Brain During Nociception In Common Carp (Cyprinus Carpio) And Rainbow Trout (Oncorhynchus Mykiss), Siobhan C. Reilly, John P. Quinn, Andrew R. Cossins, Lynne U. Sneddon

Veterinary Science and Medicine Collection

Recent studies have demonstrated that teleost fish possess nociceptors that detect potentially painful stimuli and that the physiological properties of these fibres are markedly similar to those found in mammals. This finding led to suggestions of possible pain perception in fish, contrary to the view that the sensory response in these animals is limited to the spinal cord and hindbrain and as such is reflexive. Therefore, the aim of this study was to determine if the brain is active at the molecular level by using a microarray analysis of gene expression in the forebrain, midbrain and hindbrain of two fish …

2008-05-30, Board Of Regents, Murray State University

Board of Regents Meeting Minutes

No abstract provided.

Utilitarian Approaches For Multi-Metric Optimization In Vlsi Circuit Design And Spatial Clustering, Upavan Gupta

USF Tampa Graduate Theses and Dissertations

In the field of VLSI circuit optimization, the scaling of semiconductor devices has led to the miniaturization of the feature sizes resulting in a significant increase in the integration density and size of the circuits. At the nanometer level, due to the effects of manufacturing process variations, the design optimization process has transitioned from the deterministic domain to the stochastic domain, and the inter-relationships among the specification parameters like delay, power, reliability, noise and area have become more intricate. New methods are required to examine these metrics in a unified manner, thus necessitating the need for multi-metric optimization. The optimization …

Biogeographic Patterns Of Avian Malaria Parasites In The Lesser Antilles: Prevalence, Diversity, And Community Composition, Linda Maria Elenor Svensson

Theses

We investigated determinants of local and regional species richness and community composition of avian malaria parasites (Haemoproteus and Plasmodium) in the Lesser Antilles. Chapter 1 addresses the local parasite richness and community structure, or lack thereof, on Barbados. We found only two parasite lineages on this island, one of which was recovered from only 2 birds, which stands in stark contrast to the much higher diversity on other islands. In addition, we investigated what factors may explain the absence of avian malaria in southeastern Barbados, and found this area to be drier, warmer, and supporting less vegetation. Chapter 2 addresses …

The Effects Of Depressed Mood On Academic Outcomes In Adolescents And Young Adults, Robert Christopher Jones

USF Tampa Graduate Theses and Dissertations

The following dissertation investigates the relationship between depressed mood and academic performance (measured in terms of grade point average) in U.S. middle and high schools.

Utilizing data from AddHealth, the dissertation establishes Ordinary Least Squares, Two-Stage Least Squares (2SLS), and individual and sibling fixed effect regressions that attempt to control for confounding factors, including student motivation, personality characteristics, and parental inputs that are unobserved but may influence both mental health and achievement.

Study findings indicate that students who report feeling depressed do not perform as well academically as non-depressed students. Additionally, the degree of GPA impact increases with the severity …

Mustang Daily, May 29, 2008

Cal Poly Student Newspaper

Student newspaper of California Polytechnic State University, San Luis Obispo, CA.

Observer, Central Washington University

Student Newspaper

Student newspaper for Central Washington University for May 29, 2008

C.S. Lewis On Friendship, William L. Isley Jr.

Inklings Forever: Published Colloquium Proceedings 1997-2016

No abstract provided.

The Abolition Of Man In Retrospect, Paul E. Michelson

Inklings Forever: Published Colloquium Proceedings 1997-2016

No abstract provided.

'You Will Have No More Dreams; Have Children Instead' Or, What's A Nice Egalitarian Girl Like You Doing In A Book Like This?, Jennifer L. Woodruff Tait

Inklings Forever: Published Colloquium Proceedings 1997-2016

No abstract provided.

2008 Colloquium Program, Taylor University

Colloquium Programs

No abstract provided.

Estrogen Receptor (Er) Β Modulates Erα Responses To Estrogens In The Developing Rat Ventromedial Nucleus Of The Hypothalamus, Keith L. Gonzales, Marc J. Tetel, Christine J. Wagner

Faculty Research and Scholarship

The mechanisms by which estradiol exerts specific actions on neural function are unclear. In brain the actions of estrogen receptor (ER) α are well documented, whereas the functions of ERβ are not yet fully elucidated. Here, we report that ERβ inhibits the activity of ERα in an anatomically specific manner within the neonatal (postnatal d 7) brain. Using selective agonists we demonstrate that the selective activation of ERα in the relative absence of ERβ activation induces progesterone receptor expression to a greater extent than estradiol alone in the ventromedial nucleus, but not the medial preoptic nucleus, despite high ERα expression. …

2008 Printed Program, Taylor University

Colloquium Schedules

No abstract provided.

Vol.35 N.51 May 29th 2008, Brown Publishing Company

Black Voice News

No abstract provided.

Iwu's Equestrian Club Experiences Success In Competition, Kimberly Stabosz

News and Events (Discontinued Series)

No abstract provided.

Class Day To Honor The Class Of 2008

Sidney Kimmel Medical College Class Day

The Class Day program includes a list of speakers, awards given, officers of the graduating class, student council, and Clinic editors.

Central Florida Future, Vol. 40 No. 51, May 29, 2008

Central Florida Future

3% tuition increase approved by BOT; Fratting hard for a helping hand; Food sizzles in the student union; Students cheat for peak parking.

Pan-Arctic Patterns In Black Carbon Sources And Fluvial Discharges Deduced From Radiocarbon And Pah Source Apportionment Markers In Estuarine Surface Sediments, Marie Elmquist, Igor Semiletov, Laodong Guo, Örjan Gustafsson

Faculty Publications

A pan-arctic geospatial picture of black carbon (BC) characteristics was obtained from the seven largest arctic rivers by combining with molecular combustion markers (polycyclic aromatic hydrocarbons) and radiocarbon ((14)C) analysis. The results suggested that the contribution from modern biomass burning to BC ranged from low in the Yukon (8%) and Lena (5%) Rivers to high in the Yenisey River (88%). The Mackenzie River contributed almost half of the total arctic fluvial BC export of 202 kton a(-1) (kton = 10(9) g), with the five Russian-Arctic rivers contributing 10-36 kton a(-1) each. The (14)C-based source estimate of fluvially exported BC to …

Neuromyelitis Optica Pathogenesis And Aquaporin 4, David J. Graber, Michael Levy, Douglas Kerr, William F. Wade

Dartmouth Scholarship

Neuromyelitis optica (NMO) is a severe, debilitating human disease that predominantly features immunopathology in the optic nerves and the spinal cord. An IgG1 autoantibody (NMO-IgG) that binds aquaporin 4 (AQP4) has been identified in the sera of a significant number of NMO patients, as well as in patients with two related neurologic conditions, bilateral optic neuritis (ON), and longitudinal extensive transverse myelitis (LETM), that are generally considered to lie within the NMO spectrum of diseases. NMO-IgG is not the only autoantibody found in NMO patient sera, but the correlation of pathology in central nervous system (CNS) with tissues that normally …

An Investigation Of The Online Learning Environment In Higher Education Through The Observations And Perceptions Of Students Of Color, Marie Adele Boyette

USF Tampa Graduate Theses and Dissertations

A need exists to gain a better understanding of how the online learning environment found in higher education is perceived by students of color. The research completed for this dissertation explored student participation in the online learning environment in higher education by examining the observations and perceptions of students of color. Along the way, the process of the research journey drew attention to the lack of inclusion of students of color in the literature and data collected about online learning, and pointed to the existence of the digital divide and its impact on graduate students of color and their participation …

Um Hires Next College Of Arts And Sciences Dean, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.

The George-Anne, Georgia Southern University

The George-Anne

• Police Investigations Continue After Armed Robbery
• News
• Briefs
• Features
• Sports

Spfc Research Conference Guide 2008, Seattle Pacific University

School of Psychology, Family, and Community Research Conference

Full 2008 conference guide with descriptions of each poster or paper presented by students in Seattle Pacific University's School of Psychology, Family, and Community's annual research conference.