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Full-Text Articles in Entire DC Network
"I Will Learn You Something If You Listen To This Song": Southern Women Writers' Representations Of Music In Fiction, Courtney George
"I Will Learn You Something If You Listen To This Song": Southern Women Writers' Representations Of Music In Fiction, Courtney George
LSU Doctoral Dissertations
This dissertation offers a rhetorical analysis of the formation of women’s memory, history, and communities in intersections of musical and literary expression in the American South, a region graced with a vital but underexamined tradition of female musicianship. Recent scholars have deconstructed the imagined narrative of southern culture as static, patriarchal, and white to uncover alternative stories and cultures that exist outside of canonical literature. This project significantly expands current understandings of these conflicting narratives by investigating how women writers recall, reclaim, and re-envision women’s roles in southern music to challenge, comply, and/or identify with women’s prescribed place in the …
Environment, Labor, And Race: An Historical Geography Of St. Tammany Parish, Louisiana, 1878-1956, Amy Rhiannon Sumpter
Environment, Labor, And Race: An Historical Geography Of St. Tammany Parish, Louisiana, 1878-1956, Amy Rhiannon Sumpter
LSU Doctoral Dissertations
St. Tammany Parish, Louisiana, is known as a white suburb of New Orleans. It also has a well-known history as a health resort for wealthy New Orleanians during the summer months, particularly during yellow fever outbreaks in the late nineteenth- and early twentieth centuries. This research investigates the historical geography of this parish in terms of race and attempts to answer the question of how St. Tammany became an attractive place for the development of white subdivisions in the 1950s. I uncover the connections between race, labor, the environment, and political culture of the parish from 1878—the year Reconstruction ended—to …
Retro Models Of The Cisplatin-Dna Cross-Link With Carrier Ligands Having Sp2 N-Donor Triazine Rings, Vidhi Maheshwari
Retro Models Of The Cisplatin-Dna Cross-Link With Carrier Ligands Having Sp2 N-Donor Triazine Rings, Vidhi Maheshwari
LSU Doctoral Dissertations
Rapid rotation of guanine base derivatives about Pt–N7 bonds results in fluxional behavior of models of the key DNA intrastrand G–G cross-link leading to anticancer activity of Pt(II) drugs (G = deoxyguanosine). This behavior impedes the characterization of LPtG2 models (L = one bidentate or two cis-unidentate carrier ligands; G = guanine derivative). The objective of this study is to understand the types of conformers formed as L is systematically varied. This work, relevant to Pt(II) anticancer drugs, has evolved from published studies with sp3 N-ligands (e.g., 2,2'-bipiperidine), to C2 symmetrical or unsymmetrical sp2 N-ligands having pyridine and/or triazine rings. …
Native Spiritualities As Resistance: Disrupting Colonialism In The Americas, Kirstin Lea Squint
Native Spiritualities As Resistance: Disrupting Colonialism In The Americas, Kirstin Lea Squint
LSU Doctoral Dissertations
This project analyzes eight novels which represent revolt or resistance by varied Native peoples against the European and Euro-American colonization of the Americas. I take a comparative approach to literatures of the Americas because of the dearth of research examining the literatures of both continents side by side, particularly literatures by and about Indigenous Americans. Chapter One introduces the theoretical bases for the project, including colonial and postcolonial theories, Native American literary theories, and aesthetic concerns specific to American Indian literatures. The second chapter is a comparative analysis of Miguel Angel Asturias’s Men of Maize and Leslie Marmon Silko’s Almanac …
Phylogeogaphy Of Nothoprocta Tinamous And The The Phylogeny Of The Tinamidae, Thomas Valqui
Phylogeogaphy Of Nothoprocta Tinamous And The The Phylogeny Of The Tinamidae, Thomas Valqui
LSU Doctoral Dissertations
Understanding how diversity is attained and maintained is one of the central questions in biology. In the Neotropics most attention has centered on the Amazonian lowlands, despite the recognized importance of the role of the Andes in South American diversity. In this dissertation, I address the question by using Nothoprocta tinamous as a model case for examining diversification in the Andes. As a group, they are a manageable size, they exhibit near-restriction to the Andes, they show multi-species parapatric distributions, and they have presumed limited dispersal ability. These are all useful attributes for a system to study speciation and diversification. …
Using Color Infrared Imagery To Detect Sooty Mold And Fungal Pathogens Of Glasshouse-Propagated Plants, Kenneth R. Summy, Christopher R. Little
Using Color Infrared Imagery To Detect Sooty Mold And Fungal Pathogens Of Glasshouse-Propagated Plants, Kenneth R. Summy, Christopher R. Little
School of Integrative Biological & Chemical Sciences (Formerly Dept. of Biology)
Fungi are major biotic constraints for optimum production and quality of glasshouse plants. When plants are infested with sooty mold (Capnodium spp.) or infected with pathogens, the reflected wavelengths of the electromagnetic spectrum are altered. Spectroradiometric measurements and color infrared (CIR) images of control, honeydew- coated, and sooty mold-infested saplings and individual leaves from trifoliate orange (Poncirus trifoliata), sour orange (Citrus aurantium), ‘Valencia’ orange (C. sinensis), and ‘Bo’ tree (Ficus religiosa) were obtained. Grapefruit saplings and individual leaves infected with Mycosphaerella citri (greasy spot) were imaged under glasshouse conditions. Similarly, muskmelon foliage showing low and high levels of powdery mildew …
Neptunia Plena (Fabaceae: Mimosoideae) Rediscovered In Texas, Alfred Richardson, Ken King
Neptunia Plena (Fabaceae: Mimosoideae) Rediscovered In Texas, Alfred Richardson, Ken King
School of Integrative Biological & Chemical Sciences (Formerly Dept. of Biology)
On October 17, 1938, Robert Runyon collected a specimen of Neptunia plena from a shallow pond south of Armstrong in Kenedy County, Texas. No subsequent collections from Texas have been reported . It was assumed that it was not a permanent member of our flora. On October 27, 2007, a population of N. plena was found near the same locality.
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El 17 de octubre de 1938, Robert Runyon recogió un espécimen de Neptunia plena de una charca somera de Armstrong en el condado de Kenedy, Tejas. No se ha encontrado ninguna colección posterior de Tejas. Fue asumido que no …
Evolutionary Origins, Diversification, And Biogeography Of Liver Flukes (Digenea, Fasciolidae), Wael M. Lotfy, Sara V. Brant, Randy J. Dejong, Hoa Le Thanh
Evolutionary Origins, Diversification, And Biogeography Of Liver Flukes (Digenea, Fasciolidae), Wael M. Lotfy, Sara V. Brant, Randy J. Dejong, Hoa Le Thanh
University Faculty Publications and Creative Works
Fasciolid flukes are among the largest and best known digenetic trematodes and have considerable historical and veterinary significance. Fasciola hepatica is commonly implicated in causing disease in humans. The origins, patterns of diversification, and biogeography of fasciolids are all poorly known. We have undertaken a molecular phylogenetic study using 28S, internal transcribed spacer 1 and 2 (ITS-1 and ITS-2) of nuclear ribosomal DNA, and mitochondrial nicotinamide dehydrogenase subunit 1 (nad1) that included seven of the nine recognized species in the family. The fasciolids examined comprise a monophyletic group with the most basal species recovered from African elephants. We hypothesize fasciolids …
Growth And Properties Of Metal-On-Metal Nanostructures: Ag On Cu(110) And Co On Ag(110), Indrajith Chandima Senevirathne
Growth And Properties Of Metal-On-Metal Nanostructures: Ag On Cu(110) And Co On Ag(110), Indrajith Chandima Senevirathne
LSU Doctoral Dissertations
Heteroepitaxial nanostructures have a diverse array of applications and show novel phenomena that arise from the exotic physics exhibited in reduced dimensions. We have investigated two nano-structured systems in order to gain insights into the dynamics of their nucleation, growth and have observed striking differences, due in part to a competition between lattice strain, surface and interfacial free energies. When Ag is deposited on clean, single-crystal Cu(110), it initially wets the surface with a (111) monolayer, and spontaneously nucleates nanowires as the coverage is increased. The nanowires nucleate at defects and step edges and grow aligned along the [1–10] direction. …
Numerical Simulations Of Flow And Mass Transport In Micro-Fluidic Components For Modular Bio-Analytic Chip Applications, Sudheer D. Rani
Numerical Simulations Of Flow And Mass Transport In Micro-Fluidic Components For Modular Bio-Analytic Chip Applications, Sudheer D. Rani
LSU Doctoral Dissertations
Microfluidics has received a great deal of attention in the past decade. The ability of modular microfluidic chips to miniaturize integrate chemical and biological systems (µTAS) can be greatly productive in terms of cost and efficiency. During the design of these modular devices, misalignment of materials, geometrical or both is one of the most common problems. These misalignments can have adverse effect in both pressure driven and electrokinetically driven flows. In the present work, Numerical Simulations have been performed to study the effect of material and geometrical mismatch on the flow behavior and species progression in microfluidic interconnects. In the …
Characterization And Comparison Of Cell Frequency, Growth, And Multipotential Differentiation Of Adult Mesenchymal Stromal Cells Derived From Equine Bone Marrow And Adipose Tissue, Martin Andreas Vidal
Characterization And Comparison Of Cell Frequency, Growth, And Multipotential Differentiation Of Adult Mesenchymal Stromal Cells Derived From Equine Bone Marrow And Adipose Tissue, Martin Andreas Vidal
LSU Doctoral Dissertations
Equine bone marrow-derived mesenchymal stromal cells (MSCs) and adipose tissue-derived stromal cells (ASCs) were compared for frequency within their respective tissues, cell doubling characteristics and differentiation multipotential in culture based on histochemical staining and compositional analysis. Equine MSCs and ASCs from young adult horses were harvested and isolated from sternal bone marrow and supragluteal subcutaneous adipose tissue, respectively, and grown up to passage 10 (P10) to determine cell doubling characteristics. Limit dilution assays were performed on primary and passaged (P2, P4) MSCs and ASCs to determine the frequency of colony forming units with a fibroblastic phenotype (CFU-F), and the frequency …
Novel Methods For The Control Of Phlebotomine Sand Flies (Diptera: Psychodidae), Thomas Michael Mascari
Novel Methods For The Control Of Phlebotomine Sand Flies (Diptera: Psychodidae), Thomas Michael Mascari
LSU Doctoral Dissertations
In arid and semi-arid parts of the Old World, Phlebotomus paptasi is a significant biting pest of man and is the primary vector of Leishmania major, the causative agent of zoonotic cutaneous leishmaniasis (ZCL). Phlebotomus papatasi exhibits a close association with the burrowing rodents that serve as the reservoirs of L. major. Rodent burrows are considered to be the primary habitat of immature P. papatasi in ZCL foci, and sand fly larvae have been observed feeding on rodent feces. In laboratory studies, five insecticides (diflubenzuron, novaluron, methoprene, pyriproxyfen, or ivermectin) were incorporated into the diet of Syrian hamsters and evaluated …
Neuropsychological Performance And Dementia Symptoms In A Hiv Positive Population, Kathleen E. Kendra
Neuropsychological Performance And Dementia Symptoms In A Hiv Positive Population, Kathleen E. Kendra
LSU Doctoral Dissertations
Acquired immune deficiency syndrome (AIDS) is an infectious disease caused by human immunodeficiency virus (HIV), which affects millions of individuals worldwide. This syndrome is associated with many medical complications. Fortunately, patients with HIV and AIDS have longer life expectancy than in past decades with HIV and AIDS; however, the risk of cognitive impairment is greater in this population. Identification of dementia due to HIV/AIDS by health care professionals is hampered by the unclear relationship between cognitive functioning and HIV-related health status in the HIV/AIDS research literature. For the current study, individuals with HIV/AIDS who are symptomatic with infection but do …
Effects Of Induced Acute Phase Response In Ewes On Early Embryo Survival, Tina Lynn Dow
Effects Of Induced Acute Phase Response In Ewes On Early Embryo Survival, Tina Lynn Dow
Graduate Theses, Dissertations, and Problem Reports (ETD)
Early pregnant ewes, 5/6 day post coitus (dpc) were used as a model to study early embryonic loss via gram-positive bacterial infections, such as mastitis. Ewes 5/6 dpc were injected with a gram-positive bacteria cell wall component, peptidoglycan-polysaccharide (PG-PS), to induce an innate immune system acute phase response (APR). The induction of the APR and its reactant molecules, such as cytokines and acute phase proteins (APP), were initiated to study their effects on embryonic loss. Twenty Suffolk ewes were synchronized for estrus and bred by fertile rams. At 4 dpc ewes were anesthetized and catheters were surgically placed in the …
Thermal Rearrangement Of 4-Aryl-4-Hydroxy-2-Cyclobuten-1-Ones And Application Of The Methodology In The Formation Of Benzofuronaphthoquinones And Benzocarbazolequinones, Kimberly Denise Fisher
Thermal Rearrangement Of 4-Aryl-4-Hydroxy-2-Cyclobuten-1-Ones And Application Of The Methodology In The Formation Of Benzofuronaphthoquinones And Benzocarbazolequinones, Kimberly Denise Fisher
Graduate Theses, Dissertations, and Problem Reports (ETD)
Cyclobutenediones have proven useful as starting materials for synthesis of highly functionalized biologically relevant molecules. The rearrangement of cyclobutendiones has a wide synthetic scope and can be utilized as a key step in the construction of quinones, benzo[o]isoxazoles, and 3-methylenoxoindoles having a variety of substitution patterns. Construction of these molecules involves thermolysis of 4-hydroxy-2,4-di-aryl-2-cyclobutenones derived from squaric acid ester. In each of the cases the mechanism proceeds through an initial ring opening of the cyclobutene to afford a ketene intermediate that subsequently undergoes a ring closure with various intermolecular nucleophiles. This methodology has been utilized in the construction of an …
Lidar, Gis, And Multivariate Statistical Analysis To Assess Landslide Risk, Horseshoe Run Watershed, West Virginia, Kory M. Konsoer
Lidar, Gis, And Multivariate Statistical Analysis To Assess Landslide Risk, Horseshoe Run Watershed, West Virginia, Kory M. Konsoer
Graduate Theses, Dissertations, and Problem Reports (ETD)
Current stream restoration practices focus on stabilizing banks, transporting sediment, and creating aquatic habitats. However, only channel morphology data are collected prior to typical restoration project designs. A more thorough approach to assessing restoration projects incorporates the geomorphology of the contributing hillslopes within the watershed. For this project, a landslide risk assessment was conducted for Horseshoe Run watershed in West Virginia using LiDAR data, GIS, and multivariate statistical analysis to provide the restoration projects with information concerning the geomorphology of the hillslopes and identify areas of greater risk for slope failure. A landslide inventory map was created using field observations …
Thresholds And Tolerance Of Physical Pain Among Young Adults Who Engage In Self-Injury, Katrina Mccoy
Thresholds And Tolerance Of Physical Pain Among Young Adults Who Engage In Self-Injury, Katrina Mccoy
Graduate Theses, Dissertations, and Problem Reports (ETD)
Prevalence rates of non-suicidal self-injury among college students ranges from 17% to 38%. Research indicates that individuals with borderline personality disorder (BPD) who self-injure sometimes report an absence of pain during self-injury. Furthermore, self-injury in the absence of pain has been associated with more frequent suicide attempts. The present study examined pain thresholds and tolerance among 44 college students (11 self-injurious and 33 non-self-injurious). Pain thresholds and tolerance were measured using an algometer pressure device which has been used to produce pain previous laboratory research. Self-injurious participants had higher pain tolerances than those who do not engage in self-injury. In …
Electrochemical Fabrication Of Auco Nanostructures, Maoshi Guan
Electrochemical Fabrication Of Auco Nanostructures, Maoshi Guan
LSU Doctoral Dissertations
Electrodeposited Au/CoAu multilayered nanowires are materials with alternating layers of Au and CoAu in a wire where the layer thickness and wire diameter are nanometer size. They can be used for different applications. For example, the wires may exhibit giant magnetoresistance (GMR), a change in the materials resistance with a magnetic field, having applications as a sensor material for microdevices. If Co is etched from CoAu nanowires, rough, porous gold nanostructures will be left behind, which could be used as novel catalysts. In this study, the electrodeposition of Au/CoAu multilayered nanowires and nanotubes in nanoporous templates was explored from a …
Chemotactic And Inflammatory Responses To And Recognition Of Encephalitozoon Spp. Of Microsporidia, Jeffrey Lynn Fischer
Chemotactic And Inflammatory Responses To And Recognition Of Encephalitozoon Spp. Of Microsporidia, Jeffrey Lynn Fischer
LSU Doctoral Dissertations
Microsporidiosis is an emerging disease among immunocompromised individuals who often present with chronic diarrhea. The intracellular, eukaryotic parasites responsible for this pathology can often disseminate, causing multiorgan infections. Dissemination of these pathogens is believed to occur through vehicular spread by macrophages. The macrophage response to microsporidia is poorly understood. The information, described herein, is focused on defining the host-pathogen interaction and subsequent inflammatory response in human monocyte-derived-macrophages (MDM) against Encephalitozoon spp. of microsporidia. Initial studies were designed to better define the infection kinetics in MDM using various microscopic analysis and novel staining approaches. Spore adherence and uptake occurs within the …
High-Performance Liquid Chromatographic Determination Of Asiatic Acid In Human Plasma, Phensri Thongnopnua
High-Performance Liquid Chromatographic Determination Of Asiatic Acid In Human Plasma, Phensri Thongnopnua
The Thai Journal of Pharmaceutical Sciences
Asiatic acid, an active metabolite of asiaticoside, is one of the biological active triterpenoids in Centella asiatica. A single liquid-liquid extraction and high-performance liquid chromatographic (HPLC) method have been developed and validated for the ...
Perioperative Music And Its Effects On Anxiety, Hemodynamics, And Pain In Women Undergoing Mastectomy, Pamela Gail Binns-Turner
Perioperative Music And Its Effects On Anxiety, Hemodynamics, And Pain In Women Undergoing Mastectomy, Pamela Gail Binns-Turner
All ETDs from UAB
The study purpose was to examine the effects of a perioperative music intervention on changes in mean arterial pressure (MAP), heart rate (HR), anxiety, and pain in women with a diagnosis of breast cancer undergoing mastectomy surgery. The convenience sample included 30 women between the ages of 42 and 70 who were undergoing mastectomy in a large urban hospital in the southern United States. Exclusion criteria included male gender, psychiatric disorder, use of psychotropic medications, cognitive mental disability, and American Society of Anesthesiologists (ASA) status 4 or greater. In a quasiexperimental, repeated measures design, participants were randomized equally into music …
Effects Of Hexosamine Biosynthesis On An In Vitro Model Of Cardiacischemia, Voraratt Champattanachai
Effects Of Hexosamine Biosynthesis On An In Vitro Model Of Cardiacischemia, Voraratt Champattanachai
All ETDs from UAB
Increased levels of protein O-linked-N-acetylglucosamine (O-GlcNAc) have been correlated with increased cell survival following stress. Therefore the goal of this study was to determine whether enhanced flux through the hexosamine biosynthesis pathway (HBP), which leads to elevated levels of O-GlcNAc, improved the tolerance of isolated neonatal rat ventricular myocytes (NRVMs) to ischemia/reperfusion (I/R) injury. NRVMs were exposed to hypoxic medium for 4 hours, followed by oxygenated complete medium for 16 hours. Acute treatment with 5 mM glucosamine showed an increase in viability and decreased both necrosis and apoptosis following I/R. Glucosamine increased O-GlcNAc levels maximally at 2 hours and went …
Evaluation Of Pre And Post Treatment Filtration Performance Of Kinetico Macrolite® Ceramic Media Compared To Traditional Sand/Anthracite And Gac Filters In Drinking Water Treatment Process, Jeff Cochran
All ETDs from UAB
This study was conducted in conjunction with the Birmingham Water Works Board to evaluate Kinetico ceramic filter media against GAC (Granular Activated Carbon) and Sand/Anthracite filters. The Birmingham Water Works Board Water Treatment Pilot Plant was located and operated on the Shades Mountain Filter Plant (SMFP) premises. The evaluation was conducted in three phases: plant matching, plant optimization, and pre-filter testing. The initial phase called for determining the best combination of Kinetico Macrolite Ceramic media to match or outperform the existing Sand/Anthracite dual media filters located at SMFP. At the end of the testing it was determined that 18 inches …
Structural And Functional Properties Of Human Αa-Crystallin, Jose Mauro Chaves
Structural And Functional Properties Of Human Αa-Crystallin, Jose Mauro Chaves
All ETDs from UAB
The three specific aims of the project were: (1) compare effects of deamidation alone (i.e., αA-N101D, αA-N123D, αA-N101/123D), truncation alone (αA-NT mutant [deletion of residue no. 1-63], or αA-CT mutant [deletion of residue no. 140-173]), or both truncation plus deamidation on structural and functional properties of human lens αA-crystallin; (2) identify components of complexes in the water soluble-high molecular weight (WS-HMW) proteins of normal aging and cataractous human lenses; and (3) determine interactions among WT-αA, αA-NT and αA-CT crystallin species with filensin and phakinin (beaded filament proteins) in vitro. The comparative structural and functional differences between αA-deamidated and/or truncated mutants …
The Reproductive Cycle Of Lytechinus Variegatus (Echinodermata: Echinoidea) From The Florida Panhandle, Adele Cunningham
The Reproductive Cycle Of Lytechinus Variegatus (Echinodermata: Echinoidea) From The Florida Panhandle, Adele Cunningham
All ETDs from UAB
The range of the regular echinoid Lytechinus variegatus extends from the Carolinas along the US Atlantic coast to Brazil. To our knowledge, the present study is the northernmost study to examine histology of the reproductive cycle of Lytechinus variegatus. From April 2001 to September 2003, at intervals of about 4-6 weeks, L. variegatus with an average diameter of 45 mm were collected at Eagle Harbor in St. Joseph’s Bay, Florida.. A staging system for gamete development and maturation based on histology of the gonad was devised for female and male L. variegatus. Histology indicated a period of nutrient storage and …
Human-Centered Semantic Retrieval In Multimedia Databases, Xin Chen
Human-Centered Semantic Retrieval In Multimedia Databases, Xin Chen
All ETDs from UAB
The research described in this dissertation has proposed a human-centered retrieval framework that can automatically retrieve multimedia data based on their semantic content. In particular, the framework queries and searches images and videos in a multimedia database according to their visual content. In order for computers to understand the semantic contents of images and videos, human guidance is necessary. By incorporating the user’s Relevance Feedback (RF) on the retrieval results into the learning and retrieval mechanism, the semantic gap between humans and computers can be gradually bridged. High-dimensional feature vectors of multimedia data can cause a dramatic increase in computation …
Microbial Biofilm Attachment To Caenorhabditis Elegans, Kevin Drace
Microbial Biofilm Attachment To Caenorhabditis Elegans, Kevin Drace
All ETDs from UAB
The closely related bacterial species Xenorhabdus nematophila, Yersinia pestis and Y. pseudotuberculosis make biofilms capable of adhering to the head of the model nematode Caenorhabditis elegans. Y. pestis uses biofilms to block the digestive tract of its vector, the flea, in order to enhance its efficiency of transmission. I investigated the role of biofilms in X. nematophila and found that, like its Yersinia sp. counterparts, production of biofilm requires a four-gene operon: hmsHFRS. X. nematophila is an insect pathogen and an obligate symbiont of the nematode Steinernema carpocapsae. However, an X. nematophila hmsH mutant that failed to make biofilms on …
Examining Pre-Service Instructors' Use Of Powerpoint Based On Pre-Service Students' Perceptions: A Mixed Methods Study, Jennifer Fritschi
Examining Pre-Service Instructors' Use Of Powerpoint Based On Pre-Service Students' Perceptions: A Mixed Methods Study, Jennifer Fritschi
All ETDs from UAB
This study explored pre-service instructors’ use of PowerPoint based on pre-service students’ perceptions, and it identified pre-service students’ perceptions of the efficacy of specific elements of PowerPoint design and delivery. The effectiveness of various elements of PowerPoint design and delivery was based on an extensive literature review and was framed on the Cognitive Theory of Multimedia (Mayer, 2000). The findings of the study identified pre-service instructors’ practices and pre-service students’ perceptions of the effectiveness of specific elements of design and delivery and were then compared with what research and expert literature purported were effective. This one year study was conducted …
Analysis Of The Role Of Fcrl5 And Figlers In B Cell Development, Signaling, And Malignancy, Christopher L. Haga
Analysis Of The Role Of Fcrl5 And Figlers In B Cell Development, Signaling, And Malignancy, Christopher L. Haga
All ETDs from UAB
The regulation of signaling and migration is critical to B lymphocyte development, activation, and proliferation. This dissertation reports a functional role for Fc receptor-like molecule 5 (FCRL5), a B cell specific member of the Fc receptor-like family of molecules, and the discovery of a novel family of conserved transmembrane proteins with fibronectin, immunoglobulin, and leucine-rich repeat domains (FIGLER) expressed in bone marrow and B lineage cells. Until now, the signaling potential of FCRL5 was unknown. A panel of FcRIIB/FCRL5 chimeric receptors were created and expressed in a B cell line lacking endogenous FcRIIB. Coligation of the chimeric receptor with the …
Role Of The Gm/Gn Glycoprotein Complex In The Final Assembly And Egress Of The Human Cytomegalovirus (Hcmv), Magdalena Anna Krzyzaniak
Role Of The Gm/Gn Glycoprotein Complex In The Final Assembly And Egress Of The Human Cytomegalovirus (Hcmv), Magdalena Anna Krzyzaniak
All ETDs from UAB
HCMV consists of a dsDNA genome enclosed by, an icosahedral capsid surrounded by a layer of tegument proteins; the virion structure is enclosed in a lipid envelope rich in virus expressed glycoproteins. The HCMV envelope contains an incompletely defined number of glycoproteins. The glycoprotein M (gM) and glycoprotein N (gN) form a gM/gN protein complex which is the most abundant protein component of the HCMV envelope. Recent studies have indicated that deletion of the viral gene encoding either gM or gN is lethal for HCMV. The gM C-terminal cytoplasmic tail (gM-CT) revealed an acidic cluster and a tyrosine-based trafficking motifs. …