Digital Commons Network^™

Extreme Makeover - Surrogacy Edition: Reassessing The Marriage Requirement In Gestational Surrogacy Contracts And The Right To Revoke Consent In Traditional Surrogacy Agreements, Jamie L. Zuckerman

Nova Law Review

No abstract provided.

Wyche V. State: A Case Analysis, Milton Hirsch

Nova Law Review

No abstract provided.

Agricultural Systems: Agroecology And Rural Innovations For Development [Book Review], Charles A. Francis

Department of Agronomy and Horticulture: Faculty Publications

To welcome yet another book on sustainable development, a reviewer must look for what is unique and what adds value to the volumes already published. In Agricultural Systems, editors Sieglinde Snapp and Barry Pound have assembled a collection of chapters that goes beyond the usual praise and criticism of the green revolution and the focus on economic development. Their book provides a first-hand story by people with lengthy experiences in the field, especially in Africa, who have developed and tested grassroots, participatory development approaches. The result is a valuable set of principles, strategies and case studies that paint a new …

Reducing Hiv/Aids In Young People In Sub-Sahara Africa: Gaps In Research And The Role Of Theory, Kristien Michielsen, Marleen Bosmans, Marleen Temmerman

Obstetrics and Gynaecology, East Africa

This paper discusses the role of education in preventing HIV in children and young people in sub-Sahara Africa and presents the results of policy advisory research conducted on behalf of the Belgian Development Cooperation. The research consisted of a literature review and a field study in Rwanda. Relative to the high number of HIV prevention activities in sub-Sahara Africa, there is a limited number of scientific data on HIV risk reduction interventions for young people in this region. Longitudinal studies are especially scarce. Preliminary results show that many interventions have only a marginal impact on reducing sexual risk behaviour. Factors …

Bgsu Graduate College 2008-2010 Catalog, Bowling Green State University

Course Catalogs

Bowling Green State University graduate catalog for 2008-2010.

Shall We Reinvent Our 100 Year Old Denomination? Surveying Organizational Models, Kenneth Crow, Richard Houseal, Stan Ingersol, Dale Jones

Journal of the American Society for Church Growth

David Moberg has described the life cycle of religious organizations in The Church as a Social Institution. His model suggests five predictable stages. FIGURE 1 In the beginning of the ascending curve there is a phase of incipient organization characterized by a negative reaction to existing churches, emotional enthusiasm for the new church, and diffused leadership. Second, as the age and effectiveness of the organization increase, there is a phase of formal organization characterized by membership commitments, specification of goals, symbolic separation from the larger society, and a gradual move from charismatic leaders to rational or bureaucratic leaders. Third, as …

Laboratory Diagnosis Of Clostridium Difficile In The Republic Of Ireland: A Survey Of Irish Microbiology Laboratories., Denise Drudy, F. Fitzpatrick, A. Oza, A. Gilleece, A. M. O’Byrne

Articles

The Health Protection Surveillance Centre (HPSC) established a group to produce national guidelines for Clostridium difficile in Ireland in 2006. A laboratory questionnaire was distributed to determine current C. difficile diagnostic practices. Twenty-nine out of 44 laboratories providing C. difficile diagnostic services to 34 hospitals responded. Twenty-five out of 29 (86%) laboratories processed specimens for C. difficile and four (13.8%) forwarded specimens to another laboratory. Sixteen laboratories (64%) processed specimens for other healthcare facilities. None routinely examined stool for C. difficile, seven (28%) examined specimens only when requested to do so and 18 (72%) used specific selection criteria, including testing …

Cover And Contents

Turkish Journal of Mathematics

No abstract provided.

Coping With Everyday Classism: Exeriences Of Low-Income People In A Southeastern Rural Community, Susan Faye Ritz

Open Access Dissertations

The present research provided an in-depth look at experiencing and coping with everyday classism in a sample of low-income. people in a mid-size southeastern rural United States community. The study employed a qualitative methodology consisting of semi-structured interviews and analyzing the collected data using Grounded Theory Method. Of 50 participants selected for an interview, 40 described experiences with classism, each discussing two incidents, for a total of 80 incidents shared. Seven of the remaining 10 participants felt that they had not experienced class ism, but at the same time, they provided insight into one proactive coping strategy that they appeared …

Design And Evaluation Of Nucleoside Derivatives For Targeted Drug Delivery And Therapeutic Applications, Hitesh Kumar Agarwal

Open Access Dissertations

2',3'-Dideoxynucleoside analogs are commonly used as anti-HIV, anti-HBV, and anti-cancer drugs. Despite of their potent activities, there are some major limitations in using 2',3'-dideoxynucleosides as therapeutic agents. The nucleosides have usually poor cellular uptake because of their hydrophilic nature. Some of the nucleoside analogs, such as anti-HIV agents, become ineffective after multiple administrations because of the development of the drug resistance, and therefore they must be administered in combination therapy. It is hard to deliver the nucleoside analogs to a particular tissue for site specific targeting. Furthermore, nucleoside analogs undergo three intracellular phosphorylation steps to become active. The first phosphorylation …

Regulated Expression Of Adenoviral Vectors-Based Gene Therapies: Therapeutic Expression Of Toxins And Immune-Modulators, James Curtin, Marianela Candolfi, Mariana Puntel, Weidong Xiong, Akm Ghulam Muhammad, Kurt Kroeger, Sonali Mondkar, Chunyan Liu, Niyati Bondale, Pedro Lowenstein, Maria Castro

Articles

Regulatable promoter systems allow gene expression to be tightly controlled in vivo. This is highly desirable for the development of safe, efficacious adenoviral vectors that can be used to treat human diseases in the clinic. Ideally, regulatable cassettes should have minimal gene expression in the "OFF" state, and expression should quickly reach therapeutic levels in the "ON" state. In addition, the components of regulatable cassettes should be non-toxic at physiological concentrations and should not be immunogenic, especially when treating chronic illness that requires long-lasting gene expression. In this chapter, we will describe in detail protocols to develop and validate first …

From John F. Kennedy’S 1960 Campaign Speech To Christian Supremacy: Religion In Modern Presidential Politics, Stephen A. Newman

Articles & Chapters

No abstract provided.

A Transcriptome Comparison Of Caenorhabditis Elegans Cultured In Laboratory And Soil-Like Environments, Richard A. Roy

Master's Theses and Capstones

Caenorhabditis elegans has been the subject of numerous microarray experiments designed to help understand gene expression and function. Many such experiments have assessed the animal's transcriptional response to simple perturbations of the traditional laboratory environment.

Numerous intergenic regions showed expression. The majority were environment specific but most that were mutually expressed were structurally similar to protein-coding genes. They may well be un-annotated exons or genes. The environment specific regions were significantly shorter, overall, than coding sequences, and may represent polypeptides or non-coding RNA with regulatory or other functions.

Removing Radium-226 Contamination From Ion Exchange Resins Used In Drinking Water Treatment, James F. Mcmahon Iii.

Master's Theses and Capstones

Many groundwater sources used for drinking water in the United States contain naturally occurring gross alpha emitting radium-226 that exceeds the National Drinking Water Standards maximum contaminant level. The health risks associated with continuous and intermittent exposure to these low levels of naturally occurring radioactive material (NORM) over long periods of time can cause genetic damage which may lead to effects such as cancer. The EPA identifies ion exchange resins as a best available technology (BAT) in radium-226 removals. This determination has resulted in an increased need for knowledge about the characteristics of these resins. The ability of the resins …

The Teaching Of Elementary School Science In The Pre And Post No Child Left Behind Era: For Better Or Worse?, Jeffrey K. Perkins

Graduate Research Papers

A major problem confronting science education is the barriers elementary teachers face in teaching science. The reform efforts of the 1970's led initially to increased devotion of time in the area of science. The report "A Nation at Risk" published in the 1980's exposed the neglect of the American education system and helped lead to the establishment of standards and benchmarks for all school subjects.

The purpose of this paper was to examine the current state of elementary science in the No Child Left Behind [NCLB] school environment and compare this to the previous status of teaching science in the …

Novel Devices And Protocols Enabling Isolation And Enumeration Of Low Abundant Biological Cells From Complex Matrices, Andre Antonio Adams

LSU Doctoral Dissertations

The dimensions of microfluidic devices closely parallel those of biological cells; thusly, they are excellent platforms for the speciation, transport, manipulation, and analysis of cells. Electrokinetic transport of Escherichia coli and Saccharomyces cerevisiae was evaluated in microfluidic devices fabricated in pristine and UV-modified poly(methylmethacrylate) and polycarbonate. The magnitude and direction of transport of the cells was dictated by the buffer composition, conduit surface chemistry, and intrinsic cellular electrical properties. Baker’s yeast in all devices migrated toward the cathode, because of their smaller electrophoretic mobility compared to the electroosmotic flow of the polymer. E. coli cells suspended in 20 mM PBS …

The Viability Of Learning Journals As An Instructional Methodology For Adult Learners, Gale R. Mazur

Theses and Dissertations

This qualitative study used student and faculty focus groups to examine learning journals' effectiveness as an instructional methodology for adults enrolled in undergraduate and graduate Organizational Leadership (OL) degree programs. Learning journals are assigned to encourage reflection; however, concerns have arisen from student complaints that they constitute busywork. The study's purpose was to examine learning journals' viability by determining to what extent they deepened and broadened students' understanding of leadership, generated greater self-awareness, provided a leadership development tool, and encouraged the application of leadership knowledge. Students nearing degree completion as well as faculty teaching in the OL programs participated in …

Experimental And Computational Study Of The Detection And Stability Of Polymorphs Using Pxrd, Dsc And Solubility, David F. Wells

Open Access Dissertations

Reliable detection of polymorphs and mixed phase crystal systems is an important area of investigation in the development of pharmaceutical (small molecule) ingredients. This work deals specifically with small molecular entities as distinguishable from large or macromolecules, which also are used as active pharmaceutical ingredients. The first manuscript describes a digital band-pass filter for removal of white noise in Powder X-ray Diffraction. The filter reduces the noise by 21% for a real PXRD diffractogram and 40% for a synthetic PXRD diffractogram while maintaining the integrity of diffraction intensities and diffraction angle positions. The solid phase form of an active pharmaceutical …

Advances In Global Optimization, Rajeswar R. Gattupalli

Open Access Dissertations

Optimization is an active area of research and an important computational tool in many fields of science and engineering. While many effective global optimization algorithms have been developed over the past decades, there is still a need for improved robustness, reliability and efficiency. Examples where improvements in robustness, reliability and efficiency are needed include finding the global minimum of molecular modeling problems and finding all physically relevant solutions for mathematical models of chemical engineering applications. This dissertation describes two novel advanced global optimization tools--a multi-scale terrain/funneling methodology and logarithmic barrier-terrain method--that provide improved robustness, reliability and computational efficiency for solving …

Silane-Based Copolymers As Chromatographic Stationary Phases, Deidre Lynn Blackwell

Open Access Dissertations

In this work, a group of thermally stable polar-embedded polymer based stationary phases are presented. The silane-based copolymer is synthesized by radical polymerization to incorporate polar groups, through phenylmaleimides, and alkoxysilane groups. By way of the alkoxysilane groups, the copolymer can be attached on to silica particles or converted to polymer-silica composite particles using tetraethoxysilane (TEOS) as a sol-gel precursor. Through characterizations in this work, they proved to be stable in high temperatures (400°C) as well as effective in high water mobile phases. Phenyl moieties of the material provide increased and sometimes excessive retention of analytes with pi-systems occurred in …

Microstructure Studies In Synthetic And Bio-Colloids, Imaging And Applications, Ashish Kumar Jha

Open Access Dissertations

The mean size of CTAB/HDBS mixed surfactant vesicles confined into the three-dimensional voids generated by the random close packing (RCP) of polystyrene beads, shows a systematic decrease as the characteristic confinement length scale is reduced. The RCP of polystyrene beads of radius Rb = 1.5μm, 0.25μm and 0.1μm, creates voids of characteristic dimensions R ∼ 0.22 Rb = 3300Ã…, 550Ã… and 220Ã… respectively. These void length scales are comparable to or less than the radii of vesicles formed in the system under conditions of no confinement. A simple thermodynamic model was developed accounting for the balance between increased enthalpy when …

Fabrication, Characterization And Application Of The Novel Bionanomaterials, Lan Yao

Open Access Dissertations

This dissertation focuses on developing methods to synthesize novel bionanomaterials, studying their properties and exploring their potential applications. Fabricating semiconducting nanowires is a significant challenge in making nanoscale electronic devices. We propose to use self-assembling biomolecules as templates for the fabrication of nanowires. Here we demonstrate that quantum dots (QDs) could be conjugated to actin filaments, forming long semiconductor filaments. We constructed an optical system and developed the interactive software for fluorescence anisotropy imaging of single QDs and QD-nanowires. The fluorescence anisotropy studies revealed that QD transition dipoles are likely circular (elliptical) dipoles. The fluorescence anisotropy of a single QD …

Chemistry Of Antibiotics From Atlantic Actinomycete And Bacillus Bacteria, Aaron Martin Socha

Open Access Dissertations

The emergence of drug-resistant pathogens requires the use of innovative therapeutic agents. Hospital-acquired (nosocomial) infections represent major health and economic burdens for patients and health care professionals. In the United States over 1 million nosocomial infections are caused by drug-resistant bacteria anually, with associated expenditures ranging from $4 to $30 billion. Methicillin-resistant Staphylococcus aureus (MRSA) commonly shows reduced susceptibility to β-lactam, peptide, macrolide, aminoglycoside, tetracycline, and lincosamide classes of antibiotics. The emergence of vancomycin-resistant enterococci (VRE) is even more alarming since glycopeptide antibiotics were once considered the drugs of last resort. Moreover, community-acquired MRSA infections are spreading out of the …

Structural Bone Density Of Pacific Cod (Gadus Macrocephalus) And Halibut (Hippoglossus Stenolepis): Taphonomic And Archaeological Implications, Ross E. Smith

Dissertations and Theses

Describing prehistoric human subsistence strategies and mobility patterns using archaeofaunal assemblages requires archaeologists to differentiate the effects of human behavior from natural taphonomic processes. Previous studies demonstrate that differences in bone density both within and between taxa contribute to variation in element representation in archaeofaunal assemblages. Measurements of contemporary Pacific Cod (Gadus macrocephalus) and Pacific Halibut (Hippoglossus stenolepis) skeletal elements using Dual Energy Absorptiometry (DEXA) and hydrostatic weighing revealed differences in bone volume density between elements and taxa.

Density values were highest in Pacific cod and halibut jaw elements; the lowest bone volume densities were measured in Pacific cod and …

Coupling The Hydrodynamic And Water Quality Model Ce-Qual-W2 With A Multi-Trophic Fish Bio-Energetics Model For Lake Roosevelt, Washington, Michael Lee Mckillip

Dissertations and Theses

Grand Coulee Dam created Franklin D. Roosevelt Lake as part of the Columbia Basin Project. Located in northeastern Washington State, the Project provides economically important hydropower (19 billion kilowatt hours per year), irrigation (225,000 ha), flood control, and sport fishing ($5 to 20 million annually). A good system understanding aids in balancing these beneficial uses for the 230 km long reservoir. The reservoir's atypical 45-day mean residence time is much shorter than a typical lake, and much longer than for a riverine dam. The spring freshet requires drawdowns of 15 to 20 m for flood control—the driving characteristic of reservoir …

Reduced Acute Inflammatory Responses To Microgel Conformal Coatings, Amanda W. Bridges, Neetu Singh, Kellie L. Burns, Julia E. Babensee, L. Andrew Lyon, Andrés J. García

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Implantation of synthetic materials into the body elicits inflammatory host responses that limit medical device integration and biological performance. This inflammatory cascade involves protein adsorption, leukocyte recruitment and activation, cytokine release, and fibrous encapsulation of the implant. We present a coating strategy based on thin films of poly(N-isopropylacrylamide) hydrogel microparticles (i.e. microgels) cross-linked with poly(ethylene glycol) diacrylate. These particles were grafted onto a clinically relevant polymeric material to generate conformal coatings that significantly reduced in vitro fibrinogen adsorption and primary human monocyte/macrophage adhesion and spreading. These microgel coatings also reduced leukocyte adhesion and expression of pro-inflammatory cytokines (TNF-alpha, IL-1 beta, …

Dms Air/Sea Flux And Gas Transfer Coefficients From The North Atlantic Summertime Coccolithophore Bloom, Christa Marandino, Warren J. De Bruyn, Scott Miller, Eric S. Saltzman

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Dimethylsulfide (DMS) atmospheric and oceanic concentrations and eddy covariance air/sea fluxes were measured over the N. Atlantic Ocean during July 2007 from Iceland to Woods Hole, MA, USA. Seawater DMS levels north of 55 degrees N ranged from 3 to 17 nM, with variability related to the satellite-derived distributions of coccoliths and to a lesser extent, chlorophyll. For the most intense bloom region southwest of Iceland, DMS air/sea fluxes were as high as 300 mu mol m(-2) d(-1), larger than current model estimates. The observations imply that gas exchange coefficients in this region are significantly greater than those estimated using …

Transcendental Idealism, Transcendental Realism, And The Possibility Of Objective Reference, Eric Dane Walker

Graduate Student Theses, Dissertations, & Professional Papers

The goal of my thesis is to understand why Kant thinks that transcendental idealism can secure empirical realism, the idea that there really exists an objective world that we can come to know through experience. I maintain that, according to Kant, the possibility of coming to know objective reality depends upon the possibility of referring to objects, which itself, Kant thinks, can be explained by transcendental idealism. The transcendental idealist worldview is supposed by Kant to explain the possibility of referring to objects because it recognizes that objects must conform to cognition and not the other way around. Therefore, I …

Lessons To Learn From All Out Invasion: Life History Of Brown Trout (Salmo Trutta) In A Patagonian River, Sarah Louise O'Neal

Graduate Student Theses, Dissertations, & Professional Papers

Brown trout (Salmo trutta) are widely introduced throughout Patagonia, though their distribution and impact in the region remain poorly documented. Life history flexibility, and particularly partial migration play a major role in the ability of this species to adapt to Patagonian rivers. Consequently, this study explored habitat, distribution and life history of a partially migratory population of brown trout in the Rio Grande in Tierra del Fuego, Argentina. It described what is known of the history of the invasion. Physical, chemical, and biological habitat data were collected for comparison between sites supporting resident fish with those supporting anadromous fish. Additionally, …

Seasonal Nutrient Dynamics In A Small-Scale Constructed Wetland Treating Primary Effluent With Applications Of Effluent Reuse In Biomass Production, Paul Thomas Miller

Graduate Student Theses, Dissertations, & Professional Papers

Constructed wetlands have been investigated for use in the treatment of municipal wastewater. Species of nitrogen and phosphorus are the nutrients of focus and biochemical oxygen demand (BOD), total suspended solids (TSS) and fecal coliform are the pollutants. Prior work has focused on design concepts, plant effects on nutrient and pollutant treatment, and annualized treatment performance characteristics. This work builds upon published design concepts and wetland plant community and its function and investigates seasonal treatment performance and the kinetics of treatment performance for certain nutrients and pollutants during each season. Previous engineering based work has broadly suggested that first order …