Digital Commons Network^™

Gordie News, February 2008, West Chester University Of Pennsylvania

Gordon Natural Area History & Strategic Plan Documents

No abstract provided.

An Open Study To Assess The Safety And Efficacy Of Heprovac-B Vaccine 10 Mcg-Dose For Adults, Hasnain Ali Shah, Wasim Jafri

Section of Gastroenterology

Heprovac B is a novel recombinant vaccine. There are many vaccines available in Pakistani market but Heprovac B claims to be immunogenic even at 10 meg dose. Aim of the study is to determine whether using 10 meg of Heprovac B vaccine is safe and effective in producing sufficient immunity in Pakistani population. One hundred and twenty five subjects, who fulfilled the Inclusion criteria, were enrolled for the study. Heprovac B was administered in a three-dose regimen given at 0, 1 and 6 months and adverse events were recorded. Immunogenicity was tested by measuring hepatitis B surface antibody one month …

Arsenic As An Endocrine Disruptor: Arsenic Disrupts Retinoic Acid Receptor–And Thyroid Hormone Receptor–Mediated Gene Regulation And Thyroid Hormone–Mediated Amphibian Tail Metamorphosis, Jennifer C. Davey, Athena P. Nomikos, Manida Wungjiranirun, Jenna R. Sherman, Liam Ingram, Cavus Batki, Jean P. Lariviere, Joshua W. Hamilton

Dartmouth Scholarship

Background:

Chronic exposure to excess arsenic in drinking water has been strongly associated with increased risks of multiple cancers, diabetes, heart disease, and reproductive and developmental problems in humans. We previously demonstrated that As, a potent endocrine disruptor at low, environmentally relevant levels, alters steroid signaling at the level of receptor-mediated gene regulation for all five steroid receptors.

Objectives:

The goal of this study was to determine whether As can also disrupt gene regulation via the retinoic acid (RA) receptor (RAR) and/or the thyroid hormone (TH) receptor (TR) and whether these effects are similar to previously observed effects on steroid …

A Quick Glimpse At Public And Academic Libraries In Addis Ababa, Ethiopia, Marie Paiva

Against the Grain

No abstract provided.

Overwintering Site Selection By Short-Horned Lizards (Phrynosoma Hernandesi) In Northeastern Colorado, Tom Mathies, Daniel J. Martin

United States Department of Agriculture Wildlife Services: Staff Publications

Radio telemetry was used to track 16 adult Short-Horned Lizards (Phrynosoma hernandesi) to their individual overwintering sites on the Central Plains Experimental Range (CPER) in Weld County, Colorado. Above-ground habitat characteristics of overwintering sites and randomly selected points within the study area were assessed. All individuals entered overwintering between 29 August and 19 September with a mean estimated entrance date of 7 September. Arrival of the first subzero nighttime air temperatures occurred shortly thereafter on 16 September. No lizard left its normal area of use to overwinter, and there was no tendency to aggregate. Lizards did not necessarily …

Using Rare Books To Inspire Learning -- Part 1: Anthropology - Diaries, Gene Waddell

Against the Grain

No abstract provided.

Treatment Of Hyperlipoproteinemia With Low Density Lipoprotein Antibodies In Rats, Abuelgassim O. Abuelgassim

Saudi Medical Journal

OBJECTIVE: To examine whether the vaccination with low density lipoprotein (LDL) antibodies could have a protective effect on rats developed atherosclerosis through the action of atherogenic diet. METHODS: Four groups of rats (ranged 8 and 14) were treated for 8 weeks (13 January 2007 to 9 March 2007) at the animal house, Faculty of Pharmacy, King Saud University, Riyadh, Saudi Arabia, with normal control diet (NC), normal control diet+LDL-Ab (NC +I), atherogenic diet (AT), and atherogenic diet + LDL-Ab (AT+I). Lipid concentrations and other different parameters were measured in serum. RESULTS: The concentrations of total cholesterol in atherogenic rats treated …

Non-Enzymatic Glycation In Diabetic Complications, Fatma Hussain, Munir A. Sheikh, Mohammad Arif, Arooj Arshad, Amer Jamil

Saudi Medical Journal

No abstract provided.

Possible Predisposing Factors For Thrombotic Cerebrovascular Accidents In Sudanese Patients, Abdelgadir H. Elagib, Ammar E. Ahmed, Abbashar Hussein, Ahmed M. Musa, Eltahir A. Khalil, Ahmed M. El-Hassan

Saudi Medical Journal

No abstract provided.

Abeta42 Mutants With Different Aggregation Profiles Induce Distinct Pathologies In Drosophila., Koichi Iijima, Hsueh-Cheng Chiang, Stephen A Hearn, Inessa Hakker, Anthony Gatt, Christopher Shenton, Linda Granger, Amy Leung, Kanae Iijima-Ando, Yi Zhong

Department of Biochemistry and Molecular Biology Faculty Papers

Aggregation of the amyloid-beta-42 (Abeta42) peptide in the brain parenchyma is a pathological hallmark of Alzheimer's disease (AD), and the prevention of Abeta aggregation has been proposed as a therapeutic intervention in AD. However, recent reports indicate that Abeta can form several different prefibrillar and fibrillar aggregates and that each aggregate may confer different pathogenic effects, suggesting that manipulation of Abeta42 aggregation may not only quantitatively but also qualitatively modify brain pathology. Here, we compare the pathogenicity of human Abeta42 mutants with differing tendencies to aggregate. We examined the aggregation-prone, EOFAD-related Arctic mutation (Abeta42Arc) and an artificial mutation (Abeta42art) that …

Repression Of Proinflammatory Gene Expression By Lipid Extract Of Nostoc Commune Var Sphaeroides Kützing, A Blue-Green Alga, Via Inhibition Of Nuclear Factor-Κb In Raw 264.7 Macrophages, Young-Ki Park, Heather E. Rasmussen, Sarah J. Ehlers, Kara R. Blobaum, Fan Lu, Vicki L. Schlegel, Timothy P. Carr, Ji-Young Lee

Department of Food Science and Technology: Faculty Publications

We investigated whether lipid extract from a blue-green alga, N. commune, modulates proinflammatory gene expression in RAW 264.7 macrophages. The cells were incubated with N. commune lipid extract (0–100 μg/mL) and subsequently activated by LPS (100 ng/mL). Quantitative real-time PCR analysis showed that mRNA abundance of proinflammatory mediators, including TNF-α, COX-2, IL-1β, IL-6, and iNOS, was significantly reduced by N. commune lipid extract in a dose-dependent manner. Secretion of TNF-α and IL-1β into cell culture medium was also significantly decreased by N. commune lipid extract. Thin-layer chromatography-densitometry analysis showed that N. commune …

Rapid Preclinical Detection Of Sheeppox Virus By A Real-Time Pcr Assay, C. A. Balinsky, Gustavo A. Delhon, G. Smoliga, M. Prarat, R. A. French, S. J. Geary, S. J. Geary, D. L. Rock, L. L. Rodriguez

Nebraska Center for Virology: Faculty Publications

Sheeppox virus (SPPV) is a member of the Capripoxvirus (CaPV) genus of the Poxviridae family. Members of this genus, which also include goatpox and lumpy skin disease viruses, cause economically significant disease in sheep, goats, and cattle. A rapid diagnostic assay for CaPV would be useful for disease surveillance as well as for detection of CaPV in clinical samples and for outbreak management. Here we describe a fluorogenic probe hydrolysis (TaqMan) PCR assay designed for rapid detection of CaPV and tested on sheep experimentally infected with a virulent strain of SPPV. This assay can detect SPPV in buffy coats, nasal …

Introducing Point Mutations Into The Atgs Of The Putative Open Reading Frames Of The Hsv-1 Gene Encoding The Latency Associated Transcript (Lat) Reduces Its Anti-Apoptosis Activity, Dale Carpenter, Gail A. Henderson, Chinhui Hsiang, Nelson Osorio, Lbachir Benmohamed, Clinton J. Jones, S L. Wechsler

School of Veterinary and Biomedical Sciences: Faculty Publications

The herpes simplex virus type 1 (HSV-1) latency associated transcript (LAT) gene has anti-apoptosis activity that directly or indirectly enhances the virus’s reactivation phenotype in small animal models. The first 1.5 kb of the primary 8.3 kb LAT is sufficient and some or all of it is necessary for LAT’s anti-apoptosis in transient transfection assays and for LAT’s ability to enhance the reactivation phenotype. Based on LAT’s genomic sequence, the first 1.5 kb contains eight potential open reading frames (ORFs) defined as an ATG followed by an in frame termination codon. In this study, point mutations were introduced into the …

Herbivore-Mediated Ecological Costs Of Reproduction Shape The Life History Of An Iteroparous Plant, Tom E. X. Miller, Brigitte Tenhumberg, Svata M. Louda

School of Biological Sciences: Faculty Publications

Plant reproduction yields immediate fitness benefits but can be costly in terms of survival, growth, and future fecundity. Lifehistory theory posits that reproductive strategies are shaped by tradeoffs between current and future fitness that result from these direct costs of reproduction. Plant reproduction may also incur indirect ecological costs if it increases susceptibility to herbivores. Yet ecological costs of reproduction have received little empirical attention and remain poorly integrated into life-history theory. Here, we provide evidence for herbivore-mediated ecological costs of reproduction, and we develop theory to examine how these costs influence plant life-history strategies. Field experiments with an iteroparous …

Fetal And Neonatal Responses Following Maternal Exposure To Mobile Phones, Ahmed Y. Rezk, Khaled Abdulqawi, Randa M. Mustafa, Hesham Al-Inany

Saudi Medical Journal

OBJECTIVE: To study fetal and neonatal heart rate (HR) and cardiac output (COP), following acute maternal exposure to electromagnetic fields (EMF) emitted by mobile phones. METHODS: The present study was carried out at Benha University Hospital and El-Shorouq Hospital, Cairo, Egypt, from October 2003 to March 2004. Ninety women with uncomplicated pregnancies aged 18-33 years, and 30 full term healthy newborn infants were included. The pregnant mothers were exposed to EMF emitted by mobile telephones while on telephone-dialing mode for 10 minutes during pregnancy and after birth. The main outcome were measurements of fetal and neonatal HR and COP. RESULTS: …

Autologous Serum Is More Effective Than Fetal Bovine Serum On Proliferation Of Bone Marrow Derived Human Mesenchymal Stem Cells, Mustafa Yilmaz, Ercument Ovali, Elif Akdogan, Ahmet Durmus, Mehmet Sonmez, Tamer Dikmen, Serdar B. Omay

Saudi Medical Journal

No abstract provided.

Two Cyclocoelids From The Lesser Yellowlegs, Tringa Flavipes (Scolopacidae), From The Central Flyway Of North America, Including The Description Of Haematotrephus Selfi N. Sp. (Digenea: Cyclocoelidae), Norman O. Dronen, Scott Lyell Gardner, F. Agustin Jimenez-Ruiz

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Seven specimens of cyclocoelids (6 specimens representing Haematotrephus selfi n. sp. and 1 specimen representing a second unidentified species of Haematotrephus) collected by the late Dr. J. Teague Self, former professor, Department of Zoology, University of Oklahoma, Norman, Oklahoma, U.S.A., from the body cavities of 3 lesser yellowlegs, Tringa flavipes, (2 birds collected from Roger Mills County, Oklahoma on 23 and 29 August 1963, and 1 collected from Manitoba, Canada on 3 June 1964) and deposited in the Manter Laboratory of Parasitology, University of Nebraska, Lincoln, Nebraska are described. Haematotrephus selfi n. sp. can be distinguished from all …

Climate Change And The Endangered Species Act: Building Bridges To The No-Analog Future, J.B. Ruhl

Vanderbilt Law School Faculty Publications

This Article examines the challenges global climate change presents for the Endangered Species Act (ESA) and its primary administrative agency, the U.S. Fish and Wildlife Service (FWS). Climate change will reshuffle ecological systems in ways that will defy prediction using existing knowledge and models, posing threats to species through primary and secondary ecological effects and the effects of human adaptation to climate change. Even assuming global-wide regulation of greenhouse gas emissions eventually yields a more stable climate variation regime, it will differ from the recent historical regime and many species will not survive the transition regardless of human interventions using …

Feba2008, Robert Kelly

Robert Kelly Manuscripts

From February 2008 Robert Kelly Archive.

Febc2008, Robert Kelly

Robert Kelly Manuscripts

From February 2008 Robert Kelly Archive.

Race And Redemption: Racial And Ethnic Evolution In Rudolf Steiner's Anthroposophy, Peter Staudenmaier

History Faculty Research and Publications

With its origins in modern Theosophy, Rudolf Steiner’s Anthroposophy is built around a racial view of human nature arranged in a hierarchical framework. This article examines the details of the Anthroposophical theory of cosmic and individual redemption and draws out the characteristic assumptions about racial and ethnic difference that underlie it. Particular attention is given to textual sources unavailable in English, which reveal the specific features of Steiner’s account of “race evolution” and “soul evolution.” Placing Steiner’s worldview in its historical and ideological context, the article highlights the contours of racial thinking within a prominent alternative spiritual movement and delineates …

University Students’ Conceptualization And Interpretation Of Topographic Maps, Douglas Clark, Stephen Reynolds, Vivian Lemanowski, Thomas Stiles, Senay Yaşar-Purzer, Sian Proctor, Elizabeth B. Lewis, Charlotte Stromfors, James Corkins

Department of Teaching, Learning, and Teacher Education: Faculty Publications

This study investigates the strategies and assumptions that college students entering an introductory physical geology laboratory use to interpret topographic maps, and follows the progress of the students during the laboratory to analyze changes in those strategies and assumptions. To elicit students’ strategies and assumptions, we created and refined a topographic visualization test that was administered before and after instruction to 26 students during the first semester of the study and to 92 students during the second semester. To more deeply understand how students think about and conceptualize topographic maps, we focused on eight individual students who were interviewed about …

Volume Cxxv, Number 12, February 1, 2008, Lawrence University

The Lawrentian

No abstract provided.

Neural Correlates Of Auditory Processing, Learning And Memory Formation In Songbirds, Raphael Pinaud, Thomas A. Terleph, Ryan D. Wynne, Liisa A. Tremere

Biology Faculty Publications

Songbirds have emerged as powerful experimental models for the study of auditory processing of complex natural communication signals. Intact hearing is necessary for several behaviors in developing and adult animals including vocal learning, territorial defense, mate selection and individual recognition. These behaviors are thought to require the processing, discrimination and memorization of songs. Although much is known about the brain circuits that participate in sensorimotor (auditory-vocal) integration, especially the “songcontrol” system, less is known about the anatomical and functional organization of central auditory pathways. Here we discuss findings associated with a telencephalic auditory area known as the caudomedial nidopallium (NCM). …

The Murray State News, February 1, 2008, The Murray State News

Murray State University Collection

No abstract provided.

Transforming Growth Factor-Beta Enables Nfatc1 Expression During Osteoclastogenesis., Sw Fox, Ke Evans, Ac Lovibond

School of Biomedical Sciences

Osteoclastogenesis is dependent on distinct stimuli that prime and activate osteoclast differentiation. One cytokine needed to prime monocytes for osteoclastogenesis is TGF-beta, which enables and augments RANKL and TNF-alpha-induced osteoclast differentiation. However, the precise time-period during which this occurs and the molecular mechanism mediating this action are unknown. We report here TGF-beta prime monocytes for osteoclast formation within 24h by regulating expression of NFATc1, a key osteoclastic transcription factor. TGF-beta directly induces cytoplasmic NFATc1 expression within 24h, but is unable to stimulate NFATc1 nuclear translocation. Furthermore, RANKL-induced NFATc1 expression is dependent on the presence of TGF-beta during the early stages …

Development Of A Three Dimensional Prolapse Model To Simulate Physiological Haemodynamics In A Stented Coronary Artery, Jonathan Murphy, Fergal Boyle

Conference Papers

Coronary stent implantation can improve blood flow in an artery that has been narrowed by the build up of arterial plaque. However, the haemodynamic effect of stent placement is unclear and may influence arterial restenosis (re-blockage). The degree of tissue prolapse between stent struts may be an important factor in predicting the restenosis rate of a stent due to the haemodynamic influence of the protruding tissue. In this paper a mathematical model has been developed to numerically predict the tissue prolapse for an artery implanted with a coronary stent. The prolapse model has been applied to the Gianturco-Roubin II (GR-II) …

Digestion Of Sand-Laden Manure Slurry In An Upflow Anaerobic Solids Removal (Uasr) Digester, Khursheed Karim, Rebecca Hoffmann, M. (Muthanna) H. Al-Dahhan

Chemical and Biochemical Engineering Faculty Research & Creative Works

Studies on the Performance of a Laboratory Scale Up flow Anaerobic Solids Removal (UASR) Digester Were Carried Out using Sand-Laden Cow Manure Slurries Having Total Solids (TS) Concentration as 50 and 100 G/l. Hydraulic Retention Time (HRT) Was Maintained as 32.4 Days, Which Resulted in the Volatile Solids (VS) Loading Rates of 1 and 1.64 G/l D. the UASR System Was Designed to Remove Sand from the Manure Slurry, While Anaerobically Digesting Biodegradable Solids Inside a Single Reactor. to Enhance the Contact of Microorganisms and Substrate, the Liquor from the Top of the Digester Was Recirculated through the Bed of …

Silvopasture: Establishment & Management Principles For Pine Forests In The Southeastern United States

United States Department of Agriculture, Forest Service / University of Nebraska-Lincoln: Faculty Publications

Silvopasture is an agroforestry practice that integrates livestock, forage production, and forestry on the same land management unit. Silvopasture systems are deliberately designed and managed to produce a high-value timber product (such as sawtimber) in the long term while providing short-term annual economic benefit from a livestock component through the management of forage or an annual crop component.

Well-managed silvopasture systems may also:

• Improve overall economic performance of a farm enterprise through diversification and maintaining biodiversity

• Maintain or increase tree growth

• Improve cool-season grass production

• Allow warm-season grass production with careful canopy management

• Provide shade …

Probabilities Of Low Nighttime Temperatures During Stocking And Harvest Seasons For Inland Shrimp Culture, Bartholomew W. Green, Thomas W. Popham

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Litopenaeus vannamei is cultured in earthen ponds at southern US inland sites when water temperatures permit shrimp survival and growth. The probability of a minimum air temperature < = 14 C for one, three, or five consecutive days at one coastal and eight inland sites where L. vannamei is or could be grown in ponds is high (50%) from late March through late April at all sites except Arcadia, Florida, and Harlingen, Texas. Probabilities are 10% by early May to early June. In the autumn, the 10 and 50% probability levels are reached in early- to mid-September and by late September to mid-October, respectively. Arcadia, Florida, and Harlingen, Texas, have the longest periods with low probabilities and Pecos, Texas, …