Digital Commons Network^™

Disruption Of C-Jun Reduces Cellular Migration And Invasion Through Inhibition Of C-Src And Hyperactivation Of Rock Ii Kinase., Xuanmao Jiao, Sanjay Katiyar, Manran Liu, Susette C Mueller, Michael P. Lisanti, Anping Li, Timothy G Pestell, Kongming Wu, Xiaoming Ju, Zhiping Li, Erwin F Wagner, Tatsuo Takeya, Chenguang Wang, Richard G Pestell

Kimmel Cancer Center Faculty Papers

The spread of metastatic tumors to different organs is associated with poor prognosis. The metastatic process requires migration and cellular invasion. The protooncogene c-jun encodes the founding member of the activator protein-1 family and is required for cellular proliferation and DNA synthesis in response to oncogenic signals and plays an essential role in chemical carcinogenesis. The role of c-Jun in cellular invasion remains to be defined. Genetic deletion of c-Jun in transgenic mice is embryonic lethal; therefore, transgenic mice encoding a c-Jun gene flanked by LoxP sites (c-jun(f/f)) were used. c-jun gene deletion reduced c-Src expression, hyperactivated ROCK II signaling, …

Measuring Bite Force In Small Mammals With A Piezo-Resistive Sensor, Patricia W. Freeman, Cliff A. Lemen

University of Nebraska State Museum: Mammalogy Papers

We tested the use of piezo-resistive force sensors to measure bite force in small mammals. These force sensors are thin (less than 1 mm) and can be used to measure forces up to 4,500 N. A battery-operated unit, ideal for field research, can be built easily and inexpensively. We tested this sensor in the laboratory and in the field on a variety of small mammals. Although our results indicate that the sensor is somewhat less accurate (coefficient of variation = 4%) than a conventional load cell, the small size and ease of use of the piezo-resistive detector is highly desirable. …

Laws Of The 70'S: Badiou's Revolutionary Untimeliness, Emily Apter

Cardozo Law Review

No abstract provided.

Bad U . . . ?, Pierre Legrand

Cardozo Law Review

No abstract provided.

An Investigation Of Kavilorai: A Hero Stone Site In The Nilgiri Mountains Of South India, Jacob Landon Bach

Masters Theses

This study explores the hero stones of the Nilgiri Mountains of South India. This project has focused on the site of Kavilorai for developing a stylistic base to compare other sites of the region with. After analysis it was determined that Kavilorai contained four separate, but connected stylistic expressions carved on the hero stones. The findings when compared with other upper elevation sites corresponded to a high quality/low quality theme, often incorporating the ritual suicide sati. When comparing the stylistic representation of the carved figures to the Badaga Lingayat temple of Seminatum there surfaced strong thematic and stylistic connections. The …

New York Law School Magazine, Vol. 27, No. 2, New York Law School

New York Law School Magazine

Features:

Score! The Story behind Our Latest and Greatest Bar Pass Results

Learning from a Legend: Professor Donald Zeigler on the Art of Teaching

Going Global: Our Alumni Take On the World

Who Can Be Against Fairness? The Case Against The Arbitration Fairness Act, Peter B. Rutledge

Scholarly Works

In this brief essay, I hope to lay out the case against the Arbitration Fairness Act.3 Part I of this Article addresses the “findings” on which the act is premised. It explains how in several respects the current research on arbitration flatly contradicts the premises animating those findings (in other respects, the data is incomplete, so the “findings” at best are better described as “untested hypotheses” or “assumptions”). Part II of this Article explains why postdispute arbitration is not a viable alternative to our present system of enforceable predispute arbitration clauses.

Making Nuisance Ecological, J.B. Ruhl

Vanderbilt Law School Faculty Publications

Common law nuisance doctrine has the reputation of having provided much of the strength and content of environmental law prior to the rise of federal statutory regimes in the 1970s, but since then has taken a back seat to regulatory law with respect to the environment. In particular, whereas nuisance doctrine has been criticized - many say too harshly - as being inadequate for dealing with the demands of modern pollution control, it has never been considered as having much at all to do with management of ecological concerns. Yet nuisance law evolves with changed circumstances and new knowledge. This …

Mind, Causation And Chinese Mentality, J. Randall Groves

Comparative Civilizations Review

No abstract provided.

The Moving Landscape: Perspectives On Place, Emily Goughary

Independent Study Project (ISP) Collection

The discourses of place, identity, and modernity have been thoroughly nuanced in development literature, though perhaps not through the lens that I am proposing to view them. My aim in conducting research on identity of place and by what processes they might be constructed is to examine the cultural knowledge and perception by which places are rendered meaningful. An important aspect of this type of research includes observing what processes of place and of the world outside a place influence the construction of the perceptions of modernity or progress. The nature of this research demands that it be done on …

Aprb2008, Robert Kelly

Robert Kelly Manuscripts

From April 2008 Robert Kelly Archive.

Apre2008, Robert Kelly

Robert Kelly Manuscripts

From April 2008 Robert Kelly Archive.

Response To Cross And Hasker, David B. Burrell C.S.C

Faith and Philosophy: Journal of the Society of Christian Philosophers

No abstract provided.

Class Schedule - Spring 2008, Office Of Registrar

Semester Schedules and Information

No abstract provided.

This Is To Whom It May Concern: A Guantanamo Narrative, Marc Falkoff

DePaul Journal for Social Justice

No abstract provided.

Keynote Address At The 10th Annual Dr. Martin Luther King, Jr. Reflection And Commemoration At Depaul University College Of Law January 21, 2008: Seasons In The Sun: Reflections On Race And The Race For The Democratic Party Presidential Nomination, Anthony Paul Farley

DePaul Journal for Social Justice

No abstract provided.

Dialogue Magazine, Spring 2008

Dialogue, the magazine of the DePaul University College of Law

No abstract provided.

The Pharmaceutical Frontier: Extending Generic Possibilities To Biologic Therapies In The Biologics Price Competition And Innovation Act Of 2007, A. Taylor Corbitt

DePaul Journal of Art, Technology & Intellectual Property Law

No abstract provided.

Treg Depletion Inhibits Efficacy Of Cancer Immunotherapy: Implications For Clinical Trials., James Curtin, Marianela Candolfi, Tamer Fakhouri, Chunyan Liu, Anderson Alden, Matthew Edwards, Pedro Lowenstein, Maria Castro

Articles

BACKGROUND: Regulatory T lymphocytes (Treg) infiltrate human glioblastoma (GBM); are involved in tumor progression and correlate with tumor grade. Transient elimination of Tregs using CD25 depleting antibodies (PC61) has been found to mediate GBM regression in preclinical models of brain tumors. Clinical trials that combine Treg depletion with tumor vaccination are underway to determine whether transient Treg depletion can enhance anti-tumor immune responses and improve long term survival in cancer patients. FINDINGS: Using a syngeneic intracrabial glioblastoma (GBM) mouse model we show that systemic depletion of Tregs 15 days after tumor implantation using PC61 resulted in a decrease in Tregs …

Collective Memory And Blood Feud: The Case Of Mountainous Crete, Aris Tsantiropoulos

SOLON Law, Crime and History (previously SOLON Crimes and Misdemeanours: Deviance and the Law in Historical Perspective)

Drawing upon ethnographic data from mountainous central Crete, a feuding society up to the present moment, this article will focus on cases of retaliatory crimes where men avenge a relative who was killed before they were born. In these cases, what is interesting is that there do not seem to be any factors in the present to fuel the fire of a past animosity between the two kinship groups. Instead, these men seek revenge looking either for the murderer himself or for one of his male relatives in the places where they were forced to emigrate after the commitment of …

Wayne E. Sabbe Arkansas Soil Fertility Studies 2007, Nathan A. Slaton

Arkansas Agricultural Experiment Station Research Series

Rapid technological changes in crop management and production require that the research efforts also be presented in an expeditious manner. The contributions of soil fertility and fertilizers are major production factors in all Arkansas crops. The studies described within will allow producers to compare their practices with the university’s research efforts. Additionally, soil test data and fertilizer sales are presented to allow comparisons among years, crops, and other areas within Arkansas.

Borat And Anti-Semitism, William C. James

Journal of Religion & Film

Is the film Borat (2006) an instance of anti-Semitism? Only if understood superficially, though Sacha Baron Cohen's Jewishness does not exempt Borat from charges of anti-Semitism. Does the film expose anti-Semitism in others, or at least uncover their indifference? Yes, partly, but while risking that the exposé itself will be misinterpreted. More subtly, the film ridicules Jewish worries about anti-Semitism, a strategy that undercuts moral earnestness. Finally, Borat challenges, by ridiculing more "sophisticated” social attitudes, the very basis on which one decides about the nature and existence of anti-Semitism. In short, Borat unmasks anti-Semitism to denounce it; but, even more, …

Foucault, Discipline And The Self: Exploring Mary's Relationship With God In The Nativity Story, Amarnat Amarasingam

Journal of Religion & Film

The Nativity Story has been the most recent film depicting Mary, Joseph and the baby Jesus. The paper explores what films depicting biblical characters may reveal about the psychological experiences they undergo. For example, how does Mary benefit from the virgin conception? How does she use the pregnancy to transform herself? I employ Michel Foucault's ideas concerning disciplinary regimes and 'technologies of the self' to attempt to answer these questions. I argue that, in the film, the moment at which Mary is used to achieve God's purposes, she enters into a disciplinary relationship with God. She also uses her pregnancy …

Report From Sundance 2008: Religion In Independent Film, William L. Blizek, Michele M. Desmarais, Rubina Ramji

Journal of Religion & Film

This is the report from Sundance Film Festival 2008.

Volume Cxxv, Number 17, April 1, 2008, Lawrence University

The Lawrentian

No abstract provided.

Seeing Inside The Mountains: Cynthia Rylant's Appalachian Literature And The "Hillbilly" Stereotype, Karen Roggenkamp

Faculty Publications

If Ob, as a West Virginia native, possesses the ability to see The Mysteries where others see only primitivistic whittling or, more pejoratively, tacky wooden trash cluttering the yards of mountain families, then Rylant's Appalachian works likewise depict characters who possess an ability to see beyond external markers and predictable interpretations, and who seek an emotional and spiritual interiority based on family, love, and sense of place. Rylant's words in The Relatives Came, When I Was Young in the Mountains, and Missing May work to restore the integrity of Appalachia as a place of "interior" values, a setting that symbolizes …

The Horseshoe Crab Conundrum: Can We Harvest And Conserve?, Jennifer Mattei, Mark Beekey

Biology Faculty Publications

Horeshoe crabs "Limulus polyphemus" are remarkable ‘living fossils’ which have unique blood cells (amebocytes) that are used to test human vaccines for bacterial contamination. In the 1950’s, scientists at the Marine Biological Laboratory in Woods Hole, Massachusetts, not only discovered amebocytes but also found that they had special properties. If the amebocytes came into contact with bacteria, they would instantly coagulate around the bacteria and attack it. The Woods Hole scientists took this unique property of horseshoe crabs and developed a test for bacterial contamination using a horseshoe crab blood derivative called Limulus Amebocyte Lysate (LAL).

This article describes discusses …

2008 Imsaloquium, Student Investigation Showcase, Illinois Mathematics And Science Academy

IMSAloquium Event Booklets

"Marking its twentieth year, IMSA’s Student Inquiry and Research Program (SIR) is a powerful expression of the Academy’s mission, “to ignite and nurture creative ethical minds that advance the human condition.”

The Mass. Memories Road Show: Some Notes On Bridging And Bonding, Joanne M. Riley

Joseph P. Healey Library Publications

Four years ago, the Mass. Studies Project at UMass Boston launched a cultural heritage project that we dubbed the “Mass. Memories Road Show,” a real-world mashup of PBS’s Antiques Road Show (people bring their personal stuff to a local event for professional perusal) and the Library of Congress’ American Memory Project (digitize historic stuff and share it with the world). Our ambitious goal was – and still is! – to visit each of the 351 communities in Massachusetts, inviting residents to bring in photographs that reflect themselves and their families in that community. At the public “Road Show” events, we …

The Effect Of Dexmedetomidine On The Mini-Cog Score And High-Mobility Group Box 1 Levels In Elderly Patients With Postoperative Neurocognitive Disorders Undergoing Orthopedic Surgery, Joan M Mastrobattista, Mark A Klebanoff, J Christopher Carey, John C Hauth, Cora A Macpherson, J Ernest, Margaret Cotroneo, Kenneth J Leveno, Ronald Wapner, Michael Varner, Jay D Iams, Atef Moawad, Baha M Sibai, Menachem Miodovnik, Mitchell Dombrowski, Mary J O'Sullivan, J Peter Vandorsten, Oded Langer

Faculty, Staff and Student Publications

Our objective was to determine the effect of body mass index (BMI) on response to bacterial vaginosis (BV) treatment. A secondary analysis was conducted of two multicenter trials of therapy for BV and TRICHOMONAS VAGINALIS. Gravida were screened for BV between 8 and 22 weeks and randomized between 16 and 23 weeks to metronidazole or placebo. Of 1497 gravida with asymptomatic BV and preconceptional BMI, 738 were randomized to metronidazole; BMI was divided into categories: < 25, 25 to 29.9, and > or = 30. Rates of BV persistence at follow-up were compared using the Mantel-Haenszel chi square. Multiple logistic regression was used to evaluate the effect …