Digital Commons Network^™

Theme For English A, B And E: An Anthology Of Identity In Cape Town, South Africa, Noelle Elizabeth Rose

Honors Scholar Theses

This collection of poetry from grade 11 students in Cape Town, South Africa seeks to explore self-identity in South African high school students. In reading through their personal work, one can identify four ways in which these students define themselves: using self-promotion, or a display of personal strength; self-doubt, or moments of vulnerability; self-exploration, or the literary journey students take to define and explore their lives; and self-definition through social issues, or the examining of important social issues in South Africa and how they play into the lives of students. This anthology and literary analysis explores life-defining issues that are …

Mathematical Modeling Of Oral Cavity Mucositis, Jason White

Honors Scholar Theses

Oral Mucositis is a condition seen in post-treatment mouth cancer patients and is a condition of which the pathobiology is not entirely known. It is a condition that shares many common pathways with other alimentary tract injuries such as inflammatory bowel disease. Mathematical modeling of the system can help to identify gaps in the current knowledge base as well as assist in generating new hypotheses and predicting clinical outcomes of conditions. A detailed mathematical model would assist researchers in determining which drug targets are worthwhile investigating. Deterministic modeling and Virtual Cell&#; software were used to assign rate constants to each …

Potential Role Of Adenosine Signaling In Acetic Acid Activation Of Murine Sensory Neurons, Ryan Vaughan

Honors Scholar Theses

Chronic respiratory illnesses are a significant cause of morbidity and mortality, and acute changes in respiratory function often lead to hospitalization. Air pollution is known to exacerbate asthma, but the molecular mechanisms of this are poorly understood. The current studies were aimed at clarifying the roles of nerve subtypes and purinergic receptors in respiratory reflex responses following exposure to irritants. In C57Bl/6J female mice, inspired adenosine produced sensory irritation, shown to be mediated mostly by A-delta fibers. Secondly, the response to inhaled acetic acid was discovered to be dually influenced by C and A-delta fibers, as indicated by the observed …

Season Of Birth Effects In Autism Spectrum Disorders, Kastley Marvin

Honors Scholar Theses

One factor that is investigated as a possible clue to etiological factors in Autism Spectrum Disorders (ASD) is season of birth. Season of birth effects could be the result of temperature, toxins, dietary changes, viral infections, and cultural or social factors that change seasonally (Bolton, Pickles, Harrington, Macdonald, & Rutter, 1992). A number of studies have looked for season of birth effects in ASD with no conclusive results. The current study analyzed season of birth effects in a sample of 441 children diagnosed with ASD. Analysis was also repeated after excluding prematurely born children from the data. Level of functioning …

Effects Of Food Primes And Thought Suppression On Eating Habits, Laura A. Sharpe

Honors Scholar Theses

Food primes and thought suppression have been identified as factors influencing poor eating choices. Primes affect people non-consciously by activating thoughts of food. Suppression of food thoughts leads to a preoccupation with food that is often followed by a hyperaccessibility of food thoughts and increased binging. The current study paired these two processes to examine their interactional effects. We manipulated exposure to food primes and instructions to suppress thoughts of a tasty snack food (M&Ms) for 76 college-aged women. We hypothesized that participants both primed with food images and asked to suppress would consume the most M&Ms at the end …

Comparison Of Chronic Wound Care Products, S. Hester, Joseph A. Woelfel

School of Pharmacy Faculty Articles

No abstract provided.

Agricultural Transformation And Livelihood Struggles In South Africa's Western Cape, Michaela B. Palchick

Geography Honors Projects

Agricultural Transformation and Livelihood Struggles in South Africa’s Western Cape South Africa’s post-Apartheid land reform programs redistribute previously white-owned farmland to a small percentage of blacks, and provide these new farmers with agricultural extension services that promote large-scale agriculture. Due to the national legacy of racial oppression and an international pressure for neoliberal development policies, there is scant infrastructural support for small-scale agriculture. Despite the government’s vision, most black farmers produce for local consumption because competing internationally is unfavorable, especially since the removal of agricultural subsidies in 1994. The shortcomings of the agricultural transformation program are apparent in the village …

The Hebrew Prophets And Sodom And Gomorrah , Ralferd C. Freytag

Consensus

Genesis 19; Judges 19:16-27

Leaf Area Index Simulation In Soybean Grown Under Near-Optimal Conditions, T. D. Setiyono, Albert Weiss, James E. Specht, Kenneth G. Cassman, A. Dobermann

Department of Agronomy and Horticulture: Faculty Publications

Different approaches have been used to simulate leaf area index (LAI) in soybean (Glycine max L. Merr). Many of these approaches require genotype-specific calibration procedures. Studies modeling LAI dynamics under optimal growth conditions with yields close to the yield potential of soybean have remained scarce. A sink-driven approach was developed and evaluated for LAI simulation in soybean under near-optimal environments. The rate of change in expanding leaf area was simulated using the first derivative of a logistic function accounting for plant population density, air temperature, and water deficit. The rate of change in senescing leaf area was also simulated …

Artificial Neural Network Estimation Of Soil Erosion And Nutrient Concentrations In Runoff From Land Application Areas, Minyoung Kim, John E. Gilley

Department of Agricultural and Biological Systems Engineering: Faculty Publications

The transport of sediment and nutrients from land application areas is an environmental concern. New methods are needed for estimating soil and nutrient concentrations of runoff from cropland areas on which manure is applied. Artificial Neural Networks (ANNs) trained with a backpropagation (BP) algorithm were used to estimate soil erosion, dissolved P (DP) and NH₄–N concentrations of runoff from a land application site near Lincoln, Nebraska, USA. Simulation results from ANN-derived models showed that the amount of soil eroded is positively correlated with rainfall and runoff. In addition, concentrations of DP and NH₄–N in overland flow …

Cellular Arrays (Us Patent Application), Angela K. Pannier, Eric A. Ariazi, V. Craig Jordan, Lonnie D. Shea

Department of Agricultural and Biological Systems Engineering: Faculty Publications

The present invention relates to characterizing transcription within cells. In particular, the present invention provides transfected cell arrays (e.g., two-dimensional and/or three-dimensional arrays) and systems, kits and methods utilizing the same (e.g., for transcriptional activity characterization). Compositions and methods of the present invention find use in, among other things, research, drug discovery and clinical (e.g., diagnostic, preventative and therapeutic) applications.

Removed Cases And Uninvoked Jurisdictional Grounds, Jeannette Cox

North Carolina Law Review

No abstract provided.

United States Food Law Update: Food Safely Planning, Attribute Labeling, And The Irradiation Debate, Bryan Endres

Journal of Food Law & Policy

This article summarizes significant changes and developments in food law throughout the second half of 2007. The previous edition of the Food Law Update noted the recent increase in imported food and the resulting stress placed on food safety agencies and customs officials. Detailed inspections of every food shipment entering the United States would quickly exhaust limited agency resources and cripple efficient international trade of food products. On the other hand, after several well-publicized food scares and the ongoing threat of international contamination, the public increasingly demands high levels of physical surveillance. As a part of this ongoing discussion, this …

Law, Biology, And Property: A New Theory Of The Endowment Effect, Owen D. Jones, Sarah F. Brosnan

Vanderbilt Law School Faculty Publications

Recent work at the intersection of law and behavioral biology has suggested numerous contexts in which legal thinking could benefit by integrating knowledge from behavioral biology. In one of those contexts, behavioral biology may help to provide theoretical foundation for, and potentially increased predictive power concerning, various psychological traits relevant to law. This Article describes an experiment that explores that context.

The paradoxical psychological bias known as the endowment effect puzzles economists, skews market behavior, impedes efficient exchange of goods and rights, and thereby poses important problems for law. Although the effect is known to vary widely, there are at …

Building Preservation Plan Richmond Plantation Manor House Cordesville, South Carolina, Hillary Nicole King

All Theses

No abstract provided.

Physics-Based Shape Morphing And Packing For Layout Design, Hong Dong

All Dissertations

The packing problem, also named layout design, has found wide applications in the mechanical engineering field. In most cases, the shapes of the objects do not change during the packing process. However, in some applications such as vehicle layout design, shape morphing may be required for some specific components (such as water and fuel reservoirs). The challenge is to fit a component of sufficient size in the available space in a crowded environment (such as the vehicle under-hood) while optimizing the overall performance objectives of the vehicle and improving design efficiency. This work is focused on incorporating component shape design …

Study Of Electrospinning Of Property-Modulated Biomedical Microfibers, Scott Taylor

All Dissertations

Electrospinning technologies have been of great interest in recent years, due in large part to developments in the field of Bioengineering, including the preparation of novel polymers and advances in tissue engineering, specifically for therapeutic applications. The electrospinning process is, in general, a very benign process that allows the preparation, under mild conditions, of micro- and nano-scale fibers from fiberforming materials, as well as traditionally non-fiber forming materials. This process is of specific interest to the biomedical community because it affords an opportunity to create highly-tailored novel constructs with a multitude of possible uses. Some proposed uses for these materials …

Characterization Of Soluble Matrix From Molluscan Shell With An Emphasis On Two Major Phosphoproteins From The Eastern Oyster, Crassostrea Virginica, Mary Johnstone

All Dissertations

The soluble organic matrix (SM) extracted from the shell of the Eastern oyster, Crassostrea virginica was analyzed to identify the constituent proteins and their structures. Two acidic proteins with estimated molecular weights of 48 and 55 kD were isolated and determined to have highly related structures. Both proteins are comprised primarily of aspartate, serine, and glycine which represent nearly 90% of the total amino acids. Studies indicate that both proteins are phosphorylated and have estimated isoelectric points in the range of 3 to 5. Evidence suggests that poly-aspartate and poly-serine domains are present in the 48 kD protein. Amino terminal …

Understanding "Sports Hernia" (Athletic Pubalgia) - The Anatomic And Pathophysiologic Basis For Abdominal And Groin Pain In Athletes, William C. Meyers, Edward Yoo, Octavia Devon, Nikhil Jain, Marcia Horner, Cato Lauencin, Adam Zoga

Department of Radiology Faculty Papers

Recent publicity and some scientific reports suggest increasing success in treating an entity called “sports hernia” - more accurately named athletic pubalgia. The primary purpose of this article is to portray what we believe to be the key concept for understanding this wide variety of abdominal and groin injuries that afflict high performance athletes. These injuries have been plaguing athletes for a long time, and past treatments, based on concepts of occult hernia or simple strains, have generally failed. The former concepts do not take into account the likely mechanisms of injury or various patterns of pain that these athletes …

Law, Biology, And Property: A New Theory Of The Endowment Effect, Owen D. Jones, Sarah F. Brosnan

William & Mary Law Review

Recent work at the intersection of law and behavioral biology has suggested numerous contexts in which legal thinking could benefit by integrating knowledge from behavioral biology. In one of those contexts, behavioral biology may help to provide theoretical foundation for, and potentially increased predictive power concerning, various psychological traits relevant to law. This Article describes an experiment that explores that context. The paradoxical psychological bias known as the "endowment effect" puzzles economists, skews market behavior, impedes efficient exchange of goods and rights, and thereby poses important problems for law. Although the effect is known to vary widely, there are at …

The Art Of Making Assessment Anti-Venom: Injecting Assessment In Small Doses To Create A Faculty Culture Of Assessment, Philip I. Kramer

Office of Academic Review and Curricular Advancement Staff Publications

No abstract provided.

Giving The Terminally Ill Their Due (Process): A Case For Expanded Access To Experimental Drugs Through The Political Process, Linda K. Leibfarth

Vanderbilt Law Review

The stated purpose of the Food and Drug Administration ("FDA" or "Agency") is "to promote and protect the public health." In furtherance of this end, the FDA has created a regulatory framework to ensure that drugs marketed to the general public are both safe and effective. However, critics insist that the FDA's paternalistic drug approval process does little to achieve its goal. At the onset of the AIDS epidemic in the 1980s, criticism of the FDA intensified, as the FDA's lengthy and expensive drug approval process hindered terminally ill AIDS patients' access to potentially lifesaving treatment. Advocates for these patients …

The N-Terminal Domain Of The Y-Box Binding Protein Yb-1 Plays A Major Role In Cell Proliferation And Apoptosis, Payal Khandelwal

Theses and Dissertations (ETD)

Y-box binding protein, YB-1, is a member of the cold shock domain superfamily of proteins. It is involved in a plethora of cellular functions, including cell proliferation. The molecular mechanisms governing the involvement of YB-1 in cell proliferation are still unclear. Earlier studies done in chicken pre-B lymphocyte DT-40 cells in our laboratory have shown that a targeted disruption in one allele of chicken YB-1

(Chk-Yb-1b) gene at its N-terminal domain resulted in multiple abnormalities in the heterozygous mutants, including slower growth rate, abnormal cell morphology, increased cell size, increased genomic DNA content and significant changes in levels of cell …

Golgi Specificity And Development Of Autoreactive B Cells, Fazlullah Salar Khan Nawazi

Theses and Dissertations (ETD)

B cell receptors with certain heavy/light chain pairs predominate in the periphery of anti-DNA heavy chain transgenic mice while certain other B cell receptors are absent. We wanted to know why. To answer this, we re-constructed B cell receptors represented in the anti-DNA transgenic mice by cloning them as single chain variable fragments (scFv) to analyze their affinity to dsDNA. scFv representing receptors that were recovered from the spleens of transgenic mice had very little to no affinity to dsDNA. scFv representing receptors that were absent in the spleen had high affinity to dsDNA. We therefore concluded that receptors with …

Biochemical And Immunological Mechanisms Underlying Differential Interaction Of Superantigens With Host Immunogenetic Factors In Streptococcal Sepsis, Mohammed Nooh

Theses and Dissertations (ETD)

Group A streptococci (GAS) are serious human pathogens that can cause a wide array of diseases ranging from pharyngitis to streptococcal toxic shock (STSS), which is caused by excessive cytokines responses triggered by streptococcal superantigens (Strep SAgs). SAgs interact simultaneously with HLA class II molecules on antigen presenting cells (APC) and with the T cell receptor beta chain variable elements (TCR V) and cause excessive stimulation of both cell types and massive release of inflammatory mediators.

The Strep SAgs include the streptococcal pyrogenic exotoxins (Spes), which play a crucial role in the pathogenesis of severe invasive streptococcal diseases, including Strep …

Reproductive Biology Of The Coyote (Canis Latrans): Integration Of Behavior And Physiology, Debra Anne Carlson

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Wild Canis species possess a unique suite of reproductive traits including social monogamy, copulatory lock/tie, and biparental care. Females are seasonally monestrous and experience an obligatory pseudopregnancy after spontaneous ovulation. While these characteristics have been ascribed to coyotes, an integrated profile of behavior and physiology has not yet been described. In this study, temporal correlations between steroid hormone levels and socio-sexual mating behaviors were documented, as were changes in vaginal epithelium. Pseudopregnancy was compared to pregnancy by contrasting hormone (progesterone, estradiol, prolactin and relaxin) profiles of unmated females to patterns obtained in alternate years when they bred. Meanwhile, social interactions …

Pathophysiology Of Arbroviral Encephalitides In Laboratory Rodents, Aaron L. Olsen

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Western equine encephalitis virus (WEEV) is an arboviral pathogen naturally found in North America. The primary disease phenotype associated with WEEV infection in susceptible hosts is a relatively long prodromal period followed by viral encephalitis. By contrast, in the current work, experimental inoculation of WEEV into the peritoneum of Syrian golden hamsters produced rapid death within approximately 96 h. It was determined that direct virus killing of lymphoid cells leads to death in WEEV-infected Syrian golden hamsters, and that inflammatory cytokines have the potential to enhance virus-induced lymphoid cell destruction. It was further concluded that WEEV retains its ability to …

Application Of Quantitative Models Of Choice To Alcohol-Maintained Behavior, Corina Jimenez-Gomez

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Choice procedures and quantitative models of choice behavior have been used to assess the reinforcing efficacy of drugs. Few studies, however, have used quantitative models of choice for the study of behavior maintained by alcohol. In addition, no studies have assessed the usefulness of quantitative models of concurrent-chains performance for the study of drug-associated cues. The purpose of the present series of experiments was to test the generality of the matching law with alcohol as a reinforcer and extend the use of quantitative models of concurrent-chains performance to behavior maintained by alcohol and alcohol-associated cues. In the first experiment (Chapter …

Land Use And Development In The Mojave Desert Region Of San Bernardino County, California: The Impact Of Changing Demographic Trends, Pete Gomben

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

This research contributes to the field of land use planning by examining the effects of demographic trends--also known as demographic futures--on growth and development projections for seven communities in the Mojave Desert region of San Bernardino County, California. Demographic trends based on California Department of Finance projections and land development data supplied by the Southern California Association of Governments were obtained for each of the communities for the period between 1990 and 2001. By using a spatially explicit urban growth model, these trends and data were then used to allocate community-specific future growth for Adelanto, Apple Valley, Barstow, Hesperia, Twentynine …

Islam And The Environment, Erin Knoerl

Verbum

In lieu of an abstract, below is the essay's first paragraph.

"The world today is under attack by a slow and steady enemy. The Earth’s health is getting more complicated as we speak. Over a course of a few years the average temperature of the earth has increased a couple of degrees. This is turn has created a snowball effect. The increase in temperature is causing glaciers to melt, which in turn has led to the ice to break off, stranding polar bears and penguins in the middle of the ocean. With the glaciers melting the sea level is changing …