Digital Commons Network^™

Humanized Chimeric Receptors In The Therapy Of Multiple Sclerosis, Ioana Moisini

Theses and Dissertations (ETD)

The role of autoreactive, antigen-specific T-cells in the development of autoimmunity has long been documented. T-cells expressing chimeric receptors are specifically redirected against such cells and have been proven to suppress autoimmune encephalomyelitis, the murine model of multiple sclerosis. We here demonstrate the ability of humanized chimeric receptors to suppress experimental autoimmune encephalomyelitis (EAE) in a humanized mouse model by redirecting T lymphocytes against autoreactive T-cells. The receptors were synthesized by linking the 84-102 epitope of human myelin basic protein (MBP) to the extracellular and transmembrane domains of the beta chain of human major histocompatibility complex (MHC) class II molecule …

Cardiopulmonary Predicators Of Dysfunctional Ventilator Weaning Response After Coronary Artery Bypass Graft, Annapoorna Mary

Theses and Dissertations (ETD)

Although the majority of coronary artery bypass graft (CABG) surgery patients are extubated within 6 to 8 hours following surgery, 20% to 40% of patients remain intubated 12 hours after surgery due to dysfunctional ventilator weaning response (DVWR). DVWR associated with increased morbidity and mortality (30% to 43%) following CABG surgery. Finding significant antecedence to predict DVWR could help to identify and prevent the complications from DVWR after CABG surgery. Literature review revealed that there is an association between cardiopulmonary indicators (CPI) and DVWR after CABG surgery. Cardiopulmonary indicators are the selected hemodynamic parameters that have an association with DVWR. …

Space Tourism Activities: Emerging Challenges To Air And Space Law?, Stephan Hobe, Gérardine Meishan Goh, Julia Neumann

Journal of Space Law

No abstract provided.

Case Note. Corporate-Sovereign Symbiosis: Wilson V. Imagesat International, Shareholders’ Actions, And The Dualistic Nature Of State-Owned Corporations, Jason A. Crook

Journal of Space Law

No abstract provided.

Interpreting The Fourteenth Amendment: Two Don'ts And Three Dos, Garrett Epps

All Faculty Scholarship

A sophisticated reading of the legislative record of the framing of the Fourteenth Amendment can provide courts and scholars with some general interpretive principles to guide their application of the Amendment to current legal problems. The author argues that two common legal conceptions about the Amendment are, in fact, misconceptions. The first is that the Amendment was chiefly concerned with the immediate situation of freed slaves in the former slave states. Instead, he argues, the legislative record suggests that the framers were broadly concerned with the rights not only of freed slaves but also of foreign-born immigrants in the North …

Defending Truth: Legal And Psychological Aspects Of Holocaust Denial, Kenneth Lasson

All Faculty Scholarship

From the still-burning embers of the Holocaust we have come once again to learn the terrible truth, that the power of Evil still lurks among the nations of the world, and cannot be underestimated. Nor can the effect of the spoken and written word, which in modern times must be taken in tandem with the violence of terrorism. Part I describes the background and nature of Holocaust denial, tracing the Nazis' adoption of a plan for the A "Final Solution of the Jewish Problem" through the post-War Nuremberg Trials to the present day. Part II examines the tension between free …

Household Land Management And Biodiversity: Secondary Succession In A Forest-Agriculture Mosaic In Southern Mexico, Rinku Roy Chowdhury

Geography

This study evaluates anthropogenic and ecological dimensions of secondary forest succession in Mexico's southern Yucatán peninsular region, a hotspot of biodiversity and tropical deforestation. Secondary succession in particular constitutes an ecologically and economically important process, driven by and strongly influencing land management and local ecosystem structures and dynamics. As agents of local land management, smallholding farmers in communal, i.e., ejido lands affect rates of forest change, biodiversity, and sustainability within and beyond their land parcels. This research uses household survey's and land parcel mapping in two ejidos located along the buffer of the Calakmul Biosphere Reserve to analyze how household …

The Association Between Distance To Water Pipes And Water Bodies Positive For Anopheline Mosquitoes (Diptera: Culicidae) In The Urban Community Of Malindi, Kenya, Daniel E. Impoinvil, Joseph Keating, Rinku Roy Chowdhury, Robert Duncan, Gabriel Cardenas, Sajjad Ahmad, Charles M. Mbogo, John I. Githure, John C. Beier

Geography

The increasing risk of mosquito-borne diseases in African urban environments has been partly attributed to failed planning and resource underdevelopment. Though engineered systems may reduce mosquito proliferation, there are few studies describing this relationship. This study investigates how engineered systems such as roads and piped water systems affect the odds of anopheline immatures (i.e., larvae and pupae) occurring in water bodies located in Malindi, Kenya. Anopheles gambiae s.s. (Giles), An. arabiensis (Patton), and An. merus (Dointz) were identified in urban Malindi, with Anopheles gambiae s.s. being the predominant species identified. The Breslow-Day test was used to explore interactions among independent …

Templated Fabrication Of Large Area Subwavelength Antireflection Gratings On Silicon, Chih-Hung Sun, Wei-Lun Min, Nicholas C. Linn, Peng Jiang, Bin Jiang

Mathematics and Statistics Faculty Publications and Presentations

We report a cheap and scalable bottom-up technique for fabricating wafer-scale, subwavelength-structured antireflection coatings on single-crystalline silicon substrates. Spin-coated monolayer colloidal crystals are utilized as shadow masks to generate metallic nanohole arrays. Inverted pyramid arrays in silicon can then be templated against nanoholes by anisotropic wet etching. The resulting subwavelength gratings greatly suppress specular reflection at normal incidence. The reflection spectra for flat silicon and the templated gratings at long wavelengths agree well with the simulated results using a rigorous coupled wave analysis model. These subwavelength gratings are of great technological importance in crystalline silicon solar cells.

Can Collective Action And Capacity Building Reduce Vulnerability Among Settled Pastoralists?, D. Layne Coppock, Solomon Desta, Getachew Gebru, Seyoum Tezera

Environment and Society Faculty Publications

In 2001 PARIMA and her partners began to create collective-action groups among illiterate, settled pastoralists in southern Ethiopia. These groups—dominated by women—focused on savings-led microfinance, small business, and livestock marketing to increase incomes and diversify livelihoods. Fifty-nine groups with over 2,100 members were formed using intensive capacity- building methods. After six years we wanted to compare group members with their neighbors who never participated in the PARIMA program. We surveyed 180 individuals from groups and paired control (traditional) communities. Respondents were asked to assess the extent that they perceived positive, negative, or no change in their lives over the past …

Bus Transit Equity Among Demographic Groups Considering Monetary And Travel Time Costs, Leonel Medellin

Graduate Theses, Dissertations, and Problem Reports (ETD)

The generalized cost of a transit user depends mostly on time and money spent per trip. On the other hand, time and distance determine most of the transit agency's cost to provide service. These are important factors to consider in determining the equity performance of service provided to users of different demographic groups. The purpose of this study is to determine significant statistical differences in resources spent by bus users in two metropolitan areas. The study measures inequality among different socioeconomic groups of users in terms of travel time and money consumed per mile in using the service. Inequality is …

Control On The Safe Distance In Front Of The Vehicle Using Brake Fuzzy Controller, Hayder Sabah

Iraqi Journal of Computers, Communications, Control and Systems Engineering

In this paper, fuzzy brake controller is proposed. It is build by using the theory of fuzzy sets. The rules base of this controller are based on the previous knowledge and experiences in vehicle field. The working of controller reduces the vehicle velocity to achieve the safe distance in front between the vehicle and anther vehicle that traveling in front of it. So the controller prevents the slip in the tires during braking. The velocity error and distance error are used as inputs and brake force as control action output for the controller. The simulations of fuzzy controller with nonlinear …

Development Of Pc Based Multi-Channel Programmable Logic Analyzer, Sarmed Hassan, Ali A. Ati

Iraqi Journal of Computers, Communications, Control and Systems Engineering

This paper presents the design and practical implementation of a multi-channel PC based logic analyzer. The analyzer has16 input channels with memory depth of 4K snapshots/channel and capture rate of up to 5 MHz. The analyzer parameters such as internal or external trigger source, falling or rising edge capture clock, state or timing measuring mode, number of pre-trigger and post-trigger snapshots, are made to be programmable and could be changed manually. The analyzer prototype consists of hardware part represented by the development of the interface ISA card and the software part that inVolves the kernel mode driver and the GUI …

Learner-Centered Assignments In Computer Literacy, Martha E. Myers, Meg C. Murray, Mario Guimaraes, Debra B. Geist

Faculty Articles

Literacy is a concept that is understood to be the identifier of an educated populace. In today's world, literacy includes computer literacy, as well as language and quantitative literacy. This paper describes exercises developed to improve first year students' computer literacy through more learner-centered engagement. Exercises are designed to support learner-centered goals of independent and responsible learners, appropriate breadth and depth of content, teacher as facilitator, and assessment woven into learning. Exercise topics include purchase of a personal computer, basic logic via spreadsheets, an annotated bibliography built with electronic resources, and an integrated assignment customized by and for each student.

Investigation Of Radio Frequency Discharges And Langmuir Probe Diagnostic Methods In A Fast Flowing Electronegative Background Gas, Nathaniel P. Lockwood

Theses and Dissertations

Discharges in a flowing background gas are used to produce charged and excited species for numerous applications including etching semiconductors and pumping gas discharge lasers (Pinhero and others, 1998). The effect of a flowing background gas on the charged and excited neutral species generation by an RF discharge in a flow tube and the diagnostics of the resulting plasma with a Langmuir probe have been investigated for pressures between 0.001 to 1 Torr and flow velocities up to 1000 m/s. This investigation was performed using a fluid method coupled to a chemical kinetic model and a hybrid Particle-In-Cell/Monte Carlo Collision …

Volume 32, No. 3

The Weldon Times

A student-run newspaper published at the School of Law at Dalhousie University.

Editor in Chief: James Lea

Layout Editor: Mavis Mak

Editors: Jenn Morrison, Cindy Locke, Jessica Hogeveen

The Microgeometry Parameters Of Uncoated And Zinc-Coated Cold Rolled Steel Strips, J Bidulská, T Kvačkaj, V Bodák, R Bidulský

Journal of Metals, Materials and Minerals

The microgeometry of surface is arithmetically expressed by the arithmetical mean deviation of the profile, Ra and peak count, Pc. Roughening of working rolls was achieved by using the technology EDT (Electric Discharge Texturing) and SBT (Shot Blast Texturing). The paper shows the relationship between the basic microgeometry parameters and the adjustment technology of working rolls. Zinc-coated cold rolled steel strips, uncoated cold rolled steel strips and the Ra, Pc parameters were measured using the tangent profilometer "Hommel Tester T1000". Measurements of Ra and Pc showed the scatter for SBT and EDT rolls, respectively. EDT can provide a considerably greater …

Primary Analysis Of Effective Permeability Of The Flame In Burning Natural Gas, R Jaroslav, R Magdalena

Journal of Metals, Materials and Minerals

This paper presents a method of analysis of effective permeability of the flame in burning natural gas. In order to conduct a complex analysis, it is necessary to determine this parameter as a special case of the process of quasi-plasma nature for the purpose of investigating the options for application of suitable industrial methods applied in similar cases. We observed the synergy of solenoid parameters of the plasma part of the flame with ceramic materials without any special additional customization of the measurement device. The processed results of measurement demonstrate additional requirements necessary for measurement technology. The method was applied …

Top Salespeople Don't Sell: Managing Frame Incongruence Through Network Partitioning, Stuart R. Strolin

Student Scholarship

Buying decisions surrounding complex, transformational software are not made by individuals but instead by buying teams. Existing research on sales behavior and salesperson traits focuses on one-to-one selling and gives little insight into the training and selection required of a successful sales force. This paper describes the selling style and personal traits of twelve successful salespeople engaged in complex computer software sales to buying teams. What do successful salespeople do and what is it about him/her that distinguishes the most successful? Technology Frames of Reference and Actor Network Theory were used to interpret the methods used in successfully selling to …

What Are They Thinking About R&D? A Strategic Core Competence, Or An Operational Business Decision?, Beth Fitz Gibbon

Student Scholarship

Semi-structured interviews were conducted with nineteen senior North American business practitioners in multinational corporations to understand their experiences with strategic planning and resource allocation for R&D. In particular, we sought to elicit insight about where planning and allocation overlap, and how they are executed today, vs. five to ten years ago. Findings indicate the outsourcing of R&D is rapidly increasing. R&D is becoming an operational business function as opposed to an internal investment in key knowledge for future firm sustainability. R&D also appears to no longer be a major focus of the strategic planning effort at the highest management levels. …

Everything Old Is New Again: Lessons From Dodge V. Ford Motor Company, M. Todd Henderson

Coase-Sandor Institute for Law & Economics Research Paper Series

No abstract provided.

Openline Newsletter, December 2007, Civil Service Council

OpenLine Newsletter

A monthly newsletter for Civil Service employees, Volume XXXII, Number 6, December 2007.

An Update: Preparation And Credentialing Requirements Of Two-Year College Technical Instructors: A National Study, Susan J. Olson, Cathy M. Spidell

Journal of STEM Teacher Education

This study was conducted to see what changes have occurred in the preparation and credentialing of postsecondary technical faculty. The specific objectives of this study were: (a) to describe current credentialing requirements for two-year college technical instructors; (b) to describe program requirements for postsecondary technical teacher education programs; and (c) to compare changes that have occurred since prior studies. Since 1990 there has been a decline in the number of states that have credentialing requirements—down from 19 to 11 in 2006. The number of programs that prepare postsecondary technical faculty appears to be stable at a time of anticipated shortage …

Complete Issue

Journal of STEM Teacher Education

No abstract provided.

Breast Tomosynthesis With Amorphous Selenium Digital Flat Panel Detector, Bo Zhao

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

[to be added]

Critique Of A Homuncular Model Of Mind From The Neo-Vitalist Perspective, Peter Vere Warden

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

[to be added]

Organic/Inorganic Nanocomposite Materials By Electrospinning And Their Properties, Guan Wang

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

[to be added]

Studies Of Decoherence In Rf Squid Qubits, Douglas A. Bennett

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

[to be added]

The Role Of Dynamic Muscle Contractions On Bone Loss And Muscle Atrophy In A Functional Disuse Mouse Model, Adiba Mir Ali

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

[to be added]

Mimicking Marine-Based Natural Systems: A Study Of Sediment-Hydrate Interactions Under In Situ Conditions, Michael Waldram Eaton

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

[to be added]