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2007

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The Role Of The Fda In Innovation Policy, Rebecca S. Eisenberg Jan 2007

The Role Of The Fda In Innovation Policy, Rebecca S. Eisenberg

Michigan Telecommunications & Technology Law Review

This Article reexamines the role of FDA regulation in motivating investment in biopharmaceutical innovation. I begin by challenging the standard story that it is the patent system that makes drug development profitable, and drug regulation that makes it costly, by showing how patents add to costs and how drug regulation works in tandem with patents to protect profits. I then compare FDA-administered exclusive rights to patents as a means of fortifying drug development incentives, suggesting ways that FDA-administered rights might be preferable both from the perspective of policy makers and from the perspective of firms. In the remainder of the …


The Rollamo 2007, Missouri University Of Science And Technology Jan 2007

The Rollamo 2007, Missouri University Of Science And Technology

Yearbooks

No abstract provided.


Increasing Energy Efficiency Through Improvements In Ladle Materials And Practices, Kent D. Peaslee, Semen Naumovich Lekakh, Jeffrey D. Smith, Mangesh Vibhandik Jan 2007

Increasing Energy Efficiency Through Improvements In Ladle Materials And Practices, Kent D. Peaslee, Semen Naumovich Lekakh, Jeffrey D. Smith, Mangesh Vibhandik

Materials Science and Engineering Faculty Research & Creative Works

Steel foundry ladle practices play an important role in total energy efficiency of melting as well as influence casting quality. Extensive heat losses in the ladle could be associated with excessive superheating of the melt before tap which increases energy consumption, promotes oxidation of the melt and increases refractory consumption. A high cooling rate of the liquid metal in the ladle could also cause casting quality instability. The overall ladle heat balance and components of heat losses were analyzed using FLUENT and FACTSAGE software and validated with experimental data from both the UMR foundry and industrial foundries. The purpose of …


Enhanced Electronic Conductivity In Si-Substituted Calcium Aluminate, Julia E. Medvedeva, Thomas O. Mason, Kenneth R. Poeppelmeier, Mariana I. Bertoni, Arthur J. Freeman Jan 2007

Enhanced Electronic Conductivity In Si-Substituted Calcium Aluminate, Julia E. Medvedeva, Thomas O. Mason, Kenneth R. Poeppelmeier, Mariana I. Bertoni, Arthur J. Freeman

Physics Faculty Research & Creative Works

Improved conductivity has been achieved by controllable substitution of an ultraviolet electronic conductor. The transparent conducting oxide system, H-doped Ca12Al(14−x)SixO(33+x/2) with x=0−4, exhibits a conductivity strongly dependent on the substitution level. Four-point direct current conductivity increases with x from 0.15 to 0.61 S/cm at room temperature. The observed conductivity behavior is consistent with the predictions of our first principles density functional calculations for the Si-substituted system with x=0, 2, and 4. Furthermore, the Seebeck coefficient is composition dependent suggesting the existence of an activated mobility associated with small polaron conduction. ©2007 American Institute of Physics


Differential Double Capture Cross Sections In P+He Collisions, Michael Schulz, T. Vajnai, J. A. Brand Jan 2007

Differential Double Capture Cross Sections In P+He Collisions, Michael Schulz, T. Vajnai, J. A. Brand

Physics Faculty Research & Creative Works

We have measured differential double capture cross sections for 15 to 150 keV p+He collisions. We also analyzed differential double to single capture ratios, where we find pronounced peak structures. An explanation of these structures probably requires a quantum-mechanical description of elastic scattering between the projectile and the target nucleus. Strong final-state correlations have a large effect on the magnitude of the double capture cross sections


Opportunities For Undergraduate Research Experiences (Oure) Research Papers 2006-2007 Vol. I, Ryan Abington, Sunil Aggarwal, Emily Bahram-Ahi, Lia Raquel Otal Bartnicki, Navarre Bartnz, Matthew Beyer, Devin Boyle, Joshua Bunch, Adam Bunton, Joshua Cardenzana, Joshua Carey, Brandi Clark, Cary Cooper, Ryan Dusheke, Agatha Dwilewicz, Joshua Eads, Josiah Elliott, Justin Enderle, David Erdos, Tyler Fears, Nathaniel Goss Jan 2007

Opportunities For Undergraduate Research Experiences (Oure) Research Papers 2006-2007 Vol. I, Ryan Abington, Sunil Aggarwal, Emily Bahram-Ahi, Lia Raquel Otal Bartnicki, Navarre Bartnz, Matthew Beyer, Devin Boyle, Joshua Bunch, Adam Bunton, Joshua Cardenzana, Joshua Carey, Brandi Clark, Cary Cooper, Ryan Dusheke, Agatha Dwilewicz, Joshua Eads, Josiah Elliott, Justin Enderle, David Erdos, Tyler Fears, Nathaniel Goss

Opportunities for Undergraduate Research Experience Program (OURE)

No abstract provided.


The Use Of Thermoelectric Peltiers To Recapture Waste Heat, Navarre Bartz Jan 2007

The Use Of Thermoelectric Peltiers To Recapture Waste Heat, Navarre Bartz

Opportunities for Undergraduate Research Experience Program (OURE)

Peltier devices are a method of converting differences in temperature into electrical energy. Using data from a supplier of these devices, calculations were made to determine the efficiency of these devices in conjunction with a residential solar hybrid electric system. The initial calculations show efficiencies less than 2% with the temperature differences experienced during the springtime. While this efficiency doesn't sound stellar, taking into account the current efficiency of residential solar cells, this would be an appreciable addition to the power output of a residential solar system.


Durability Performance Of Polyurea Confined Concrete Cylinders, Matthew Beyer Jan 2007

Durability Performance Of Polyurea Confined Concrete Cylinders, Matthew Beyer

Opportunities for Undergraduate Research Experience Program (OURE)

No abstract provided.


Analysis Of Vertical Takeoff And Landing (Vtol) Unmanned Aerial Vehicles (Ua V) With Emphasis On Tilt Duct And Tilt Rotor Systems, Devin Boyle Jan 2007

Analysis Of Vertical Takeoff And Landing (Vtol) Unmanned Aerial Vehicles (Ua V) With Emphasis On Tilt Duct And Tilt Rotor Systems, Devin Boyle

Opportunities for Undergraduate Research Experience Program (OURE)

No abstract provided.


Identifying Trends In Underground Coal Mine Incidents Caused By Roof Falls, Cary Cooper Jan 2007

Identifying Trends In Underground Coal Mine Incidents Caused By Roof Falls, Cary Cooper

Opportunities for Undergraduate Research Experience Program (OURE)

Current technology and safety practices generally provide today's underground coal miner with a safe workplace in an unpredictable environment. However, incidents still occur and until the number of incidents resulting in injury or loss of life reaches zero, there will always be room for improving methods and technology used by the modern coal miner. This study analyzes underground coal mine incidents caused by roof falls. Information provided by the Mine Safety and Health Administration (MSHA) was analyzed for trends in factors that contribute to roof fall fatalities in underground coal mines. Identification of major contributing factors will allow for a …


Computational Study Of Laminar Separation Bubble Development Over Supersonic Airfoils At Subsonic Speeds, Josiah D. Elliott Jan 2007

Computational Study Of Laminar Separation Bubble Development Over Supersonic Airfoils At Subsonic Speeds, Josiah D. Elliott

Opportunities for Undergraduate Research Experience Program (OURE)

Laminar Separation Bubbles (LSBs) are regions of separated flow that start near the leading edge of an airfoil and reattach further down the airfoil surface. These regions of separation can appear at low angles of attack and can grow significantly as the angle of attack is increased heavily influencing the flow characteristics over the airfoil. Research on this topic is driven by the supersonic business jet industry which has a particular interest in this type of research due to performance requirements in both the subsonic and supersonic flight regimes. This manuscript is focused on the flow developments near the sharp …


Telangiectasia Detection In Dermoscopy Images, David Erdos Jan 2007

Telangiectasia Detection In Dermoscopy Images, David Erdos

Opportunities for Undergraduate Research Experience Program (OURE)

Melanoma lesions that exhibit irregular linear vessels can be misdiagnosed due to the fact that their clinical appearance can often closely resemble other skin conditions. Detection these irregular linear blood vessels, or telangiectasia could improve the accuracy of melanoma diagnosis. An algorithm that detects telangiectasia has been developed; it initially searches for color drops in an image in various directions and then uses various post processing techniques to improve the accuracy. The feasibility of using classifiers such as neural networks to further improve the accuracy has also been investigated.


Wireless Sensor Network Wildfire Detection System, Justin Enderle Jan 2007

Wireless Sensor Network Wildfire Detection System, Justin Enderle

Opportunities for Undergraduate Research Experience Program (OURE)

One of the current difficulties in battling the destructive and costly wildfires is in obtaining up to date, accurate information of the fire's current location and intensity. Current methods relying primarily on satellite technology are too slow and inaccurate, therefore a better method is needed to help lower the destruction caused by wildfires and reduce the resources needed to battle t hem. This research proposes distributing a large number of cheap sensors across an area encompassed by wildfire capable of organizing themselves into an ad-hoc wireless sensor network to monitor the fire's current intensity and location. The majority of work …


Growth Of Mc3t3-El Pre-Osteoblasts On Borate Containing Glasses & Growth Of Osteoblastic Cells On 13-93 Glass Scaffolds, Agatha Dwilewicz Jan 2007

Growth Of Mc3t3-El Pre-Osteoblasts On Borate Containing Glasses & Growth Of Osteoblastic Cells On 13-93 Glass Scaffolds, Agatha Dwilewicz

Opportunities for Undergraduate Research Experience Program (OURE)

Three borate-based glasses, compositions designated 1B, 2B, and 3B, with B203 levels of 15, 31, and 46 mole percent (Table 1), respectively, were tested for their effects on the growth of MC3T3-El mouse pre-osteoblastic cells under physiological fluid conditions. Silicate type 45S5 glass was used as a control for comparison. Independently, the biocompatibility of recently developed silicate-based porous 13-93 bioactive glass scaffolds was tested; Saos-2 human osteosarcoma cell line was used. Tests performed for the two studies included: contact assays of cell growth at the glass interface, chemical analysis of borate released into the culture medium, quantitative …


Days Without Immigrants: Analysis And Implications Of The Treatment Of Immigration Rallies Under The National Labor Relations Act, Michael C. Duff Jan 2007

Days Without Immigrants: Analysis And Implications Of The Treatment Of Immigration Rallies Under The National Labor Relations Act, Michael C. Duff

Denver Law Review

No abstract provided.


Non-Obviousness: The Fulcrum Of Combination Patent Validity, Matthew Faga Jan 2007

Non-Obviousness: The Fulcrum Of Combination Patent Validity, Matthew Faga

Denver Law Review

No abstract provided.


Three-Dimensional Structure Of Cdx (X= Se, Te) Nanocrystals By Total X-Ray Diffraction, S. K. Pradhan, Z. T. Deng, F. Tang, Y. Ren, Peter Moeck, V. Petkov Jan 2007

Three-Dimensional Structure Of Cdx (X= Se, Te) Nanocrystals By Total X-Ray Diffraction, S. K. Pradhan, Z. T. Deng, F. Tang, Y. Ren, Peter Moeck, V. Petkov

Physics Faculty Publications and Presentations

The three-dimensional structure of oleic acid-capped CdSe and thiol-capped CdTe nanocrystals used as quantum dots has been determined by total synchrotron radiationx-ray diffraction and atomic pair distribution function analysis. Both CdSe and CdTe are found to exhibit the zinc-blende-type atomic ordering. It is only slightly distorted in CdSe implying the presence of nanosize domains and very heavily distorted in CdTe due to the presence of distinct core-shell regions. The results well demonstrate the great potential of the experimental approach and thus encourage its wider application in quantum dot research.


Preparation Of Bioactive Glasses With Controllable Degradation Behavior And Their Bioactive Characterization, Aihua Yao, Deping Wang, Qiang Fu, M. N. Rahaman, Wen-Hai Huang Jan 2007

Preparation Of Bioactive Glasses With Controllable Degradation Behavior And Their Bioactive Characterization, Aihua Yao, Deping Wang, Qiang Fu, M. N. Rahaman, Wen-Hai Huang

Materials Science and Engineering Faculty Research & Creative Works

Bioactive glasses and ceramics have been widely investigated for bone repair because of their excel-lent bioactive characteristics. However, these biomaterials undergo incomplete conversion into a bone-like material, which severely limits their biomedical application. In this paper, borosilicate bioac-tive glasses were prepared by traditional melting process. The results showed that borosilicate glasses possessed high biocompatibility and bioactivity. In addition, when immersed in a 0.02 mol/L K2HPO4 solution, particles of a borate glass were fully converted to HA. The desirable conversion rate to HA may be achieved through the adjustment of the B2O3/SiO2 ratio. The results of XRD and FTIR analysis indicated …


Qualitative Data Analysis: Comparison Between Traditional And Computerized Text Analysis, Melissa A. Bright, Dawn O’Connor Jan 2007

Qualitative Data Analysis: Comparison Between Traditional And Computerized Text Analysis, Melissa A. Bright, Dawn O’Connor

All Volumes (2001-2008)

Most often quantitative data is used in the social sciences. Sometimes, however, researchers must use qualitative data for exploration. In a study on communication effectiveness we used both quantitative and qualitative data. After analyzing the quantitative data we used both a traditional text analysis and a computerized text analysis. Our aim in this paper is to discuss variance, or lack thereof, between outcomes utilizing traditional and computerized text analysis.


Laboratory Schools Annual Report, 2006-2007, Laboratory Schools, Illinois State University Jan 2007

Laboratory Schools Annual Report, 2006-2007, Laboratory Schools, Illinois State University

Annual Reports – Laboratory Schools

Illinois State University Laboratory Schools annual report


Methods To Improve Bond On Frp Wrapped Piles, Andy Schrader Jan 2007

Methods To Improve Bond On Frp Wrapped Piles, Andy Schrader

USF Tampa Graduate Theses and Dissertations

Fiber Reinforced Polymer (FRP) sheets can provide incredible structural strength while weighing only a fraction as much as steel. When applied to piles the FRP provides strengthening through both concrete confinement and tensile reinforcement. Mainly used in structural repair, its application is relatively simple in theory. However, many factors(some avoidable, some not) can interfere with the bond between FRP and concrete. When this bond is interrupted the strength of the repair becomes compromised.This thesis examines 2 new methods of improving FRP bond to concrete piles during the time the resin is curing. These methods are compared using 3 types of …


Vadose Zone Processes Affecting Water Fluctuations: Conceptualization And Modeling Considerations, Nirjhar Shah Jan 2007

Vadose Zone Processes Affecting Water Fluctuations: Conceptualization And Modeling Considerations, Nirjhar Shah

USF Tampa Graduate Theses and Dissertations

This dissertation focuses on a variety of vadose zone processes that impact water table fluctuations. The development of vadose zone process conceptualization has been limited due to both the lack of recognition of the importance of the vadose zone and the absence of suitable field data. Recent studies have, however, shown that vadose zone soil moisture dynamics, especially in shallow water table environments, can have a significant effect on processes such as infiltration, recharge to the water table, and evapotranspiration. This dissertation, hence, attempts to elucidate approaches for modeling vadose zone soil moisture dynamics. The ultimate objective is to predict …


Changes In Abundance And Distribution Of Humpback Whales, Megaptera Novaeangliae, In Hervey Bay Marine Park, Australia, Based On Aerial Surveys Conducted In 1992 And 2004, Lucã­A De La Paz Suzacq Jan 2007

Changes In Abundance And Distribution Of Humpback Whales, Megaptera Novaeangliae, In Hervey Bay Marine Park, Australia, Based On Aerial Surveys Conducted In 1992 And 2004, Lucã­A De La Paz Suzacq

USF Tampa Graduate Theses and Dissertations

Aerial surveys were conducted throughout Hervey Bay Marine Park between August and October 1992 and 2004 to determine changes in abundance and distribution of the Eastern Australia humpback whale population in this area. Due to concerns about possible effects of boat traffic on whale distributions associated with a growing whale watching industry, the number and location of vessels were also recorded during these surveys. Throughout the 1992 season, 17 flights were conducted and a total of 41.93 surveys hours were completed, recording 186 pods, and a total of 320 animals. In addition, 392 boats were spotted in the area. During …


Assessing The Reproducibility Of Skeletal Geochemistry Records In Atlantic Corals Using Montastraea Annularis Coral Heads From The Dry Tortugas, Florida, Kristine L. Stair Jan 2007

Assessing The Reproducibility Of Skeletal Geochemistry Records In Atlantic Corals Using Montastraea Annularis Coral Heads From The Dry Tortugas, Florida, Kristine L. Stair

USF Tampa Graduate Theses and Dissertations

Core samples were collected in September 1995 from live coral heads of Montastraea annularis at Bird Key reef in the Dry Tortugas, Florida (24 degrees 55 minutes N, 82 degrees 92 minutes W). Four 4 mm-thick coral slabs from two cores were continuously sampled at 12 samples per year (0.025 cm per sample for Core 31, 0.023 cm per sample for Core 35). Visual inspection of X-radiographs indicates an average skeletal extension rate of about 3 mm per year in Bird Key corals. The goal of this study was to perform a replication test in Montastraea annularis by using elemental …


Cellular Electrofusion Utilizing Corona Fields And Dc Pulse Technology, Joshua Stein Jan 2007

Cellular Electrofusion Utilizing Corona Fields And Dc Pulse Technology, Joshua Stein

USF Tampa Graduate Theses and Dissertations

Cell fusion is an important technique that is used in the field of medicine and biomedical research. For instance, fusion can be used to create hybridomas and novel types of secretory hybrid cells. It may also be used to engineer cultured insulin-secreting pancreatic B-cell lines for the treatment of diabetes. Historically, the applications listed above have been accomplished by a number of methodologies including dielectrophoresis, centrifugation, polyethylene glycol (PEG) and viral fusion proteins. However, these approaches often fail to produce the desired results due to poor cell viability, lack of 1:1 fusion, and use of non-physiological environments. It is proposed …


Technology And Older Faculty: A Descriptive Study Of Older Florida Community College Faculty, Christopher D. Van Der Kaay Jan 2007

Technology And Older Faculty: A Descriptive Study Of Older Florida Community College Faculty, Christopher D. Van Der Kaay

USF Tampa Graduate Theses and Dissertations

Institutions of higher learning across the United States are experiencing an aging faculty population. A significant proportion of college and university faculty are over 55, a growth expected to continue in future years. Parallel to this growth and change has been an expanding use of technology in higher education. Despite this trend and potential implications, few studies have provided in-depth insight into older faculty and technology. The study used a quantitative descriptive design to provide a comprehensive look at older community college faculty and various aspects of technology. Areas examined included older faculty's perceptions of technology, their attitudes toward institutional …


Experimental And Analytical Modeling Of The In Vivo And In Vitro Biomechanical Behavior Of The Human Lumbar Spine, Tov I. Vestgaarden Jan 2007

Experimental And Analytical Modeling Of The In Vivo And In Vitro Biomechanical Behavior Of The Human Lumbar Spine, Tov I. Vestgaarden

USF Tampa Graduate Theses and Dissertations

This dissertation has two major parts; Analytical and Experimental. The analytical section contains a study using Finite Element Analysis of dynamic instrumentation to demonstrate stress reduction in adjacent level discs. The experimental section contains biomechanical testing of facet fusion allograft technique and finally a comparison between In Vivo and In Vitro intradiscal pressures to determine forces acting on Lumbar spine segment L4-L5. A comprehensive study of available data, technology and literature was done. Conventional fusion instrumentation is believed to accelerate the degeneration of adjacent discs due to the increased stresses caused by motion discontinuity. A three dimensional finite element model …


Pneumatic Tool Hand-Arm Vibration And Posture Characterization Involving U.S. Navy Shipboard Personnel, Charles R. Wilhite Jan 2007

Pneumatic Tool Hand-Arm Vibration And Posture Characterization Involving U.S. Navy Shipboard Personnel, Charles R. Wilhite

USF Tampa Graduate Theses and Dissertations

The United States Navy incorporates many different occupations to ensure it achieves its overall mission. These occupations are extremely diversified and present a wide spectrum of occupational exposures. Many of these exposures have been well studied and documented. However, shipboard pneumatic tool hand-arm vibration, (HAV) and how it relates to different body postures is an area of occupational exposure that has received little attention. The chief objective of this study was to assess whether there is a difference in hand-arm vibration levels, while working on one of two surface orientations (e.g., horizontal and vertical) among distinctly different pneumatic tools while …


Graduate Students/Mothers Negotiating Academia And Family Life: Discourses, Experiences, And Alternatives, Shirlan A. Williams Jan 2007

Graduate Students/Mothers Negotiating Academia And Family Life: Discourses, Experiences, And Alternatives, Shirlan A. Williams

USF Tampa Graduate Theses and Dissertations

This study examines the experiences and perceptions of graduate students who are mothers. Based on discourse analysis, one-on-one interviews, and focus groups, this study argues that institutional discourses and practices place graduate students who are mothers in untenable and irreconcilable positions between "mom" and "student," between "family" and "the academy," between "self" and "success." These irreconcilable differences are created in discourse, enacted in institutional policies, and lived by the participants. The study offers action-based alternatives to the status quo policies of the university based on the self-described needs of these women. It reveals that support from all fronts--the home, the …


Modeling Considerations For Vadose Zone Soil Moisture Dynamics, Jing Zhang Jan 2007

Modeling Considerations For Vadose Zone Soil Moisture Dynamics, Jing Zhang

USF Tampa Graduate Theses and Dissertations

Reproducing moisture retention behavior of the upper and lower vadose zone in shallow water table settings provides unique challenges for integrated (combined surface and groundwater) hydrological models. Field studies indicate that moisture retention in shallow water table settings is highly variably affected by antecedent state and air entrapment. The theory and vertical behavior of a recently developed integrated surface and groundwater model (IHM) is examined through comparisons to collected field data in West-Central Florida. The objectives of this study were to (1) Identify important considerations and behavior of the vadose zone for reproducing runoff, ET and recharge in shallow water …