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Rescue The Americans With Disabilities Act From Restrictive Interpretations: Alcoholism As An Illustration, Judith J. Johnson

Journal Articles

The Supreme Court has narrowed the doorway into the protected class for the Americans with Disabilities Act of 1990 (ADA) in virtually every employment case. Taking their cue from the Supreme Court, the lower courts have been concerned principally with who is "disabled" and thus protected by the ADA. The answer today is not many people. The courts generally have been so hostile to ADA plaintiffs that it is difficult now to find a case in which the plaintiff was able to prove that he was disabled. Congress contemplated that some impairments would always be disabling. The Supreme Court, however, …

Human Health Risk Assessment For Aluminium, Aluminium Oxide, And Aluminium Hydroxide, Daniel Krewski, Robert A. Yokel, Evert Nieboer, David Borchelt, Joshua Cohen, Jean Harry, Sam Kacew, Joan Lindsay, Amal M. Mahfouz, Virginie Rondeau

Pharmaceutical Sciences Faculty Publications

A compendium is provided of aluminium compounds used in industrial settings, and as pharmaceuticals, food additives, cosmetics and as other household products. Most aluminium compounds are solids exhibiting high melting points. The solubility of aluminium salts is governed by pH, because the aluminium(III)-cation (Al³⁺) has a strong affinity for the hydroxide ion, which promotes precipitation. Like Mg²⁺ and Ca²⁺ ions, Al³⁺ in most situations seeks out complexing agents with oxygen-atom donor sites such as carboxylate and phosphate groups, including in biological systems. Aluminium oxides, hydroxides and oxyhydroxides occur in numerous crystallographic forms, which exhibit different …

Identification Of A Novel Polyomavirus From Patients With Acute Respiratory Tract Infections, Anne M. Gaynor, Michael D. Nissen, David M. Whiley, Ian M. Mackay, Stephen B. Lambert, Guang Wu, Daniel C. Brennan, Gregory A. Storch, Theo P. Sloots, David Wang

Open Access Publications

No abstract provided.

Control Of Inward Rectifier K Channel Activity By Lipid Tethering Of Cytoplasmic Domains, Decha Enkvetchakul, Iana Jeliazkova, Jaya Bhattacharyya, Colin G. Nichols

Open Access Publications

No abstract provided.

A Little Stress Is Good: Ifn-Γ, Demyelination, And Multiple Sclerosis, Jason R. Lees, Anne H. Cross

Open Access Publications

No abstract provided.

Nuclear Receptors Pparβ/Δ And Pparα Direct Distinct Metabolic Regulatory Programs In The Mouse Heart, Eileen M. Burkhart, Nandakumar Sambandam, Xianlin Han, Richard W. Gross, Michael Courtois, Carolyn M. Gierasch, Kooresh Shoghi, Michael J. Welch, Daniel P. Kelly

Open Access Publications

No abstract provided.

Emblica Officinalis And Its Enriched Tannoids Delay Streptozotocin-Induced Diabetic Cataract In Rats, P. Suryanarayana, Megha Saraswat, J. Mark Petrash, G. Bhanuprakash Reddy

Open Access Publications

No abstract provided.

Asthma Is Associated With Increased Mortality In Individuals With Sickle Cell Anemia, Jessica H. Boyd, Eric A. Macklin, Robert C. Strunk, Michael R. Debaun

Open Access Publications

No abstract provided.

Clustering Of Eating Disorder Symptoms In A General Population Female Twin Sample: A Latent Class Analysis, Alexis E. Duncan, Kathleen K. Bucholz, Rosalind J. Neuman, Arpana Agrawal, Pamela A F Madden, Andrew C. Heath

Open Access Publications

No abstract provided.

Coronavirus Replication Does Not Require The Autophagy Gene Atg5, Zijiang Zhao, Larissa B. Thackray, Brian C. Miller, Teresa M. Lynn, Michelle M. Becker, Eric Ward, Noboru N. Mizushima, Mark R. Denison, Herbert W. Virgin

Open Access Publications

No abstract provided.

Haplotype-Based Association Analysis Of The Mapt Locus In Late Onset Alzheimer's Disease, Odity Mukherjee, John Sk Kauwe, Kevin Mayo, John C. Morris, Alison M. Goate

Open Access Publications

No abstract provided.

Human T-Lymphotropic Virus Type-1 P30 Alters Cell Cycle G2 Regulation Of T Lymphocytes To Enhance Cell Survival, Antara Datta, Lee Silverman, Andrew J. Phipps, Hajime Hiraragi, Lee Ratner, Michael D. Lairmore

Open Access Publications

No abstract provided.

The Feasibility Of Oligogenic Combined Segregation And Linkage Analysis In Ceph Pedigrees, E Warwick Daw, Robert Yu

Open Access Publications

No abstract provided.

Intracellular Mediators Of Transforming Growth Factor Β Superfamily Signaling Localize To Endosomes In Chicken Embryo And Mouse Lenses In Vivo, Ramya Rajagopal, Shunsuke Ishii, David C. Beebe

Open Access Publications

No abstract provided.

The Bandit, A New Dna Transposon From A Hookworm— Possible Horizontal Genetic Transfer Between Host And Parasite, Thewarach Laha, Alex Loukas, Supatra Wattanasatitarpa, Jenjira Somprakhon, Nonglack Kewgrai, Paiboon Sithithaworn, Sasithorn Kaewkes, Makedonka Mitreva, Paul J. Brindley

Open Access Publications

No abstract provided.

Detection Of Intracellular Bacterial Communities In Human Urinary Tract Infection, David A. Rosen, Thomas M. Hooton, Walter E. Stamm, Peter A. Humphrey, Scott J. Hultgren

Open Access Publications

No abstract provided.

Electromagnetic Controlled Cortical Impact Device For Precise, Graded Experimental Traumatic Brain Injury, David L. Brody, Christine Mac Donald, Chad C. Kessens, Carla Yuede, Maia Parsadanian, Mike Spinner, Eddie Kim, Katherine E. Schwetye, David M. Holtzman, Philip V. Bayly

Open Access Publications

No abstract provided.

Use Of The Mitsunobu Reaction In The Synthesis Of Orthogonally Protected A,B-Diaminopropionic Acids, Fintan Kelleher, Keith Ó Proinsias

Articles

Orthogonally protected a,b-diaminopropionic acids have been synthesised in good yields by the reaction of N-trityl L-serine esters with N-substituted sulfonamides under Mitsunobu reaction conditions (DEAD, PPh₃, THF). The best isolated yields were obtained when N-Boc p-toluenesulfonamide was used as the nitrogen nucleophile precursor in the Mitsunobu reaction. Subsequently, the N-trityl group was efficiently replaced with the more stable allyloxycarbonyl (alloc) group.

Artemisinin-Resistant Mutants Of Toxoplasma Gondii Have Altered Calcium Homeostasis, Kisaburo Nagamune, Silvia N.J. Moreno, L. David Sibley

Open Access Publications

No abstract provided.

Adaptor Function Of Papf Depends On Donor Strand Exchange In P-Pilus Biogenesis Of Escherichia Coli, Yvonne M. Lee, Karen W. Dodson, Scott J. Hultgren

Open Access Publications

No abstract provided.

Common Genetic Risk Of Major Depression And Nicotine Dependence: The Contribution Of Antisocial Traits In A United States Veteran Male Twin Cohort, Qiang Fu, Andrew C. Heath, Kathleen K. Bucholz, Michael J. Lyons, Ming T. Tsuang, William R. True, Seth A. Eisen

Open Access Publications

No abstract provided.

Age At First Sexual Intercourse And Teenage Pregnancy In Australian Female Twins, Mary Waldron, Andrew C. Heath, Eric Turkheimer, Robert Emery, Kathleen K. Bucholz, Pamela A.F. Madden, Nicholas G. Martin

Open Access Publications

No abstract provided.

The Neuroendocrine Impact Of Chronic Stress On Cancer, Premal H. Thaker, Susan K. Lutgendorf, Anil K. Sood

Open Access Publications

No abstract provided.

Β2-Chimaerin In Cancer Signaling: Connecting Cell Adhesion And Map Kinase Activation, Stephen P. Bruinsma, Thomas J. Baranski

Open Access Publications

No abstract provided.

Direct Links: Using E-Mail To Connect Preservice Teachers, Experienced Teachers, And High School Students Within An Undergraduate Teacher Preparation Program, Alison Cook-Sather

Education Program Faculty Research and Scholarship

Much of preservice teacher education at the undergraduate level is based on indirect links between those preparing to teach and those who spend their days in schools. This article describes two kinds of direct links based in the culminating courses required for state certification to teach at the secondary level through an undergraduate teacher education program: one between preservice teachers and experienced teachers and one between preservice teachers and high school students. Consisting primarily of weekly e-mail exchanges, these dialogues constitute a unique forum for learning and teaching for all participants. The benefits participants identify-including the creation of a space …

Bearers Of Meaning, Dale Kinney

History of Art Faculty Research and Scholarship

No abstract provided.

Synecdoche And Surprise: Transdisciplinary Knowledge Production, Anne Dalke, Elizabeth Mccormack

Literatures in English Faculty Research and Scholarship

Using contemporary insights from feminist critical theory and the literary device of synecdoche, we argue that transdisciplinary knowledge is productive because it maximizes serendipity. We draw on student learning experiences in a course on “Gender and Science” to illustrate how the dichotomous frameworks and part-whole correspondences that are predominant in much disciplinary discourse must be dismantled for innovative intellectual work to take place. In such a process, disciplinary presumptions interrogate and unsettle one another to produce novel questions and answers.

The Road Also Taken: Lessons From Organic Agriculture For Market- And Risk-Based Regulation, Donald Thomas Hornstein

Faculty Publications

No abstract provided.

Regulating White Desire, Reginald Oh

Law Faculty Articles and Essays

This Article contends that segregationist justifications for miscegenation and segregation laws shows that those laws effectively imposed a legal duty on whites to adhere to cultural norms of endogamy. Dominant social groups enforce rules of endogamy⁠—the cultural practice of encouraging people to marry within their own social group⁠—to protect the dominant status of their individual members and of the social group in general. Thus, laws prohibiting interracial marriages regulated white desire in order to protect the dominant status of whites as a group. The Loving Court, therefore, ultimately was correct in declaring that miscegenation laws denied blacks equal protection.

Part …

What Now?: Evaluating Elearning Cpd Practice In Irish Third-Level Education, Roisin Donnelly, K. C. O'Rourke

Journal Articles

The internet has made it impossible for higher education institutions to ignore technology in fulfilling their strategic mission and respond to the expectations of a diverse student body. In the Republic of Ireland, as elsewhere, the use of online technologies has become an increasingly important challenge in academic staff development, and on the surface, eLearning has been moderately successful in the teaching and learning environment. However, given the rapid rate of change in both technology and the increasing diversity in academic staff and students, to describe accurately the nature of eLearning for academic staff development is near impossible. There has …