Digital Commons Network^™

Long-Term Consequences Of Methamphetamine Exposure In Young Adults Are Exacerbated In Glial Cell Line-Derived Neurotrophic Factor Heterozygous Mice, Heather A. Boger, Lawrence D. Middaugh, Kennerly S. Patrick, Sammanda Ramamoorthy, Emily D. Deheny, Haojie Zhu, Alejandra M. Pacchioni, Ann-Charlotte Granholm, Jacqueline F. Mcginty

MUSC Faculty Journal Articles

Methamphetamine abuse in young adults has long-term deleterious effects on brain function that are associated with damage to monoaminergic neurons. Administration of glial cell line-derived neurotrophic factor (GDNF) protects dopamine neurons from the toxic effects of methamphetamine in animal models. Therefore, we hypothesized that a partial GDNF gene deletion would increase the susceptibility of mice to methamphetamine neurotoxicity during young adulthood and possibly increase age-related deterioration of behavior and dopamine function. Two weeks after a methamphetamine binge (4 x 10 mg/kg, i.p., at 2 h intervals), GDNF +/- mice had a significantly greater reduction of tyrosine hydroxylase immunoreactivity in the …

Eng 3808-001, Ruth Hoberman

Fall 2007

No abstract provided.

Eng 1001g-037-055-064: Composition And Language, Dan Tessitore

Fall 2007

No abstract provided.

Eng 3010g-001: Literary Masterworks, John Kilgore

Fall 2007

No abstract provided.

Eng 3405-002: Children's Literature, Fern Kory

Fall 2007

No abstract provided.

The Murray Ledger And Times, August 15, 2007, The Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.

Eng 2003-001, John Martone

Fall 2007

No abstract provided.

Eng 1002g-012: Composition And Literature, Graham Lewis

Fall 2007

No abstract provided.

Isotype-Specific Antibody Responses Against Escherichia Coli O157:H7 Locus Of Enterocyte Effacement Proteins In Adult Beef Cattle Following Experimental Infection, G. Bretschneider, E. M. Berberov, Rodney A. Moxley

School of Veterinary and Biomedical Sciences: Faculty Publications

Escherichia coli O157:H7 is an important food-borne pathogen and cause of hemorrhagic colitis and hemolytic uremic syndrome in humans. Cattle are an important reservoir of E. coli O157:H7, in which the organism colonizes the intestinal tract and is shed in the feces. Vaccination of cattle has significant potential as a pre-harvest intervention strategy for E. coli O157:H7; however, basic information about the bovine immune responses to important bacterial colonization factors resulting from infection has not been reported. The serum and fecal IgG and IgA antibody responses of adult cattle to E. coli O157:H7 intimin, translocated intimin receptor (Tir), E. coli …

Small Spacecraft Mission Concepts To Achieve Lunar Science And Exploration Goals, Jennifer Heldmann, Tony Ricco, Carol Stoker, Tomas Svitek, Lori Fenton, Sylvia Cox, Lyn O’Leary, John Hines, Peter Klupar

Small Satellite Conference

NASA’s Vision for Space Exploration calls for a return to the Moon with both robotic spacecraft and human explorers in the coming decades. Both scientific and exploration-related goals can be achieved using a small spacecraft platform with relatively low cost and rapid development time. We report on mission concepts within five investigation themes and provide traceability to proposed instrumentation and measurement objectives. Specific themes addressed here include 1) Water, 2) Radiation Shielding, 3) Biologic Effects of the Lunar Environment, 4) Dust and Regolith Characterization, and 5) Enabling Lunar Astrophysics.

Celebrating 50 Years … Of Pioneering New Frontiers In Northeast Nebraska Public Field Day

Haskell Agricultural Laboratory (Northeast Research and Extension Center)

Contents:
Schedule of Events
Field Day Map
Exhibits and Activities
Brief History of the Haskell Ag Lab
A Very Special Thank You!
To Our Donors & Volunteers

Faculty And Professional Staff Conference, George C. Wright

President Emeritus George C. Wright Speeches

No abstract provided.

Nucleic Acids Encoding Sarcocystis Neurona Antigen And Uses Thereof, Daniel K. Howe

Veterinary Science Faculty Patents

The present invention provides novel isolated nucleic acids encoding antigenic proteins derived from Sarcocystis neurona, or unique fragments thereof. In particular, the invention provides novel isolated nucleic acids encoding membrane-associated polypeptides SnSAG2, SnSAG3, and SnSAG4. Also provided are purified antigenic polypeptide fragments encoded by the novel nucleic acid sequences set forth herein that encode for SnSAG2, SnSAG3, and SnSAG4. Also provided are isolated nucleic acids capable of selectively hybridizing with the nucleic acid from Sarcocystis neurona. The invention also provides vectors comprising the nucleic acids of the invention encoding an antigenic protein derived from Sarcocystis neurona or a …

Breaking Barriers Of Regeneration: Examining The Effectiveness Of Bird Perches In Facilitating Seed Dispersal In A Tropical Dry Forest, Muldrow Milton

Theses

This project examined the use of bird perches in facilitating seed dispersal to address the lack of seed dispersal and seed rain in degraded tropical forests. The goal of this project was to learn more about this practice in order to derive more realistic expectations of its effectiveness. After four months, significantly more seeds were dispersed into plots containing introduced perches as compared to subplots that lacked perches. Seed rain was dominated by Ficus citrifolia, a mid-level successional species, indicating that introduced artificial perches may influence the regeneration of more mature forests. Seeds recovered from seed traps represented species with …

The Function Of Mythology And Religion In Ancient Greek Society., Cara Leigh Sailors

Electronic Theses and Dissertations

The ancient Greeks are prime subjects of study for those wishing to understand the roles that religion and mythology play in a society and how the two interact with each other. This paper covers what I feel after my study of Greek mythology and religion are the eight functions of mythology: history, education, explanation - both of the natural world and the culture of each society, legality, genesis, what happens after death, and entertainment; as well as the two function of religion: civic and spiritual. In the first chapter, in order to show each of the mythological functions, I summarize …

Pleistocene Peccaries From Guy Wilson Cave, Sullivan County, Tennessee., April Season Nye

Electronic Theses and Dissertations

Descriptive and taphonomic analyses of undescribed Pleistocene Tayassuidae from Guy Wilson Cave within the East Tennessee State University and McClung Museum collections revealed a MNI of 16 Platygonus compressus and 2 Mylohyus from left femora and isolated teeth, respectively. Linkage between upper dentition and species identification is suggested by comparing Mylohyus fossilis to M. nasutus from other Pleistocene-aged sites. Long-bone NISP and age profiles show a predominance of Platygonus adults. Tayassuidae upper canines, likely Platygonus, suggest sexual dimorphism. Long bones were analyzed for carnivore damage and utilization revealing light utilization similar to that caused by modern wolves. Long bone …

Vitamin E (Tocotrienols) And Prostate Cancer: A Proteomics Approach., Christian Mbangha Muenyi

Electronic Theses and Dissertations

Proteomics is the large scale study of proteins in cells or organisms. The purpose of this study was to characterize the proteomic alterations occurring in a prostate cancer (LNCaP) cell line after treatment with delta-tocotrienol (a form of vitamin E not very prevalent from most dietary sources). We found that both gamma- and delta-tocotrienols induced time and concentration dependent growth inhibition and programmed cell dead (apoptosis) in LNCaP cells. Secondly, we used two-dimensional gel electrophoresis (2-DE) to characterize changes in protein expression levels associated with this treatment. Our results show that a specific set of proteins are regulated at both …

Confidence Intervals For Population Size In A Capture-Recapture Problem., Xiao Zhang

Electronic Theses and Dissertations

In a single capture-recapture problem, two new Wilson methods for interval estimation of population size are derived. Classical Chapman interval, Wilson and Wilson-cc intervals are examined and compared in terms of their expected interval width and exact coverage properties in two models. The new approach performs better than the Chapman in each model. Bayesian analysis also gives a different way to estimate population size.

The Effect Of Caffeine And Ethanol On Flatworm Regeneration., Erica Leighanne Collins

Electronic Theses and Dissertations

Flatworms, or planarian, have a high potential for regeneration and have been used as a model to investigate regeneration and stem cell biology for over a century. Chemicals, temperature, and seasonal factors can influence planarian regeneration. Caffeine and ethanol are two widely used drugs and their effect on flatworm regeneration was evaluated in this experiment. Non-toxic levels of caffeine, a stimulant, and ethanol, a depressant, were determined. The tails of the flatworms were removed and the regeneration stage was analyzed every 3 days for 15 days to see the effect of these drugs alone and in combination on regeneration. For …

Nicotine Sensitization In Β-Arrestin 2 Knockout Adolescent Mice., Jennifer A. Correll

Electronic Theses and Dissertations

ß arrestin-2 is a protein involved in signaling of D2 receptors and plays a mediating role in sensitization to psychostimulants and the opiate morphine. In this study, 3-4 week old BA-2 KO and wild type C57/B6 mice received nicotine tartarate (s.c, 0.5 mg/kg free base) for 7 or 14 consecutive days followed by a drug-free period. An acute nicotine challenge followed the drugfree period. Results indicated that the absence of ß-arrestin-2 reduced sensitization to nicotine in Experiment 1. BA-2 KOs eventually demonstrated sensitization in Experiment 2. However, absence of ß-arrestin-2 blocked expression of sensitization on the challenge. After the challenge, …

Antimicrobial Powders And Bio-Based Films, Byungjin Min

All Dissertations

Food safety can be improved by various antimicrobial applications through the effective inhibition of microorganisms for certain periods by controlled release. Antimicrobials in powders and films were studied to investigate their activities and properties. Nisin (Nisaplin®) (200, 400, 600, 800, and 1000 IU/ml) was adsorbed to silica and different corn starches and their antimicrobial activities against Listeria monocytogenes were evaluated by agar diffusion assay. Nisin-adsorbed silica (Celpure P-65) powder had the highest antimicrobial activity at 600 IU/ml and also confirmed that the highest amount of nisin was adsorbed onto silica at the same concentration. Efficacy of both unmodified corn starch …

The Effects Of Movement On Literacy., Kathy S. Luppe

Electronic Theses and Dissertations

The purpose of this study was to extend the knowledge of the relationship between movement and cognition by examining the impact of a sensory-motor program on the literacy skills of first grade learners from one elementary school in East Tennessee.

Literacy skills were evaluated using five subtests of the Dynamic Indicators of Basic Early Literacy Skills (DIBELS) assessment.

A 2 x 2 x 2 mixed factorial MANOVA was used to analyze group, gender, and test time effects on multiple dependent variables. The analysis yielded a statistically significant result (p < .05) in gains for the movement group and a …

Evaluation Of An Elementary School Wellness Concept In Rural East Tennessee., Audrey Lynn Taylor

Electronic Theses and Dissertations

Parents of elementary school children in the small, rural area of Unicoi County, TN were surveyed to determine their attitudes toward health, nutrition, and Unicoi County Schools' Wellness Policy. Elementary school classrooms were randomly chosen to receive surveys for the children's parents to return by mail. Data were compiled and analyzed using SPSS software. Over 99% of parents stated that nutrition education in schools was important, and 96% stated schools played an important role in their child's health. The assessment provided meaningful data and laid groundwork for future nutrition education programs. The research showed rural, lower-income parents are supportive of …

The Effects Of Nicotine Conditioned Place Preference In D2 Primed Adolescent Rats: Age-Related And Gender Effects., Yoko Emily Ogawa

Electronic Theses and Dissertations

This study investigated nicotine conditioned place preference (CPP) in two different ages of adolescence using a rodent model of schizophrenia. Both 2- and 3-chambered CPP apparatuses were used to test whether the CPP was due to an aversion to the white chamber. Animals were neontally treated with the dopamine D₂/D₃ agonist, quinpirole, or saline and raised to either early postweanling age (P 22) or adolescence (P 29). Rats were conditioned to prefer the white chamber using nicotine. Results showed that nicotine induced CPP and appeared to alleviate an increased stress response in D₂ primed animals, which …

Utilisation Of Dmc Experience And The Potential Usage Of Dmc Services To Provide Additional Support To A European Global Monitoring System Programme, M A Cutter, D Hodgson, P E Davies, A Baker, K Graham, S Mackin, M Vanotti, M N Sweeting, A Regan

Small Satellite Conference

Surrey Satellite Technology Ltd is reviewing the ability of small satellite platforms to add complementary capability to the presently defined Global Monitoring for Environment and Security (GMES) space segment, allowing the broadest possible set of user requirements to be met. A set of user-focused services has been compared with the instruments and measurement capabilities defined for the currently proposed Sentinel platforms. This comparison illustrated the challenges of using a few satellites, as in the current Sentinel scenario, carrying multiple instruments to serve the diverse needs of land, coastal, oceanic, emergency response and emergency management users.

Fast-Food Government And Physician-Assisted Death: The Role Of Direct Democracy In Federalism, K.K. Duvivier

Sturm College of Law: Faculty Scholarship

Modern patients often enter a twilight zone of suspended animation between living and dying that did not exist a generation ago. The majority of Americans believe these terminal patients should have the right to refuse life support and to receive pain relief, even to the point of hastening death. Yet laws addressing the situation are unclear, and physician advocates, like Dr. Kevorkian of Michigan, have faced sanctions and jail time when they responded to patient requests for help to die peacefully. In its 2006 Gonzales v. Oregon decision, the U.S. Supreme Court shifted the physician-assisted death dilemma to the state-side …

Faculty Handbook, 2007-2008, University Of Arkansas, Fayetteville

Faculty Handbook

No abstract provided.

Interview With Jan Serie, Professor Biology And Director Of The Center For Scholarship And Teaching, Jan Serie

Biology Department Oral Histories

No abstract provided.

August 11, 2007 (Pages 4417-4504), Pennsylvania Legislative Reference Bureau

Volume 37 (2007)

No abstract provided.

Clemson Commencement Program, August 2007, Clemson University

Clemson Commencement Programs

No abstract provided.