Digital Commons Network^™

Nmr Structures Of The Selenoproteins Sep15 And Selm Reveal Redox Activity Of A New Thioredoxin-Like Family, Andrew D. Ferguson, Vyacheslav Labunskyy, Dmitri E. Fomenko, Demet Arac, Yogarany Chelliah, Carlos A. Amexcua, Josep Rizo, Vadim N. Gladyshev, Johann Deisenhofer

Vadim Gladyshev Publications

Selenium has significant health benefits, including potent cancer prevention activity and roles in immune function and the male reproductive system. Selenium-containing proteins, which incorporate this essential micronutrient as selenocysteine, are proposed to mediate the positive effects of dietary selenium. Presented here are the solution NMR structures of the selenoprotein SelM and an ortholog of the selenoprotein Sep15. These data reveal that Sep15 and SelM are structural homologs that establish a new thioredoxinlike protein family. The location of the active-site redox motifs within the fold together with the observed localized conformational changes after thiol-disulfide exchange and measured redox potential indicate that …

A Topology-Constrained Distance Network Algorithm For Protein Structure Determination From Noesy Data, Yuanpeng Janet Huang, Roberto Tejero, Robert Powers, Gaetano T. Montelione

Robert Powers Publications

This article formulates the multidimensional nuclear Overhauser effect spectroscopy (NOESY) interpretation problem using graph theory and presents a novel, bottom-up, topology-constrained distance network analysis algorithm for NOESY cross peak interpretation using assigned resonances. AutoStructure is a software suite that implements this topology- constrained distance network analysis algorithm and iteratively generates structures using the three-dimensional (3D) protein structure calculation programs XPLOR/CNS or DYANA. The minimum input for AutoStructure includes the amino acid sequence, a list of resonance assignments, and lists of 2D, 3D, and/or 4D-NOESY cross peaks. AutoStructure can also analyze homodimeric proteins when X-filtered NOESY experiments are available. The quality …

Iwu French Horn And Tuba Ensembles To Perform, Kay Mitchell

News and Events (Discontinued Series)

No abstract provided.

Montana Kaimin, February 10, 2006, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

The Comet Assay To Determine The Mode Of Cell Death For The Ultrasonic Delivery Of Doxorubicin To Human Leukemia (Hl-60 Cells) From Pluronic P105 Micelles, Ghaleb A. Husseini, Kim L. O'Neill, William G. Pitt

Faculty Publications

This notes examines the mode of cell death of HL-60 cells exposed to 70 kHz and 1.3 W/cm2 in the presence of 1% Pluronic P105 and 1.67 μg/ml doxorubicin (Dox). The cells were ultrasonicated for 30, 60 and 120 minutes. They were then lysed, electrophorised, stained using propidium iodide, and their DNA profile captured using a fluorescent microscope. The gradual DNA damage observed and the comet tails captured after 1 and 2 hours of insonation suggest that the mode of cell killing is apoptosis.

Spartan Daily, February 9, 2006, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily (School of Journalism and Mass Communications)

Volume 126, Issue 9

Commonwealth Times 2006-02-09

Commonwealth Times, 1969-

No abstract provided.

February 9, 2006, James Madison University

The Breeze, 2000-2009

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

The Setonian, February 9, 2006, Seton Hall University

2006

No abstract provided.

R.I.T. News & Events - February 9, 2006, University News Services, Rochester Institute Of Technology

University Publications

Main features of this issue: Sentinel story documented in new Albert Paley book. Women's Council celebrates 50 years of service to RIT. RIT participates in WIRED project. RIT students help define 'Living Legacy' campaign. Students bring home scholastic gold at annual arts awards. News Briefs. Online business manages college application process. Country crooner to play Gordon Field House. Charles Arnold series to feature Jim Fiscus. The new COB idol. New student club takes the world seriously. Viewpoints. Why peer review?. RIT honors outstanding alums at awards ceremonies. A collaboration 'by design'. RIT music program thriving.A retirement party for old computers. …

Illinois State University Report, February 9, 2006, Illinois State University

Illinois State University Report (1966-2012)

Illinois State University bi-weekly employee newsletter.

The Pacifican February 9, 2006, University Of The Pacific

All Issues - Student Newspaper, The Pacifican, Pacific Weekly

No abstract provided.

The Missouri Miner, February 9, 2006

The Missouri Miner Newspaper

No abstract provided.

Senior From Pontotoc Crowned Miss University, Brooke Hatchett

University of Mississippi News

OXFORD, Miss. - A worthy performance onstage and a stellar interview behind the scenes earned University of Mississippi senior Tara Tutor the title of Miss University 2006 Wednesday evening at the Ford Center for Performing Arts.

Chanticleer | Vol 54, Issue 18, Jacksonville State University

Chanticleer

No abstract provided.

Daily Eastern News: February 09, 2006, Eastern Illinois University

February

No abstract provided.

Cbfbeta Is A Facultative Runx Partner In The Sea Urchin Embryo, Anthony J. Robertson, Carrie Dickey-Sims, Andrew Ransick, Dawn E. Rupp, John J. Mccarthy, James A. Coffman

Physiology Faculty Publications

BACKGROUND: Runx proteins are developmentally important metazoan transcription factors that form a heterodimeric complex with the non-homologous protein Core Binding Factor beta (CBFbeta). CBFbeta allosterically enhances Runx DNA binding but does not bind DNA itself. We report the initial characterization of SpCBFbeta, the heterodimeric partner of SpRunt-1 from the sea urchin Stronylocentrotus purpuratus.

RESULTS: SpCBFbeta is remarkably similar to its mammalian homologues, and like them it enhances the DNA binding of the Runt domain. SpCBFbeta is entirely of zygotic provenance and its expression is similar that of SpRunt-1, accumulating globally at late blastula stage then later localizing to endoderm and …

Adaptive Evolution Of Chloroplast Genome Structure Inferred Using A Parametric Bootstrap Approach, Liying Cui, Jim Leebens-Mack, Li-San Wang, Jijun Tang, Linda Rymarquis, David B. Stern, Claude W. Depamphilis

Faculty Publications

Background
Genome rearrangements influence gene order and configuration of gene clusters in all genomes. Most land plant chloroplast DNAs (cpDNAs) share a highly conserved gene content and with notable exceptions, a largely co-linear gene order. Conserved gene orders may reflect a slow intrinsic rate of neutral chromosomal rearrangements, or selective constraint. It is unknown to what extent observed changes in gene order are random or adaptive. We investigate the influence of natural selection on gene order in association with increased rate of chromosomal rearrangement. We use a novel parametric bootstrap approach to test if directional selection is responsible for the …

The Montclarion, February 09, 2006, The Montclarion

The Montclarion

Student Newspaper of Montclair State University

The Cowl - V. 70 - N/A - Feb 9, 2006

The Cowl

The Cowl - student newspaper of Providence College. Volume 70 - Number n/a - Valentine's Day Issue - February 9, 2006. 8 pages.

The Colby Echo (2006-02-09), Colby College

The Colby Echo

Published by the students of Colby College since 1877, The Colby Echo is the weekly, editorially independent student-run newspaper of Colby College in Waterville, Maine. Published monthly, 1877-1886; semi-monthly, 1886-1897; and weekly, during the academic year, 1898-present.

Jeffrey A. Frick Named Assistant Provost, Registrar At Illinois Wesleyan, Stew Salowitz

News and Events (Discontinued Series)

No abstract provided.

Montana Kaimin, February 9, 2006, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

Illinois Wesleyan University Announces Faculty Tenure, Advancement, Stew Salowitz

News and Events (Discontinued Series)

No abstract provided.

Evolution Of The Nanog Pseudogene Family In The Human And Chimpanzee Genomes, Daniel J. Fairbanks, Peter J. Maughan

Faculty Publications

The NANOG gene is expressed in mammalian embryonic stem cells where it maintains cellular pluripotency. An unusually large family of pseudogenes arose from it with one unprocessed and ten processed pseudogenes in the human genome. This article compares the NANOG gene and its pseudogenes in the human and chimpanzee genomes and derives an evolutionary history of this pseudogene family. Results: The NANOG gene and all pseudogenes except NANOGP8 are present at their expected orthologous chromosomal positions in the chimpanzee genome when compared to the human genome, indicating that their origins predate the human-chimpanzee divergence. Analysis of flanking DNA sequences demonstrates …

February 9, 2006, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Wagging The Contact Line: Transverse And Longitudinal Waves, S. Saritha, Partho Neogi

Chemical and Biochemical Engineering Faculty Research & Creative Works

Kinetics of wetting has been explored where the contact line not only sees a steady spreading but also has longitudinal or transverse oscillations imposed on it. The latter case is realized when spreading takes place over a rough surface. The effects of the imposed motion are small, which seem to be due to low spreading rates and small dynamic contact angles used in this study. However, a singularity is seen in viscous dissipation during the movement on the model rough surface, which is interpreted here as an instability that is similar to Haines' jumps and stick-slip phenomena, with possible entrainment …

Principled Parentage: Abandoning The Gender-Based Underpinnings Of Legal Parentage Analysis As Applied In The Context Of Gestational Surrogacy, Jennifer A. Kimball

ExpressO

While reproductive technology has provided new options for women who want children, our legal understanding of parentage is still informed by the traditional conception model of two parents: one male and one female. A parent who both is a biological parent and has developed a parent-child relationship with a genetic child ought to be considered a legal parent as well. This conclusion ought not to be vulnerable to attack based on the gender of the other parent; rather, each parent’s claims should be evaluated independently. When gender becomes irrelevant and we abandon the gender-based underpinnings of legal parentage analysis as …

Spartan Daily, February 8, 2006, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily (School of Journalism and Mass Communications)

Volume 126, Issue 8

The Cord Weekly (February 8, 2006)

The Cord

No abstract provided.