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Observer, Central Washington University

Student Newspaper

Student newspaper for Central Washington University for May 18, 2006

Disease Emergence And Resurgence: The Wildlife-Human Connection, Milton Friend

Other Publications in Wildlife Management

Humans have been affected by and have contributed to the eruption and spread of disease since antiquity. This connectivity is such that disease in the Americas was one of the five Seeds of Change addressed by the National Museum of Natural History’s commemoration of the Columbus Quincentenary. As for the other Seeds of Change, diseases “…sent ripples around the globe, affecting the people as well as the flora and fauna of both the New World and the Old.” During recent decades, these ripples have become waves that are likely to intensify, swelled by human population growth, civil strife, and other …

Ada News - 05/15/2006, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

May 15, 2006 Reporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Washington University Record, May 12, 2006

Washington University Record

No abstract provided.

An Investigation Into The Antifungal Activities Of N-Thiolated Beta- Lactams Against Selected Candida Species, Marci Culbreath

USF Tampa Graduate Theses and Dissertations

β-lactam antibiotics have long been a reliable course of treatment for bacterial infections. However, with recent increases in resistance and rising populations of immunocompromised patients new β-lactams have been synthesized and tested. The Turos laboratory has recently discovered novel β-lactams that have a mode of action distinct from penicillin and other β-lactam antibiotics as cell lysis is not observed. In the current investigations, these compounds are shown to also have antifungal properties. The rising incidence and prevalence of invasive fungal infections has become an increasing concern. The most common fungal pathogens involved in these infections are species in the genus …

Post-Miocene Expansion, Colonization, And Host Switching Drove Speciation Among Extant Nematodes Of The Archaic Genus Trichinella, D. S. Zarlenga, B. M. Rosenthal, G. Larosa, E. Pozio, Eric P. Hoberg

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Parasitic nematodes of the genus Trichinella cause significant food-borne illness and occupy a unique evolutionary position at the base of the phylum Nematoda, unlike the free-living nematode Caenorhabditis elegans. Although the forthcoming genome sequence of Trichinella spiralis can provide invaluable comparative information about nematode biology, a basic framework for understanding the history of the genus Trichinella is needed to maximize its utility. We therefore developed the first robust and comprehensive analysis of the phylogeny and biogeographic history of Trichinella using the variation in three genes (nuclear small-subunit rDNA, and second internal transcribed spacer, mitochondrial large-subunit rDNA, and cytochrome oxidase …

Conjugative Transfer Pathways Of High-Level Mupirocin Resistance And Conjugative Transfer Genes In Staphylococcus., Danielle Barnard

Electronic Theses and Dissertations

To combat widespread infections caused by Staphylococcus aureus, mupirocin was introduced at the Veterans Affairs Medical Center, Mountain Home, Tennessee. Soon after introduction, high-level mupirocin-resistance emerged. The rapid emergence was hypothesized to be due to conjugative transfer of the mupA resistance gene from S. epidermidis to S. aureus. Results have shown that transfer of high-level mupirocin-resistance from S. aureus donors commonly occurs. However, transfer from naturally-occurring S. epidermidis donors was not attainable. Staphylococcus epidermidis transconjugants, however, were capable of serving as donors. Further examination of non-transmissibility included PCR analysis of conjugative transfer genes (tra genes) in capable …

The Cost Of Mupirocin Resistance In Staphylococcus., Susan D. Reynolds

Electronic Theses and Dissertations

Control of antibiotic resistance in bacteria is based on the concept that resistance incurs a fitness cost in non-selective conditions. Fitness costs were assessed for low- and high-level mupirocin resistance in locally-derived Staphylococcus aureus and S. epidermidis. Costs of resistance were assessed in pure cultures by comparing growth curve characteristics and in mixed culture as the proportion of resistant cells surviving. Costs were not present in comparisons of growth rates among groups of naturally-occurring isolates from the different resistance categories. However, in S. aureus, growth rates within resistance categories differed by approximately 30 – 90%. Among near-isogenic pairs …

Washington University Record, May 5, 2006

Washington University Record

No abstract provided.

In Vitro Expression And Purification Of Class I Mhc Molecules, Loi Cheng

Honors Scholar Theses

The major histocompatibility complex (MHC) is a gene family responsible for many critical functions of the immune system in most vertebrates. The MHC consists of three classes differentiated by their structure and function, and MHC class I encodes antigen binding proteins as well as chaperone and accessory proteins such as tapasin. The purpose of this project is to reconstitute several human MHC class I molecules in their peptide-filled and peptide-deficient forms, and to purify these proteins for biochemical study. The expressed proteins include wild type and mutant variants of the fusion protein human leukocyte antigen HLA-B*0801-fos, and human beta-2-microglobulin (β2m). …

Evolutionary Epidemiology Of Endemic Gal¿Pagos Birds And Their Parasites, Noah Kerness Whiteman

Dissertations

In order to better understand parasite diversification, I went to the Gal¿pagos Islands to study the ecology and evolution of a model bird-parasite system, which included four phylogenetically independent ectoparasite lineages infecting the Gal¿pagos Hawk (Aves: Buteo galapagoensis). The parasites comprised two lice (Insecta: Phthiraptera: Amblycera, Ischnocera), a lousefly (Diptera: Hippoboscidae) and an avian skin mite (Acari: Epidermoptidae). Ultimately, my goal was to examine ectoparasite evolutionary epidemiology and disease susceptibility in relation to the host¿s ecological and colonization history. At the outset, I hypothesized that parasite natural history was key in influencing the coalescent process. Accordingly, I found differences …

Application Of Polymerase Chain Reaction To Screen Rodents From New Mexico, Texas, Bolivia, And Nicaragua For Leishmania And An Assessment Of The Specificity Of Primers, Robert Alan Miranda

Theses & Dissertations

Polymerase chain reaction was used to screen rodents from four regions for Leishmania and to screen isolates of L. enriettii and L. hertigi using L. mexicana complex primers and L. (Viannia) primers to examine the specificity of these primers. Twenty-five rodent specimens from Bolivia, 42 from Nicaragua, 84 from New Mexico, and 74 from Texas were tested for Leishmania. Two Oryzomys acritus and two Oryzomys nitidus from Bolivia and one Neotoma micropus from Texas tested positive for Leishmania and additionally tested positive with L. mexicana complex-specific primers. Isolates of L enriettii and L hertigi reacted with L mexicana complex …

Idcr: Infectious Diseases In Corrections Report, Vol. 9 No. 5, Infectious Diseases In Corrections

Infectious Diseases in Corrections Report (IDCR)

No abstract provided.

Penalized Splines For Longitudinal Data With An Application In Aids Studies, Hua Liang, Yuanhui Xiao

Journal of Modern Applied Statistical Methods

A penalized spline approximation is proposed in considering nonparametric regression for longitudinal data. Standard linear mixed-effects modeling can be applied for the estimation. It is relatively simple, efficiently computed, and robust to the smooth parameters selection, which are often encountered when local polynomial and smoothing spline techniques are used to analyze longitudinal data set. The method is extended to time-varying coefficient mixed-effects models. The proposed methods are applied to data from an AIDS clinical study. Biological interpretations and clinical implications are discussed. Simulation studies are done to illustrate the proposed methods.

Jmasm23: Cluster Analysis In Epidemiological Data (Matlab), Andrés M. Alonso

Journal of Modern Applied Statistical Methods

Matlab functions for testing the existence of time, space and time-space clusters of disease occurrences are presented. The classical scan test, the Ederer, Myers and Mantel’s test, the Ohno, Aoki and Aoki’s test, and the Knox’s test are considered.

Historical Lassa Fever Reports And 30-Year Clinical Update, Abe M. Macher, Martin S. Wolfe

Medicine Faculty Publications

Five cases of Lassa fever have been imported from West Africa to the United States since 1969. We report symptoms of the patient with the second imported case and the symptoms and long-term follow-up on the patient with the third case. Vertigo in this patient has persisted for 30 years.

What's Happening: May, 2006, Maine Medical Center

What's Happening

No abstract provided.

Pathogenocide : Infectious Disease And The Intent To Destroy, Kristy M. Layton

Yale Medicine Thesis Digital Library

No abstract provided.

Parasitism And A Shortage Of Refuges Jointly Mediate The Strength Of Density Dependence In A Reef Fish, Graham E. Forrester, Rachel J. Finley

Natural Resources Science Faculty Publications

Various predator-prey, host-pathogen, and competitive interactions can combine to cause density dependence in population growth. Despite this possibility, most empirical tests for density-dependent interactions have focused on single mechanisms. Here we tested the hypothesis that two mechanisms of density dependence, parasitism and a shortage of refuges, jointly influence the strength of density-dependent mortality. We used mark recapture analysis to estimate mortality of the host species, the bridled goby {Coryphopterus glaucofraenum). Sixty-three marked gobies were infected with a copepod gill parasite {Pharodes tortugensis), and 188 were uninfected. We used the spatial scale at which gobies were clustered naturally (~4 m^{2 …}

Faculty Senate Faculty Senate Operations Committee, 2006-2007, Vol 36, P 1543, Unm Faculty Senate

Faculty Senate Documents

No abstract provided.

Cotton Top Farm: A Natural Horsemanship Training Facility, Nicole Schiermeyer

Architecture Masters of Science Program: Theses

In order to meet the requirements of the masters of Architecture Terminal Project, I propose to design an equestrian training facility for Cotton Top Farms in St. Joseph, Missouri. The site is located in a rural area three miles outside of St. Joseph, Missouri, on a bluff which overlooks a flood plain. The area has been used for farming for over 150 years. The original farm was a dairy, 40 acres of which has been adapted into Cotton Top Farms, a small family horse farm. Cotton Top Farms was established in 1985 by the current owner functioning as a family …

Narrowed Tcr Repertoire And Viral Escape As A Consequence Of Heterologous Immunity, Markus Cornberg, Alex T. Chen, Lee A. Wilkinson, Michael A. Brehm, Sung-Kwon Kim, Claudia Calcagno, Dario Ghersi, Roberto Puzone, Franco Celada, Raymond M. Welsh, Liisa K. Selin

Interdisciplinary Informatics Faculty Publications

Why some virus-specific CD8 TCR repertoires are diverse and others restricted or “oligoclonal” has been unknown. We show here that oligoclonality and extreme clonal dominance can be a consequence ofTcell crossreactivity. Lymphocytic choriomeningitis virus (LCMV) and Pichinde virus (PV) encode NP205–212 epitopes that induce different but highly cross-reactive diverseTCRrepertoires. Homologous viral challenge ofimmune mice only slightly skewed the repertoire and enriched for predictable TCR motifs. However, heterologous viral challenge resulted in a narrow oligoclonal repertoire with dominant clones with unpredictableTCRsequences.This shift in clonal dominance varied with the private, i.e., unique, specificity of the host’s TCR repertoire and was simulated using …

Hypertension And Kidney Disease In Asia, Tazeen H. Jafar

Section of Nephrology

PURPOSE OF REVIEW: Communicable diseases were traditionally the major cause of public health concern in Asian countries, most of which were less developed. With industrialization and associated lifestyle changes during the past few decades, however, noncommunicable diseases similar to those that affect Western societies have emerged in Asian countries. The purpose of the review was to examine recent evidence about the burden and factors associated with hypertension and chronic kidney disease (CKD) in Asian countries.RECENT FINDINGS: Hypertension has become one of the leading causes of mortality in Asia. Although its prevalence continues to rise, it remains under-diagnosed and under-treated. CKD …

Knowledge, Attitude And Misconceptions Regarding Tuberculosis In Pakistani Patients, Javaid Ahmed Khan, Muhammad Irfan, Amna Zaki, Madiha Beg, Syed Fayyaz Hussain, Nadeem Rizvi

Section of Pulmonary & Critical Care

Objective:

To assess knowledge of patients with tuberculosis; about their disease and misconceptions regarding TB.

Methods:

A cross sectional study was conducted at Out-patient clinics of two teaching hospitals (private and public) in Karachi, Pakistan. A questionnaire was filled for the purpose.

Results:

A total of 170 patients were interviewed, 112 from private and 58 from a public sector hospital. Cough, fever, bloody sputum and chest pain were recognized as the common symptoms of TB. Eleven (7%) patients thought TB was not an infectious disease and 18 (10.6%) did not consider it a preventable disease. Contaminated food was considered the …

Ada News - 05/01/2006, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Impact Of Prisoner Sexual Violence: Challenges Of Implementing Public Law 108-79 The Prison Rape Elimination Act Of 2003, The;Symposium, Robert W. Dumond

Journal of Legislation

No abstract provided.

Staphylococcus Aureus Endocarditis Complicated By Bilateral Pneumothorax, Azza A. Alafify, Tarig S. Al-Khuwaitir, Bashir A. Wani, Samir M. Taifur

Saudi Medical Journal

Staphylococcus aureus is the most common cause of endocarditis in intravenous drug users. The organism gains access by intravenous injection or from the direct invasion of skin at injection sites. Known for its aggressiveness, the right sided endocarditis that ensues can lead to complications such as pulmonary abscesses and even death. We report the unusual case of an intravenous drug abuser, who following the occurrence of extensive pulmonary abscesses, developed bilateral pneumothoraces within a few days.

Anti-Hepatitis Delta Virus Seroprevalence And Risk Factors In Patients With Hepatitis B In Southeast Turkey, Mustafa K. Celen, Celal Ayaz, Salih Hosoglu, Mehmet F. Geyik, Mehmet Ulug

Saudi Medical Journal

OBJECTIVE: To obtain regional epidemiological data on hepatitis delta virus (HDV, a defective virus) infections, the incidence of anti-HDV positivity and the associated risk factors in asymptomatic hepatitis B virus surface antigen (HBsAg) carriers and in patients with chronic active hepatitis B. METHODS: The study took place at Dicle University Hospital (Diyarbakir, Southeast of Turkey) between January 2002 and July 2004. Anti-HDV screening was performed in asymptomatic hepatitis B carriers (N=889) and in patients with chronic active hepatitis B infection (N=120). We explored the association between anti-HDV positivity and asymptomatic hepatitis B carrier status, presence of active hepatitis B, age, …

“The Effectiveness Of Symbols” Revisited: Ayoreo Curing Songs, John Renshaw

Tipití: Journal of the Society for the Anthropology of Lowland South America

This essay considers a specific field of Amerindian knowledge, namely the sarode, or curing songs, of the Ayoreo of the Gran Chaco. It attempts to elucidate some of the taken-for-granted metaphysical assumptions that underlie Ayoreo epistemology. Following the approach taken in Joanna Overing’s introduction to Reason and Morality (1985), I will suggest that even these apparently simple, repetitive curing songs have to be understood as part of a broader corpus of “mythical” knowledge. They acquire their effectiveness or power, not through suggestion or metaphor but rather by harnessing the power of the “mythical” world of the jnani bajade, the …