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2006

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Efficacy And Safety Of The Six-Dose Regimen Of Artemether-Lumefantrine In Pediatrics With Uncomplicated Plasmodium Falciparum Malaria: A Pooled Analysis Of Individual Patient Data, M. Makanga, Zul Premji, C. Falade, J. Karbwang, E.A. Mueller, K. Andriano, P. Hunt, P.I. De Palacios Jan 2006

Efficacy And Safety Of The Six-Dose Regimen Of Artemether-Lumefantrine In Pediatrics With Uncomplicated Plasmodium Falciparum Malaria: A Pooled Analysis Of Individual Patient Data, M. Makanga, Zul Premji, C. Falade, J. Karbwang, E.A. Mueller, K. Andriano, P. Hunt, P.I. De Palacios

Pathology, East Africa

Patient data from eight clinical trials were pooled and analyzed to study the efficacy and safety of the six-dose versus four-dose regimen of artemether-lumefantrine (coartemether; Coartem) in children weighing 5-25 kg. A total of 544 patients with uncomplicated P. falciparum malaria (six-dose: 343; four-dose: 201), matched for demographic and baseline characteristics and individual coartemether doses were included in the analysis. Analysis of day 28 cure rate based on the intention-to-treat and evaluable populations yielded corrected cure rates for the six-dose regimen of 93% and 96% compared with 61% and 76%, respectively, for the four-dose regimen (P < 0.0001 for both comparisons). Similarly high cure rates were achieved with the six-dose regimen in non-immune infants weighing as little as 5 kg. The six- and four-dose regimens were equally well tolerated. The main finding of this analysis is that the six-dose regimen of coartemether is safe and more efficacious than the four-dose regimen in children. Copyright © 2006 by The American Society of Tropical Medicine and Hygiene.

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Voluntarism And Volunteering, Richard Holtzman Jan 2006

Voluntarism And Volunteering, Richard Holtzman

History and Social Sciences Faculty Journal Articles

To engage in voluntarism, as the term is commonly understood today, is to freely offer support in the service of others. Defining the concept in such general terms, however, ignores a number of important factors, such as the motives leading individuals to choose such action, the means by which the activity occurs, and the broader implications of voluntarism for society. This chapter looks at voluntarism from a historical perspective to demonstrate the numerous and sometimes conflicting ways the concept has been understood. Recognizing voluntarism as a social issue requires examining it in the variety of historical contexts and settings that …

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Protecting The Integrity Of Organic Food In The Face Of Genetic Engineering: The Case Of Roundup Ready Alfalfa, Kristina Joy Hubbard Jan 2006

Protecting The Integrity Of Organic Food In The Face Of Genetic Engineering: The Case Of Roundup Ready Alfalfa, Kristina Joy Hubbard

Graduate Student Theses, Dissertations, & Professional Papers

Genetically engineered (GE) seeds are central to the debates around agricultural biotechnology, and continue to be rapidly adopted across the globe. At the same time that GE crops increase in acreage, the organic market has become one of the fastest growing sectors of the American food industry. While biotechnology companies claim there is a successful “coexistence” of GE crop technologies and organic crops, many organic producers are already challenged by keeping unwanted GE traits out of their fields. Still, little attention has been given to the role of regulations in the face of organic contamination by genetically engineered material. This …

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World So Sweet| Essays On The Nature Of Food, Allison K. Clark Jan 2006

World So Sweet| Essays On The Nature Of Food, Allison K. Clark

Graduate Student Theses, Dissertations, & Professional Papers

No abstract provided.

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Gis Assessment Of Snow Leopard Potential Range And Protected Areas Throughout Inner Asia : And The Development Of An Internet Mapping Service For Snow Leopard Protection, Patricia Ann Williams Jan 2006

Gis Assessment Of Snow Leopard Potential Range And Protected Areas Throughout Inner Asia : And The Development Of An Internet Mapping Service For Snow Leopard Protection, Patricia Ann Williams

Graduate Student Theses, Dissertations, & Professional Papers

No abstract provided.

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Evaluation Of The Indicators And Standards Used For The Limits Of Acceptable Change Process In The Absaroka-Beartooth Wilderness, Sarah E. Wallace Jan 2006

Evaluation Of The Indicators And Standards Used For The Limits Of Acceptable Change Process In The Absaroka-Beartooth Wilderness, Sarah E. Wallace

Graduate Student Theses, Dissertations, & Professional Papers

No abstract provided.

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Impact Of Farm Size Tenancy And Landowner Gender On Riparian Buffer Width, Mark A. River Jan 2006

Impact Of Farm Size Tenancy And Landowner Gender On Riparian Buffer Width, Mark A. River

Graduate Student Theses, Dissertations, & Professional Papers

No abstract provided.

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Coming To The Table : Peacemaking And Truancy Rates In Schools With A High Enrollment Of American Indian Students, D. Abigail Rivenbark Jan 2006

Coming To The Table : Peacemaking And Truancy Rates In Schools With A High Enrollment Of American Indian Students, D. Abigail Rivenbark

Graduate Student Theses, Dissertations, & Professional Papers

No abstract provided.

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Intermittent Scheduled Feedings Increase Work Output During Wildfire Suppression, John S. Cuddy Jan 2006

Intermittent Scheduled Feedings Increase Work Output During Wildfire Suppression, John S. Cuddy

Graduate Student Theses, Dissertations, & Professional Papers

No abstract provided.

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The Worst Best Place: Stories Of Suicide In Montana, Brett Thomas-Dejohgh Jan 2006

The Worst Best Place: Stories Of Suicide In Montana, Brett Thomas-Dejohgh

Graduate Student Theses, Dissertations, & Professional Papers

This project tells the story of Montanans who, for now, have survived their battles against hopelessness in the state with the highest per capita suicide rate.

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Middle School Children Online: Comparing Parent Awareness And Supervision Of Students' Behaviors, Ann R. Minckler Jan 2006

Middle School Children Online: Comparing Parent Awareness And Supervision Of Students' Behaviors, Ann R. Minckler

Graduate Student Theses, Dissertations, & Professional Papers

No abstract provided.

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Damage Recognition And Repair Of Oxidized Guanine Lesions Induced By Chromium Exposure, M. Katie Hailer Jan 2006

Damage Recognition And Repair Of Oxidized Guanine Lesions Induced By Chromium Exposure, M. Katie Hailer

Graduate Student Theses, Dissertations, & Professional Papers

No abstract provided.

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Serotonin Transporter Inhibitor Ligands: Synthesis Of 2-(2-Alkyl-Piperazin-1-Yl)-6-Nitroquinoline Analogs As Potential Positron Emission Tomography Imaging Agents, Brian R. Kusche Jan 2006

Serotonin Transporter Inhibitor Ligands: Synthesis Of 2-(2-Alkyl-Piperazin-1-Yl)-6-Nitroquinoline Analogs As Potential Positron Emission Tomography Imaging Agents, Brian R. Kusche

Graduate Student Theses, Dissertations, & Professional Papers

No abstract provided.

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Factors Effecting Core Temperature And Hydration During Arduous Work, Julie A. Ham Jan 2006

Factors Effecting Core Temperature And Hydration During Arduous Work, Julie A. Ham

Graduate Student Theses, Dissertations, & Professional Papers

No abstract provided.

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Metabolic Gene Activation Following A Single Bout Of Extended-Duration Physical Activity And The Effects Of Carbohydrate Supplementation, Ana-Mishel Spiroski Jan 2006

Metabolic Gene Activation Following A Single Bout Of Extended-Duration Physical Activity And The Effects Of Carbohydrate Supplementation, Ana-Mishel Spiroski

Graduate Student Theses, Dissertations, & Professional Papers

No abstract provided.

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Constitutional Cases 2005: An Overview, Patrick J. Monahan, Christian Kurtz Jan 2006

Constitutional Cases 2005: An Overview, Patrick J. Monahan, Christian Kurtz

The Supreme Court Law Review: Osgoode’s Annual Constitutional Cases Conference

No abstract provided.

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And No More Shall We Shout: Noise By-Laws, Freedom Of Expression And A Montréal Sex Club, Richard Haigh, Batya Nadler Jan 2006

And No More Shall We Shout: Noise By-Laws, Freedom Of Expression And A Montréal Sex Club, Richard Haigh, Batya Nadler

The Supreme Court Law Review: Osgoode’s Annual Constitutional Cases Conference

No abstract provided.

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From The Mvr To Chaoulli V. Quebec: The Road Not Taken And The Future Of Section 7, Jamie Cameron Jan 2006

From The Mvr To Chaoulli V. Quebec: The Road Not Taken And The Future Of Section 7, Jamie Cameron

The Supreme Court Law Review: Osgoode’s Annual Constitutional Cases Conference

No abstract provided.

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Right Theory, Wrong Reasons: Dynamic Interpretation, The Charter And “Fundamental Laws”, Randal N. M. Graham Jan 2006

Right Theory, Wrong Reasons: Dynamic Interpretation, The Charter And “Fundamental Laws”, Randal N. M. Graham

The Supreme Court Law Review: Osgoode’s Annual Constitutional Cases Conference

No abstract provided.

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Paramountcy And Tobacco, Peter W. Hogg Jan 2006

Paramountcy And Tobacco, Peter W. Hogg

The Supreme Court Law Review: Osgoode’s Annual Constitutional Cases Conference

No abstract provided.

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Prophets Of Doom, Seers Of Fortune: 20 Years Of Expert Evidence Under The Oakes Test, Robert E. Charney, S. Zachary Green Jan 2006

Prophets Of Doom, Seers Of Fortune: 20 Years Of Expert Evidence Under The Oakes Test, Robert E. Charney, S. Zachary Green

The Supreme Court Law Review: Osgoode’s Annual Constitutional Cases Conference

No abstract provided.

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So What Is The Real Legacy Of Oakes?: Two Decades Of Proportionality Analysis Under The Canadian Charter’S Section 1, Sujit Choudhry Jan 2006

So What Is The Real Legacy Of Oakes?: Two Decades Of Proportionality Analysis Under The Canadian Charter’S Section 1, Sujit Choudhry

The Supreme Court Law Review: Osgoode’s Annual Constitutional Cases Conference

No abstract provided.

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Plasma Membrane Voltage Changes During Nanosecond Pulsed Electric Field Exposure, W. Frey, R. O. Price, P. F. Blackmore, R. P. Joshi, R. Nuccitelli, S. J. Beebe, K. H. Schoenbach, J. F. Kolb Jan 2006

Plasma Membrane Voltage Changes During Nanosecond Pulsed Electric Field Exposure, W. Frey, R. O. Price, P. F. Blackmore, R. P. Joshi, R. Nuccitelli, S. J. Beebe, K. H. Schoenbach, J. F. Kolb

Bioelectrics Publications

The change in the membrane potential of Jurkat cells in response to nanosecond pulsed electric fields was studied for pulses with a duration of 60 ns and maximum field strengths of similar to 100 kV/cm (100 V/cell diameter). Membranes of Jurkat cells were stained with a fast voltage-sensitive dye, ANNINE-6, which has a subnanosecond voltage response time. A temporal resolution of 5 ns was achieved by the excitation of this dye with a tunable laser pulse. The laser pulse was synchronized with the applied electric field to record images at times before, during, and after exposure. When exposing the Jurkat …

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Towards Community-Owned Forests: Landowner Perspectives On The Blackfoot Community Conservation Area, Alison L. Duvall Jan 2006

Towards Community-Owned Forests: Landowner Perspectives On The Blackfoot Community Conservation Area, Alison L. Duvall

Graduate Student Theses, Dissertations, & Professional Papers

Duvall, Alison, M.S., Autumn 2006 Environmental Studies Towards Community-Owned Forests: Landowner Perspectives on the Blackfoot Community Conservation Area Chairperson: Dr. Jill Belsky The Blackfoot Community Project is a partnership among the Blackfoot Challenge, a landowner-based watershed organization in the Blackfoot Valley and The Nature Conservancy to purchase and re-sell up to 88,092 acres of mid-elevation Plum Creek Timber Company lands to private and public interests as an alternative to subdivision and fragmentation of the landscape. In line with the project’s goal to maintain the working landscapes of the Blackfoot Valley and rural lifestyle through a “community-driven” process, the partnership has …

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Using Place Attachment To Determine The Acceptability Of Restoring Fire To Its Natural Role In Wilderness Ecosystems, Eric Paul Turbeville Jan 2006

Using Place Attachment To Determine The Acceptability Of Restoring Fire To Its Natural Role In Wilderness Ecosystems, Eric Paul Turbeville

Graduate Student Theses, Dissertations, & Professional Papers

This study was conducted to explore the social dimensions of wilderness fire management. I set out to answer the question what role does an individual’s attachment to place play in determining the acceptability of management actions directed towards fire? I feel that problems will arise if management agencies attempt to restore natural fire regimes to wilderness areas without accounting for the effects on meanings and values different people attach to landscapes. I used a qualitative method and conducted guided interviews with 27 people from three different groups: (1) fire and wilderness management personnel from the Bitterroot National Forest, (2) residents …

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Cumulonimbus On Clay| Five Letters To A Difficult Place, Jesslyn Capen Shields Jan 2006

Cumulonimbus On Clay| Five Letters To A Difficult Place, Jesslyn Capen Shields

Graduate Student Theses, Dissertations, & Professional Papers

No abstract provided.

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How Can Official Development Aid And Foreign Direct Investment Assist Developing Democracies?, Steven Kapfer Jan 2006

How Can Official Development Aid And Foreign Direct Investment Assist Developing Democracies?, Steven Kapfer

Sigma: Journal of Political and International Studies

No abstract provided.

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The Legality And Ethics Of Therapeutic Human Cloning, Justin Perry Jan 2006

The Legality And Ethics Of Therapeutic Human Cloning, Justin Perry

Brigham Young University Prelaw Review

No abstract provided.

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The Role Of Electrospinning In The Emerging Field Of Nanomedicine, S. Y. Chew, Y. Wen, Yuris A. Dzenis, K. W. Leong Jan 2006

The Role Of Electrospinning In The Emerging Field Of Nanomedicine, S. Y. Chew, Y. Wen, Yuris A. Dzenis, K. W. Leong

Department of Mechanical and Materials Engineering: Faculty Publications

The fact that in vivo the extracellular matrix or substratum with which cells interact often includes topography at the nanoscale underscores the importance of investigating cell-substrate interactions and performing cell culture at the submicron scale. An important and exciting direction of research in nanomedicine would be to gain an understanding and exploit the cellular response to nanostructures. Electrospinning is a simple and versatile technique that can produce a macroporous scaffold comprising randomly oriented or aligned nanofibers. It can also accommodate the incorporation of drug delivery function into the fibrous scaffold. Endowed with both topographical and biochemical signals such electrospun nanofibrous …

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International Committee On Harmonization Of Technical Requirements For Registration Of Pharmaceuticals For Human Use (Ich), Sarah Fowler-Dixon Jan 2006

International Committee On Harmonization Of Technical Requirements For Registration Of Pharmaceuticals For Human Use (Ich), Sarah Fowler-Dixon

Human Research Protection Program (HRPP) Education

No abstract provided.

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