Digital Commons Network^™

Mig-5/Dsh Controls Cell Fate Determination And Cell Migration In C. Elegans, Timothy Walston, Chaobo Guo, Rui Proenca, Mingfu Wu, Michael Herman, Jeff Hardin, Edward Hedgecock

School of Biological Sciences: Faculty Publications

Cell fate determination and cell migration are two essential events in the development of an organism. We identify mig-5, a Dishevelled family member, as a gene that regulates several cell fate decisions and cell migrations that are important during C. elegans embryonic and larval development. In offspring from mig-5 mutants, cell migrations are defective during hypodermal morphogenesis, QL neuroblast migration, and the gonad arm migration led by the distal tip cells (DTCs). In addition to abnormal migration, DTC fate is affected, resulting in either an absent or an extra DTC. The cell fates of the anchor cell in hermaphrodites …

Extended Visions, September/October 2006

Extended Visions Newsletter (ARDC)

Contents:
ARDC Director's Comments
ARDC FEATURE UNIT - Veterinary and Biomedical Science
About the People
Research Essential In Disease Prevention
Eating Healthy On the Go: Is that Possible?
Calendar of Events
National Conservation Group Visits ARDC
Soils & Manure Phosphorus Lessons Available Online
Mead Magnet School Update
Mead FFA Monitors Farmers’ Fields with Sticky Traps
Upcoming Workshops For Acreage Owners
Windbreak Renovation and Pine Wilt Disease
Fall Landscape Management Workshop

Interval Timer Control Of Puberty In Photoinhibited Siberian Hamsters, Ho Park Jin, Alexander S. Kauffman, Matthew J. Paul, Matthew P. Butler, Annaliese K. Beery, Ruth M. Costantini, Irving Zucker

Neuroscience: Faculty Publications

Puberty, which is markedly delayed in male Siberian hamsters (Phodopus sungorus) born into short day lengths, is controlled by an interval timer regulated by the duration of nocturnal melatonin secretion. Properties of the interval timer were assessed by perturbing normal patterns of melatonin secretion in males gestated and maintained thereafter in 1 of 2 short day lengths, 10 h light/day (10L) or 12L. Melatonin secretion of short-day hamsters was suppressed by constant light treatment or modified by daily injection of propranolol to mimic nocturnal melatonin durations typical of long-day hamsters. Constant light treatment during weeks 3 to 5 induced early …

Microparticulate Drug Reformulation Using Electrostatic Layer -By -Layer Assembly And Co-Entrapment With Anionic Phospholipids In Calcium Carbonate Matrix, Krishna Gopal

Doctoral Dissertations

Non-invasive drug delivery systems for therapeutic drugs are gaining prominence. One such system, the nasal delivery system, shows good prospect for effective delivery of some drugs, however, it is yet to be well established for others. The preparation of a reformulated drug and studying its in vitro characteristics is a crucial step in the process of adapting the new drug for nasal delivery systems. The purpose of this research is to study the effect of electrostatic layer by layer assembly of polyelectrolytes on PROMAXX®insulin microparticles and to study the chemical, physical and corresponding release properties of the resulting formulations. PROMAXX® …

Mild Cognitive Impairment, Activity Participation, Functional Difficulty, & Adaptations , Laraine Winter, Laura N. Gitlin

Center for Applied Research on Aging and Health Research Papers

No abstract provided.

Managing Liquid Dairy Manure, José R. Bicudo

Agricultural Engineering Extension Publications

One of the primary issues in the dairy production industry is the storage, management, and land application of manure. Producers should plan how and when to apply manure to agricultural land to minimize the risk of water pollution and odor nuisance and maximize nutrient use.

Lipin Expression Is Attenuated In Adipose Tissue Of Insulin-Resistant Human Subjects And Increases With Peroxisome Proliferator-Activated Receptor Γ Activation, Aiwei Yao-Borengasser, Neda Rasouli, Vijayalakshmi Varma, Lesliie M. Miles, Bounleut Phanavanh, Tasha Starks, Jack Phan, Horace J. Spencer Iii, Robert E. Mcgehee Jr., Karen Reue, Philip A. Kern

Clinical and Translational Science Faculty Publications

Lipin-α and -β are the alternatively spliced gene products of the Lpin1 gene, whose product lipin is required for adipocyte differentiation. Lipin deficiency causes lipodystrophy, fatty liver, and insulin resistance in mice, whereas adipose tissue lipin overexpression results in increased adiposity but improved insulin sensitivity. To assess lipin expression and its relation to insulin resistance in humans, we examined lipin-α and -β mRNA levels in subjects with normal or impaired glucose tolerance. We found higher expression levels of both lipin isoforms in lean, insulin-sensitive subjects. When compared with normal glucose-tolerant subjects, individuals with impaired glucose tolerance were more insulin resistant, …

Community, Fall 2006, Office Of Communications And Marketing, Wright State University

Community

Forty-two page issue of Community which was published periodically from 1996 through 2011. The magazine focused on news and events at Wright State University relating to faculty, staff, alumni, and friends of the university.

Contemporary Slavery In The Amazon Of Maranhão: Reality And Response, Landen Romei

Independent Study Project (ISP) Collection

This research project addresses the reality of contemporary slavery in the Amazon of Maranhão. Through observations at the Center of Defense of Life and Human Rights (CDVDH) in the municipality of Açailândia, it gains a sense of the combat against the usage of slave labor today. Interviews with staff members at the Center and its Cooperative explain their objectives and methods in this struggle. In addition, interviews with former slaves allow for a deeper understanding of the day-to-day life of a modern slave. Over the course of three weeks of field research, the hypothesis of the gravity of slavery and …

Hyaluronidase Expression Induces Prostate Tumor Metastasis In An Orthotopic Mouse Model, Joy L. Kovar, Mark A. Johnson, William M. Volcheck, Jiyan Chen, Melanie A. Simpson

Department of Biochemistry: Faculty Publications

Molecular mechanisms of prostate cancer progression are frequently studied in mice by orthotopic injection of aggressive cell lines, which yield primary tumors that spontaneously metastasize to lymph nodes. In this report, we characterized the human prostate carcinoma cell line 22Rv1 in an orthotopic system and evaluated the functional relevance of the hyaluronidase Hyal1, a correlate of invasive human prostate cancer, to progression in this model. To provide real-time insights into these processes, we first validated use of an epidermal growth factorconjugated fluorophore to illuminate orthotopic prostate tumors and their metastases in whole animal imaging. Animals receiving intraprostatic injections were tracked …

Otterbein Towers Fall 2006, Otterbein Towers

Towers Magazine

Ground Zero; Features: Otterbein’s Fiscal 2006 Report; Inside the Forbidden City; Speech & Theatre Turns 100; Regulars: College News: Dept. of Art has a New Home; New Residence Hall for Sophomores; Phonathon gets a Permanent Home; Good News about IRAs; Otterbein again RankedHigh Academically; Classnotes; Letters; Milestones; Investing in Otterbein; Alumni Notes, etc.

Mild Cognitive Impairment, Activity Participation, Functional Difficulty, And Adaptations In Functionally Vulnerable Elderly People: A Closer Look, Laraine Winter, Laura N. Gitlin

Center for Applied Research on Aging and Health Research Papers

No abstract provided.

Literacy Assessment New Zealand Style, Thomas R. Guskey, Jeffrey K. Smith, Lisa F. Smith, Terry Crooks, Lester Flockton

Educational, School, and Counseling Psychology Faculty Publications

It's mostly performance based. It assesses students in teams as well as individually. What's more, students like it.

Liberty Of Ecological Conscience, Aaron Lercher

Faculty Publications

Our concern for nonhuman nature can be justified in terms of a human right to liberty of ecological conscience. This right is analogous to the right to religious liberty, and is equally worthy of recognition as that fundamental liberty. The liberty of ecological conscience, like religious liberty, is a negative right against interference. Each ecological conscience supports a claim to protection of the parts of nonhuman nature that are current or potential sites of its active pursuit of natural value. If we acknowledge the fallibility of each conscience in its pursuit of genuine natural value, a policy of indefinitely extensive …

Com Outlook Fall 2006, College Of Osteopathic Medicine

COM Outlook

No abstract provided.

Best Books Of The Decade For Children And Young Adults, Rachel Schwedt, Janice A. Delong

Faculty Publications and Presentations

With 250,000 titles on the market, teachers, librarians, and parents have an enormous challenge before them to choose the best books for the young people in their care. This presentation focuses on books for elementary and high school students, which have won state, national, or international awards within the past ten years.

The Immorality And Inefficiency Of An Efficient Breach, Dawinder S. Sidhu

Transactions: The Tennessee Journal of Business Law

No abstract provided.

Children’S Use Of Retreats In Family Child Care Homes, Nanci Weinberger

Applied Psychology Department Faculty Journal Articles

The use of retreat spaces by 65 children in 9 family child care homes was assessed in this study. Family child care providers used daily diaries to collect information about children’s retreat frequency and associated behavior. The findings revealed that nearly half of the children used informal, readily available retreats during the research period. Playing with toys was the most frequent and stable retreat activity across age groups. Yet the number of passive and engaged behaviors varied based on child characteristics such as age, gender, and child’s mood for the day. Retreat use can be viewed as a potentially adaptive …

Focus, Bob Evancho (Editor)

FOCUS on Boise State

Boise State University is actively engaged in efforts to address some of the major challenges of the day, including global warming, terrorism, immigration and health concerns. Faculty research extends far beyond the boundaries of the university or the state of Idaho and involves resources, energy and collaboration from entities across the globe. Cover photo of Boise State history professor Mike Zirinsky with pre-revolutionary Iranian flag by John Kelly.

Opinion Of The Attorney General State Of South Carolina, Henry Mcmaster

Southeastern Environmental Law Journal

No abstract provided.

Ecosystem Services And The Public Trust Doctrine: Working Change From Within, J. B. Ruhl, James Salzman

Southeastern Environmental Law Journal

No abstract provided.

Grand Valley Magazine, Vol. 6, No. 1 Fall 2006, Grand Valley State University

Grand Valley Magazine

Grand Valley Magazine is a quarterly publication about Grand Valley State University produced by University Communications since 2001.

F06rs Sgr No. 3 (Cristina Hnatyshyn), Dubois, Mizell, Robertson

Student Senate Enrolled Legislation

A RESOLUTION

to express the sincere and heartfelt condolences of the College of Agriculture of the Louisiana State University to the family of animal, dairy and poultry sciences freshman Cristina Hnatyshyn upon her death.

Constitutional Referendum In The United States Of America, William B. Fisch

Faculty Publications

The United States of America, as a federation of now 50 states each with its own constitution and legal system still enjoying a large degree of governmental autonomy within the national legal framework, presents a strikingly mixed picture regarding the use of direct democracy--the submission of proposed governmental action to a popular vote--in law- and constitution-making processes. At the national level, direct democracy has never been used for either type of enactment. At the state and local level, however, its use dates back to colonial times and has been increasing gradually (though still not universal) ever since. Since the mid-19th …

Land Use Dynamics And Policy Implications In The Jinghe Watershed Of Western China: A Critical Assessment From Local Perspectives, Lin Zhen, Li Yang, Gaodi Xie, Shengkui Cheng

Natural Resources Journal

No abstract provided.

How Does A Child With Sensory Processing Problems Play?, Jeryl D. Benson, Meghana N. Nicka, Perri Stern

Internet Journal of Allied Health Sciences and Practice

The occupation of play during one’s childhood years serves as a foundation for the development of future occupations in an individual’s life. By understanding a child’s extant play skills and deficits, one may then provide the necessary interventions needed to promote development and successful growth into new occupations. The purpose of this paper was to understand how a child with sensory processing deficits plays in a naturalistic environment. The findings revealed an interplay between the child’s underlying sensory processing deficits and his play skills and behaviors. Increased understanding of how a child with sensory processing deficits plays will provide information …

Commandeering And Its Alternatives: A Federalism Perspective, Neil S. Siegel

Vanderbilt Law Review

This inquiry argues that current Tenth Amendment jurisprudence causes net harm to federalism values under certain circumstances. Specifically, New York v. United States and Printz v. United States protect state autonomy to some extent by requiring the federal government to internalize more of the costs of federal regulation before engaging in regulation. But anticommandeering doctrine harms state autonomy in situations where the presence of the rule triggers more preemption going forward. Preemption generally causes a greater compromise of federalism values than does commandeering by eroding state regulatory control.

While it is a context-sensitive empirical question whether specific applications of the …

Transcutaneous Immunization With Toxin-Coregulated Pilin A Induces Protective Immunity Against Vibrio Cholerae O1 El Tor Challenge In Mice, Julianne E. Rollenhagen, Anuj Kalsy, Francisca Cerda, Manohar John

Dartmouth Scholarship

Toxin-coregulated pilin A (TcpA) is the main structural subunit of a type IV bundle-forming pilus of Vibrio cholerae, the cause of cholera. Toxin-coregulated pilus is involved in formation of microcolonies of V. cholerae at the intestinal surface, and strains of V. cholerae deficient in TcpA are attenuated and unable to colonize intestinal surfaces. Anti-TcpA immunity is common in humans recovering from cholera in Bangladesh, and immunization against TcpA is protective in murine V. cholerae models. To evaluate whether transcutaneously applied TcpA is immunogenic, we transcutaneously immunized mice with 100 mug of TcpA or TcpA with an immunoadjuvant (cholera toxin [CT], …

The Effects Of Tgf-Beta1 And Igf-I On The Biomechanics And Cytoskeleton Of Single Chondrocytes, Nic Leipzig

Chemical, Biomolecular, and Corrosion Engineering Faculty Research

Objective Ascertaining how mechanical forces and growth factors mediate normal and pathologic processes in single chondrocytes can aid in developing strategies for the repair and replacement of articular cartilage destroyed by injury or disease. This study examined effects of transforming growth factor-β1 (TGF-β1) and insulin-like growth factor-I (IGF-I) on the biomechanics and cytoskeleton of single zonal chondrocytes. Method Superficial and middle/deep bovine articular chondrocytes were seeded on tissue culture treated plastic for 3 and 18 h and treated with TGF-β1 (5 ng/mL), IGF-I (100 ng/mL), or a combination of TGF-β1 (5 ng/mL) + IGF-I (100 ng/mL). Single chondrocytes from all …

Brazil's Ip Opportunism Threatens U.S. Private Property Rights, Lawrence A. Kogan

University of Miami Inter-American Law Review

No abstract provided.