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2005

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The Effects Of Postindustrial Employment Configurations On Father-Child Involvement In Urban Fragile Families, Michael G. Cina Jan 2005

The Effects Of Postindustrial Employment Configurations On Father-Child Involvement In Urban Fragile Families, Michael G. Cina

Graduate Theses, Dissertations, and Problem Reports (ETD)

Research shows that many inner city fathers work a variety of jobs to make a living for themselves and their families. While some fathers work in traditional jobs that are regulated and taxed, others generate income "off-the-books" or through illegal work called "hustles." This thesis uses data from the Fragile Families and Child Wellbeing Study to assess the impact of hours worked in regular jobs, off-the-books ventures, and illicit hustles on fathers' involvement with their eighteen-month old child. The regression results show that fathers who spend increasing hours hustling tend to be less involved with their children than fathers who …

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Osteotropic Cytokines Mediate Human Osteoblast-Like Cell Eicosanoid Production, Anurag Grover Jan 2005

Osteotropic Cytokines Mediate Human Osteoblast-Like Cell Eicosanoid Production, Anurag Grover

Graduate Theses, Dissertations, and Problem Reports (ETD)

We have examined the effects of the cytokines tumor necrosis factoralpha (TNF), transforming growth factorbeta (TGFbeta) and the effect of cyclooxygenase inhibitor ibuprofen on prostaglandin and 15-HETE biosynthesis by normal adult human osteoblast-like (hOB) cells. In the present studies, conditioned media harvested from hOB cell cultures were assayed by eicosanoid specific EIAs to determine quantitatively the effects of cytokines on PGE2, 6-keto-PGF1alpha, PGF2alpha, PGD2, thromboxane (TXB2) and on 15-HETE biosynthesis. EIA analysis indicated that PGE2 was the predominant PG metabolite released by unstimulated hOB cells and its synthesis was increased more than other PGs in cells treated with (TGFbeta) and …

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Assessing The Cost-Effectiveness Of Tumor Necrosis Factor Inhibitors And Prescribing Practices Of Rheumatologists In Patients With Rheumatoid Arthritis, Khalid M. Kamal Jan 2005

Assessing The Cost-Effectiveness Of Tumor Necrosis Factor Inhibitors And Prescribing Practices Of Rheumatologists In Patients With Rheumatoid Arthritis, Khalid M. Kamal

Graduate Theses, Dissertations, and Problem Reports (ETD)

Three new tumor necrosis factor (TNF) inhibitors, adalimumab, etanercept, and infliximab, have been approved for use in patients with active RA. The goals of the study were two fold: (1) to perform a cost-effectiveness analysis of the three TNF inhibitors in patients with RA that inadequately respond to MTX alone and (2) to assess the current prescribing patterns, laboratory monitoring practices, and perceived barriers of rheumatologists in prescribing these agents in patients with RA. Phase I involved the development of a Markov simulation model to estimate the health effects and costs associated with five treatment strategies in patients with RA …

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Suicide And Socioeconomic Context In The Appalachian Region, Joel A. Halverson Jan 2005

Suicide And Socioeconomic Context In The Appalachian Region, Joel A. Halverson

Graduate Theses, Dissertations, and Problem Reports (ETD)

Significant economic changes have occurred over the past thirty years that have altered the geoeconomic landscape of the United States. Although a considerable literature examines economic impacts that have resulted from these changes, there has been less work devoted to understanding the extraeconomic affects of economic change. Many places in the U.S. have experienced large-scale employment and industry losses over the past thirty years. At the same time some places have experienced rapid industrial and employment growth. Together these events represent the continued process of geographic uneven development and provide the context for examining potential affects that economic conditions and …

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Heat Shock Protein 70 As An Indicator Of Toxic Heavy Metal Exposure And Oxidative Stress In The Serum Of Asymptomatic Shipyard Welders, Sung Gu Han Jan 2005

Heat Shock Protein 70 As An Indicator Of Toxic Heavy Metal Exposure And Oxidative Stress In The Serum Of Asymptomatic Shipyard Welders, Sung Gu Han

Graduate Theses, Dissertations, and Problem Reports (ETD)

Heat shock protein 70 (Hsp70) expression has been reported to be a sensitive biomarker of cell stress. Arsenic (As), cadmium (Cd), mercury (Hg), chromium (Cr), nickel (Ni), vanadium (V), and manganese (Mn) are widely used and exposure to these metals is associated with the development of pulmonary disease. Our data showed that exposure to these metals resulted in a significant increase in cytotoxicity, apoptosis, and generation of reactive oxygen species (ROS) in a human bronchial cell line, BEAS-2B. However, increased Hsp70 expression was observed only in cells exposed to As, Cd, and Hg. To correlate changes associated with Hsp70 overexpression, …

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Analysis Of Aging Effects And Effectiveness Of Dewatering Treatment Methods On Acid Mine Drainage Sludge, Phanindra Kumar V. Kunderu Jan 2005

Analysis Of Aging Effects And Effectiveness Of Dewatering Treatment Methods On Acid Mine Drainage Sludge, Phanindra Kumar V. Kunderu

Graduate Theses, Dissertations, and Problem Reports (ETD)

Acid Mine Drainage (AMD) is produced when sulfide minerals in overburden are subjected to oxygen and water, and generally contains low pH, high acidity and high dissolved metal concentrations. Typically, active treatment of AMD involves the addition of a neutralizing reagent to raise the pH and precipitate the metals as their respective insoluble metal hydroxides. As a by-product of the active treatment of AMD, a large amount of sludge is generated. A site, established in Monongalia County, WV for the active treatment of AMD using ammonia and hydrogen peroxide, generated sludge consisting mainly of water with a total solids concentration …

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Analysis Of Physiological Partners Of Protein Kinase Ck2 In Drosophila Melanogaster, Umesh C. Karandikar Jan 2005

Analysis Of Physiological Partners Of Protein Kinase Ck2 In Drosophila Melanogaster, Umesh C. Karandikar

Graduate Theses, Dissertations, and Problem Reports (ETD)

CK2 is a highly conserved Ser/Thr protein kinase composed of catalytic (alpha) and regulatory (beta) subunits. The enzyme targets proteins that are involved in a variety of cellular processes such as DNA replication, transcription, translation, cell cycle progression, and development. However, very little information is available on either the regulation of this enzyme or its role during development. These two aspects of CK2 have been addressed using the fruit fly, Drosophila melanogaster, as a model organism. The first study (chapter 2) addresses the isolation and characterization of SSL, an ortholog of CK2beta. Using combinatorial approaches, we find that SSL associates …

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Graph Algorithms For The Haplotyping Problem, Yunkai Liu Jan 2005

Graph Algorithms For The Haplotyping Problem, Yunkai Liu

Graduate Theses, Dissertations, and Problem Reports (ETD)

Evidence from investigations of genetic differences among human beings shows that genetic diseases are often the results of genetic mutations. The most common form of these mutations is single nucleotide polymorphism (SNP). A complete map of all SNPs in the human genome will be extremely valuable for studying the relationships between specific haplotypes and specific genetic diseases. Some recent discoveries show that the DNA sequence of human beings can be partitioned into long blocks where genetic recombination has been rare. Then, inferring both haplotypes from chromosome sequences is a biologically meaningful research topic, which has compounded mathematical and computational problems.;We …

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Amending Subsoil With Composted Poultry Litter: Effects On Soil Physical And Chemical Properties, Turfgrass Establishment And Weed Pressure, Mili Mandal Jan 2005

Amending Subsoil With Composted Poultry Litter: Effects On Soil Physical And Chemical Properties, Turfgrass Establishment And Weed Pressure, Mili Mandal

Graduate Theses, Dissertations, and Problem Reports (ETD)

Experiments were established in fall 2003 at West Virginia University to evaluate the effects of incorporation of composted poultry litter (CPL) on subsoil physical and chemical properties, Kentucky bluegrass ( Poa Pratensis L.) establishment, root depth, and weed pressure. Twenty cm of topsoil was removed and CPL was incorporated to a depth of 12.7 cm at 10%, 20%, and 40% v/v prior to seeding or sodding. Composted plots were compared to N-fertilized (454 Kg ha-1) and control plots. Positive linear increases in total water content (thetaT), organic matter, pH, and CEC were observed following compost incorporation with a decrease in …

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Three Essays On Immigration And Outsourcing, Arsen V. Melkumian Jan 2005

Three Essays On Immigration And Outsourcing, Arsen V. Melkumian

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation includes essays on legal and illegal immigrations and outsourcing. Chapter 1 introduces the paths that economics has blazed into in the areas of legal and illegal immigration and outsourcing. The first essay, in Chapter 2, presents a Cournot duopoly model of a domestic unionized firm and a foreign firm, where the domestic firm has an option to shift all of its production abroad. An increase in the bargaining power of an employment oriented union will increase domestic output and utility of the union.;The second essay, in Chapter 3, examines illegal immigration in the U.S. from Mexico using annual …

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Data Mining Framework, Hemambika Payyappillil Jan 2005

Data Mining Framework, Hemambika Payyappillil

Graduate Theses, Dissertations, and Problem Reports (ETD)

The purpose of this document is building a framework for working with clinical data. Vast amounts of clinical records, stored in health repositories, contain information that can be used to improve the quality of health care. However, the information generated from these records depends vastly on the manner, in which the data is arranged. A number of factors need to be considered, before information can be extracted from the patient records. This document deals with the preparation of a framework for the data, before it can be mined.;One of the issues to deal with is information about the patient contained …

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Using Gis And Landowner Survey To Determine If The Forest Stewardship Program Is Effective At Generating Involvement In Forest Health Issues In West Virginia, David Page Mccann Jan 2005

Using Gis And Landowner Survey To Determine If The Forest Stewardship Program Is Effective At Generating Involvement In Forest Health Issues In West Virginia, David Page Mccann

Graduate Theses, Dissertations, and Problem Reports (ETD)

A risk rating map created from 22 shapefiles of pest and disease activity data was used to produce maps of individual properties distributed to half of survey subjects along with a postcard questionnaire. In total, 933 landowners were surveyed; 21% responded. The affects of three factors---the Forest Stewardship Program (FSP), region, and a map---on landowner interest were investigated using ANOVA and logistic regression. The affects of covariables risk rating and acreage were evaluated using ANCOVA. Logistic regression identified preferred delivery methods and pests and diseases relevant to landowners. FSP participation significantly affected interest level, the selection of gypsy moth, and …

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Characterization Of Noise And Design Of Active Noise Control Technology In Longwall Mines, Arunkumar R. Rai Jan 2005

Characterization Of Noise And Design Of Active Noise Control Technology In Longwall Mines, Arunkumar R. Rai

Graduate Theses, Dissertations, and Problem Reports (ETD)

Production and safety have always been a prime issue for mining industry and mining engineers, who strive hard to achieve the critical balance between them. Hearing loss and uneasy working environment are few common ones affecting the health statistics of a underground mine. As a result, recent years there have been the focus on to develop an engineering controls to reduce the underground noise. Unique work has been done in this thesis to add additional information on the active noise control technology applied to Longwall mining operations.;Mostly, the survey results indicated that the frequency content of each noise and the …

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Quality Of Life And Clinical Outcomes In Type 2 Diabetes Patients At The Primary Care Clinics Of The West Virginia University Hospital, Murali Sundaram Jan 2005

Quality Of Life And Clinical Outcomes In Type 2 Diabetes Patients At The Primary Care Clinics Of The West Virginia University Hospital, Murali Sundaram

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study examines relationships between quality of life (QoL) and clinical outcomes, specifically A1C, in Type 2 diabetes patients. Type 2 diabetes patients at the outpatient clinics of a university hospital completed the SF-12 and the Audit of Diabetes Dependent Quality of Life (ADDQoL), and this was merged with a retrospective collection of his/her clinical and utilization data, including A1C. Usable response rate was 44.3% (n = 385). Mean A1C of respondents was 7.2 (+1.4), mean diabetes duration was 10.2 (+9.1), and 62.1% were obese. Only ADDQoL scores showed significant correlation with A1C (r = -0.19, p < 0.000). Hierarchical regression models were used to explain the effect of A1C on QoL controlling for demographics and clinical variables. A1C was not a significant predictor in any regression model, although univariate analyses indicated significantly lower ADDQoL and SF-12 PCS in the group with A1C > 7.0. Obesity was …

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Mandated Healthcare Will It Work?, Anna Vira Jan 2005

Mandated Healthcare Will It Work?, Anna Vira

Seton Hall University Dissertations and Theses (ETDs)

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Characterization Of Migrating Cells From Ventricular Zone (Vz) To Distant Limbic Structures After Multiple Neonatal Seizures, Melissa Corcia Jan 2005

Characterization Of Migrating Cells From Ventricular Zone (Vz) To Distant Limbic Structures After Multiple Neonatal Seizures, Melissa Corcia

Seton Hall University Dissertations and Theses (ETDs)

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A Study Of Job Satisfaction Among High School Principals In Pennsylvania, Robert Lombardo Jan 2005

A Study Of Job Satisfaction Among High School Principals In Pennsylvania, Robert Lombardo

Seton Hall University Dissertations and Theses (ETDs)

The purpose of this study was to determine the overall job satisfaction of high school principals in Pennsylvania. The Minnesota Job Satisfaction Questionnaire long form was the instrument used for this study. The study used a proportional random sampling to survey the four hundred and twenty six high school principals in Pennsylvania. The study surveyed two hundred and twenty five male high school principals and eighty female high school principals. The study determined the level of intrinsic and extrinsic satisfaction and determined the relationship of selected factors of gender; age; ethnicity; levels of education; salary level; years of experience; number …

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The Effect Of Microcurrent Stimulation On Atp Synthesis In The Human Masseter As Evidenced By 31p Magnetic Resonance Spectroscopy, Jeffrey S. Mannheimer Jan 2005

The Effect Of Microcurrent Stimulation On Atp Synthesis In The Human Masseter As Evidenced By 31p Magnetic Resonance Spectroscopy, Jeffrey S. Mannheimer

Seton Hall University Dissertations and Theses (ETDs)

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Does Dtc Advertising Strengthen Our Healthcare System, Michael S. Lillo Jan 2005

Does Dtc Advertising Strengthen Our Healthcare System, Michael S. Lillo

Seton Hall University Dissertations and Theses (ETDs)

No abstract provided.

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Bulimia And Binge-Eating-Disorder And Their Relationship To Family Characteristics, Attachment, Depression, And Self-Esteem, Barbara Brennan Ferguson Jan 2005

Bulimia And Binge-Eating-Disorder And Their Relationship To Family Characteristics, Attachment, Depression, And Self-Esteem, Barbara Brennan Ferguson

Seton Hall University Dissertations and Theses (ETDs)

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Communication Skills In Girls With Rett Syndrome: Perceptions Of Parents, Teachers And Speech-Language Pathologists, Theresa E. Bartolotta Jan 2005

Communication Skills In Girls With Rett Syndrome: Perceptions Of Parents, Teachers And Speech-Language Pathologists, Theresa E. Bartolotta

Seton Hall University Dissertations and Theses (ETDs)

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Female Athletes And Performance-Enhancer Usage, Barbara Kay Fralinger Jan 2005

Female Athletes And Performance-Enhancer Usage, Barbara Kay Fralinger

Seton Hall University Dissertations and Theses (ETDs)

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Aircraft Cabin Noise Minimization Via Neural Network Inverse Model, Xiao Hu, G. Clark, M. Travis, J. L. Vian, Donald C. Wunsch Jan 2005

Aircraft Cabin Noise Minimization Via Neural Network Inverse Model, Xiao Hu, G. Clark, M. Travis, J. L. Vian, Donald C. Wunsch

Electrical and Computer Engineering Faculty Research & Creative Works

This paper describes research to investigate an artificial neural network (ANN) approach to minimize aircraft cabin noise in flight. The ANN approach is shown to be able to accurately model the non-linear relationships between engine unbalance, airframe vibration, and cabin noise to overcome limitations associated with traditional linear influence coefficient methods. ANN system inverse models are developed using engine test-stand vibration data and on-airplane vibration and noise data supplemented with influence coefficient empirical data. The inverse models are able to determine balance solutions that satisfy cabin noise specifications. The accuracy of the ANN model with respect to the real system …

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Adviser's Guide To Health Savings Accounts, Gary S. Lesser, Christine L. Keller, Susan D. Diehl Jan 2005

Adviser's Guide To Health Savings Accounts, Gary S. Lesser, Christine L. Keller, Susan D. Diehl

Guides, Handbooks and Manuals

No abstract provided.

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Elevated Ex Vivo Monocyte Chemotactic Protein-1 (Ccl2) In Pulmonary As Compared With Extra-Pulmonary Tuberculosis, Zahra Hasan, Irfan Zaidi, Bushra Jamil, M Aslam Khan, Akber Kanji, Rabia Hussain Jan 2005

Elevated Ex Vivo Monocyte Chemotactic Protein-1 (Ccl2) In Pulmonary As Compared With Extra-Pulmonary Tuberculosis, Zahra Hasan, Irfan Zaidi, Bushra Jamil, M Aslam Khan, Akber Kanji, Rabia Hussain

Department of Pathology and Laboratory Medicine

Background: Tuberculosis causes 3 million deaths annually. The most common site of tuberculosis is pulmonary however; extra-pulmonary forms of the disease also remain prevalent. Restriction of Mycobacterium tuberculosis depends on effective recruitment and subsequent activation of T lymphocytes, mononuclear and polymorphonuclear cells to the site of infection. Tumor necrosis factor (TNF)-α is essential for granuloma formation and is a potent activator of monocyte chemotactic protein (MCP-1, CCL2). CCL2 is essential for recruitment of monocytes and T cells and has been shown to play a role in protection against tuberculosis. Interleukin -8 (CXCL8) is a potent activator of neutrophils. Increased …

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Frequency Of Irregular Red Cell Alloantibodies In Patients With Thalassemia Major: A Bicenter Study, Fareena Bilwani, Ghulam Nabi, Salman Adil, Mohammad Usman, Farrukh Hassan, Mohammad Khurshid Jan 2005

Frequency Of Irregular Red Cell Alloantibodies In Patients With Thalassemia Major: A Bicenter Study, Fareena Bilwani, Ghulam Nabi, Salman Adil, Mohammad Usman, Farrukh Hassan, Mohammad Khurshid

Department of Pathology and Laboratory Medicine

Objective: To provide frequency and distribution pattern of various types of irregular red cell alloantibodies in patients with thalassemia major.
Methods: This is a descriptive study conducted at two centers from January to December 2001. Purposive sampling was done and all patients diagnosed to have thalassemia major were included in the study. Antibody identification was carried out on serum employing commercial two-cell panel using standardized blood bank methods. If patients were found to have an irregular red cell alloantibody then the antibody identification was performed using 16 panel cells. Results: A total of ninety-seven patients were included …

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Anaphylactic Reaction After Intramuscular Injection Of Cyanocobalamin (Vitamin B12): A Case Report, Fareena Bilwani, Salman Adil, Usman Sheikh, Ayesha Humera, Mohammad Khurshid Jan 2005

Anaphylactic Reaction After Intramuscular Injection Of Cyanocobalamin (Vitamin B12): A Case Report, Fareena Bilwani, Salman Adil, Usman Sheikh, Ayesha Humera, Mohammad Khurshid

Department of Pathology and Laboratory Medicine

We report a case of anaphylactic reaction to intramuscular injection of cyanocobalamin. This 52-year-old lady was diagnosed as a case of megaloblastic anemia secondary to dietary vitamin B12 deficiency. She had severe anaphylactic reaction after the parenteral administration of cyanocobalamine. Later she received oral vitamin B12 with no adverse effects. The purpose of this case report is to draw attention to the hypersensitive reaction to injectable vitamin B12, which is rarely seen. This could be due to sensitization to the vitamin B12 molecule itself or an IgE mediated reaction. We concluded that anaphylactic reaction to vitamin B12 is a rare …

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Hairy Cell Leukemia: Clinical Presentation And Long Term Follow Up After Treatment With 2-Chlorodeoxyadenosine (2-Cda), Fareena Bilwani, Mohammad Usman, Salman Adil, Ghulam N. Kakepoto, Mohammad Khurshid Jan 2005

Hairy Cell Leukemia: Clinical Presentation And Long Term Follow Up After Treatment With 2-Chlorodeoxyadenosine (2-Cda), Fareena Bilwani, Mohammad Usman, Salman Adil, Ghulam N. Kakepoto, Mohammad Khurshid

Department of Pathology and Laboratory Medicine

The aim of the study was to the clinical features and long term follow up after treatment with Cladarbine in a tertiary care hospital. Seven patients with hairy cell leukemia were diagnosed between January 1990 till December 2003. Diagnosis in all the patients was established by bone marrow aspirates and trephine biopsy along with TRAP. In two patients the diagnosis was supplemented by flowcytometry and in another two patients by splenectomy. Six patients were male while one was female. Mean age was 47.7 years (range 36-64). Most common presenting features were pallor and weakness (n=5). All patients had splenomegaly. Blood …

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Frequency Of Fab Subtypes In Acute Myeloid Leukemia Patients At Aga Khan University Hospital Karachi, Mahadev Sajanmal Harani, Salman Adil, Mohammad Usman Shaikh, G N Kakepoto, Mohammad Khurshid Jan 2005

Frequency Of Fab Subtypes In Acute Myeloid Leukemia Patients At Aga Khan University Hospital Karachi, Mahadev Sajanmal Harani, Salman Adil, Mohammad Usman Shaikh, G N Kakepoto, Mohammad Khurshid

Department of Pathology and Laboratory Medicine

BACKGROUND: Acute myeloid leukemia (AML) is a heterogeneous disease. Therefore, various parameters are needed to classify this disease into subtypes, so that specific treatment approaches can be utilized effectively. The commonly used method for diagnosis and classification is based on FAB criteria using morphology and cytochemical stains. For some of the categories, immunophenotyping is necessary. The aim of present study is to determine the frequency of various sub types in acute myeloid leukemia using FAB criteria in our population. This will aid in the correct diagnosis of acute leukemia and hence proper management of the patients.
MATERIALS AND METHODS …

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Georgia Southern University Fact Book, Georgia Southern University Jan 2005

Georgia Southern University Fact Book, Georgia Southern University

Georgia Southern Fact Books (1976-2022)

No abstract provided.

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