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2005

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Type-5 Phosphodiesterase Inhibition In The Prevention Of Doxorubicin Cardiomyopathy, Patrick William Fisher Jan 2005

Type-5 Phosphodiesterase Inhibition In The Prevention Of Doxorubicin Cardiomyopathy, Patrick William Fisher

Theses and Dissertations

Prior studies have demonstrated the effect of diazoxide in protecting against apoptosis via mitochondrial KATP channel opening in vitro. The current investigations are designed to determine if sildenafil, a phosphodiesterase-5 inhibitor and known mitochondrial KATP channel opener, would protect against chronic doxorubicin cardiomyopathy both in vivo and in vitro.Male ICR mice were randomized to 1 of 4 treatments: saline, sildenafil (0.7 mg/kg IP), doxorubicin (5 mg/kg IP), and sildenafil (0.7 mg/kg IP)+doxorubicin. Apoptosis was determined using the terminal deoxynucleotidyl transferase mediated dUTP nick-end labeling and in situ oligo ligation methods. Desmin distribution was determined via immunofluorescence. Bcl-2 was analyzed by …

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Realism, Freedom, And The Integral Development Of The Human Person: A Catholic View Of Education, Michael A. Scaperlanda Jan 2005

Realism, Freedom, And The Integral Development Of The Human Person: A Catholic View Of Education, Michael A. Scaperlanda

Faculty Articles

No abstract provided.

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Literature Review: Diagnostic Utility Of The Million Clinical Multiaxial Inventories In Various Settings : The Detection And Effect Of Faking Good ; Research Project : The Impact Of Faking-Good On The Mcmi-Iii : Implications For Child Custody Evaluations, Paul Lenny Jan 2005

Literature Review: Diagnostic Utility Of The Million Clinical Multiaxial Inventories In Various Settings : The Detection And Effect Of Faking Good ; Research Project : The Impact Of Faking-Good On The Mcmi-Iii : Implications For Child Custody Evaluations, Paul Lenny

Theses : Honours

Research surrounding the ability of the Millon Clinical Multiaxial Inventory (MCMI; Millon, 1977, 198 7, 1994) to detect faking good was reviewed; along with the effect faking has on diagnostic accuracy. Limited research indicates moderate success of the MCMI validity indices (VI) at detecting faking good. Suggested improvements include developing a fake-good profile combining the personality scales and VI and developing new base rate adjustments with populations likely to fake good. Faking good reduces the overall diagnostic accuracy of the test but determining local base rates of faking to produce optimal cut-offs for the VI would improve diagnostic utility. Future …

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Mothers' Social Framing, Frequency Of Mother-Child Conversations About Peers, And Preschool Aged Children's Attribution Tendencies, Lisa Lemme Jan 2005

Mothers' Social Framing, Frequency Of Mother-Child Conversations About Peers, And Preschool Aged Children's Attribution Tendencies, Lisa Lemme

Theses : Honours

In an attempt to fill a gap in the social information processing literature, the present study investigated whether mother-child communication is related to children's attribution tendencies in ambiguous, negative social situations. Measures of mothers' social framing, frequency of mother-child conversations about peers, and children's hostile attributions of intent were scored for 45 mother-child dyads. The results showed that mothers' social framing was a key predictor of preschool children's attribution tendencies. However, frequency of mother-child conversations about peers was not a significant predictor of preschool children's attribution tendencies. Overall, the results of this study provide support for mothers' social framing as …

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The Effect Of Antioxidant Supplementation On Human Sperm Cryopreservation, Katrina E. Taylor Jan 2005

The Effect Of Antioxidant Supplementation On Human Sperm Cryopreservation, Katrina E. Taylor

Theses : Honours

Semen cryopreservation has an important role in assisted reproductive technology however, the cooling, freezing and thawing processes often result in a significant loss of sperm motility, viability and nuclear integrity. The destructive effects of cryopreservation are significantly exacerbated in samples exhibiting low sperm number and poor morphological characteristics. Recent research into infertility has focused on the correlation between excessive oxidation and subfertility, in particular radical induced lipid peroxidation within the phospholipid bilayer of the spermatozoon plasma membrane and the promotion of cellular damage as a result of antioxidant insufficiency. The aim of this study was to evaluate the effect of …

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Between The Red Tent And The Red Haze : Representations Of Perimenopause, Sheena Maureen Mcchlery Jan 2005

Between The Red Tent And The Red Haze : Representations Of Perimenopause, Sheena Maureen Mcchlery

Theses : Honours

Perimenopause is a relatively new word in our language. It is found in a variety of texts, from medical literature to popular literature and the Internet. In this thesis, I explore some current representations of perimenopause. To do so, I utilise feminist analyses of representations of premenstrual syndrome and menopause. A feminist theoretical framework guides my methodology and organisation and interpretation of data. My methodology includes an extensive literature review of feminist theorising around premenstrual syndrome and menopause, as well as discourse analysis of textual representations of perimenopause and the use of a reflexive journal as a 'perimenopausal' woman. My …

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A Feminist Jungian Analysis Of The Representations Of Teenage Females In Films 1950s To 1970s, Lea O'Dea Jan 2005

A Feminist Jungian Analysis Of The Representations Of Teenage Females In Films 1950s To 1970s, Lea O'Dea

Theses : Honours

This thesis is framed within the broad study of film theory and analysis. It is my research into the representations of teenage females in mass media films made and released in the USA and Australia in the years before and after the Sexual Revolution of the 1960s and Women's Liberation Movement that began in the 1970s. This work is significant primarily in that it is an analysis specifically of teenage females who feature as lead characters in films. The sample of films has been chosen because as mass media, mainstream films their distribution is indicative of their acceptance within the …

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21st Century Restructuring Of Employment In The Northeast, Amy Glasmeier Jan 2005

21st Century Restructuring Of Employment In The Northeast, Amy Glasmeier

Carsey Publications

Carsey Seminar Series

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Spending Health Care Dollars Wisely: Can Cost-Effectiveness Analysis Help?, Milton C. Weinstein Jan 2005

Spending Health Care Dollars Wisely: Can Cost-Effectiveness Analysis Help?, Milton C. Weinstein

Center for Policy Research

Are we getting the most health improvement possible for our money. In other words, are all the things that we do in medicine really worth it? That is where cost-effectiveness comes in. As a nation, we have been unwilling, at least publicly, to look explicitly at the value, in terms of improved health outcome, that we get for our health care dollars. With advances in medical technology putting unsustainable pressure on health care costs, our historical reluctance to measure value for health care may have to change. I start this brief by describing cost-effectiveness analysis as a method of determining …

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Labor Supply With Social Interactions: Econometric Estimates And Their Tax Policy Implications, Andrew Grodner, Thomas Kniesner Jan 2005

Labor Supply With Social Interactions: Econometric Estimates And Their Tax Policy Implications, Andrew Grodner, Thomas Kniesner

Center for Policy Research

Our research fleshes out econometric details of examining possible social interactions in labor supply. We look for a response of a person's hours worked to hours worked in the labor market reference group, which includes those with similar age, family structure, and location. We identify endogenous spillovers by instrumenting average hours worked in the reference group with hours worked in neighboring reference groups. Estimates of the canonical labor supply model indicate positive economically important spillovers for adult men. The estimated total wage elasticity of labor supply is 0.22, where 0.08 is the exogenous wage change effect and 0.14 is the …

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Analysis Of The Impact Of A Social Norms Campaign On The Alcohol Use Of Undergraduate Students At A Public, Urban University, Amanda B. Wattenmaker Jan 2005

Analysis Of The Impact Of A Social Norms Campaign On The Alcohol Use Of Undergraduate Students At A Public, Urban University, Amanda B. Wattenmaker

Theses and Dissertations

Purpose: To conduct a secondary analysis of survey data collected at a large, urban university assessing for change in students' alcohol use perceptions and behaviors between 2002 and 2004. After the baseline data collection in 2002, the campus launched an intensive media intervention to normalize low-risk drinking. Simultaneously, the campus shifted from being a primarily commuter to primarily residential. Methods: This cross-sectional analysis used data collected from students in randomly selected undergraduate classes in February 2002 (n= 662) and 2004 (n=1334). The survey instrument used was the National College Health Assessment. Variables were categorized as demographic, alcohol perception, and alcohol …

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Characterization Of The Zona Incerta, Heather Joyce Green Jan 2005

Characterization Of The Zona Incerta, Heather Joyce Green

Theses and Dissertations

Parkinson's Disease affects more than 1 million people in the United States with 60,000 new cases being diagnosed each year. Currently, there is no cure for Parkinson's Disease, but there are several treatment options available. Currently the most popular surgical option is Deep Brain Stimulation. Microelectrode recording helps identify nuclei as the microelectrode passes through them. While the firing frequencies of the target nuclei are well defined, other nuclei are not. This study will attempt to characterize the Zona Incerta, which is the structure directly above the Subthalamic Nucleus, a target nucleus. Characterization of the firing frequency of the Zona …

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An Undergraduate Theatre History Course Design Utilizing Problem-Based Learning, Mary Alice Blackwell Jan 2005

An Undergraduate Theatre History Course Design Utilizing Problem-Based Learning, Mary Alice Blackwell

Theses and Dissertations

This thesis was written to provide an alternative teaching model for an undergraduate theatre history class. The course design, utilizing the Problem-Based Learning educational model, aims to create a student-centered, experiential theatre history class. The first section explores the history and evolution of the theatre discipline in academia. These chapters examine the expansion and transformation of the theatre curriculum within the discipline and higher education. The second part examines the history and the methodologies of Problem-Based Learning. Based on the philosophy of educator John Dewey, PBL is considered to be a non-traditional method of teaching and learning that encourages the …

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Free Osteoporosis Prevention Seminar For Women Sept. 15, Deborah Purnell Jan 2005

Free Osteoporosis Prevention Seminar For Women Sept. 15, Deborah Purnell

University of Mississippi News

OXFORD, Miss. - A free osteoporosis prevention seminar for women in north Mississippi is scheduled for Thursday, Sept. 15, at the University of Mississippi.

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Incorporating Literature Into A Health Law Curriculum, Stacey A. Tovino Jan 2005

Incorporating Literature Into A Health Law Curriculum, Stacey A. Tovino

Faculty Articles

Literature has had a long relationship with medicine through literary images of disease, literary images of physicians and other healers, works of literature by physician-writers, and the use of literature as a method of active or passive healing. Literature also has had a long relationship with the law through literary images of various legal processes, lawyers, and judges, works of literature by lawyer-writers, and the use of literature as therapy. How can the field of law and literature inform the study of health law? And how can the field of literature and medicine help the field of law and literature …

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Erisa: State Regulation Of Insured Plans After Davila, Donald T. Bogan Jan 2005

Erisa: State Regulation Of Insured Plans After Davila, Donald T. Bogan

Faculty Articles

No abstract provided.

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Above Contempt?: Regulating Government Overreaching In Terrorism Cases, Peter Margulies Jan 2005

Above Contempt?: Regulating Government Overreaching In Terrorism Cases, Peter Margulies

Law Faculty Scholarship

Prosecutors face the continual temptation to overreach in decisions about the control of information. At each phase of a criminal proceeding, from investigation through trial, prosecutors make crucial decisions about information to disclose and highlight with courts, juries, and the public. In ordinary times, courts, defense counsel, the media, and internal sources of oversight can place some constraints, however tenuous, on the prosecutor’s efforts to monopolize the management of information. However, external events, such as the attacks of September 11, 2001, can weaken these constraints, producing alarming spikes in prosecutorial power.

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Evaluation Of Initial Implants For Finishing Steers, Jeffrey D. Folmer, Travis B. Farran, Galen E. Erickson, Terry J. Klopfenstein, Chris D. Reinhardt, Bill D. Dicke, Jim S. Drouillard Jan 2005

Evaluation Of Initial Implants For Finishing Steers, Jeffrey D. Folmer, Travis B. Farran, Galen E. Erickson, Terry J. Klopfenstein, Chris D. Reinhardt, Bill D. Dicke, Jim S. Drouillard

Nebraska Beef Cattle Reports

A commercial feedlot experiment utilizing 12 pens and 1038 steers evaluated initial implant strategies for feedlot steers. Steers were administered either Revalor-IS® or Synovex S® at initial processing. Both treatment groups received Revalor-S® as a terminal implant. Revalor-IS® as an initial implant improved hot carcass weight and carcass adjusted final weight; however, there was no effect on any other measure of performance or carcass characteristics. Selling steers on a carcass merit basis resulted in a similar return per head for both implant strategies. Reduced-dose combination implants may improve hot carcass weight and carcass adjusted final weight with no impact on …

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Annotated Legal Bibliography On Gender Jan 2005

Annotated Legal Bibliography On Gender

Cardozo Journal of Equal Rights & Social Justice

No abstract provided.

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The Political Science Of Hormone Folklore, Rebecca M. Young Jan 2005

The Political Science Of Hormone Folklore, Rebecca M. Young

Cardozo Journal of Equal Rights & Social Justice

No abstract provided.

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Not Playing Around: The Chilling Power Of The Federal Trademark Dilution Act Of 1995, Julie Zando-Dennis Jan 2005

Not Playing Around: The Chilling Power Of The Federal Trademark Dilution Act Of 1995, Julie Zando-Dennis

Cardozo Journal of Equal Rights & Social Justice

The Federal Trademark Dilution Act of 1995 (FTDA) has become a powerful tool for corporations to suppress criticism and parody, undermining free speech by allowing broad claims of trademark dilution without requiring proof of consumer confusion. The note argues that the FTDA’s provisions against dilution, including blurring and tarnishment, disproportionately favor corporate interests over First Amendment rights, particularly in cases involving parody and satire. Courts have inconsistently applied the law, with some circuits offering protections for parody while others prioritize trademark protection, creating uncertainty and chilling artistic and activist expression. The note advocates for reform to balance trademark rights with …

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Check Only One: M/F/Other, Julie Shapiro Jan 2005

Check Only One: M/F/Other, Julie Shapiro

Cardozo Journal of Equal Rights & Social Justice

The article critiques the assumption that individuals can be neatly categorized into male and female, arguing that this binary framework is increasingly problematic. It highlights how this assumption underpins debates about gender differences in innate abilities, such as those raised by Lawrence Summers, and contends that without clear, universally accepted definitions of "male" and "female," such generalizations lack coherence. The analysis emphasizes the legal and social complexities of gender categorization, particularly in light of evolving understandings of intersex and transgender identities.

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David Reimer's Legacy: Limiting Parental Discretion, Hazel Glenn Beh, Milton Diamond Jan 2005

David Reimer's Legacy: Limiting Parental Discretion, Hazel Glenn Beh, Milton Diamond

Cardozo Journal of Equal Rights & Social Justice

The article argues that parents should not have unilateral authority to consent to surgeries aimed at normalizing intersex children's genitalia. It emphasizes that such decisions should be deferred until the child can make informed choices, highlighting the long-term psychological and physical risks associated with early surgeries.

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Hacking The Gender Binary Myth: Recognizing Fundamental Rights For The Intersexed, Sara R. Benson Jan 2005

Hacking The Gender Binary Myth: Recognizing Fundamental Rights For The Intersexed, Sara R. Benson

Cardozo Journal of Equal Rights & Social Justice

The article argues that current medical practices allowing parents and doctors to assign a physical sex to intersex children through surgery violate the child's fundamental rights to bodily integrity, personality, gender identity, and sexuality. These rights, while not yet fully defined in jurisprudence, provide a framework for protecting individuals from unwarranted governmental and medical intrusion. The article advocates for delaying such decisions until the child can consent, drawing on the Colombian Constitutional Court's recognition of a child's right to develop their gender identity. It also highlights the broader implications for transgender rights and challenges societal gender binaries.

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Outside The Law: Intersex, Medicine And The Discourse Of Rights, Jo Bird Jan 2005

Outside The Law: Intersex, Medicine And The Discourse Of Rights, Jo Bird

Cardozo Journal of Equal Rights & Social Justice

The article argues that the legal system perpetuates the erasure of intersex individuals by constructing intersex as a medical rather than a legal issue, leading to human rights violations. It contends that the law requires individuals to fit into a binary sex classification to be recognized as fully human, thereby denying intersex people legal visibility and protection. The article advocates for the recognition of intersex as a legal category to address the systemic discrimination and violence intersex individuals face, particularly in medical practices.

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Cutting It: Surgical Interventions And The Sexing Of Children, Marie Fox, Michael Thomson Jan 2005

Cutting It: Surgical Interventions And The Sexing Of Children, Marie Fox, Michael Thomson

Cardozo Journal of Equal Rights & Social Justice

The article critiques the normalization of non-consensual surgical interventions on children, particularly focusing on male circumcision and intersex surgeries, arguing that these practices are rooted in cultural and gender norms rather than medical necessity. It challenges the legal and ethical frameworks that allow such surgeries, emphasizing the need for informed consent and stricter regulations.

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Distracted Attentions: Intersexuality And Human Rights Protections, Morgan Holmes Jan 2005

Distracted Attentions: Intersexuality And Human Rights Protections, Morgan Holmes

Cardozo Journal of Equal Rights & Social Justice

The article argues that the medicalization of intersex conditions, often justified under an "emergency" rationale, undermines the autonomy and human rights of intersex individuals, particularly children. It critiques the framing of intersex as a medical emergency, which allows clinicians to bypass informed consent and prioritize the interests of families and medical professionals over those of the intersex individual. The article advocates for a shift in approach, emphasizing human rights protections and the need to respect the autonomy of intersex persons.

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From The Hospital To The Courtroom: A Statutory Proposal For Recognizing And Protecting The Legal Rights Of Intersex Children, Erin Lloyd Jan 2005

From The Hospital To The Courtroom: A Statutory Proposal For Recognizing And Protecting The Legal Rights Of Intersex Children, Erin Lloyd

Cardozo Journal of Equal Rights & Social Justice

The article advocates for stronger legal protections for intersex children against unnecessary and harmful medical interventions, emphasizing the need for informed consent and judicial oversight to safeguard their rights and well-being.

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Engendering Sex: Birth Certificates, Biology And The Body In Anglo American Law, Saru Matambanadzo Jan 2005

Engendering Sex: Birth Certificates, Biology And The Body In Anglo American Law, Saru Matambanadzo

Cardozo Journal of Equal Rights & Social Justice

The article critically examines the legal determination of sex, particularly for transgender individuals, arguing that current systems relying on rigid biological definitions fail to account for the complexity of gender identity. It advocates for a shift towards recognizing "lived gender," which integrates biology, culture, psychology, and social interactions to create a more inclusive and accurate legal framework. This approach challenges traditional legal and medical constructs that have historically marginalized transgender individuals and calls for legal reform to better reflect individual experiences and promote inclusivity.

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Out Of The O.R. And Into The Streets: Exploring The Impact Of Intersex Media Activism, Sharon E. Preves Jan 2005

Out Of The O.R. And Into The Streets: Exploring The Impact Of Intersex Media Activism, Sharon E. Preves

Cardozo Journal of Equal Rights & Social Justice

Babies are born intersexed, with ambiguous genitalia or other reproductive anatomical features, every day. Physical sexual ambiguity occurs frequently, affecting approximately one in 2000 births. Most infants born intersexed are surgically and hormonally altered to reflect the sexual anatomy associated with "standard" female or male sex assignment. This article explores the mobilization and methods of intersex individuals and their allies to destigmatize intersexuality and to alter the medical treatment they receive. I explore the intersex movement's use of mass media as a strategic activist tool and the implications of this mobilization for cultural and medical reform, arguing that media attention …

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