Digital Commons Network^™

Inhibitors Of Protein Kinase Signaling Pathways: Emerging Therapies For Cardiovascular Disease, Thomas Force, Keisuke Kuida, Mark Namchuk, Keykavous Parang, John M. Kyriakis

Biomedical and Pharmaceutical Sciences Faculty Publications

Protein kinases are enzymes that covalently modify proteins by attaching phosphate groups (from ATP) to serine, threonine, and/or tyrosine residues. In so doing, the functional properties of the protein kinase’s substrates are modified. Protein kinases transduce signals from the cell membrane into the interior of the cell. Such signals include not only those arising from ligand–receptor interactions but also environmental perturbations such as when the membrane undergoes mechanical deformation (ie, cell stretch or shear stress). Ultimately, the activation of signaling pathways that use protein kinases often culminates in the reprogramming of gene expression through the direct regulation of transcription factors …

Can Congress Regulate Intrastate Endangered Species Under The Commerce Clause?, Bradford Mank

Faculty Articles and Other Publications

In Spring 2003, both the 5th Circuit and the D.C. Circuit agreed that Congress has the authority under the Commerce Clause to protect intrastate endangered species on private lands under the Endangered Species Act (ESA), but used completely opposite reasoning to reach the same result. The 5th Circuit in GDF Realty v. Norton rejected the government's argument that the economic impact of the commercial development regulated under the statute was the appropriate focus for whether the statute has a substantial effect on interstate commerce. Instead, the 5th Circuit concluded that intrastate spiders and beetles, which have no economic value, do …

Virginia Commonwealth University Graduate And Professional Programs Bulletin [2004], Virginia Commonwealth University

VCU Bulletins

Graduate and professional programs bulletin for Virginia Commonwealth University for the academic year 2004-2005. It includes information on academic regulations, degree requirements, course offerings, faculty, academic calendar, and tuition and expenses for graduate programs.

Virginia Commonwealth University Undergraduate Bulletin [2004], Virginia Commonwealth University

VCU Bulletins

Undergraduate bulletin for Virginia Commonwealth University for the academic year 2004-2005. It includes information on academic regulations, degree requirements, course offerings, faculty, academic calendar, and tuition and expenses for undergraduate programs.

Insites, 2004, Utah State University

inSites

Magazine of the Department of Landscape Architecture and Environmental Planning

A Comparative Evaluation Of The Habitat Value Of Shellfish Aquaculture Gear, Submerged Aquatic Vegetation And A Non-Vegetated Seabed, Joseph Dealteris, Brian D. Kilpatrick, Robert B. Rheault

Fisheries, Animal and Veterinary Sciences Faculty Publications

The habitat value of modified rack and bag, shellfish aquaculture gear (SAG) used for the grow-out phase of the American oyster, Crassostrea virginica, submerged aquatic vegetation (SAV), Zostera marina, and a shallow nonvegetated seabed (NVSB) was comparatively evaluated over a 1-year period in Pt. Judith Pond, a tidal estuary in Southern Rhode Island. Enclosure gear was used to sample the three ecotypes, and organisms (>5 mm) were identified, enumerated, and measured to the nearest millimeter. Abundances of marine organisms and species diversity indices were used as measures of the habitat value of these ecotypes within each season. Environmental …

Natural History And Sexual Dimorphism Of The Eastern Hellbender, Cryptobranchus A. Alleganiensis, Robert Makowsky

Theses, Dissertations and Capstones

The Eastern Hellbender’s natural history and morphology was examined. Field studies were done to examine the efficacy of different techniques (focusing on capturing larva) and diet analysis. Lab studies were done to determine if any sexual dimorphism exists in hellbenders using simple measurements (and ratios) and if this dimorphism could be used to reliably determine gender. Field studies were inconclusive due to the inability to find a reliable sample because of record rainfall. Lab studies revealed that a dimorphism does exist for one ratio (TG/TL, P=.048) and for several measurements. These measurements alone were not applicable for determining gender. …

Protecting Society From Patently Offensive Inventions: The Risk Of Reviving The Moral Utility Doctrine, Benjamin D. Enerson

Cornell Law Review

No abstract provided.

Who's Your Daddy?: An Analysis Of Illinois' Law Of Parentage And The Meaning Of Parenthood, Steven N. Peskind

Loyola University Chicago Law Journal

No abstract provided.

2004 South Dakota Beef Report, Department Of Animal And Range Sciences, South Dakota State University, Agricultural Experiment Station, South Dakota State University, Cooperative Extension Service, South Dakota State University

South Dakota Beef Report, 2004

This is the 2004 South Dakota Beef Report. The articles published in this report summarize many of the beef cattle research activities conducted at South Dakota State University during 2004. The articles in this report have many levels of application. Some information has immediate application for your farm, ranch, or agribusiness. The articles include information on nutrition, feed management, reproductive management, health, growth and development, and economics of the cattle and beef industry in South Dakota.

Creation: The Foundational Importance Of Scripture As Revelation, Norman R. Gulley

Journal of the Adventist Theological Society

No abstract provided.

Glycolytic And Gluconeogenic Growth Of Escherichia Coli O157:H7 (Edl933) And E. Coli K-12 (Mg1655) In The Mouse Intestine, Regina L. Miranda, Tyrrell Conway, Mary P. Leatham, Dong Eun Chang, Wendy E. Norris, James H. Allen, Sarah J. Stevenson, David C. Laux, Paul S. Cohen

Cell and Molecular Biology Faculty Publications

Escherichia coli EDL933, an O157:H7 strain, is known to colonize the streptomycin-treated CD-1 mouse intestine by growing in intestinal mucus (E. A. Wadolkowski, J. A. Burris, and A. D. O'Brien, Infect. Immun. 58:2438-2445, 1990), but what nutrients and metabolic pathways are employed during colonization has not been determined. In this study, when the wild-type EDL933 strain was fed to mice along with an EDL933 ΔppsA ΔpckA mutant, which is unable to utilize tricarboxylic acid cycle intermediates and gluconeogenic substrates for growth, both strains colonized the mouse intestine equally well. Therefore, EDL933 utilizes a glycolytic substrate(s) for both …

North Dakota Supreme Court Review

North Dakota Law Review

No abstract provided.

Difficulties In Recognizing And Treating Depression In The Elderly : Implications For Counselors, Kristin A. Schloemer

Graduate Research Papers

Diagnosing elderly depression is a difficult, overlooked process. Many elderly seek out family physicians, but few visit mental healthcare professionals (Lyness et al., 1997; Sable & Dunn, 2002). When assessing elderly depression, it is important for counselors to be aware of symptoms, ensuring correct treatment.

According to Friedrich ( 1999), it is difficult for healthcare professionals, including counselors, to diagnose depression in the elderly. As elderly may not display traditional depressive symptoms, it is necessary to distinguish between depression, bereavement, and illness, all common in late life. Once depression has been diagnosed, treatments including: medication, psychotherapy, or perhaps the most …

Demographics And The Ecological Role Of The Channel Catfish (Ictalurus Punctatus) In Commercially Exploited And Unexploited Reaches Of The Wabash River With Implications For The Flathead Catfish (Pylodictis Olivaris), Robert Colombo

Faculty Research & Creative Activity

Catfish are a major component of the Wabash River fish assemblage and are commercially fished below river kilometer (Rkm) 500. From Rkm 322 through 499 the commercial fishery is subjected only to Indiana fishing regulations. In this reach of river, there is a 254-mm minimum total length limit on both sport and commercially harvested catfish. Below RM 322, the Wabash River forms the state boundary of Indiana and Illinois. In this region of river there are two different length limits on commercially harvested catfish with Indiana having a 254-mm length limit and Illinois having a 381-mm length limit. There is …

2004 Nebraska Swine Report, Duane E. Reese

University of Nebraska-Lincoln Extension: Historical Materials

This publications was prepared by the staff in Animal Science and cooperating Departments for use in Extension, Teaching and Research programs. It deals with the results that were done in reproduction, breeding, health, genetics, nutrition, economics and housing of swine.

Using Wildlife As Receptor Species: A Landscape, Karen F. Gaines, Dwayne E. Porter, Susan A. Dyer, Gary R. Wein, John E. Pinder Iii, I. Lehr Brisbin Jr.

Faculty Research & Creative Activity

To assist risk assessors at the Department of Energy’s Savannah River Site (SRS), a Geographic Information System (GIS) application was developed to provide relevant information about specific receptor species of resident wildlife that can be used for ecological risk assessment. Information was obtained from an extensive literature review of publications and reports on vertebrate- and contaminant- related research since 1954 and linked to a GIS. Although this GIS is a useful tool for risk assessors because the data quality is high, it does not describe the species’ site-wide spatial distribution or life history, which may be crucial when developing a …

Brown-Bagging It: Engaging Students In Lecture, Paul V. Switzer

Faculty Research & Creative Activity

No abstract provided.

Renesting Decisions And Annual Fecundity Of Female Dickcissels (Spiza Americana) In Illinois, Jeffery Walk, Kevin Wentworth, Eric Kershner, Eric Bollinger, Richard Warner

Faculty Research & Creative Activity

T.-Renesting decisions and annual fecundity are crucial for interpreting other demographic information, yet are infrequently reported. We used radiotelemetry to monitor female Dickcissels (Spiza americana) throughout the 1999 and 2000 breeding seasons in south- eastern Illinois. Overall fecundity (regardless of whether females remained in the study area throughout the breeding season) was 0.61 ? 0.13 female fledglings per year. Of females that re- mained within the study area, 94% fledged young (1.25 ? 0.15 female fledglings per year). Most females (62%) that experienced nest failure emigrated from the study area (moved >10 km) in 2.8 ? 0.6 days; others (36%) …

Systematic And Comparative Anatomy Of Maxillarieae (Orchidaceae), Sans Oncidiinae, William Stern, Walter Judd, Barbara Carlsward

Faculty Research & Creative Activity

On the basis of floral and vegetative morphology, 63 tropical American genera have been recognized within Maxillarieae. We were able to examine anatomical material of all subtribes, excluding Oncidiinae. Stegmata with conical silica bodies occur in leaves and stems of all subtribes excluding Ornithocephalinae, and pericyclic stegmata found in roots are characteristic of Lycastinae. Lycastinae and Maxillariinae are characterized by foliar glands, foliar fibre bundles and tilosomes. Endodermal cells are U-thickened in most Zygopetalinae; O-thickened in most Lycastinae, Ornithocephalinae and Telipogoninae; variously thickened in Maxillariinae; and thin-walled in Cryptarrhena lunata. Water-storage cells varied from thin-walled to variously banded throughout Maxillarieae. …

Enhancing The Learning And Retention Of Biblical Languages For Adult Students, Marykate Morse

Faculty Publications - Portland Seminary

Finding ways to reduce students’ anxiety and maximize the value of learning Greek and Hebrew is a continual challenge for biblical language teachers. Some language teachers use technology tools such as web sites or CDs with audio lessons to improve the experience. Though these tools are helpful, this paper explores the value gained from understanding first how students learn and then how technology tools best support that learning. Developments in cognitive psychology and neuroscience offer many insights concerning adult learning and retention. After a presentation of key insights, several ideas are suggested for enhancing the learning and retention experience of …

University Of Southern Maine Undergraduate Catalog 2004-2005, University Of Southern Maine

Course Catalogs

No abstract provided.

A Lego Model Of The Modularity Of The Mind, Steven J. Scher

Faculty Research and Creative Activity

In this paper I propose that the dominant form of evolutionary psychology (which I term “cognitive adaptationism”) can be improved by adopting an alternative version of the concept of mental modularity. I suggest a metaphor of mental modules as Lego blocks. The Lego blocks represent a relatively small set of elementary operations that the mind/brain can carry out. These Lego blocks are repeatedly assembled in different ways to execute a wide variety of different functions. These repeated assemblies correspond more closely to the things that cognitive adaptationists have asserted are modules. Arguments in favor of the Lego model include the …

Volume 10, Number 1: February/March 2004, Suzanne Zack

UConn Libraries Newsletter

No abstract provided.

Recent Developments, Florida State University Law Review

Florida State University Law Review

No abstract provided.

Characterization Of Biological Types Of Cattle (Cycle Vi): Carcass, Yield, And Longissimus Palatability Traits, T. L. Wheeler, L. V. Cundiff, S. D. Shackelford, M. Koohmaraie

Roman L. Hruska U.S. Meat Animal Research Center: Reports

Carcass (n = 568) and longissimus thoracis palatability (n = 460) traits from F₁ steers obtained from mating Hereford (H), Angus (A), and U.S. Meat Animal Research Center (U.S. Meat Animal Research Center) III cows to H, A, Norwegian Red (NR), Swedish Red and White (RW), Friesian (F), or Wagyu (W) sires were compared. Data were adjusted to constant age (471 d), carcass weight (356 kg), fat thickness (1.0 cm), percentage of fat trim (24%), and marbling (Small35) end points. For Warner-Bratzler shear force and trained sensory panel traits, data were obtained on longissimus thoracis steaks stored at 2°C …

Breed Comparisons Of Weight, Weight Adjusted For Condition Score, Height, And Condition Score Of Beef Cows, J. A. Arango, L. V. Cundiff, L. D. Van Vleck

Roman L. Hruska U.S. Meat Animal Research Center: Reports

Breeds were compared for differences in BW (n = 56,731), heights (n = 51,407) and body condition scores (BCS, n = 56,371) of 2- to 8-yr-old cows from four cycles of the Germplasm Evaluation (GPE) Program at the U. S. Meat Animal Research Center (U.S. Meat Animal Research Center). Angus, Hereford, and topcross cows from 22 breeds of sires were produced. The mixed model for repeated measures of BW, height, and BCS included random additive genetic and permanent environmental effects of the cow. Differences among crosses were significant for all traits. In general, BW, …

Apoptosis And Porcine Reproductive And Respiratory Syndrome Virus, Laura C. Miller, James M. Fox

Roman L. Hruska U.S. Meat Animal Research Center: Reports

Despite numerous studies examining the possible induction of apoptosis in porcine reproductive and respiratory syndrome virus (PRRSV)-infected cells, it remains unclear if PRRSV infection results in direct apoptotic induction. There is clear evidence that apoptotic cells are present in tissues from PRRSV-infected pigs. However, many of these studies have failed to show that the apoptotic cells are infected with PRRSV. This has led some investigators to propose that ‘‘bystander’’ cells, not infected cells, become apoptotic during PRRSV infection by a yet undetermined mechanism. Studies examining the induction of the apoptotic gene expression response to PRRSV infection are needed to determine …

Factors Regulating Lamb Longissimus Tenderness Are Affected By Age At Slaughter, E. Veiseth, S. D. Shackelford, T. L. Wheeler, M. Koohmaraie

Roman L. Hruska U.S. Meat Animal Research Center: Reports

The objective of this experiment was to determine age-related changes in collagen concentration, sarcomere length, calpain (μ- and m-) and calpastatin activities, postmortem proteolysis and Warner–Bratzler shear force (WBSF) in ovine longissimus thoracis et lumborum. Rambouillet lambs were slaughtered at 2, 4, 6, 8 and 10 months of age and samples of longissimus were collected at 0, 2 and 10 days postmortem. Collagen concentration and sarcomere lengths were determined from the cores used for WBSF measurements and reflected changes in the background toughness. Longissimus collagen concentration did not change (P > 0.05) due to lamb age. Sarcomere lengths …

Eugenol Stimulates Lactate Accumulation Yet Inhibits Volatile Fatty Acid Production And Eliminates Coliform Bacteria In Cattle And Swine Waste, V. H. Barel, D. L. Miller

Roman L. Hruska U.S. Meat Animal Research Center: Reports

Aim: To determine how eugenol affects fermentation parameters and faecal coliforms in cattle and swine waste slurries stored anaerobically.

Methods and Results: Waste slurries (faeces : urine : water, 50 : 35 : 15) were blended with and without additives and aliquoted to triplicate 1-l flasks. Faecal coliforms were eliminated in cattle and swine waste slurries within 1 or 2 days with additions of eugenol at 10·05 mM (0·15%) and 16·75 mM (0·25%). At these concentrations volatile fatty acids (VFA) were reduced ca 70 and 50% in cattle and swine waste, respectively, over 6–8 weeks. Additionally, in cattle waste, eugenol …