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2003

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Semantic Role Parsing: Adding Semantic Structure To Unstructured Text, Sameer Pradhan, K. Hacioglu, W. Ward, James H. Martin, D. Jurafsky Jan 2003

Semantic Role Parsing: Adding Semantic Structure To Unstructured Text, Sameer Pradhan, K. Hacioglu, W. Ward, James H. Martin, D. Jurafsky

Psychological Science Faculty Research & Creative Works

There is an ever-growing need to add structure in the form of semantic markup to the huge amounts of unstructured text data now available. We present the technique of shallow semantic parsing, the process of assigning a simple WHO did WHAT to WHOM, etc., structure to sentences in text, as a useful tool in achieving this goal. We formulate the semantic parsing problem as a classification problem using support vector machines. Using a hand-labeled training set and a set of features drawn from earlier work together with some feature enhancements, we demonstrate a system that performs better than all other …

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Prostate Cancer: Some Clinical And Scientific Dilemmas., Paul D. Abel, El-Nasir Lalani Jan 2003

Prostate Cancer: Some Clinical And Scientific Dilemmas., Paul D. Abel, El-Nasir Lalani

Department of Pathology and Laboratory Medicine

No abstract provided.

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Use Of Intravenous Anti-D In Patients With Refractory And Relapsed Immune Thrombocytopenic Purpura, R. Sajid, Salman Adil, Z. Fadoo, S. Sabir, Mohammad Khurshid Jan 2003

Use Of Intravenous Anti-D In Patients With Refractory And Relapsed Immune Thrombocytopenic Purpura, R. Sajid, Salman Adil, Z. Fadoo, S. Sabir, Mohammad Khurshid

Department of Pathology and Laboratory Medicine

Objective: To determine the response to IV anti-D and its comparison with splenectomy as second line therapy in refractory and relapsed cases of ITP, in the Aga Khan University Hospital, Karachi.
Methods: A total of 23 patients with chronic ITP were treated with either anti-D or splenectomy as second line treatment. The patients were assessed for time to achieve a response to second line treatment, duration ofresponse and adverse events.
Results: There were 12 patients in the anti-D group and 11 in the splenectomy group. The mean platelet count at presentation was 9,000/cumm. The mean age was 8.9 …

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Fludarabine Induced Immune Thrombocytopenia In A Patient With Cd5 Positive B Cell Chronic Lymphocytic Leukemia, M. Usman, Salman Adil, R. Sajid, Mohammad Khurshid Jan 2003

Fludarabine Induced Immune Thrombocytopenia In A Patient With Cd5 Positive B Cell Chronic Lymphocytic Leukemia, M. Usman, Salman Adil, R. Sajid, Mohammad Khurshid

Department of Pathology and Laboratory Medicine

Fludarabine is a purine nucleoside analogue, which inhibits DNA synthesis by inhibiting DNA polymerase and ribonucleoside reductase.1 It affects both dividing and non- dividing cells.2 Fludarabine possesses proven efficacy in the treatment of a variety of indolent B cell lymphoproliferative disorders including chronic lymphocytic leukemia3, low-grade non-Hodgkin's lymphoma4 and Waldenstrom macroglobulinemia.5 It is also a part of conditioning regimes in non-myeloablative bone marrow transplantation.6 The common side effects include myelosuppression, immunosuppression, and neurologic toxicity.7 The rare side effects are immune mediated hemolytic anemia8 and thrombocytopenia.9 Here we describe a case of a middle-aged lady who was diagnosed as B cell …

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Cyclosporin Induced Fatal Rhabdomyolysis In A Young Patient With Acquired Aplastic Anemia: A Case Report, M. Usman, S. N. Adil, G. N. Kakepoto, Mohammad Khurshid Jan 2003

Cyclosporin Induced Fatal Rhabdomyolysis In A Young Patient With Acquired Aplastic Anemia: A Case Report, M. Usman, S. N. Adil, G. N. Kakepoto, Mohammad Khurshid

Department of Pathology and Laboratory Medicine

Cyclosporin is used as an immunosuppressive agent in the management of a variety of autoimmune disorders1 and in patients of organ transplant to suppress host immunity and prevent rejection.2 It is now well established that acquired aplastic anemia is secondary to immune mediated destruction of stem cells in the bone marrow3 and hence Cyclosporin is used as a first line immunosuppressive drug alone or in combination with anti lymphocyte globulin in the management of aplastic anemia.1 Rhabdomyolysis is a rare side effect of Cyclosporin.4 Here we describe a case of fatal rhabdomyolysis in a young patient who received cyclosporin for …

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Chromosomal Abnormalities As A Cause Of Recurrent Abortions: A Hospital Experience, M. Azim, A.H. Khan, Z.L. Khilji, J.A. Pal, Mohammad Khurshid Jan 2003

Chromosomal Abnormalities As A Cause Of Recurrent Abortions: A Hospital Experience, M. Azim, A.H. Khan, Z.L. Khilji, J.A. Pal, Mohammad Khurshid

Department of Pathology and Laboratory Medicine

Objective: To analyze the chromosomal abnormalities in couples with history of recurrent abortions.
Design: Retrospective study.
Setting: Cytogenetic section, Department of Pathology at the Aga Khan University Hospital. Karachi, Pakistan. Patients: Three hundred couples with history of recurrent abortions. Main outcome measure: Structural chromosomal abnormalities in carrier couples.
Results: G-banded chromosomes were analyzed from both partners of 300 couples who had had two or more spontaneous abortions. Sixteen (5.3%) couples showed a chromosomal aberration in one of the partners. Seven translocations, 5 inversions, 2 deletions and 2 sex chromosomal abnormalities were identified. There was an increase in …

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Perturbative And Nonperturbative Calculations Of Electron-Hydrogen Ionization, Stephenie J. Jones, Don H. Madison, Mark D. Baertschy Jan 2003

Perturbative And Nonperturbative Calculations Of Electron-Hydrogen Ionization, Stephenie J. Jones, Don H. Madison, Mark D. Baertschy

Physics Faculty Research & Creative Works

We compare calculations of the fully differential cross section for ionization of atomic hydrogen by electron impact using two different theories-the perturbative CDW-EIS (continuum distorted wave with eikonal initial state) approximation and the nonperturbative ECS (exterior complex scaling) method. For this comparison, we chose an impact energy of 54.4 eV, since this is near the lowest energy that our perturbative approach would be applicable and near the highest energy that can be tackled by the ECS method with our present computational resources. For the case of equal-energy outgoing electrons investigated here, the two theories predict nearly identical results except that …

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Brane Factories, Eun-Joo Ahn, Marco Cavaglia, Angela V. Olinto Jan 2003

Brane Factories, Eun-Joo Ahn, Marco Cavaglia, Angela V. Olinto

Physics Faculty Research & Creative Works

We propose that higher-dimensional extended objects (p-branes) are created by super-Planckian scattering processes in theories with TeV scale gravity. As an example, we compute the cross section for p-brane creation in a (n + 4)-dimensional spacetime with asymmetric compactification. We find that the cross section for the formation of a brane which is wounded on a compact submanifold of size of the fundamental gravitational scale is larger than the cross section for the creation of a spherically symmetric black hole. Therefore, we predict that branes are more likely to be created than black holes in super-Planckian …

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