Digital Commons Network^™

Unh Scientists Develop New Model To Study Fire In The Brazilian Amazon, David Sims

Media Relations

No abstract provided.

Synthases, Joe Chappell, Kathleen R. Manna, Joseph P. Noel, Courtney M. Starks

Pharmaceutical Sciences Faculty Patents

Novel synthases and the corresponding nucleic acids encoding such synthases are disclosed herein. Such synthases possess an active site pocket that includes key amino acid residues that are modified to generate desired terpenoid reaction intermediates and products. Synthase modifications are designed based on, e.g., the three-dimensional coordinates of tobacco 5-epi-aristolochene synthase, with or without a substrate bound in the active site.

Copper Chelation Represses The Vascular Response To Injury, Lazar Mandinov, Anna Mandinova, Stanimir Kyurkchiev, Dobroslav Kyurkchiev, Ivan Kehayov, Vihren Kolev, Raffaella Soldi, Cinzia Bagala, Ebo D. De Muinck, Volkhard Lindner, Mark J. Post, Michael Simons

Dartmouth Scholarship

The induction of an acute inflammatory response followed by the release of polypeptide cytokines and growth factors from peripheral blood monocytes has been implicated in mediating the response to vascular injury. Because the Cu2+-binding proteins IL-1alpha and fibroblast growth factor 1 are exported into the extracellular compartment in a stress-dependent manner by using intracellular Cu2+ to facilitate the formation of S100A13 heterotetrameric complexes and these signal peptideless polypeptides have been implicated as regulators of vascular injury in vivo, we examined the ability of Cu2+ chelation to repress neointimal thickening in response to injury. We observed that the oral administration of …

Method Of Identifying And Treating Invasive Carcinomas, Xinqing Chai, Julie Chao, Lee Chao, Limei Chen

UCF Patents

Prostasin protein has been found to be a useful marker for determination of the invasiveness of and as a means to treat human carcinomas. Using RT-PCR and western blot analyses, prostasin protein and mRNA expression were found in normal human prostate epithelial cells and the human prostate cancer cell line LNCaP, but not in the highly invasive human prostate cancer cell lines DU-145 and PC-3. Imunohistochemistry studies of human prostate cancer specimens revealed a down-regulation of prostasin in high-grade tumors. Using RT-PCR and western blot analyses, prostasin protein and mRNA expression were found in a non-invasive human breast cancer cell …

Is Hp1 An Rna Detector That Functions Both In Repression And Activation?, Rebecca Kellum

Biology Faculty Publications

Heterochromatin is defined as regions of compact chromatin that persist throughout the cell cycle (Heitz, 1928). The earliest cytological observations of heterochromatin were followed by ribonucleotide labeling experiments that showed it to be transcriptionally inert relative to the more typical euchromatic regions that decondense during interphase. Genetic studies of rearrangements that place euchromatic genes next to blocks of heterochromatin also pointed out the repressive nature of heterochromatin (Grigliatti, 1991; and references therein). The discovery of the heterochromatin-enriched protein heterochromatin protein 1 (HP1) by Elgin and co-workers in the mid-1980s suggested that the distinct cytological features of this chromatin may be …

Comparing Regeneration Techniques For Afforesting Previously Farmed Bottomland Hardwood Sites In The Lower Mississippi Alluvial Valley, Usa, Brian Roy Lockhart, Bob Keeland, John Mccoy, Thomas J. Dean

Faculty Publications

A study was implemented to test site preparation methods and artificial regeneration of three oak (Quercus spp.) species on four agricultural fields in the Lower Mississippi Alluvial Valley in Louisiana, USA. Six years after establishment, few consistent differences were found in oak density between sowing acorn methods (seed drill versus broadcast seeding), autumn sowing versus spring sowing, and sowing acorns versus planting oak seedlings. Results indicated that some degree of site preparation is needed to establish oak seedlings but few differences were found between site preparation treatments. These results indicate that no one prescription for oak regeneration fits all potential …

May 26, 2003 Reporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Taylor University 2003 Commencement, Taylor University

Commencement

The program of the 2003 Annual Commencement of Taylor University, May 24, 2003

Murray Ledger And Times, May 24, 2003, Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.

The Image Of God And Human Identity: An Explanation Informed By The Two Kinds Of Righteousness, Lucas Woodford

Master of Sacred Theology Seminar Papers

For centuries discussion and debate over the image of God has engaged theologians of every tradition. What is the image of God? Of what does it consist? How does Scripture speak of this image? Does it relate to all human beings? Establishing answers and definitions to such questions is a difficult yet vitally important task. Significant to these discussions are the implications that such definitions will have upon the understanding of human identity and human existence.

Treatments on the image of God have a variety of definitions and interpretations depending on the individual theologian and their theological tradition. There are …

Cal Poly Engineering Student Takes First In State University Research Competition, Public Affairs Office

Press Releases

No abstract provided.

2003 Commencement Program, Whittier College

Commencement Programs

Whittier College's Centennial Commencement, May 23, 2003

Commencement Address: The Honorable Rosario Marin

Identifying Target Populations For Screening Or Not Screening Using Logic Regression, Holly Janes, Margaret S. Pepe, Charles Kooperberg, Polly Newcomb

UW Biostatistics Working Paper Series

Colorectal cancer remains a significant public health concern despite the fact that effective screening procedures exist and that the disease is treatable when detected at early stages. Numerous risk factors for colon cancer have been identified, but none are very predictive alone. We sought to determine whether there are certain combinations of risk factors that distinguish well between cases and controls, and that could be used to identify subjects at particularly high or low risk of the disease to target screening. Using data from the Seattle site of the Colorectal Cancer Family Registry (C-CFR), we fit logic regression models to …

Supervised Detection Of Regulatory Motifs In Dna Sequences, Sunduz Keles, Mark J. Van Der Laan, Sandrine Dudoit, Biao Xing, Michael B. Eisen

U.C. Berkeley Division of Biostatistics Working Paper Series

Identification of transcription factor binding sites (regulatory motifs) is a major interest in contemporary biology. We propose a new likelihood based method, COMODE, for identifying structural motifs in DNA sequences. Commonly used methods (e.g. MEME, Gibbs sampler) model binding sites as families of sequences described by a position weight matrix (PWM) and identify PWMs that maximize the likelihood of observed sequence data under a simple multinomial mixture model. This model assumes that the positions of the PWM correspond to independent multinomial distributions with four cell probabilities. We address supervising the search for DNA binding sites using the information derived from …

Three Professors Awarded University's Highest Teaching Honor, Public Affairs Office

Press Releases

No abstract provided.

Special Olympics Participation In School Age Children With Mental Retardation And Its Effects On Self-Esteem, Megan Lococo

Theses

A comprehensive review of the literature and interviews with local experts has found a paucity of research on the self-esteem of school-age children with mental retardation. Long (1995), Zic & Igric (2001) and Siperstein & Leffert (1997) found lower self-esteem in self-report measures completed by mentally retarded children and adults. However, the psychometric properties of selfesteem self-report measures have been questioned repeatedly, finding insufficient reliability and validity when applied to mentally retarded populations (Finlay & Lyons, 2001; Widaman et al., 1992). The purpose of this study is twofold; the first goal is to determine the average self-esteem for mentally retarded …

Mustang Daily, May 23, 2003

Cal Poly Student Newspaper

Student newspaper of California Polytechnic State University, San Luis Obispo, CA.

Predicting Irregularities In Population Cycles, Shandelle M. Henson, James R. Reilly, Suzanne L. Robertson, Matthew C. Schu, Eric W. D. Rozier, J. M. Cushing

Faculty Publications

Oscillating population data often exhibit cycle irregularities such as episodes of damped oscillation and abrupt changes of cycle phase. The prediction of such irregularities is of interest in applications ranging from food production to wildlife management. We use concepts from dynamical systems theory to present a model-based method for quantifying the risk of impending cycle irregularity.

Mustang Daily, May 22, 2003

Cal Poly Student Newspaper

Student newspaper of California Polytechnic State University, San Luis Obispo, CA.

Boersma, Vernon Oral History Interview: Polio Survivors In Holland, Matthew Nickel

Polio Survivors in Holland

Oral Histories conducted with Polio Survivors in Holland, Michigan in 2003.

Illinois Wesleyan Graduates 499 Seniors (Full List), Ann Aubry

Press Releases 2000-2009

No abstract provided.

Murray Ledger And Times, May 21, 2003, Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.

May 21st 2003, Hispanic News

Inland Empire Hispanic News

No abstract provided.

Ke Alaka'i, Vol. 66, No. 16 (2003-05-21), Brigham Young University Hawaii

Ke Alaka'i

No abstract provided.

Central Florida Future, Vol. 35 No. 64, May 21, 2003

Central Florida Future

With great power comes a physical explanation: Action films teach students the law of physics; Bush blocks travel to Cuba; Don't like that grade? An appeal can change it.

Interview With Bobby Plair - Oh 678, Bobby Plair, Emmett Scott High School

Winthrop University Oral History Program

This interview was conducted by Dr. George Garrison with Bobby Plair for his project on the history of Emmett Scott High School. Emmett Scott was the segregated high school for African Americans in Rock Hill, South Carolina. The school was named for Emmett Scott, a former aide to Booker T. Washington and President Woodrow Wilson. Emmett Scott was opened in 1920 and then closed in 1970 with the full integration of Rock Hill School District. Mr. Plair is an Emmett Scott Alumnus and local musician. He talks about his experiences in Emmett Scott High School during the 1940s. He also …

85th Commencement Address - What Do Novelists Know?, Wally Lamb

Commencement Addresses

No abstract provided.

Cultural Differences Of Brain Death Focus Of Lawrence University Biomedical Ethics Lecture, Lawrence University

Press Releases

Anthropologist Margaret Lock compares the concept of brain death in Japan and North America and how culture and politics have influenced its recognition and impacted organ transplantation in the final installment of Lawrence University’s 2002-2003 Edward F. Mielke Lecture Series in Biomedical Ethics.

Lock, associate professor in social studies in medicine at Montreal’s McGill University, presents “Twice Dead: Organ Transplants and the Reinvention of Death” Wednesday, May 28 at 7 p.m. in the Wriston Art Center auditorium on the Lawrence campus.

A specialist in the relationship between culture, technoscience, health and illness, Lock will examine the reasons behind widespread anxiety …

Lock And Key Micelles, George R. Newkome, Charles N. Moorefield, Gregory Baker

USF Patents

A lock unimolecular micelle includes at least one engineered acceptor specifically binding a ligand (or specifically a “key” unimolecular micelle) thereto. A key unimolecular micelle comprises a core molecule and a plurality of branches extending therefrom, at least one of the branches including a shank portion extending therefrom having a terminal moiety at an end thereof for binding to a complimentary acceptor of a lock unimolecular micelle. Together, the lock and key micelles form a unit, either irreversibly or reversibly bound wherein the lock micelles is a soluble receptor engineered to specifically bind to the specifically engineered key micelle.

A Subpixel Target Detection Algorithm For Hyperspectral Imagery, Kyungsuk Lee

Theses

The goal of this research is to develop a new algorithm for the detection of subpixel scale target materials on the hyperspectral imagery. The signal decision theory is typically to decide the existence of a target signal embedded in the random noise. This implies that the detection problem can be mathematically formalized by signal decision theory based on the statistical hypothesis test. In particular, since any target signature provided by airborne/spaceborne sensors is embedded in a structured noise such as background or clutter signatures as well as broad band unstructured noise, the problem becomes more complicated, and particularly much more …