Digital Commons Network^™

Characterisation Of A Sexual Stage-Specific Gene Encoding Orc1 Homologue In The Human Malaria Parasite Plasmodium Falciparum, J-L Li, Ls Cox

School of Biomedical Sciences

The origin recognition complex (ORC) is a multisubunit protein composed of six polypeptides that binds to replication origins and is essential for the initiation of chromosomal DNA replication. Using the Vectorette technique, we have isolated a novel gene encoding an ORC1-like protein from the human malaria parasite Plasmodium falciparum. The gene has no introns and encodes a protein (PfORC1) of 1189 amino acid residues with a predicted molecular mass of 139 kDa. PfORC1 contains all conserved sequences in the ORC1/Cdc6/Cdc18 family and displays the highest homology to the Schizosaccharomyces pombe ORC1. However, PfORC1 possesses an extensive N-terminal segment with several …

Complete Analysis Of The B‐Cell Response To A Protein Antigen, From In Vivo Germinal Centre Formation To 3‐D Modelling Of Affinity Maturation, Cl Adams, Mkl Macleod, Ej Milner-White, Et Al

School of Biomedical Sciences

Somatic hypermutation of immunoglobulin variable region genes occurs within germinal centres (GCs) and is the process responsible for affinity maturation of antibodies during an immune response. Previous studies have focused almost exclusively on the immune response to haptens, which may be unrepresentative of epitopes on protein antigens. In this study, we have exploited a model system that uses transgenic B and CD4+ T cells specific for hen egg lysozyme (HEL) and a chicken ovalbumin peptide, respectively, to investigate a tightly synchronized immune response to protein antigens of widely differing affinities, thus allowing us to track many facets of the development …

A Value Focused Thinking Approach To Software Interface In A Complex Analytical Domain, Christopher M. Mcgee

Theses and Dissertations

The intelligence community is faced with an extensive amount of data. Software programs are being developed to examine this issue of data overload and to develop solutions. The responsibility of making the final software decision lies on the analyst, therefore, the interface is the key to linking the intelligence data to the processing and results, If the interface is difficult and complex, the software will be less likely to be used. A methodology must be created which can objectively evaluate the effectiveness of the interface, This methodology will also measure the improvements in the interface's effectiveness that result when various …

Chimes: February 28, 2003, Calvin College

Chimes

Student Senate passes anti-war resolution by Will Refvem

Rangeela 2003: a festival of music, dancing, and culture by Jodi Anderson

Faculty begin sexual harassment awareness training by Laura Peterson

Student siblings come to campus by Peter Ippel

March brings films on women by Becca Morrison

Residence Life provides online housing search by Stephanie Biesheuvel

Calvin Hockey Goes National! by Ted Fackler

Calvin leaves MIAA with tarnished armor by Mike Roorda

Behind the scenes of Dialogue by Adam Petty

White snow brings blue feelings for those with SAD by Cathy Guiles

Walking in a medieval wonderland by Adam Petty

Alfalfa Disease Management, Paul Vincelli

Kentucky Alfalfa and Stored Forage Conference

Alfalfa can be a vigorous and productive forage crop for Kentucky farmers. Like all farm crops, however, alfalfa is subject to infectious diseases that can limit forage production. Managing these diseases is an important part of economical alfalfa production.

Um Breakthrough Stands The Test Of Time, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.

February 24, 2003 Reporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Paleopharmacology And Pollen: Theory, Method, And Application, Sérgio A.M. Chaves, Karl J. Reinhard

School of Natural Resources: Faculty Publications

Parasitism was a universal human condition. Because of this, people developed herbal medicines to treat parasites as part of their pharmacopoeias. We propose that it is possible to recover evidence of medicinal plants from archaeological sites and link their use to specific health conditions. This is a multidisciplinary approach that must involve at least paleoethnobotanists, archaeoparasitologists, paleopathologists, and pharmacologists.

Inca Expansion And Parasitism In The Lluta Valley: Preliminary Data, Santoro Calagero, Karl J. Reinhard, Sheila D. Vinton

School of Natural Resources: Faculty Publications

Assessing the impact of cultural change on parasitism has been a central goal in archaeoparasitology. The influence of civilization and the development of empires on parasitism has not been evaluated. Presented here is a preliminary analysis of the change in human parasitism associated with the Inca conquest of the Lluta Valley in Northern Chile. Changes in parasite prevalence are described. It can be seen that the change in life imposed on the inhabitants of the Lluta Valley by the Incas caused an increase in parasitism.

Parasite Remains In Archaeological Sites, Françoise Bouchet, Niéde Guidon, Katharina Dittmar, Stephanie Harter, Luiz F. Ferreira, Sérgio A.M. Chaves, Karl J. Reinhard, Adauto Araújo

School of Natural Resources: Faculty Publications

Organic remains can be found in many different environments. They are the most significant source for paleoparasitological studies as well as for other paleoecological reconstruction. Preserved paleoparasitological remains are found from the driest to the moistest conditions. They help us to understand past and present diseases and therefore contribute to understanding the evolution of present human sociality, biology, and behavior. In this paper, the scope of the surviving evidence will be briefly surveyed, and the great variety of ways it has been preserved in different environments will be discussed. This is done to develop to the most appropriated techniques to …

Newscast, February 21, 2003, Illinois State University, College Of Applied Science And Technology

newsCAST

Newsletter of the Illinois State University College of Applied Science and Technology

Volume 40, Number 24: February 21, 2003, University Of North Dakota

University Letter Archive

No abstract provided.

The Four Hundred Eleventh Report Of The Curricular Affairs Committee, University Of Rhode Island Faculty Senate

Faculty Senate Bills

No abstract provided.

Impact Of Ectoparasites On The Demography Of A Small Reef Fish, Rachel J. Finley, Graham E. Forrester

Natural Resources Science Faculty Publications

In marine systems, empirical studies demonstrating effects of macroparasites on host population dynamics are relatively few. We tested the effects of a copepod macroparasite infecting the gills of a small coral reef fish, the bridled goby Coryphopterus glaucofraenum. Fish that were naturally infected and uninfected were tagged as individuals and tracked in the field for 5 mo. Parasitism was associated with an increase in gill ventilation rate, and a reduction in feeding. More importantly, parasitized fish showed significantly reduced growth (by 66%) and gonad mass (by 68%) compared to uninfected fish, and parasitism increased instantaneous mortality by a factor …

Agenda And Minutes, University Of South Florida Board Of Trustees Meeting, February 20, 2003, University Of South Florida. Board Of Trustees

SACS Historical Forms and Applications

Agenda and minutes for the University of South Florida's Board of Trustees on February 20, 2003.

The Bg News February 19, 2003, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. February 19, 2003. Volume 92-Issue 26.

Ada News - 02/17/2003, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Washington University Record, February 14, 2003

Washington University Record

No abstract provided.

The Cowl - Feb 13, 2003 - Valentine's Day Special Issue

The Cowl

The Cowl - student newspaper of Providence College. February 13, 2003 - Valentine's Day Special Issue. 8 pages.

February 12, 2003, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

February 10, 2003 Reporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Washington University Record, February 7, 2003

Washington University Record

No abstract provided.

Curricular Affairs Committee Report #411, University Of Rhode Island Faculty Senate

Faculty Senate Committee Reports and Appendices

No abstract provided.

February 3, 2003 Reporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Progress Notes, Lehigh Valley Health Network

Progress Notes

No abstract provided.

Hepp Report: Infectious Diseases In Corrections, Vol. 6 No. 2, Hiv & Hepatitis Education Prison Project

Infectious Diseases in Corrections Report (IDCR)

No abstract provided.

Five-Member Gene Family Of Bartonella Quintana, Michael F. Minnick, Kate N. Sappington, Laura S. Smitherman, Siv G. E. Andersson, Olof Karlberg, James A. Carroll

Biological Sciences Faculty Publications

Bartonella quintana, the agent of trench fever and an etiologic agent of bacillary angiomatosis, has an extraordinarily high hemin requirement for growth compared to other bacterial pathogens. We previously identified the major hemin receptor of the pathogen as a 30-kDa surface protein, termed HbpA. This report describes four additional homologues that share approximately 48% amino acid sequence identity with hbpA. Three of the genes form a paralagous cluster, termed hbpCAB, whereas the other members, hbpD and hbpE, are unlinked. Secondary structure predictions and other evidence suggest that Hbp family members are beta-barrels located in the outer membrane and contain eight …

A Comprehensive Review Of The Ecological And Human Social Effects Of Artificial Feeding And Baiting Of Wildlife, L. Dunkley, M.R.L. Cattet

Canadian Cooperative Wildlife Health Centre: Newsletters and Publications

In recent years, events within Canada and the United States have drawn attention to potential negative consequences of feeding and baiting wild animals, especially enhanced transmission of infectious diseases such as bovine tuberculosis and chronic wasting disease. This report was prepared to gather available science-based information on the ecological and human social effects of artificial feeding and baiting of wildlife into one readily accessible document. The contracting agencies, Parks Canada and Saskatchewan Environment, recognize that an objective review of existing literature may help to answer questions and concerns within and outside the agencies, and help to guide subsequent decision-making concerning …

School And Mental Health Counselors: Recommendations When Working With Bosnian Refugees, Roberto Clemente

Michigan Journal of Counseling: Research, Theory and Practice

This study focused on perceptions about difficulties with acculturation for Bosnian refugees and their views on mental health counseling. It provides an overview of the Bosnian refugee dynamics in the United States of America and a description of the post-traumatic stress disorder (PTSD) as a condition faced by many refugees of war. Using a standard set of questions, two interviews were conducted with four school and mental health counselors to draw out emerging themes in counselor perceptions relating to the needs of this population. Implications and recommendations for mental health (community agencies) and school counselors are provided.

Enterobius Vermicularis: Ancient Dna From North And South American Human Coprolites, Alena M. Iñiguez, Karl J. Reinhard, Adauto Araújo, Luiz F. Ferreira, Ana Carolina P. Vicente

School of Natural Resources: Faculty Publications

A molecular paleoparasitological diagnostic approach was developed for Enterobius vermicularis. Ancient DNA was extracted from 27 coprolites from archaeological sites in Chile and USA. Enzymatic amplification of human mtDNA sequences confirmed the human origin. We designed primers specific to the E. vermicularis 5S ribosomal RNA spacer region and they allowed reproducible polymerase chain reaction identification of ancient material. We suggested that the paleoparasitological microscopic identification could accompany molecular diagnosis, which also opens the possibility of sequence analysis to understand parasite-host evolution.