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Molecular Phylogeny Of Haematoloechus Looss, 1899 (Digenea: Plagiorchiidae), With Emphasis On North American Species, Daniel R. Brooks, Virginia León-Règagnon

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Phylogenetic hypothesis of 23 populations corresponding to 18 species of the digenean Haematoloechus from America, Europe, and Africa, based on ribosomal DNA 28S partial sequences (~890 bp), is presented. Genetic divergence between the in-group and the out-groups ranged from 9.7 to 14.5% and within the in-group, from 0.9 to 12.2%. Eight most parsimonious trees 569 steps long were obtained, with a consistency index of 72%. Groups in the tree are not congruent with those in previous classification schemes of species in the genus, based on a small number of morphological characters. For this subset of Haematoloechus,/i> species, plesiomorphic hosts are …

Presidential Address: Flavor Buds And Other Delights, Robin M. Overstreet

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Presidential address at the 78th Annual Meeting, American Society of Parasitologists, August 2, 2003, Halifax, Nova Scotia, Canada, by Robin M. Overtsreet.

Superior Protection Against Malaria And Melanoma Metastases By A C-Glycoside Analogue Of The Natural Killer T Cell Ligand Α-Galactosylceramide, John Schmieg, Guangli Yang, Richard W. Franck, Moriya Tsuji

Publications and Research

α-Galactosylceramide (α-GalCer) is a glycolipid that stimulates natural killer T cells to produce both T helper (Th) 1 and Th2 cytokines. This property enables α-GalCer to ameliorate a wide variety of infectious, neoplastic, and autoimmune diseases; however, its effectiveness against any one disease is limited by the opposing activities of the induced Th1 and Th2 cytokines. Here, we report that a synthetic C-glycoside analogue of α-GalCer, α-C-galactosylceramide (α-C-GalCer), acts as natural killer T cell ligand in vivo, and stimulates an enhanced Th1-type response in mice. In two disease models requiring Th1-type responses for control, namely malaria and melanoma metastases, α-C-GalCer …

Interleukin-10 And Pathogenesis Of Murine Ocular Toxoplasmosis, Fangli Lu, Shiguang Huang, Lloyd H. Kasper

Dartmouth Scholarship

To understand the role of interleukin-10 (IL-10) in ocular toxoplasmosis, we compared C57BL/6 (B6) and BALB/c background mice lacking a functional IL-10 gene (IL-10(-/-)) and B6 transgenic mice expressing IL-10 under the control of the IL-2 promoter. Increased cellular infiltration and necrosis were observed in the eye tissue of IL-10(-/-) mice of both the B6 and BALB/c backgrounds with associated changes in the levels of cytokines in serum. In contrast, there was no evidence of necrosis in the eye tissue from IL-10 transgenic mice following parasite exposure. Our results demonstrate that IL-10 is important in the regulation of inflammation during …

Socio-Economic And Diagnostic Aspects Of Tuberculosis In Pakistan, Saba Sohail

Department of Radiology

No abstract provided.

The Role Of Monocytes In Pristane-Induced Plasmacytoma Escape, Tina L. Sumpter

All-Inclusive List of Electronic Theses and Dissertations

Multiples myelomas are untreatable neoplasias in humans, arising from terminally differentiated B cells (plasma cells). The murine pristane-induced plasmacytoma model offers a system for studying the cellular interactions involved in sustaining the growth of plasma cell tumors. In accord with this model, syngenic plasma cell tumors transplanted into the peritoneal cavity of a genetically susceptible mouse are normally cleared by the mouse's immune system. If the mouse is pretreated with pristane (2,6,10,14- tetramethylpentadecane) intraperitoneally, prior to the transplantation of the plasma cell tumor, the tumor thrives, culminating in the death of the mouse. Intraperitoneal administration of pristane results in an …

What To Compensate? Some Surprisingly Unappreciated Reasons Why The Problem Is So Hard, Leo Katz

San Diego Law Review

The aim of this Article is to get to the bottom of what makes compensation problems so hard.

Determination Of The Optimal Form Of A Dna Vaccine To Induce An Effective Immune Response Against A Murine B-Cell Lymphoma, Deepti Aurora

All-Inclusive List of Electronic Theses and Dissertations

Tumor vaccines are a promising alternative to chemotherapy for the treatment of cancer. To be effective and safe, a cancer vaccine should specifically target antigens expressed only on tumor cells. The B-cell tumor-derived Ig receptor may be considered a model tumor antigen for cancer vaccine development. Specifically the immunoglobulin idiotype (ld) encoded by the variable region genes (VH and VL) provides a target antigen. Promising results have been obtained in clinical studies of ld vaccination using ld proteins. However, ld protein is laborious and time-consuming to produce. Gene-based vaccines, on the other hand, are inexpensive and offer ease of manipulation …

Volume 41, Number 14: November 28, 2003, University Of North Dakota

University Letter Archive

No abstract provided.

Faculty Senate Meeting Minutes, 11/25/2003, P 206-256, Unm Faculty Senate

Faculty Senate Meeting Minutes, 1920 - 2013

No abstract provided.

Volume 41, Number 13: November 21, 2003, University Of North Dakota

University Letter Archive

No abstract provided.

Studies On Antibacterial Activities Of N-Thiolated Β-Lactams And Their Polymeric Nanoparticles Against Mrsa, Jeung-Yeop Shim

USF Tampa Graduate Theses and Dissertations

Methicillin-resistant Staphylococcus Aureus (MRSA) is now the most challenging bacterial pathogen affecting patients in hospitals and in care centers, and has brought on the need to develop new drugs for MRSA. This thesis centers on studies of N-thiolated β-lactams, a new family of potent antibacterial compounds that selectively inhibit the growth of methicillin-resistant Staphylococcus aureus (MRSA).

Chapter 1 describes MRSA in more detail. Chapter 2 outlines experiments on the effect of a fatty ester group (CO₂R) on the C₄-phenyl ring of N-methylthio β-lactams, expecting that attachment of long chain ester moieties might increase the hydrophobicity, …

2-Oxo-1, 4-Benzoxazine Compounds For Treatment Of Tuberculosis, Delbert Miles, Elena Goun, Suslonov Michailovich, Saleh Naser, Krasnych Pertrovna

UCF Patents

Compounds belonging to novel classes of 2-oxo-1,4-benzoxazine heterocyclic compounds and their close derivatives, are disclosed along with the surprising use property of these compounds as bacteriostatic agents for humans and non-humans against mycobacteria. These species include: 4-benzoyl-3-benzoyloxy-2-(2-oxo-2H-1,4-benzoxazin-3-yl)pyrido[2,1-c][1,4]b enzoxazin-1,5-dione; and, 2,4,6-trimethylphenyl 2-(3,4-dihydro-2-oxo-2H-1,4-benzoxazin-3-ylidene)-3-p-methoxyphenyl-3-oxo- propanoate.

November 17, 2003, James Madison University

The Breeze, 2000-2009

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

Washington University Record, November 14, 2003

Washington University Record

No abstract provided.

Comida Sin Frijoles No Es Comida: Evaluation Of A Type 2 Diabetes Education Program For Latinos, Danielle R. O'Connor

USF Tampa Graduate Theses and Dissertations

This thesis describes an internship for the Department of Anthropology that was part of the Florida Health Literacy Study (FHLS) conducted at the University of South Florida College of Public Health, Department of Community and Family Health in the spring and summer of 2003. The FHLS implemented Pfizer Inc.'s For Your Health program, a type 2 diabetes and hypertension education programs, at 14 community health clinics across the state of Florida. The internship was designed to elicit the experiences of 10 bilingual health educators about their experiences and their perceptions of the experiences of their Latino patients with type 2 …

November 10, 2003 Reporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

The Hilltop 11-7-2003, Hilltop Staff

The Hilltop: 2000 - 2010

No abstract provided.

Rotunda - Vol 83, No 10 - Nov 6, 2003, Longwood University

Rotunda

No abstract provided.

The Cowl - Vol 67 - No. 11 - Nov 6, 2003

The Cowl

The Cowl - student newspaper of Providence College. Vol 67 - No. 11 - November 6, 2003. 24 pages.

Independent- Nov. 4, 2003, Andrea Zelinski

The Independent (1988-present)

No abstract provided.

Nota Bene, November 3, 2003

Nota Bene, 2003

No abstract provided.

Predictors Of General Medical Use Among Individuals Seeking Therapy For Marital And Family Problems, Jacob D. Christenson

Theses and Dissertations

A number of studies have examined variables associated with medical use. However, most of the studies deal with samples that are not easily generalizable to other populations. In particular, no study is known to have looked at general medical use among people seeking services for marital and family problems. In this study, medical use of participants from the marriage and family therapy services at Brigham Young University Comprehensive Clinic was investigated to determine the best predictors of general medical use. Best subsets multiple linear regression showed that the best overall predictors of general medical use were anxiety and hostility.

The Collegian (2003-11-03), Sonia Mejia

UTB/TSC Archives - The Collegian [Newspaper]

Vol. 56, No. 11

Central Florida Future, Vol. 36 No. 21, November 3, 2003

Central Florida Future

Pink slipped: UCF students canned as budget cuts begin; Writing Center another victim of cash woes; Identity theft speech provides wake-up call; Blood drives still reject gay donors.

An Evaluation Of The Avian Surveillance System For West Nile Virus In Connecticut, 2000, Susan Smolenski

UCHC Graduate School Masters Theses 2003 - 2010

No abstract provided.

Kickshaws, Dave Morice

Word Ways

A collection of linguistic kickshaws.

Hsc E-News., Health Sciences Center, Stony Brook University.

HSC E-News

No abstract provided.

Assessing Animal Welfare At The Farm And Group Level: The Interplay Of Science And Values, D. Fraser

Assessment of Animal Welfare Collection

In the social debate about animal welfare we can identify three different views about how animals should be raised and how their welfare should be judged: (1) the view that animals should be raised under conditions that promote good biological functioning in the sense of health, growth and reproduction, (2) the view that animals should be raised in ways that minimise suffering and promote contentment, and (3) the view that animals should be allowed to lead relatively natural lives. When attempting to assess animal welfare, different scientists select different criteria, reflecting one or more of these value-dependent views. Even when …

Hepp Report: Infectious Diseases In Corrections, Vol. 6 No. 11, Hiv & Hepatitis Education Prison Project

Infectious Diseases in Corrections Report (IDCR)

No abstract provided.