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2003

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Pcr Analysis Of Hsv-Negative Erythema Multiforme For The Expression Of Other Herpesviruses, Mukadder Koçak, Emel Erkek, Özgül Kisa, Çakir Güney, Ahu Bi̇rol Jan 2003

Pcr Analysis Of Hsv-Negative Erythema Multiforme For The Expression Of Other Herpesviruses, Mukadder Koçak, Emel Erkek, Özgül Kisa, Çakir Güney, Ahu Bi̇rol

Turkish Journal of Medical Sciences

Background: Herpes simplex virus (HSV) is the primary herpesvirus implicated to have a causal role in erythema multiforme (EM), both in cases with an antecedent herpetic infection and in idiopathic EM. However, the association of EM with several other viral infections has been clearly documented. Objective: The aim of the present study was to investigate a hypothetical role for the remaining members of the herpesvirus family in HSV-negative cases of EM. Methods: Fresh, unfixed lesional skin biopsies from 25 patients with HSV-negative EM were studied for the presence of Epstein-Barr virus (EBV), cytomegalovirus (CMV), human herpesvirus-6 (HHV-6) and human herpesvirus-7 …

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Lipid Peroxidation, Nitrate And Nitrite Levels In Eclamptic And Intrauterine Growth Retarded Pregnancies, Hati̇ce Paşaoğlu, Nesli̇han Bukan, Gülsen Bulduk, Şevki̇ Çelen Jan 2003

Lipid Peroxidation, Nitrate And Nitrite Levels In Eclamptic And Intrauterine Growth Retarded Pregnancies, Hati̇ce Paşaoğlu, Nesli̇han Bukan, Gülsen Bulduk, Şevki̇ Çelen

Turkish Journal of Medical Sciences

In this study we investigated nitric oxide metabolites nitrate+nitrite and lipid peroxidation product (malonyldialdehyde: MDA) related to the pathogenesis of eclampsia and intrauterine growth retarded (IUGR) pregnancy. Plasma nitrate+nitrite levels were higher in the eclamptic (31.6 ± 16.7 µmol/L p < 0.001) and IUGR (24.3 ± 9.5 µmol/L p < 0.005) groups than in the control group (18.8 ± 6.9 µmol /L). Plasma MDA levels were higher in the eclamptic group (5.5 ± 2.5 nmol/ml (p < 0.05) but not significantly different in the IUGR (3.4 ± 2.4 nmol/ml p > 0.05) group than control group (3.0 ± 1.3 nmol/ml). In addition, the plasma nitrite+nitrate and MDA levels in the eclamptic group were higher than in the IUGR group (p < 0.05). These variations could play different roles in the pathogenesis of eclampsia and IUGR pregnancy.

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Lecithin:Cholesterol Acyltransferase Activity And Cholesteryl Ester Transfer Rate In Patients With Diabetes Mellitus, Melahat Di̇ri̇can, Zehra Serdar, Emre Sarandöl, Esma Sürmen Gür Jan 2003

Lecithin:Cholesterol Acyltransferase Activity And Cholesteryl Ester Transfer Rate In Patients With Diabetes Mellitus, Melahat Di̇ri̇can, Zehra Serdar, Emre Sarandöl, Esma Sürmen Gür

Turkish Journal of Medical Sciences

Several factors may be responsible for the high prevalence of atherosclerosis in diabetes mellitus, including alterations in reverse cholesterol transport. In the present study, the activity of plasma lecithin:cholesterol acyltransferase (LCAT) and the cholesteryl ester transfer rate, and concentrations of lipids and lipoproteins were measured in 11 patients with insulin-dependent diabetes mellitus (type 1), 42 patients with noninsulin-dependent diabetes mellitus (type 2) and compared with those in age-matched control groups (Control I, n = 14; and Control II, n = 29, respectively). No statistically significant differences were observed in plasma total cholesterol, triglyceride, ester cholesterol or very low density lipoprotein …

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Comparison Of Indirect Methods For Lactose Malabsorption, İsmai̇l Kurt, Mohammed Wael Abou Ghoush, Adnan Haşi̇mi̇, A. Muhi̇tti̇n Serdar, Türker Kutluay Jan 2003

Comparison Of Indirect Methods For Lactose Malabsorption, İsmai̇l Kurt, Mohammed Wael Abou Ghoush, Adnan Haşi̇mi̇, A. Muhi̇tti̇n Serdar, Türker Kutluay

Turkish Journal of Medical Sciences

Although direct determination of the lactase activity of the small intestinal mucosa is considered a "gold standard" for the diagnosis of hypolactasia leading to lactose malabsorption, less invasive and simpler indirect techniques like the "plasma glucose response test" and "breath hydrogen test" are preferred in daily practice to diagnose the disorder. The aim of this study was to compare the different indirect diagnostic methods for lactose malabsorption. The following tests were performed in 54 adults: plasma glucose response test, breath hydrogen test and urine galactose/creatinine ratio. The diagnostic variables were as follows: increased plasma glucose £ 20 mg/dl; increased exhalation …

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Subtalar Dislocations: A Report Of Two Cases, Özcan Pehli̇van, Can Solakoğlu, İbrahi̇m Akmaz Jan 2003

Subtalar Dislocations: A Report Of Two Cases, Özcan Pehli̇van, Can Solakoğlu, İbrahi̇m Akmaz

Turkish Journal of Medical Sciences

HLİVAN Can SOLAKOĞLU İbrahim AKMAZ Department of Orthopedics and Traumatology, Gülhane Military Medical Academy, Haydarpaşa Training Hospital, İstanbul - Turkey

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Bilateral Intratesticular Varicocele In A Patient With A History Of Bilateral Cryptorchidism, Nuri̇ Erdoğan, Oğuz Ekmekçi̇oğlu, Murat Baykara Jan 2003

Bilateral Intratesticular Varicocele In A Patient With A History Of Bilateral Cryptorchidism, Nuri̇ Erdoğan, Oğuz Ekmekçi̇oğlu, Murat Baykara

Turkish Journal of Medical Sciences

OĞAN^1 Oğuz EKMEKCİOĞLU^2 Murat BAYKARA^1 Departments of ^1Radiology, ^2Urology, Faculty of Medicine, Erciyes University, Kayseri, Turkey

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Echinococcus Infestation Of Quadriceps Femoris Muscle Misdiagnosed As A Soft Tissue Tumor (A Case Report), Kaan Erler, Mahmut Kömürcü, M.Taner Özdemi̇r, Uğur Bariş Özkal, Mustafa Başbozkurt, Ömer Günhan Jan 2003

Echinococcus Infestation Of Quadriceps Femoris Muscle Misdiagnosed As A Soft Tissue Tumor (A Case Report), Kaan Erler, Mahmut Kömürcü, M.Taner Özdemi̇r, Uğur Bariş Özkal, Mustafa Başbozkurt, Ömer Günhan

Turkish Journal of Medical Sciences

ER^1 Mahmut KÖMÜRCÜ^1 M.Taner ÖZDEMİR^1 U. Barış ÖZKAL^1 Mustafa BAŞBOZKURT^1 Ömer GÜNHAN^2 Departments of ^1Orthopedics and Traumatology, ^2Pathology Gülhane Military Medical Academy, Etlik, Ankara - TURKEY

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Peritoneal Defense Mechanisms, Toni̇ Hau Jan 2003

Peritoneal Defense Mechanisms, Toni̇ Hau

Turkish Journal of Medical Sciences

No abstract provided.

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Histological Changes In The Rat Thoracic Aorta After Chronic Nitric Oxide Synthase Inhibition, Ni̇gar Vardi, Feral Öztürk, Ersi̇n Fadillioğlu, Ali̇ Otlu, Murat Yağmurca Jan 2003

Histological Changes In The Rat Thoracic Aorta After Chronic Nitric Oxide Synthase Inhibition, Ni̇gar Vardi, Feral Öztürk, Ersi̇n Fadillioğlu, Ali̇ Otlu, Murat Yağmurca

Turkish Journal of Medical Sciences

The objective of this study was to determine the morphological effects of chronic nitric oxide (NO) inhibition on the thoracic aorta of Wistar rats. Fifteen male Wistar Albino rats were divided into three groups. Group I rats (control group, n = 5) received tap water, group II rats (n = 5) recieved 100 mg/kg L-NAME (moderate NO inhibiton) and group III rats (n = 5) received 500 mg/kg L-NAME, in drinking water (severe NO inhibition) for 15 days. At the end of 15 days, the carotid arteries of the rats were cannulated and their blood pressure was measured. The rats …

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A Preliminary Study Of Dna Damage In Peripheral Lymphocytes From Lung Cancer Patients And Healthy Subjects, Arthur See King Sham, Yim Tong Szeto, Iris Frances Foster Benzie, Kian Cheng Tan-Un Jan 2003

A Preliminary Study Of Dna Damage In Peripheral Lymphocytes From Lung Cancer Patients And Healthy Subjects, Arthur See King Sham, Yim Tong Szeto, Iris Frances Foster Benzie, Kian Cheng Tan-Un

Turkish Journal of Medical Sciences

A pilot study was undertaken to investigate the differences in oxidative DNA damage and 2-h DNA repair in peripheral lymphocytes between lung cancer patients and healthy subjects. Twenty-four lung cancer patients and 23 normal controls were recruited from the Queen Mary Hospital, Hong Kong SAR, China. Single cell gel electrophoresis (comet assay) was performed to measure the oxidative damage, repair and baseline of peripheral lymphocytes in the subjects. There were no significant differences in baseline DNA damage and oxidative stress damage and DNA repair at 2 h among the two groups of lung cancer patients who had blood taken before …

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Tissue Plasminogen Activator Mass Concentration In Ischemic Acute Stroke Patients, Cavi̇t Boz, Abdurrahman Akbaş, Zekeri̇ya Ali̇oğlu, Mehmet Özmenoğlu Jan 2003

Tissue Plasminogen Activator Mass Concentration In Ischemic Acute Stroke Patients, Cavi̇t Boz, Abdurrahman Akbaş, Zekeri̇ya Ali̇oğlu, Mehmet Özmenoğlu

Turkish Journal of Medical Sciences

The role of endogenous fibrinolysis in cerebral infarction has been investigated, but with conflicting results. In this study, variations of tissue-type plasminogen activator (t-PA) antigen concentrations over time after stroke were examined at the acute and subacute phases of ischemic stroke in a group of patients and in a control group. The relationships between t-PA levels and stroke severity, lesion volume and clinical status were also investigated. This study was carried out in 45 patients with acute ischemic stroke and 21 control subjects who had similar characteristics. Levels of t-PA mass concentration were measured via the ELISA, while Student's t, …

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Fasting And Post-Methionine Load Plasma Homocysteine Levels In Patients With Angiographically Defined Coronary Artery Disease, Mustafa Özkan, M. Kemal Erbi̇l, Münzer Al Rashed, Emi̇n Özgür Akgül, Tuncer Çayci, Cumhur Bi̇lgi̇, Gürkan Meti̇nyurt, Şeri̇f Akman, Türker Kutluay Jan 2003

Fasting And Post-Methionine Load Plasma Homocysteine Levels In Patients With Angiographically Defined Coronary Artery Disease, Mustafa Özkan, M. Kemal Erbi̇l, Münzer Al Rashed, Emi̇n Özgür Akgül, Tuncer Çayci, Cumhur Bi̇lgi̇, Gürkan Meti̇nyurt, Şeri̇f Akman, Türker Kutluay

Turkish Journal of Medical Sciences

Elevated plasma homocysteine concentration either in fasting state or after methionine loading is an independent risk factor for vascular disease. The aim of this study was to evaluate the relationship between fasting total homocysteine (tHcy) and post-methionine load tHcy in healthy control subjects and in patients with angiographically defined coronary artery disease (CAD). Methionine loading has been used to investigate impaired methionine metabolism, especially of the trans-sulphuration pathway. We investigated the effect of methionine excess on total plasma homocysteine in 65 control subjects (44 men and 21 women) who attended a polyclinic of Gülhane Military Medical Academy (GMMA) in Ankara. …

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Hemodynamic Changes After Aortopulmonary Separation, Ersi̇n Fadillioğlu, M. Kemal Irmak, Murat Yağmurca, Hasan Erdoğan Jan 2003

Hemodynamic Changes After Aortopulmonary Separation, Ersi̇n Fadillioğlu, M. Kemal Irmak, Murat Yağmurca, Hasan Erdoğan

Turkish Journal of Medical Sciences

The neural crest origin of the aortopulmonary septum has led us to investigate the septum. We designed the present study to assess the hemodynamic changes following aortopulmonary separation in the rat. We freed the ascending aorta from the pulmonary artery by blunt dissection and placed aluminium foil between them in anesthetized, ventilated, open-chest animals and found that the procedure resulted in a slight but significant increase in systolic and diastolic blood pressure and in an insignificant elevation of the heart rate. The hemodynamic deterioration observed after the separation process might be a result of a possible function of the aortopulmonary …

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Chemokine Receptor Cxcr4 Expression In The Major Salivary Gland, Çağri Deli̇lbaşi Jan 2003

Chemokine Receptor Cxcr4 Expression In The Major Salivary Gland, Çağri Deli̇lbaşi

Turkish Journal of Medical Sciences

LİLBAŞI Osaka University, Graduate School of Dentistry, First Department of Oral and Maxillofacial Surgery

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The Effects Of Parenting Modes Of Our Middle Class On The Future Behavior Of Early Adolescents: A Behavioral Analytical Point Of View, Sabi̇ha Keski̇n Jan 2003

The Effects Of Parenting Modes Of Our Middle Class On The Future Behavior Of Early Adolescents: A Behavioral Analytical Point Of View, Sabi̇ha Keski̇n

Turkish Journal of Medical Sciences

Using the statements of 352 14-year-old early adolescents, 183 boys and 154 girls, with no history of conduct disorder, we surveyed the implications of how the behavior modification modes of our middle class will affect the future behavior of the subjects. Severe reprimand (53%), privilege removal (31%) and intense painful stimuli (12%) were the behavior managing modes used by the mother (53%), father (25%) or tutor (12%). The punishing effect (a decrease in the future frequency of the target behavior) of the above worsening conditions was only 8%, whereas the reinforcing effect (an increase in the future frequency of the …

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Carcinoma Of The Cecum: An Unusual Cause Of Fournier's Gangrene, Safvet Örs, Oğuz Ekmekci̇oğlu, Ati̇la Çoruh, Gali̇p K. Günay Jan 2003

Carcinoma Of The Cecum: An Unusual Cause Of Fournier's Gangrene, Safvet Örs, Oğuz Ekmekci̇oğlu, Ati̇la Çoruh, Gali̇p K. Günay

Turkish Journal of Medical Sciences

RS^1 Oğuz EKMEKCİOĞLU^2 Atila ÇORUH^1 Galip K. GÜNAY^1 Departments of ^1Plastic Surgery and ^2Urology, Faculty of Medicine, Erciyes University Kayseri - TURKEY

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Repair Of Myeloschisis Defect With Tutoplast, Mehmet Dumlu Aydin Jan 2003

Repair Of Myeloschisis Defect With Tutoplast, Mehmet Dumlu Aydin

Turkish Journal of Medical Sciences

umlu AYDIN Department of Neurosurgery, Faculty of Medicine, Atatürk University, Erzurum - Turkey

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Treatment Of Clot Retention With Intravesical Streptokinase Instillation, Sema Uğuralp, Necla Gürbüz, Tamer Baysal Jan 2003

Treatment Of Clot Retention With Intravesical Streptokinase Instillation, Sema Uğuralp, Necla Gürbüz, Tamer Baysal

Turkish Journal of Medical Sciences

RALP^1 Necla GÜRBÜZ^1 Tamer BAYSAL^2 Departments of ^1Pediatric Surgery, and ^2Radiology, Faculty of Medicine, Turgut Özal Medical Center, İnönü University, Malatya, Turkey

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Curbing State Discrimination Against Disabled Drivers: Why The Disabled Need Not Pay The States To Participate In Disabled Parking Programs, Joseph Groshong Jan 2003

Curbing State Discrimination Against Disabled Drivers: Why The Disabled Need Not Pay The States To Participate In Disabled Parking Programs, Joseph Groshong

Seton Hall Law Review

No abstract provided.

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The Gatekeeping Role In Civil Litigation And The Abdication Of Legal Values In Favor Of Scientific Values, Neil B. Cohen Jan 2003

The Gatekeeping Role In Civil Litigation And The Abdication Of Legal Values In Favor Of Scientific Values, Neil B. Cohen

Seton Hall Law Review

No abstract provided.

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Liberating Legal Education From The Judicial Model, Muriel Morisey Jan 2003

Liberating Legal Education From The Judicial Model, Muriel Morisey

Seton Hall Journal of Legislation and Public Policy

No abstract provided.

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Telemedicine: The Practice Of Medicine At A Distance, Philip A. Reed Jan 2003

Telemedicine: The Practice Of Medicine At A Distance, Philip A. Reed

STEMPS Faculty Publications

Discusses the increase in the effectiveness and uses of telemedicine due to developments and advances in computing, imaging and telecommunications. History of telemedicine; Information on various areas of telemedicine; Reasons for disappearance of physicians' handwriting problems.

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The Health Act - A Bad Prescription For Consumers, John Conyers Jr. Jan 2003

The Health Act - A Bad Prescription For Consumers, John Conyers Jr.

Seton Hall Journal of Legislation and Public Policy

No abstract provided.

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A Novel Method Of Reporting C-Erbb-2 Overexpression; Correlation With Grade But Not With Other Prognostic Parameters In Breast Cancer, Mustafa Samur, Şeyda Karaveli̇, Hakan Bozcuk, Eli̇f Pestereli̇, Mustafa Özdoğan, Mustafa Yildiz, Mehmet Artaç, Burhan Savaş Jan 2003

A Novel Method Of Reporting C-Erbb-2 Overexpression; Correlation With Grade But Not With Other Prognostic Parameters In Breast Cancer, Mustafa Samur, Şeyda Karaveli̇, Hakan Bozcuk, Eli̇f Pestereli̇, Mustafa Özdoğan, Mustafa Yildiz, Mehmet Artaç, Burhan Savaş

Turkish Journal of Medical Sciences

Overexpression of erbB-2 protein is a marker of clinically aggressive behavior in breast cancer patients. In general erbB-2 status is reported on a scale from negative to 3+, depending on staining intensity, if more than 10% of the tumor cells are stained. However, the original definition does not take into account the percentage of stained cells in detail, since all samples score in the same way if they are above the cut-off, established at 10%. In this study, we evaluated the erB-B2 overexpression by immunohistochemistry in 169 patients and evaluated any correlation with the other well known prognostic parameters. We …

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The Serum Levels Of Il-1\Beta, Il-6, Il-8 And Tnf-\Alpha In Nonalcoholic Fatty Liver, İlyas Tuncer, Hanefi̇ Özbek, Cevat Topal, İsmai̇l Uygan Jan 2003

The Serum Levels Of Il-1\Beta, Il-6, Il-8 And Tnf-\Alpha In Nonalcoholic Fatty Liver, İlyas Tuncer, Hanefi̇ Özbek, Cevat Topal, İsmai̇l Uygan

Turkish Journal of Medical Sciences

Nonalcoholic fatty liver (NAFL) has an extensive clinical spectrum ranging from simple fatty liver to steatohepatitis and cirrhosis. Its pathogenesis is multifactorial. The aim of our study was to measure the serum levels of some cytokines (IL-1\beta, IL-6, IL-8 and TNF-\alpha), which are thought to play a role in the pathogenesis of NAFL. Thirty subjects (18 males, 12 females) with clinical and laboratory features of hepatosteatosis were enrolled in the study as the patient group (group 1) and 30 healthy subjects (21 males, 9 females) served as controls (group 2). The levels of hepatic transaminases, gamma-glutamyltransferase, alkaline phosphatase, total cholesterol, …

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Benign Localized Fibrous Tumor Of The Pleura: Report Of Three Cases And A Review Of The Literature, Ni̇hal Kilinç, Ali̇ Kemal Uzunlar Jan 2003

Benign Localized Fibrous Tumor Of The Pleura: Report Of Three Cases And A Review Of The Literature, Ni̇hal Kilinç, Ali̇ Kemal Uzunlar

Turkish Journal of Medical Sciences

LINÇ, Ali Kemal UZUNLAR Department of Pathology, Faculty of Medicine, Dicle University, Diyarbakır - Turkey

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Determination Of Alkaline Phosphatase Activity In Patients With Different Zinc Metabolic Disorders, Zine Kechrid, Rabah Kenouz Jan 2003

Determination Of Alkaline Phosphatase Activity In Patients With Different Zinc Metabolic Disorders, Zine Kechrid, Rabah Kenouz

Turkish Journal of Medical Sciences

Our purpose was to investigate the effect of different zinc metabolic disorders on alkaline phosphatase activity. Serum zinc, glucose and alkaline phosphatase activity were studied in 32 patients with liver cirrhosis, 30 with chronic renal failure and 42 with insulin-dependent diabetes mellitus (IDDM) compared to 42 healthy volunteers. Serum glucose concentration was significantly higher (P < 0.001) in IDDM and liver cirrhosis patients (P < 0.05) compared to the controls. Serum zinc concentrations tended to be lower in all different diseases but did not reach statistical significance. Alkaline phosphatase activity was higher in IDDM (P < 0.05) and liver cirrhosis patients (P < 0.01) compared with the controls. No positive correlation between serum zinc and alkaline phosphatase activity was recorded in any disease. In conclusion, the investigated diseases did not affect the level of serum zinc; however, there was an alteration in alkaline phosphatase activity in patients suffering from diabetes and liver cirrhosis. Consequently, this may be attributed to the functional disturbance that occurred in these patients. Finally, zinc concentration did not follow alkaline phosphatase activity as indicated by the weak correlation obtained.

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The Nobel Prize In Medicine For 2003 Goes To Magnetic Resonance Imaging, Üstün Aydingöz Jan 2003

The Nobel Prize In Medicine For 2003 Goes To Magnetic Resonance Imaging, Üstün Aydingöz

Turkish Journal of Medical Sciences

No abstract provided.

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Pathophysiological Significance Of Blood Rheology, Oğuz Keri̇m Başkurt Jan 2003

Pathophysiological Significance Of Blood Rheology, Oğuz Keri̇m Başkurt

Turkish Journal of Medical Sciences

Tissue perfusion is determined by both blood vessel geometry and the rheological properties of blood. Blood is a non-Newtonian fluid, its viscosity being dependent on flow conditions. Blood and plasma viscosities, as well as the rheological properties of blood cells (e.g., deformability and aggregation of red blood cells), are influenced by disease processes and extreme physiological conditions. These rheological parameters may in turn affect the blood flow in vessels, and hence tissue perfusion. Unfortunately it is not always possible to determine if a change in rheological parameters is the cause or the result of a disease process. The hemorheology-tissue perfusion …

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Ventilator Associated Pneumonia In Critically Ill Patients: Prevention And Treatment, Argyris Michalopoulos, Stefanos Geroulanos Jan 2003

Ventilator Associated Pneumonia In Critically Ill Patients: Prevention And Treatment, Argyris Michalopoulos, Stefanos Geroulanos

Turkish Journal of Medical Sciences

No abstract provided.

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