Digital Commons Network^™

Sami Matters (Winter 2002), Center For Evidence Based Practices

SAMI Matters

A newsletter of the Ohio Substance Abuse and Mental Illness Coordinating Center of Excellence (SAMI CCOE). The SAMI CCOE is a partnership between the Cuyahoga County Community Mental Health Research Institute at the Mandel School of Applied Social Sciences, Case Western Reserve University (CWRU) and the Department of Psychiatry at the School of Medicine, CWRU. The partnership is in collaboration with the Ohio Department of Mental Health.

The Tiger Orientation Issue Summer 2002, Clemson University

Tiger Newspapers

No abstract provided.

Adobe Medicus 2002 1 January-February, Health Sciences Library And Informatics Center

adobe medicus

No abstract provided.

Adobe Medicus 2002 2 January-March, Health Sciences Library And Informatics Center

adobe medicus

No abstract provided.

Clemson Graduate School Catalog, 2002-2003, Clemson University

Clemson Graduate Announcements

No abstract provided.

New Mph Students Orientation & Training, Jonathan Eldredge

Theory and Practice Seminars 2001-2009

No abstract provided.

Pathways Third Grade Curriculum Manual, Prevention Research Center, Albuquerque, New Mexico

Third Grade Curriculum

No abstract provided.

Pathways Third Grade Curriculum - Week Seven, Prevention Research Center, Albuquerque, New Mexico

Third Grade Curriculum

No abstract provided.

Pathways Third Grade Curriculum - Week Six, Prevention Research Center, Albuquerque, New Mexico

Third Grade Curriculum

No abstract provided.

Pathways Third Grade Curriculum - Week Five, Prevention Research Center, Albuquerque, New Mexico

Third Grade Curriculum

No abstract provided.

Pathways Third Grade Curriculum - Week Four, Prevention Research Center, Albuquerque, New Mexico

Third Grade Curriculum

No abstract provided.

Pathways Third Grade Curriculum - Week Three, Prevention Research Center, Albuquerque, New Mexico

Third Grade Curriculum

No abstract provided.

Pathways Fifth Grade Kitchen Contact Form, Prevention Research Center, Albuquerque, New Mexico

Food Services

No abstract provided.

Pathways Physical Activity Questionnaire, Prevention Research Center, Albuquerque, New Mexico

Other Important Forms

No abstract provided.

Pathways Fifth Grade Family Fun Night Roster, Prevention Research Center, Albuquerque, New Mexico

Family Fun Nights

No abstract provided.

Brown Treesnake Control: Ecomony Of Scales, Daniel S. Vice, Mikel E. Pitzler

Human Conflicts with Wildlife: 2002 Symposium

The accidental introduction of the brown treesnake (Boiga irregularis) to Guam led to the demise of most of the island’s native avifauna and herpetofauna. The snake is also responsible for significant economic losses through frequent power outages and consumption of poultry. Control of the snake, aimed at preventing its inadvertent dispersal from the island and protecting native wildlife and economic resources, is accomplished using specially designed snake traps, hand capture, snake detector dogs, and snake barriers. Although control tools capture large numbers of snakes, control efforts are labor intensive, costly, and ineffective in reducing snake populations across the …

Active Surveillance For Scrapie By Third Eyelid Biopsy And Genetic Susceptibility Testing Of Flocks Of Sheep In Wyoming, Katherine I. O'Rourke, John V. Duncan, James R. Logan, Anne K. Anderson, Dianne K. Norden, Elizabeth S. Williams, Bret A. Combs, Robert H. Stobart, Gary E. Moss, Diane L. Sutton

Zoonotics and Wildlife Disease: Publications

Control of scrapie, an ovine transmissible spongiform encephalopathy or prion disorder, has been hampered by the lack of conventional antemortem diagnostic tests. Currently, scrapie is diagnosed by postmortem examination of the brain and lymphoid tissues for PrP^Sc, the protein marker for this group of disorders. For live, asymptomatic sheep, diagnosis using tonsil or third-eyelid lymphoid tissue biopsy and PrP^Sc assay has been described. To evaluate the feasibility and efficacy of third-eyelid testing for identification of infected flocks and individual infected sheep, 690 sheep from 22 flocks were sampled by third-eyelid lymphoid tissue biopsy and immunohistochemistry. Sheep were …

Comparison Of Histological Lesions And Immunohistochemical Staining Of Proteinase-Resistant Prion Protein In A Naturally Occurring Spongiform Encephalopathy Of Free-Ranging Mule Deer (Odocoileus Hemionus) With Those Of Chronic Wasting Disease Of Captive Mule Deer, T. R. Spraker, R. R. Zink, B. A. Cummings, M. A. Wild, M. W. Miller, Katherine I. O'Rourke

Zoonotics and Wildlife Disease: Publications

In this investigation, the nature and distribution of histologic lesions and immunohistochemical staining (IHC) of a proteinase-resistant prion protein were compared in free-ranging mule deer (Odocoileus hemionus) dying of a naturally occurring spongiform encephalopathy (SE) and captive mule deer dying of chronic wasting disease (CWD). Sixteen free-ranging deer with SE, 12 free-ranging deer without SE, and 10 captive deer with CWD were examined at necropsy. Tissue sections were stained with hematoxylin and eosin, and duplicate sections were stained with a monoclonal antibody (F89/160.1.5). Histological lesions in the freeranging deer with SE and captive deer with CWD were found …

Montana Wolf Conservation And Management Planning Document

Rocky Mountain Wolf Recovery: Annual Reports

Executive Summary

The State of Montana recognizes the gray wolf as a native species and will integrate wolves as a valuable part of our wildlife heritage. Since 1973, the U.S. Fish and Wildlife Service (USFWS) has managed wolves as an endangered species in Montana, under the authority of the Endangered Species Act (ESA). Wolves are likely to be removed from the endangered species list within 3-5 years. Upon delisting, management authority for wolves will return to Montana Fish, Wildlife & Parks (MFWP). MFWP recognizes and accepts the challenges, responsibilities, and benefits of a restored wolf population. Managing gray wolves will …

A Case History Of Wolf-Human Encounters In Alaska And Canada, Mark E. Mcnay, Mary V. Hicks

Rocky Mountain Wolf Recovery: Annual Reports

Executive Summary

Currently there are an estimated 59,000-70,000 wolves (Canis lupus) in Alaska and Canada. Past reviews of wolf-human interactions concluded that wild, healthy wolves in North America present little threat to human safety. However, since 1970 some cases have appeared in the published literature documenting wold aggression toward people. A wolf attack on a 6-year-old boy near Icy Bay, Alaska in April 2000 generated debate in Alaska that challenged previous assumptions regarding the potential danger of wolves to people. At that time there was no recently compiled record of wolf-human encounters for either Alaska or Canada.

To provide a …

Children's Mercy Annual Report 2001, Children's Mercy Hospital

Children's Mercy Annual Reports

Annual report for The Children's Mercy Hospital in Kansas City MO, a pediatric medical center.

Sorption Of Cs+ To Micaceous Subsurface Sediments From The Hanford Site, Usa, John M. Zachara, Steven Smith, Chongxuan Liu, James Mckinley, R. Jeffrey Serne, Paul Gassman

United States Department of Energy: Publications

The sorption of Cs⁺ was investigated over a large concentration range (10^-9–10^-2 mol/L) on subsurface sediments from a United States nuclear materials site (Hanford) where high-level nuclear wastes (HLW) have been accidentally released to the vadose zone. The sediment sorbs large amounts of radiocesium, but expedited migration has been observed when HLW (a NaNO₃ brine) is the carrier. Cs⁺ sorption was measured on homoionic sediments (Na⁺, K⁺, Ca²⁺) with electrolyte concentrations ranging from 0.01 to 1.0 mol/L. In Na⁺ electrolyte, concentrations were extended to near saturation with …

A Pharmacokinetic Model For Estimating Exposure Of Americans To Dioxin-Like Compounds In The Past, Present, And Future, Matthew Lorber

United States Environmental Protection Agency: Publications

Empirical evidence suggests that exposure of Americans to dioxin-like compounds was low during the early decades of the 20th century, then increased during the 1940s and 1950s, reaching a peak in the 1960s and 1970s, and progressively decreased to lower levels in the 1980s and 1990s.Such evidence includes dioxin analysis of carbon-dated sediment cores of lakes and rivers, preserved meat samples from different decades of the 20th century, and limited body burden measurements of dioxin-like compounds. Pinsky and Lorber (1998) summarized studies measuring 2,3,7,8-TCDD in blood and adipose tissue, and found a range of 10–20 pg/g (ppt) lipid during the …

Overview Of The Use Of The The U.S. Epa Exposure Factors Handbook, Jacqueline Moya, Linda Phillips

United States Environmental Protection Agency: Publications

Risk assessments are important components of the decision making process. At hazardous waste sites, they are used as tools to determine appropriate cleanup levels. Therefore, it is critical that the best up-to-date methods, models, and exposure data are available to the exposure and risk assessor to realistically estimate the potential for human and ecological exposures to environmental contaminants. The EPA Exposure Factors Handbook published in 1997 is a tool available to exposure assessors which summarizes statistical data on exposure factors necessary to conduct human health exposure assessments. Since it was first published by EPA in 1989, the handbook has been …

Chemical Contaminants In Juvenile Gray Whales (Eschrichtius Robustus) From A Subsistence Harvest In Arctic Feeding Grounds, Karen L. Tilbury, John E. Stein, Cheryl A. Krone, Robert L. Brownell Jr., S.A. Blokhin, Jennie L. Bolton, Don W. Ernest

United States Department of Commerce: Staff Publications

Gray whales are coastal migratory baleen whales that are benthic feeders. Most of their feeding takes place in the northern Pacific Ocean with opportunistic feeding taking place during their migrations and residence on the breeding grounds. The concentrations of organochlorines and trace elements were determined in tissues and stomach contents of juvenile gray whales that were taken on their Arctic feeding grounds in the western Bering Sea during a Russian subsistence harvest. These concentrations were compared to previously published data for contaminants in gray whales that stranded along the west coast of the US during their northbound migration. Feeding in …

A New Class Of Lipid Desaturase Central To Sphingolipid Biosynthesis And Signalling, Johnathan A. Napier, Louise V. Michaelson, Teresa M. Dunn

Uniformed Services University of the Health Sciences

Sphingolipids and their phosphorylated metabolites play crucial roles in intracellular signaling in animals, and evidence is emerging for analogous situations in fungi and plants. Central to this signaling pathway is the phosphorylation of the sphingoid long chain base, sphingosine, which yields sphingosine-1-phosphate. Until recently, the enzyme responsible for the biosynthesis of sphingosine was unknown, but the Δ4-long chain base desaturase that carries out this reaction has now been identified. Orthologues are present in animals, plants and fungi, raising the possibility of using reverse genetics to determine the contribution of sphingosine-1-phosphate to signaling networks.

A Saccharomyces Cerevisiae Gene Required For Heterologous Fatty Acid Elongase Activity Encodes A Microsomal Β-Keto-Reductase, Frédéric Beaudoin, Ken Gable, Olga Sayanova, Teresa Dunn, Johnathan A. Napier

Uniformed Services University of the Health Sciences

A number of Saccharomyces cerevisiae membranebound oxidoreductases were examined for potential roles in microsomal fatty acid elongation, by assaying heterologous elongating activities in individual deletion mutants. One yeast gene, YBR159w, was identified as being required for activity of both the Caenorhabditis elegans elongase PEA₁ (F₅₆H_11.4) and the Arabidopsis thaliana elongase FAE₁. Ybr159p shows some limited homology to human steroid dehydrogenases and is a member of the short-chain alcohol dehydrogenase superfamily. Disruption of YBR159w is not lethal, in contrast to previous reports, although the mutants are slow growing and display high temperature sensitivity. Both …

The Saccharomyces Cerevisiae Ybr159w Gene Encodes The 3-Ketoreductase Of The Microsomal Fatty Acid Elongase, Gongshe Han, Ken Gable, Sepp D. Kohlwein, Frédéric Beaudoin, Johnathan A. Napier, Teresa M. Dunn

Uniformed Services University of the Health Sciences

The YBR159w gene encodes the major 3-ketoreductase activity of the elongase system of enzymes required for very long-chain fatty acid (VLCFA) synthesis. Mutants lacking the YBR159w gene display many of the phenotypes that have previously been described for mutants with defects in fatty acid elongation. These phenotypes include reduced VLCFA synthesis, accumulation of high levels of dihydrosphingosine and phytosphingosine, and accumulation of medium-chain ceramides. In vitro elongation assays confirm that the ybr159Δ mutant is deficient in the reduction of the 3-ketoacyl intermediates of fatty acid elongation. The ybr159Δ mutant also displays reduced dehydration of the 3-OH acyl intermediates of fatty …

Cell Surface-Localized Nucleolin Is A Eukaryotic Receptor For The Adhesin Intimin-Γ Of Enterohemorrhagic Escherichia Coli O157:H7, James F. Sinclair, Alison D. O'Brien

Uniformed Services University of the Health Sciences

Intimin-γ is an outer membrane protein of enterohemorrhagic Escherichia coli (EHEC) O157:H7 that is required for the organism to adhere tightly to HEp-2 cells and to colonize experimental animals. Another EHEC O157:H7 protein, the Transferred intimin receptor (Tir), is considered the primary receptor for intimin-γ. Nevertheless, Tir-independent binding of intimin-γ to HEp-2 cells has been reported. This observation suggests the existence of a eukaryotic receptor(s) for intimin-γ. In this study, we sought to identify that receptor(s). First, we determined by equilibrium binding titration that the association of purified intimin-γ with HEp-2 cells was specific and consistent …

Unopa Notes 2002

UNOPA: Newsletters

No abstract provided.