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2001

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Plant-Based Multicomponent Vaccines Against Enteric Diseases, Jie Yu Mar 2001

Plant-Based Multicomponent Vaccines Against Enteric Diseases, Jie Yu

Loma Linda University Electronic Theses, Dissertations & Projects

To generate a plant-based multicomponent oral vaccine against cholera, rotavirus and enterotoxigenic E.coli (ETEC), we have constructed transgenic potato plants that synthesize the cholera toxin B and A2 subunits, the rotavirus enterotoxin NSP4 22 amino acid epitope and the ETEC fimbrial antigen CFA/L To use cholera toxin as a carrier molecule for delivery of multiple antigens to the gut-associated lymphoid tissues, the rotavirus NSP4 epitope was linked to the cholera toxin B subunit (CTB) and the ETEC fimbrial antigen CFA/I was linked to the cholera toxin A2 subunit. Cholera toxin-antigen fusion proteins were detected in transformed tuber tissues by immunoblot …

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A Mechanistic Model For Internal Bone Remodeling Exhibits Different Dynamic Responses In Disuse And Overload, Scott J. Hazelwood, R. Bruce Martin, Mark M. Rashid, Juan J. Rodrigo Mar 2001

A Mechanistic Model For Internal Bone Remodeling Exhibits Different Dynamic Responses In Disuse And Overload, Scott J. Hazelwood, R. Bruce Martin, Mark M. Rashid, Juan J. Rodrigo

Biomedical Engineering

Bone is a dynamic tissue which, through the process of bone remodeling in the mature skeleton, renews itself during normal function and adapts to mechanical loads. It is, therefore, important to understand the effect of remodeling on the mechanical function of bone, as well as the effect of the inherent time lag in the remodeling process. In this study, we develop a constitutive model for bone remodeling which includes a number of relevant mechanical and biological processes and use this model to address differences in the remodeling behavior as a volume element of bone is placed in disuse or overload. …

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Intelligent Design: The Bridge Between Science And Theology (Book Review), James Mahaffy Mar 2001

Intelligent Design: The Bridge Between Science And Theology (Book Review), James Mahaffy

Pro Rege

Reviewed Title: Intelligent Design: The Bridge Between Science and Theology, by William A. Dembski (Downers Grove, IL: InterVarsity Press, 1999). 312 pages. ISBN 0-830-815813.

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Academic Fads And Fashions (With Special Reference To Law), Cass R. Sunstein Mar 2001

Academic Fads And Fashions (With Special Reference To Law), Cass R. Sunstein

Coase-Sandor Institute for Law & Economics Research Paper Series

Like everyone else, academics are susceptible to informational and reputational signals. Sometimes academics lack confidence in their methods and beliefs, and they pay a great deal of attention to the methods and beliefs of others. The academic study of law is particularly subject to cascade effects, as people follow signals that they participate in amplifying. Some of these effects run their course quickly, whereas others last a long time. Leaders can play a special role in starting and stopping cascades; external shocks play a special role in the academic study of law; sometimes like-minded people within academia move one another …

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Adobe Medicus 2001 2 March-September, Health Sciences Library And Informatics Center Mar 2001

Adobe Medicus 2001 2 March-September, Health Sciences Library And Informatics Center

adobe medicus

No abstract provided.

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Arsenic Alters The Function Of The Glucocorticoid Receptor As A Transcription Factor, Ronald C. Kaltreider, Alisa M. Davis, Jean P. Lariviere, Joshua W. Hamilton Mar 2001

Arsenic Alters The Function Of The Glucocorticoid Receptor As A Transcription Factor, Ronald C. Kaltreider, Alisa M. Davis, Jean P. Lariviere, Joshua W. Hamilton

Dartmouth Scholarship

Chronic human exposure to nonovertly toxic doses of arsenic is associated with an increased risk of cancer. Although its carcinogenic mechanism is still unknown, arsenic does not directly cause DNA damage or mutations and is therefore thought to act principally as a co-mutagen, co-carcinogen, and/or tumor promoter. Previous studies in our laboratory demonstrated that effects of low-dose arsenic (III) (arsenite) on expression of the hormone-regulated phosphoenolpyruvate carboxykinase (PEPCK) gene were strongly associated with the glucocorticoid receptor (GR)-mediated regulatory pathway. We therefore examined specifically the effects of arsenite on the biochemical function of GR in hormone-responsive H4IIE rat hepatoma cells. Completely …

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University Reporter - Vol. 05, No. 07 - March 2001, University Of Massachusetts Boston Mar 2001

University Reporter - Vol. 05, No. 07 - March 2001, University Of Massachusetts Boston

1996-2009, University Reporter

No abstract provided.

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Gender, Literature, And Film In Contemporary East Central European Culture, Anikó Imre Mar 2001

Gender, Literature, And Film In Contemporary East Central European Culture, Anikó Imre

CLCWeb: Comparative Literature and Culture

In her article, "Gender, Literature, and Film in Contemporary East Central European Culture," Anikó Imre discusses gender, literature, and film in Hungary in the context of East Central European national cultures of the 1980s and 1990s. Anikó Imre analyzes the analogous gender structures that underlie both nation and literature in these transitional cultures. She challenges both social science studies of post-communist transitions and studies of East Central European literatures and cultures for their traditional neglect of gendered desire as a political factor. Thereby, Imre adopts a deconstructionist, feminist, and post-colonial approach to Hungarian "postmodernist" literature and film, which, similar to …

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Bear Behavior In The Vicinity Of Supplemental Feeding Stations In Western Washington, Dale L. Nolte, Timothy J. Veenendaal, George J. Ziegltrum, Philipp Fersterer Mar 2001

Bear Behavior In The Vicinity Of Supplemental Feeding Stations In Western Washington, Dale L. Nolte, Timothy J. Veenendaal, George J. Ziegltrum, Philipp Fersterer

United States Department of Agriculture Wildlife Services: Staff Publications

Black bear can inflict severe negative Impacts on timber stands in the northwestern United States. A supplemental feeding program to provide bears an alternative food source during spring is practiced in the stat e of Washington, and to a lesser extent in other states. We initiated concurrent studies to assess characteristics of bear that forage at feeding stations, the interactions of bears around feeders, and impacts of the program on bear territories. Numerous bears fed at stations, including females with and without cubs, yearlings. and males. Bear feeding bouts at stations were generally short, less than 15 minutes. Bears generally …

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Testimonial Poetry In East European Post-Totalitarian Literature, Albena Lutzkanova-Vassileva Mar 2001

Testimonial Poetry In East European Post-Totalitarian Literature, Albena Lutzkanova-Vassileva

CLCWeb: Comparative Literature and Culture

In her article, "Testimonial Poetry in East European Post-Totalitarian Literature," Albena Lutzkanova-Vassileva reexamines the belief that postmodern literature and deconstructive writing have parted literary and theoretical discourse from reality, thereby obstructing and annihilating our access to history. Lutzkanova-Vassileva exemplifies her prognosis in an inquiry into post-totalitarian and postmodern Bulgarian literature and its texts of poetry. Born in the turmoil of communism's debacle, the analysis is an attempt to illustrate that, contrary to denying reference, postmodernism solely rejects the reduction of reference to a world that is perceptible and cognitively masterable. Rethinking what many have seen as a self-referential literature, with …

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A Dickensian Era Of Religious Rights: An Update On Religious Human Rights In Global Perspective, John Witte Jr. Mar 2001

A Dickensian Era Of Religious Rights: An Update On Religious Human Rights In Global Perspective, John Witte Jr.

William & Mary Law Review

No abstract provided.

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Biophilia, The Endangered Species Act, And A New Endangered Species Paradigm, L. Misha Preheim Mar 2001

Biophilia, The Endangered Species Act, And A New Endangered Species Paradigm, L. Misha Preheim

William & Mary Law Review

No abstract provided.

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The Cowl - V.65 - No. 18 - Mar 1, 2001 Mar 2001

The Cowl - V.65 - No. 18 - Mar 1, 2001

The Cowl

The Cowl - student newspaper of Providence College. The Cowl - Vol 65 - No. 18 - March 1, 2001. 32 pages.

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Illinois State University Report, March 1, 2001, Illinois State University Mar 2001

Illinois State University Report, March 1, 2001, Illinois State University

Illinois State University Report (1966-2012)

Illinois State University bi-weekly employee newsletter.

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Meridians 1:2, Kum-Kum Bhavnani Mar 2001

Meridians 1:2, Kum-Kum Bhavnani

Meridians: Feminism, Race, Transnationalism

The end of the twentieth century marks a time of realignments in the cultural and political economies of gender throughout the world. Protests in many places against the World Trade Organization, the International Monetary Fund, and the World Bank have brought together a range of constituencies which had been fairly remote from each other in the previous decade....

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The Colby Echo (2001-03-01), Colby College Mar 2001

The Colby Echo (2001-03-01), Colby College

The Colby Echo

Published by the students of Colby College since 1877, The Colby Echo is the weekly, editorially independent student-run newspaper of Colby College in Waterville, Maine. Published monthly, 1877-1886; semi-monthly, 1886-1897; and weekly, during the academic year, 1898-present.

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The Army And Homeland Security: A Strategic Perspective, Antulio J. Echevarria Ii Mar 2001

The Army And Homeland Security: A Strategic Perspective, Antulio J. Echevarria Ii

Books, Monographs & Collaborative Studies

The topic of homeland security includes a broad array of missions and mission areas ranging from national missile defense to military assistance to civil authorities. The topic has recently attracted a great deal of attention due to the public's heightened awareness of the variety and nature of emerging threats and of the United States vulnerabilities to them. The Army Staff was assigned to investigate the Army's role in homeland security from a strategic, rather than a legal or procedural perspective. The author achieves this perspective by placing homeland security missions within the larger spectrum of operations. In so doing, he …

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Disrupting Evolutionary Processes: The Effect Of Habitat Fragmentation On Collared Lizards In The Missouri Ozarks, Alan R. Templeton, Robert J. Robertson, Jennifer A. Brisson, Jared Strasburg Mar 2001

Disrupting Evolutionary Processes: The Effect Of Habitat Fragmentation On Collared Lizards In The Missouri Ozarks, Alan R. Templeton, Robert J. Robertson, Jennifer A. Brisson, Jared Strasburg

School of Biological Sciences: Faculty Publications

Humans affect biodiversity at the genetic, species, community, and ecosystem levels. This impact on genetic diversity is critical, because genetic diversity is the raw material of evolutionary change, including adaptation and speciation. Two forces affecting genetic variation are genetic drift (which decreases genetic variation within but increases genetic differentiation among local populations) and gene flow (which increases variation within but decreases differentiation among local populations). Humans activities often augment drift and diminish gene flow for many species, which reduces genetic variation in local populations and prevents the spread of adaptive complexes outside their population of origin, thereby disrupting adaptive processes …

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Genetic And Diurnal Variation In The Juvenile Hormone Titer In A Wing-Polymorphic Cricket: Implications For The Evolution Of Life Histories And Dispersal, Anthony J. Zera, Gretchen Cisper Mar 2001

Genetic And Diurnal Variation In The Juvenile Hormone Titer In A Wing-Polymorphic Cricket: Implications For The Evolution Of Life Histories And Dispersal, Anthony J. Zera, Gretchen Cisper

Anthony Zera Publications

The wing-polymorphic cricket, Gryllus firmus, contains (1) a flight-capable morph (LWf) with long wings and functional flight muscles, (2) a flightless morph with reduced wings and underdeveloped flight muscles (SW), and (3) a flightless morph with histolyzed flight muscles but with fully developed wings (LWh). The LWf morph differed genetically from the SW morph and phenotypically from the LWh morph in the size of flight muscles, ovarian growth during the first week of adulthood, and the hemolymph titer of juvenile hormone (JH). This is the first study to document that phenotypes that differ …

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The Endocrine-Genetic Basis Of Life-History Variation: The Relationship Between The Ecdysteroid Titer And Morph-Specific Reproduction In The Wing-Polymorphic Cricket Gryllus Firmus, Anthony J. Zera, Justin Bottsford Mar 2001

The Endocrine-Genetic Basis Of Life-History Variation: The Relationship Between The Ecdysteroid Titer And Morph-Specific Reproduction In The Wing-Polymorphic Cricket Gryllus Firmus, Anthony J. Zera, Justin Bottsford

Anthony Zera Publications

The hormonal basis of variation in life-history traits is a poorly studied topic in life-history evolution. An important step in identifying the endocrine-genetic causes of life-history variation is documenting statistical and functional associations between hormone titers and genotypes/phenotypes that vary in life-history traits. To this end, we compared the blood ecdysteroid titer and the mass of the ovaries during the first week of adulthood among a flight-capable morph and two fl ightless morphs of the wing-polymorphic cricket Gryllus firmus. Ecdysteroids are a group of structurally related hormones that regulate many important aspects of reproduction in insects. Both the ecdysteroid …

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Effects Of Concentration And Temperature On The Coupled Heat And Mass Transport In Liquid Mixtures, Yaşar Demirel, Stanley I. Sandler Mar 2001

Effects Of Concentration And Temperature On The Coupled Heat And Mass Transport In Liquid Mixtures, Yaşar Demirel, Stanley I. Sandler

Papers in Thermal Mechanics

Using published experimental data on the thermal conductivity, mutual diffusivity, and heats of transport, the degree of coupling between heat and mass flows has been calculated for binary and ternary nonideal liquid mixtures. The binary mixtures consist of two types: the first is six systems of six-to-eight-carbon straight and branched chain alkanes in chloroform and in carbon tetrachloride; and the second is mixtures of carbon tetrachloride with benzene, toluene, 2-propanone, n-hexane, and 11-octane. The ternary mixture considered is toluene-chlorobenzene-bromobenzene. The published data are available at 35°C, 30°C, and 35°C and ambient pressure. Using the linear nonequilibi-ium thermodynainics (LNET) and the …

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Evolution In The Information Age: Rediscovering The Nature Of The Organism, Daniel R. Brooks Mar 2001

Evolution In The Information Age: Rediscovering The Nature Of The Organism, Daniel R. Brooks

Harold W. Manter Laboratory of Parasitology: Faculty Publications

The newest synthesis of evolutionary thought is emerging, and promises to return evolutionary biology to Darwin’s panoramic view of life. The key element is a long-standing dualism in evolutionary theory. This dualism has a long history within evolutionary biology, being manifested under guises such as: (1) the nature of the organism and the nature of the conditions, (2) internal and external, or intrinsic and extrinsic, factors, (3) production and exchanges, (4) boundary and initial conditions, (5) metabolism and replication, (6) energy and information, and (7) costs and benefits, and conflict and resolution. A partially retrospective review suggests that there is …

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Plant-Derived Oils Reduce Pathogens And Gaseous Emissions From Stored Cattle Waste, Vincent H. Varel, Daniel N. Miller Mar 2001

Plant-Derived Oils Reduce Pathogens And Gaseous Emissions From Stored Cattle Waste, Vincent H. Varel, Daniel N. Miller

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Carvacrol and thymol in combination at 6.7 mM each completely inhibited the production of short-chain volatile fatty acids and lactate from cattle waste in anoxic flasks over 23 days. Fecal coliforms were reduced from 4.6 x 106 to 2.0 x 103 cells per ml 2 days after treatment and were nondetectable within 4 days. Total anaerobic bacteria were reduced from 8.4 x 1010 to 1.5 x 107 cells per ml after 2 days and continued to be suppressed to that level after 14 days. If the concentration of carvacrol or thymol were doubled (13.3 mM), either …

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Malicious Hackers: A Framework For Analysis And Case Study, Laura J. Kleen Mar 2001

Malicious Hackers: A Framework For Analysis And Case Study, Laura J. Kleen

Theses and Dissertations

Recent years have seen an increase in the number and severity of Information Operations (IO) attacks upon DoD resources. At a higher level, the US as a whole has come under cyber attack by individuals and groups seeking thrills, monetary gain, publicity for their causes, and myriad other goals. This effort develops a first cut model of individual hacker mentality that can be utilized to improve threat assessment, mitigate Information Assurance (IA) vulnerabilities, and improve risk assessment. Further, it is a first step toward automated characterization of Information Warfare (IW) attacks based upon hacker types. All hackers are not the …

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Solving The Protein Structure Prediction Problem With Fast Messy Genetic Algorithms (Scaling The Fast Messy Genetic Algorithm To Medium-Sized Peptides By Detecting Secondary Structures), Steven R. Michaud Mar 2001

Solving The Protein Structure Prediction Problem With Fast Messy Genetic Algorithms (Scaling The Fast Messy Genetic Algorithm To Medium-Sized Peptides By Detecting Secondary Structures), Steven R. Michaud

Theses and Dissertations

The ability to accurately predict a polypeptide's molecular structure given its amino acid sequence is important to numerous scientific, medical, and engineering applications. Studies have been conducted in the application of Genetic Algorithms (GAs) to this problem with promising initial results. In this thesis report, we use the fast messy Genetic Algorithm (fmGA) to attempt to find the minimization of an empirical CHARMM energy model and generation of the associated conformation. Previous work has shown that the fmGA provided favorable results, at least when applied to the pentapeptide Met-Enkephalin. We extend these results to a larger Polyalinine peptide by utilizing …

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Montana Kaimin, March 1, 2001, Associated Students Of The University Of Montana Mar 2001

Montana Kaimin, March 1, 2001, Associated Students Of The University Of Montana

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

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Quantitative Validation Of A Model Of Chlorinated Ethene Natural Attenuation, Harold C. Young Mar 2001

Quantitative Validation Of A Model Of Chlorinated Ethene Natural Attenuation, Harold C. Young

Theses and Dissertations

Chlorinated ethenes are among the most prevalent groundwater contaminants at hazardous waste sites nationwide. In an attempt to manage the risks posed by these contaminants, while controlling costs, monitored natural attenuation (MNA) is being considered as a remediation strategy at many sites. MNA relies on naturally occurring physical, chemical, and biological processes in the subsurface to reduce the risk posed by the contamination. The implementation of MNA, however, requires a detailed understanding of these processes, and how they impact contamination at a particular site. One way to gain this understanding is through contaminant fate and transport modeling. In this study, …

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Robust Multi-Scenario Optimization Of An Air Expeditionary Force Structure Applying Scatter Search To The Combat Forces Assessment Model, Gokay Bulut Mar 2001

Robust Multi-Scenario Optimization Of An Air Expeditionary Force Structure Applying Scatter Search To The Combat Forces Assessment Model, Gokay Bulut

Theses and Dissertations

Modern Times' bring change in all areas of life. Even the rate of change has changed, and is still changing to increase it's enormous speed even more. Newer and more challenging questions face the military analysts everyday putting a question mark at the end of their last answer. Recently, the question of how to structure a robust air force to meet the requirements of competing, uncertain future scenarios has been keeping them busy. The new world order does not tolerate only being able to respond to a single scenario anymore, which once was considered a hard problem. Who knows what …

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A Radial Basis Function Neural Network Approach To Two-Color Infrared Missile Detection, Kin-Weng Chan Mar 2001

A Radial Basis Function Neural Network Approach To Two-Color Infrared Missile Detection, Kin-Weng Chan

Theses and Dissertations

Multicolor infrared imaging missile-warning systems require real-time detection techniques that can process the wide instantaneous field of regard of focal plane array sensors with a low false alarm rate. Current technology applies classical statistical methods to this problem and ignores neural network techniques. Thus the research reported here is novel in that it investigates the use of radial basis function (RBF) neural networks to detect sub-pixel missile signatures. An RBF neural network is designed and trained to detect targets in two-color infrared imagery using a recently developed regression tree algorithm. Features are calculated for 3 by 3 pixel sub-images in …

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Optimization Of Palladium-Catalyzed In Situ Destruction Of Trichloroethylene-Contaminated Groundwater Using A Genetic Algorithm, Manuel Fernandez Mar 2001

Optimization Of Palladium-Catalyzed In Situ Destruction Of Trichloroethylene-Contaminated Groundwater Using A Genetic Algorithm, Manuel Fernandez

Theses and Dissertations

Conventional technologies for the treatment of groundwater contaminated with chlorinated solvents have limitations that have motivated development of innovative technologies. One such technology currently under development involves using palladium-on-alumina (Pd/Al) as a catalyst to promote dechlorination. Pd/Al catalyst may be used in-well as part of a re-circulating horizontal flow treatment well (HFTW) system. An HFTW system involves two or more dual-screened wells, with in-well reactors, to capture and treat contaminated groundwater without the need to pump the water to the surface. In this study, objective and fitness functions, based on system costs and TCE concentration requirements, were developed to optimize …

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