Digital Commons Network^™

Attention Deficit Hyperactivity Disorder. Epidemiologic, Pathophysiologic, Diagnostic And Treatment Perspectives, Yasser S. Al-Ghamdy, Naseem A. Qureshi

Saudi Medical Journal

Although attention deficit hyperactivity disorder is a common child psychiatric disorder, the epidemiology and pathophysiology of attention deficit hyperactivity disorder is variable in different studies. Attention deficit hyperactivity disorder and comorbid disorders in children aided both by attention deficit hyperactivity disorder diagnostic criteria and assessment scales entails a comprehensive neuropsychiatric interview plus collection of information from different sources. Although psychosocial and behavioral therapies are of great therapeutic values, the psychopharmacological drugs are often used in the treatment of patients with attention deficit hyperactivity disorder. With a combined approach, a substantial proportion of patients with attention deficit hyperactivity disorder (90%) show …

The Louisiana Hydrocarbon Processing Tax, James C. Exnicios

Louisiana Law Review

No abstract provided.

Higher Order Chromatin Degradation Induced By Hydrogen Peroxide In Glial Cells, Raymond Mouzannar

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study addresses the genotoxicity of oxidative stress. We induced oxidative stress in cultured rat oligodendrocytes by exposure to hydrogen peroxide (H2O2). Intact genomic DNA was isolated by agarose embedding and its fragmentation was assessed by field inversion gel electrophoresis (FIGE). To detect single strand fragmentations, the DNA was digested with S1 nuclease before FIGE. We found that the exposure of oligodendrocytes to pathological concentrations of H2O2, induces a rapid digestion of nuclear chromatin in a pattern consistent with higher order chromatin degradation (HOCD). HOCD, the hallmark of programmed cell death (PCD), proceeds through single strand scissions that accumulate at …

A Novel Strategy Utilizing Co-Expression Of Murine Il-12 And Antisense Tgf-Pl Against H238 Tumor Formation, Craig A. Seheult

Loma Linda University Electronic Theses, Dissertations & Projects

Cytokines have a profound effect on immune modulation, thus playing a significant role in cancer gene therapy. A variety of human carcinomas secrete transforming growth factor-beta (TGF-β), a cytokine with potent immunosuppressive properties. Suppressing TGF-β could be a key to successfully combating malignancies, such as gliomas, mammary, and colon cancers, that over-express TGF-β. Conversely, interleukin-12 (IL-12) is a potent immunostimulatory cytokine capable of regulating T and NK cell-mediated cytotoxic responses (Trinchieri, 1994) during an anti-tumor response. Activation of the immune system with such immunostimulatory cytokines renders it inert to the suppressive effects of TGF-β. To better understand these processes our …

Effects Of Liposome-Encapsulated Tnf-Alpha And Radiation Against Colon Cancer, Dong Won Kim

Loma Linda University Electronic Theses, Dissertations & Projects

Previous studies have shown that tumor necrosis factor-α (TNF-α) can augment the antitumor effects of radiation, inhibiting tumor progression to a greater extent than either modality alone. However, nonspecific toxicities associated with TNF-α have limited its use as an adjuvant. This limitation is potentially resolved with the encapsulation of TNF-α in sterically stabilized, PEGylated liposomes (STEALTH®). Thus, the overall hypothesis of the research was that the combination of radiation with STEALTH® liposome encapsulated TNF-α (SL-TNF-α) will have greater efficacy and fewer dose-limiting side effects in the LS174T human colorectal tumor xenograft model compared to the combination of free TNF-α and …

The Impact Of Logging On Aquatic Salamander Communities., Heather Noel Mcdonald

Electronic Theses and Dissertations

For this study, the abundance of the salamander fauna in two streams was compared to determine the impact of logging activities. After five months of study, the area around one stream was logged by the National Forest Service. Following logging, the abundance of salamanders in the stream was greatly reduced, while the population in the undisturbed stream remained relatively unchanged. Six abundant species were used as indicators; two of these species (Desmognathus quadramaculatus and Desmognathus ochrophaeus) were negatively affected by the logging, while four species (Demognathus fuscus, Desmognathus monticola, Eurycea wilderae, and Gyrinophilus porphyriticus …

Remembering The Forgotten Genocide: Armenia In The First World War., Dana Renee Smythe

Electronic Theses and Dissertations

The Ottoman Empire was in serious decline by the late nineteenth century. Years of misrule, war, and oppression of its various nationalities had virtually driven the Turks from Europe, leaving the weakened Empire on the verge of collapse. By the 1870s the Armenians were the most troubling group, having gained international sympathy at the Congress of Berlin. As a result, violence against the Armenians had escalated dramatically by the turn of the century. They felt, however, that their fortune had changed when the liberal Young Turks seized power from the Sultan in 1908. Unfortunately, the Young Turks had a much …

Integrated Modulation Of Sympathetic Tone In The Microcirculation By Oxygen, Adenosine, And Nitric Oxide, Bryan Auston Sauls

Graduate Theses, Dissertations, and Problem Reports (ETD)

Despite a profound reduction in hemodynamic shear stress, a sustained release of endothelium-derived nitric oxide (NO) limits arteriolar constriction during periods of increased sympathetic nerve activity in the rat small intestine. In this project, we sought to test the hypothesis that adenosine, formed in response to a flow-dependent fall in local PO2, serves as the stimulus to preserve endothelial NO release under these conditions. Sympathetic nerve stimulation induced frequency-dependent arteriolar constrictions and a flow-dependent fall in local PO2. The arteriolar responses to nerve stimulation were enhanced after inhibition of NO synthase with NG-monomethyl-L-arginine (L-NMMA). Under a high (20%) O2 superfusate, …

Messianism In The Christian Kabbalah Of Johann Kemper, Elliot Wolfson

Journal of Scriptural Reasoning

No abstract provided.

Carbon Emissions The Problem: Carbon Storage The Solution?, Gary D. Lynne, Colby Kruse

Cornhusker Economics

A recent newspaper story line reads “178 Nations Reach Climate Accord; U.S. Only Looks On” (New York Times Interactive Edition, July 24, 2001). The underlying Press Release from the United Nations Framework Convention on Climate Change (UNFCCC) affirms that indeed many governments have adopted an agreement on Kyoto Protocol rules, including economic powers represented in Japan and the European Union, as well as our neighbors in spirit as well as proximity, Australia and Canada. The UNFCCC is the entity that organizes the meetings of the Conference of the Parties (COP), with 4,500 participants representing 180 nations at the recent July …

The Bg News August 1, 2001, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. August 1, 2001. Volume 87-Issue 7.

Utopia Park, Utopian Church: James K. Humphrey And The Emergence Of The Sabbath-Day Adventists, Romauld C. Jones

Dissertations

James K. Humphrey was a Baptist minister who joined the Seventh-day Adventist Church shortly after migrating to the United States from Jamaica at the turn of the twentieth century. A leader of uncommon skill and charisma, Humphrey ministered in Harlem, New York, during the period the area became the Black capital of the United States, leading his congregation to a position of primacy in the Greater New York Conference of Seventh-day Adventists. Yet Humphrey believed that the African American experience in Adventism was one of disenfranchisement, a problem he attempted to ameliorate with the establishment of the Utopia Park Benevolent …

Numerical Modeling Of Cold Flow And Hot Gas Desulfurization In A Circulating Fluidized Bed, Neeraj N. Pugalia

Graduate Theses, Dissertations, and Problem Reports (ETD)

Section I. This work was carried out to understand the behavior of the solid and gas phases in a CFB riser. Only the riser is modeled as a straight pipe. A model with linear algebraic approximation to solids viscosity of the form, mus = 5.34epsilons, (epsilon s is the solids volume fraction) with an appropriate boundary condition at the wall obtained by approximate momentum balance solution at the wall to account for the solids recirculation is tested against experimental results. The work done was to predict the flow patterns in the CFB risers from available experimental data, including data from …

Seasonal Plasticity Of A15 Dopaminergic Neurons In The Ewe, Van Lee Adams

Graduate Theses, Dissertations, and Problem Reports (ETD)

In the ewe, anestrus is caused by increased sensitivity to E2 negative feedback that is mediated by A15 dopaminergic neurons that are only responsive to E2 in anestrus. Experiment 1, tested the hypothesis that synaptic input on A15 neurons varies with season by examining synapsin-positive close contacts on A15 cells using immunofluorescence and confocal microscopy. The number of contacts on dendrites, but not somata, increased during anestrus. There were also corresponding changes in dendritic morphology including an increase in dendritic length, surface area, and number of bifurcations. Because thyroid hormones are necessary for the transition to anestrus, we next examined …

Transport And Utilization Of Arginine And Arginine-Containing Peptides By Rat Alveolar Macrophages, Xiaodong Yang

Graduate Theses, Dissertations, and Problem Reports (ETD)

Purpose. To demonstrate that alveolar macrophages (AM) from rats exhibit pepT1-like transporter for the uptake of small arginine-containing peptides (ACPs) and utilized these peptides as direct substrates for nitric oxide (NO) production.;Method. A HPLC assay was developed for quantitative measurement of Arg and ACPs in rat plasma and bronchoalveolar lavage (BAL) fluid. The uptake of small peptides by rat AM was evaluated using fluorescein isothiocynate (FITC)-labeled (*) peptides (Arg-Lys*, beta-Ala-Lys*, and Gly-Sar-Lys*), HPLC analysis of potential peptide degradation, and known inhibitors on arginine (Arg) and PepT1 transport. NO production by AM through Arg and ACPs was studied with and without …

Development Of A Micro-Dilution Tunnel System For In-Use, On-Board Heavy-Duty Vehicle Particulate Matter Emissions Measurement, Emily Deanna Cirillo

Graduate Theses, Dissertations, and Problem Reports (ETD)

A novel portable particulate matter measuring system was designed, developed and qualified. The heavy-duty engine Federal Test Procedure (FTP) requires the use of a full-flow tunnel to measure particulate emissions from diesel fueled engines. However, a full-flow tunnel based constant volume sampler (CVS) system is not only expensive to build and maintain, it also requires a large work space. The portable micro-dilution system that could be used for measuring on-board, in-use emissions from heavy-duty vehicles would cost significantly less. The micro-dilution tunnel operates on the same principle as a full-flow dilution tunnel. The added advantage of the proposed design is …

Functional Profiles Of Growth-Related Genes During Embryogenesis And Postnatal Development Of Chicken And Mouse Skeletal Muscle, Hakan Kocamis

Graduate Theses, Dissertations, and Problem Reports (ETD)

Reverse-transcription polymerase chain reaction (RT-PCR) was performed to measure myostatin, follistatin, activin-B gene expressions during chicken embryonic development. Strong myostatin expression was found in the early chicken embryos (E 0, E 1) and the developmental expression pattern of myostatin mRNA coincided with the periods of primary and secondary muscle fiber formation. Follistatin transcripts followed a linear expression pattern from E 0 to E 20, while activin-B had a quadratic pattern. The ontogeny of myostatin gene expression was nearly identical in satellite cells isolated from pectoralis major (PM) and biceps femoris (BF) muscles of chicken. Activin-B mRNA level in PM satellite …

Visual Iconic Object-Oriented Programming To Advance Computer Science Education And Novice Programming, Nancy Silva Martinez

Theses and Dissertations - UTB/UTPA

Learning how to program a computer is difficult for most people. Computer programming is a cognitively challenging, time consuming, labor intensive, and frustrating endeavor. Years of formal study and training are required to learn a programming language's world of algorithms and data structures. Instructions are coded in advance before the computer demonstrates the desired behavior. Seeing all the programming steps and instruction code is complicated. There exists a tremendous gap between the representations the human brain uses when thinking about a problem and the representations used in programming a computer. Often people are much better at dealing with specific, concrete …

Figurative Sculpture In Paper Clay., Valarie G. Lyle

Electronic Theses and Dissertations

The artist discusses her Master of Fine Arts exhibition at East Tennessee State University, Carroll Reece Museum, Johnson City, Tennessee, March 9 - 17, 2001. The exhibition marked her return to organic, gestural work. Works are figurative, ceramic, sculpture, made of paper clay, ranging from 8-inch, wall mounted, bas-relief to life sized, full round figures. Most are slab constructed, unglazed or lightly glazed with soda wash.

Topics discussed: the artist's development, including the influences of Stephen De Staebler, in his treatment of the individual in mass culture, and of Mary Frank, in psychological content and in the use of negative …

Discovery Through Numeric Strata: A Balance Of Form And Aesthetics., Marc Ian Sonenberg

Electronic Theses and Dissertations

This thesis is in support of my Master of Fine Arts exhibition in the Carroll Reece Museum at East Tennessee State University. It describes a body of work that strives for a balance of form and aesthetics. Chapter 1 charts how I refined my personal stylistic qualities. Chapter 2 gives a brief overview of the history of ceramics techique. Chapter 3 discusses the surface treatment and construction of the pieces in the show. Chapter 4 presents each piece in chronological order.

Salmonella Food Poisoning In Najran, Latif A. Khan, Sarosh A. Khan, Venugopal Jayapal, Habeebullah Shah

Saudi Medical Journal

No abstract provided.

Is The Pancreas Responsible For Hyperemens Gravidarum?, Fikra Al-Busaida, A. Krolikowski

Saudi Medical Journal

No abstract provided.

Uses Of Internet Technology In Clinical Practice, Ibrahim Mansoor

Saudi Medical Journal

The practice of medicine has extended itself to vast areas and requires active clinicians to systematize and organize their workload through the use of the most up-to-date digital and computer communication technologies. Computerization and worldwide accessibility of information has especially provided great assistance in this regard. The explosive growth of medical information increases the need for the use of these new methods of organizing and accessing data. This article briefly summarizes a few of the vital tools that internet technology has provided clinical practice, with the aid of basic concepts of internet, database systems, hospital systems and data security and …

Determination Of Diazacon In Quail Feed And Quail Serum By Ion Pair Reversed-Phase Chromatography, John J. Johnston, Margaret J. Goodall, Jerome C. Hurley, Christi A. Yoder, Lowell A. Miller

United States Department of Agriculture Wildlife Services: Staff Publications

Liquid chromatographic (LC) methods were developed for quantitating the potential avian contraceptive DiazaCon in quail feed and serum. DiazaCon was extracted from ground quail feed with basic n-butyl chloride. The n-butyl chloride extract was evaporated to dryness. The DiazaCon residues were dissolved in an aqueous methanolic ion pairing solution and quantitated by LC at 206 nm. Avian sera was combined with an equal volume of a pH 4 aqueous solution of ion pairing reagent and filtered to remove interfering proteins. DiazaCon was quantitated by LC. Mean recoveries for 500 and 2000 ppm fortified feed were 89.1 and 91.0%, …

The Strange Races On The Hereford Mappa Mundi: An Investigation Of Sources, John H. Chandler

Masters Theses

The Hereford Mappa Mundi, a thirteenth-century world map, includes mention of fifty-four strange races. Many of the races can be found in three earlier sources: Pliny's Naturalis historia, Solinus's Collectanea rerum memorabilium, and Isidore's Etymologiae. By comparison to these three sources, the works used by the author of the map will be made clear.

This study provides an edition of all the inscriptions relating to these races, and compares them to excerpts relating to the races from the three above sources, as well as St. Augustine's De civitate Dei and Pomponius Mela's De chorographia. Translations …

The Hormesis Challenge For Environmental Health Regulators, Michael S. Baram

Faculty Scholarship

The hormesis hypothesis provides that human, animal or plant exposure to a low external dose of a hazardous chemical substance or physical agent may have beneficial health outcomes'. For example, human exposure to a precisely defined, low external dose of a carcinogenic pollutant in the workplace or ambient environment may lead to an internal dose or concentration, which stimulates a dormant defense mechanism that inhibits the growth of tumors.

Development And Characterization Of Monoclonal Antibodies Directed Against Yaba-Like Disease Virus, Scott Haller

Masters Theses

The hybridoma technique has been used for the production of monoclonal antibodies (mAb) directed against yaba-like disease virus (YLDV). Spleen cells, obtained from female BALB/c mice immunized with YLDV, were fused with P3x63.Ag8.653 myeloma cells and hybrids were selected. Hybridoma clones were screened for production of anti-YLDV antibodies by Indirect Immunofluorescence (IF) microscopy. Positive hybridoma clones were recloned via limiting dilution and characterized. A single clone (H12) has been selected that specifically reacted with YLDV infected cells and not uninfected cells. Immunodiffusion technique determined H12 monoclonal antibody as an IgG1 isoptype immunoglobulin. H12 antibodies recognized a late YLDV protein, and …

Football Yobbery: The Social Organization Of European Soccer, Pakky M. Gerkin

Masters Theses

This study is an investigation of European football fans, known as hooligans. For this research, I went to the European Football Championships in the summer of 2000. During a two-month field research project, I observed the soccer games and the many fans who gathered for the tournament. In the course of the research, I spoke with several individuals and explored the existing literature in the sociology of sport. This work has been created through a combination of my own ethnographic work, and an extensive literature review. I have attempted to interweave both my own experiences and those of others to …

Phylogenetic Relationships Within Cation Transporter Families Of Arabidopsis, Pascal Mäser, Sébastien Thomine, Julian I. Schroeder, John M. Ward, Kendal Hirschi, Heven Sze, Ina N. Talke, Anna Amtmann, Frans J.M. Maathuis, Dale Sanders, Jeff F. Harper, Jason Tchieu, Michael Gribskov, Michael W. Persans, David E. Salt, Sun A. Kim, Mary Lou Guerinot

Dartmouth Scholarship

Uptake and translocation of cationic nutrients play essential roles in physiological processes including plant growth, nutrition, signal transduction, and development. Approximately 5% of the Arabidopsis genome appears to encode membrane transport proteins. These proteins are classified in 46 unique families containing approximately 880 members. In addition, several hundred putative transporters have not yet been assigned to families. In this paper, we have analyzed the phylogenetic relationships of over 150 cation transport proteins. This analysis has focused on cation transporter gene families for which initial characterizations have been achieved for individual members, including potassium transporters and channels, sodium transporters, calcium antiporters, …

Sart, A Repressor Of Α-Hemolysin In Staphylococcus Aureus, Katherine A. Schmidt, Adhar C. Manna, Steven Gill, Ambrose L. Cheung

Dartmouth Scholarship

In searching the Staphylococcus aureus genome, we found several homologs to SarA. One of these genes, sarT, codes for a basic protein with 118 residues and a predicted molecular size of 16,096 Da. Northern blot analysis revealed that the expression of sarT was repressed by sarA and agr. An insertion sarT mutant generated in S. aureus RN6390 and 8325-4 backgrounds revealed minimal effect on the expression of sarR and sarA. The RNAIII level was notably increased in the sarT mutant, particularly in postexponential-phase cells, while the augmentative effect on RNAII was less. SarT repressed the expression of alpha-hemolysin, as determined …