Digital Commons Network^™

Modeling Virtue, Chuck Huff

Intersections

No abstract provided.

Europe's Evolving Regulatory Strategy For Gmos—The Issue Of Consistency With Wto Law: Of Kine And Brine, Robert L. Howse, Petros C. Mavroidis

Faculty Articles

This Essay deals with one question: If challenged, how would regulatory restrictions on genetically modified organisms (”GMOs”) be judged by a World Trade Organization (”WTO”) adjudicating body. Many of the controversies about the effect of WTO law on domestic regulation have been influenced by the view that the law as it stands may well impede the ability of governments to regulate new and uncertain risks to health and the environment. The result in the Beef Hormones case is often cited for this proposition. In this Essay we aim to show that, contrary to an increasingly widespread popular perception, if WTO …

Plant Patent Law: The Federal Circuit Sows The Seed To Allow Agriculture To Grow, Andrew F. Nilles

Land & Water Law Review

No abstract provided.

The In Houses Of Deceits: Science, Forensic Science, And Evidence - An Introduction To Forensic Evidence, Terrence F. Kiely

Land & Water Law Review

No abstract provided.

A Guide To Permitting Confined Animal Feeding Operations In Wyoming, Rachel Jay Smith

Land & Water Law Review

No abstract provided.

Crop Watch No. 2000-05, April, 14, 2000, Lisa Brown Jasa

Crop Watch (1994–2005)

Briefs..........42

Plant Pathology Changes..........42

Drought Update..........43

Alfalfa, Clover Weevils..........44

Preemergence Weed Control Strategies..........46

Avoiding Developing of Resistant Weeds..........47

Spartan Approved..........48

USDA Resources..........48

Crop Watch No. 00-11, May 26, 2000, Lisa Brown Jasa

Crop Watch (1994–2005)

Field Updates..........90

Corn Rootworms..........92

ECP Moth Flight..........92

Replant Option..........93

Wheat Tour..........93

Late Alfalfa..........94

Barley Yellow Dwarf..........95

Spring Black Stem..........95

Soybean Development..........96

Corn Insect Guide..........97

Seed Coating..........98

Crop Watch No. 2000-17, July 21, 2000, Lisa Brown Jasa

Crop Watch (1994–2005)

Grape, Small Fruit Field Day..........146

Field Update..........146

Mobile Nurseries Detect New Dry Bean Rust Races..........148

Plant and Pest Clinic Update..........148

Two Fungicide Options for Bean Rust..........149

Haskell Ag Lab Field Day..........149

Check Corn Roots..........150

Crop Watch No. 2000-19, August 4, 2000, Lisa Brown Jasa

Crop Watch (1994–2005)

Field Updates..........161

Drought, Climate Assessment..........163

Strategic Irrigation..........164

Soybean Field Days..........166

Biotech Field Day..........166

Crop Update..........166

Dry Bean Field Day..........167

Diagnostics Report..........167

Sustainable Ag Tours..........168

Crop Watch No. 2000-22, September 15, 2000, Lisa Brown Jasa

Crop Watch (1994–2005)

Crop Updates..........190

Market Journal Monday..........191

Avoiding Wheat Diseases..........192

Late Season Irrigations..........193

Nitrogen Stalk Test..........194

Crop Condition..........194

Clean, Treat Bins..........195

Aerating Stored Grain..........196

Diagnostic Clinic Update..........196

Wheat Planting Issues..........197

Starlings. Wildlife Damage Management Series, J. A. Lynch, Terry A. Messmer

Wildland Resources Faculty Publications

No abstract provided.

Calcitonin Gene-Related Peptide Decreases Expression Of Hla-Dr And Cd86 By Human Dendritic Cells And Dampens Dendritic Cell-Driven T Cell- Proliferative Responses Via The Type I Calcitonin Gene-Related Peptide Receptor, John A. Carucci, Ralf Ignatius, Yang Wei

Publications

These studies were performed to establish whether functional receptors for calcitonin gene-related peptide (CGRP) are present on human dendritic cells (DCs) and to investigate potential immunomodulatory effects of CGRP on DCs other than Langerhans cells. Reverse transcriptase-PCR revealed expression of mRNA for a type 1 CGRP receptor by mature and immature blood- derived DCs. Sequence analysis confirmed the identity of the type 1 CGRP receptor (CGRP-R1). Addition of CGRP (10^-7 M) to mature and immature DCs resulted in mobilization of intracellular calcium. Treatment of immature DCs with CGRP (10^-7 M), before and after maturation in monocyte-conditioned medium, resulted …

Dendritic Cells, Infected With Vesicular Stomatitis Virus-Pseudotyped Hiv-1, Present Viral Antigens To Cd4+ And Cd8+ T Cells From Hiv-1-Infected Individuals, Angela Granelli-Piperno, Lei Zhong, Patrick Haslett

Publications

Nonreplicating vectors are being considered in HIV-1 vaccine design. However, nonreplicating viruses are typically weak immunogens, leading to efforts to target the vaccine to mature dendritic cells (DCs). We have studied a single-cycle form of HIV-1, prepared by pseudotyping envelope-defective HIV-1 plasmids with the envelope from vesicular stomatitis virus (VSV) G protein (VSV-G), to which most humans lack preexisting immunity. The nonreplicating, VSV/HIV-1 efficiently infected the immature stage of DC development, in this case represented by monocytes cultured with GM-CSF and IL-4. A majority of the cells reverse transcribed the HIV-1 RNA, and a minority expressed gag protein. The infected …

Information Encoding By Individual Neurons And Groups Of Neurons In The Primary Visual Cortex, Daniel Salo Reich

Student Theses and Dissertations

How is information about visual stimuli encoded into the responses of neurons in the cerebral cortex? In this thesis, I describe the analysis of data recorded simultaneously from groups of up to eight nearby neurons in the primary visual cortices of anesthetized macaque monkeys. The goal is to examine the degree to which visual information is encoded into the times of action potentials in those responses (as opposed to the overall rate), and also into the identity of the neuron that fires each action potential (as opposed to the average activity across a group of nearby neurons). The data are …

Dynamics Of Dna Breathing And Folding For Molecular Recognition And Computation, Gregoire Bonnet

Student Theses and Dissertations

This thesis is centered on the development of the molecular beacon, as a new DNA probe for DNA genotyping, DNA computation and biophysical studies of DNA conformations. Molecular beacons are single-stranded DNA molecules that form a stem-and-loop structure. A fluorophore and a quencher are grafted at their two ends to report their conformations: when the molecular beacon is closed, fluorophore and quencher are held in close proximity and the fluorescence is quenched; when the molecular beacon is open, fluorophore and quencher are far apart, and the fluorescence is restored. Molecular beacons are ideal DNA probes coupling conformational switch with fluorescence …

The Brain Invaders: Widespread Neuronal Dispersion In Developing And Adult Mammalian Brain, Hynek Wichterle

Student Theses and Dissertations

Cell migration is the principal determinant of the final brain cytoarchitecture. However, we have only limited knowledge about the migratory pathways and mechanisms utilized during brain development. In my thesis I present new and unexpected findings about neuronal migration in the developing forebrain. I analyzed and characterized a novel type of neuronal migration, so called tangential chain migration that was first identified in the subventricular zone (SVZ) in the adult mouse brain. I developed an in vitro migration assay using Matrigel as a substrate, which allowed me to analyze dynamics and mechanism of SVZ cell translocation. I demonstrated that neurons …

Structure-Function Studies On Human Epithelial Cystic Fibrosis Chloride Channels Expressed In Xenopus Laevis Oocytes, Laszlo Csanady

Student Theses and Dissertations

The cystic fibrosis transmembrane conductance regulator (CFTR) Cl^- channel is an ATP-binding cassette protein, comprising two transmembrane domains, two nucleotide binding domains (NBD1, NBD2) and a regulatory (R) domain. Channel gating is controlled by R-domain phosphorylation and by ATP binding and/or hydroysis at the NBDs. Exon 13 of the CFTR gene encodes residues 590 to 830, originally ascribed to the R domain. Here, CFTR channels were severed near likely N- or C-terminal boundaries of NBD1 or the R domain. Channel activity, assayed via two-microelectrode voltage clamp monitored successful assembly of pairs of channel segments as the sever point was …

A Niche For Adult Neurogenesis: Analysis Of Bmp Signaling And Transcriptional Profiles Of Adult Subventricular Zone Cells, Daniel A. Lim

Student Theses and Dissertations

Neurogenesis persists in restricted regions of the adult vertebrate brain. The largest region of adult neurogenesis is the subventricular zone (SVZ) of the lateral ventricle wall. Neural stem cells reside in the SVZ. The SVZ cell types and molecular signals necessary for this neurogenic niche were poorly understood. Here, I first demonstrate that astrocyte-like cells in the SVZ (type B cells) can self-renew and differentiate into mature brain cells. This data contributed to the identification of type B cells as the SVZ stem cell. In vivo, all SVZ cell types are in direct contact with type B cells. By reconstituting …

A Need To Know Basis: Record Keeping, Information Access, And The Uniform Status Of Children Of Assisted Conception Act, Amy Shelf

UC Law Journal

This note examines the delicate legal issues surrounding recent medical advances in reproductive technology, which have dramatically transformed the way humans reproduce. The ability to manipulate fertility raises difficult ethical issues, particularly when embryo and gametes donors choose to remain anonymous. The note addresses the current legal system's unsuccessful attempts at dealing with requests for information made by the offspring created through these new methods. The author analyzes the Uniform Status of Children of Assisted Conception Act, and, while agreeing with the Act's goal of putting the rights of children to the fore, also notes its failure to address record-keeping …

Stopping Hate Without Stifling Speech: Re-Examining The Merits Of Hate Speech Codes On University Campuses, Catherine B. Johnson

Fordham Urban Law Journal

This Note explores legislative attempts to help reduce incidents of hate speech on university campuses. It begins by analyzing the rise in hate speech codes at public universities and examining two U.S. Supreme Court decisions in R.A.V. v. City of St. Paul and Wisconsin v. Mitchell. The author argues that a hate speech code that implements forward-looking, long-term education objective would work towards stopping hate on campus without violating students' First Amendment rights. This Note reaches the conclusion that a narrowly drawn hate speech code based on recognized First Amendment exceptions, implemented along with with education initiatives, could facilitate the …

Second-Parent Adoption, Patricia J. Falk

Law Faculty Articles and Essays

The topic of this article is second-parent adoption. I hope to accomplish four things in my discussion. First, I will define second-parent adoption and give some reasons that it is desirable for both parents and children. Second, I will summarize the state of the law in terms of legislative enactments and case law in the United States. Third, I will discuss the role of social science in second-parent adoption cases. Finally, I will discuss some of the implications of recognizing second-parent adoptions.

Conceptualization Of Post-Traumatic Stress Disorder : Differences By Trauma Type And Gender, Tracy Muklewicz

Honors Capstones

Posttraumatic Stress Disorder has carried various implications for clinicians, particularly in the areas of gender and trauma type. Extensive literature review provides indication that individual research is fairly restricted to highly specific types of PTSD symptoms and presentations, which could limit the overall effectiveness of the disorder as a diagnostic tool. A history of PTSD as a diagnosis is presented. Three types of trauma are discussed in a research setting: Crime victims, military personnel, and gender non-specific traumas. Each study is reviewed in light of future directions for PTSD research to make the diagnostic category less ambiguous and more applicable …

The Isolation Of The Antizyme Inhibitor Protein, Donald F. Ellison

Honors Capstones

The polyamines, spermidine, spermine and its diamine precursor putrescine are required for proper cell development. An excess of polyamines causes can cause tumor formation, or apoptosis. Ultimately, understanding and having the ability to control the polyamine pathway may provide an opportunity to repress tumor development. The polyamine pathway has a precise feed back system that involves antizyme inhibitor (AZI). Yet, the role AZI plays in the polyamine pathway is poorly understood. This is due to the inability to account for its presence in polyamine analysis protocols. The first step to rectifying this problem is to isolate and purify the AZI …

Optimal Assay Conditions For Odc-Antizyme Interaction, Jennifer Cain

Honors Capstones

Polyamines are essential for life and are associated with cell cycle and development. Excess polyamine production occurs during tumor formation and is one possible target for chemopreventative and chemotherapeutic treatment. One enzyme, ornithine decarboxylase (ODC), plays a key role in polyamine biosynthesis. Among other regulators, the protein antizyme (Az) limits polyamine levels in the cell. It binds ODC and renders it unable to produce polyamines. The mechanism by which ODC and Az interact is unknown and is explored in this study. It is known that ODC and Az have high affinity for one another, but the reason for the basal …

Is There A Pink Slip In My Genes? Genetic Discrimination In The Workplace, Paul Steven Miller, Lawrence O. Gostin

Journal of Health Care Law and Policy

No abstract provided.

Genetic Discrimination: Why Bragdondoes Not Ensure Protection, Laura F. Rothstein

Journal of Health Care Law and Policy

No abstract provided.

Adverse Impact Of Predisposition Testing On Major Life Activities: Lessons From Brca 1/2testing, Katherine A. Schneider

Journal of Health Care Law and Policy

No abstract provided.

Activity Of Atdrm1 Promoters In Transgenic Arabidopsis Thaliana, Mary G. Dykas

Honors Capstones

The focus of this work involves the molecular regulation of dormancy in plants. This includes the analysis of genes that are activated when cells stop growing. Dormancy is the temporary arrest of cell growth as well as a group of changes that aid the plant in surviving adverse conditions. There are hormones involved in this process and their significance helps to demonstrate that dormancy is an active physiological process that requires altered levels of gene expression. Dormant plants have been found to contain unique patterns of gene expression, as well as protein synthesis. Additionally, dormant plants have unique processes such …

Re-Orienting Law And Sexuality , Ratna Kapur, Tayyab Mahmud

Cleveland State Law Review

This symposium issue of the Cleveland State Law Review emerges from the Reorienting Law and Sexuality Conference hosted by Cleveland-Marshall College of Law in October 1999. The symposium locates itself as a continuation of the discourse that surfaced in the American legal academy in 1979 with a symposium issue of the Hastings Law Review. It is a discourse that brings into sharp relief technologies of power and strategies of resistance that contend at all sites where law aims to regulate human sexuality. While the initiative of 1979 was further cultivated by other forums of knowledge production within the American legal …

A Child Conceived After His Father's Death: Posthumous Reproduction And Inheritance Rights - An Analysis Of Ohio Statutes, Cindy L. Steeb

Cleveland State Law Review

This Article will argue that the posthumous child and the rights and responsibilities relating to such a child, are directly related to the fundamental right to procreate, thus statutes must support rather than prohibit posthumous conception. It will argue that legislation must necessarily incorporate that right in determining issues and forming legislation related to the posthumous child. It will show that current legislation, both the various Uniform Codes and Ohio's Revised Code, is not sufficient to protect and provide for this new class of children. In reaching this conclusion, Part II of this Article will review the history of artificial …