Digital Commons Network^™

General Index

Louisiana Law Review

No abstract provided.

Life With God

Shabbat Shalom: A Journal for Jewish-Christian Reconciliation

No abstract provided.

Uncharged Trna Activates Gcn2 By Displacing The Protein Kinase Moiety From A Bipartite Trna-Binding Domain, Jinsheng Dong, Hongfang Qiu, Minerva Garcia-Barrio, James T. Anderson, Alan G. Hinnebusch

Biological Sciences Faculty Research and Publications

Protein kinase GCN2 regulates translation in amino acid–starved cells by phosphorylating eIF2. GCN2 contains a regulatory domain related to histidyl-tRNA synthetase (HisRS) postulated to bind multiple deacylated tRNAs as a general sensor of starvation. In accordance with this model, GCN2 bound several deacylated tRNAs with similar affinities, and aminoacylation of tRNA^Phe weakened its interaction with GCN2. Unexpectedly, the C-terminal ribosome binding segment of GCN2 (C-term) was required in addition to the HisRS domain for strong tRNA binding. A combined HisRS+C-term segment bound to the isolated protein kinase (PK) domain in vitro, and tRNA impeded this interaction. An activating mutation …

Cancer Surveillance Using Data Warehousing, Data Mining, And Decision Support Systems, Guisseppi A. Forgionne, Aryya Gangopadhyay, Monica Adya

Management Faculty Research and Publications

This article discusses how data warehousing, data mining, and decision support systems can reduce the national cancer burden or the oral complications of cancer therapies, especially as related to oral and pharyngeal cancers. An information system is presented that will deliver the necessary information technology to clinical, administrative, and policy researchers and analysts in an effective and efficient manner. The system will deliver the technology and knowledge that users need to readily: (1) organize relevant claims data, (2) detect cancer patterns in general and special populations, (3) formulate models that explain the patterns, and (4) evaluate the efficacy of specified …

Physiology Of A Microgravity Environment Invited Review: Microgravity And Skeletal Muscle, Robert H. Fitts, Danny R. Riley, Jeffrey J. Widrick

Biological Sciences Faculty Research and Publications

Spaceflight (SF) has been shown to cause skeletal muscle atrophy; a loss in force and power; and, in the first few weeks, a preferential atrophy of extensors over flexors. The atrophy primarily results from a reduced protein synthesis that is likely triggered by the removal of the antigravity load. Contractile proteins are lost out of proportion to other cellular proteins, and the actin thin filament is lost disproportionately to the myosin thick filament. The decline in contractile protein explains the decrease in force per cross-sectional area, whereas the thin-filament loss may explain the observed postflight increase in the maximal velocity …

Determination Of Phenols In Water Using Solid Phase Microextraction And Fourier Transform Infrared Spectroscopy And Measurement Of Distribution Constants For Solid Phase Microextraction Using A Successive Extraction Technique, Betsy J. Bannier

Theses and Dissertations

Solid phase microextraction (SPME) is an effective method for concentrating organic compounds prior to analysis by a variety of detection methods, including Fourier transform infrared spectroscopy (FTIR) and gas chromatography (GC). The first part of this work focused on the selection of an infrared-compatible solid phase that would partition phenols out of aqueous solutions. The criteria we employed dictated that potential solid phases be polar yet insoluble in water, have open regions in their IR spectra between 400-1200 cm·', 3010-3095 cm·', or 3200-3650 cm·' and be less than 200 μm thick.

Infrared spectra of a variety of proprietary epoxies and …

Nitrogen Budgets Of Phloem-Feeding Bark Beetles With And Without Symbiotic Fungi, Matthew P. Ayres, Richard T. Wilkens, Jonathan J. Ruel, María J. Lombardero, Erich Vallery

Dartmouth Scholarship

The nitrogen content of plant tissue is low relative to that of herbivores; as a consequence, dietary N can limit the growth and reproduction of herbivores and select for attributes that increase N acquisition. Bark beetles face a particularly severe challenge because the phloem that they consume is very low in nitrogen and phosphorus relative to their requirements. We quantified variation in the phloem concentrations of N and P in the host tree, Pinus taeda, and evaluated the following hypotheses regarding the role of symbiotic fungi in nutrient budgets of the herbivore Dendroctonus frontalis: D. frontalis experience variation …

Accounting For The Complexity Of Causal Explanations In The Wake Of An Environmental Risk, Lee Ann Kahlor, Sharon Dunwoody, Robert J. Griffin

College of Communication Faculty Research and Publications

In 1993, Milwaukee-area residents experienced a nationally publicized outbreak of cryptosporidium, a parasite, which infested the metropolitan drinking supply and sickened some 400,000 people. Using survey data gathered from 610 adult residents in the wake of that outbreak, this study looks at predictors of the complexity of people’s understanding of two causal components of the outbreak: 1) how the parasite got into the water supply and 2) how it causes illness once in the human body. Analysis of open-ended data indicated that, consistent with the knowledge gap hypothesis, socioeconomic status is a significant predictor of differences in explanatory complexity. And, …

High Efficiency Separation Of Microbial Aggregates Using Capillary Electrophoresis, J. M. Schneiderheinze, Daniel W. Armstrong, G. Schulte, David J. Westenberg

Chemistry Faculty Research & Creative Works

Recent advances in the technique of capillary electrophoresis have demonstrated fast, highly efficient separation of mixtures of intact microbes. This paper describes the application of this technique for the separation of microbial aggregates of Micrococcus luteus, Saccharomyces cerevisiae, or Alcaligenes faecalis. The aggregates of these microbes were resolved into several highly efficient peaks with analysis times under 10 min and efficiencies approaching 1 000 000 plates m-1 in some cases. A reproducible relationship was found between the electrophoretic mobility and the aggregation number or size of the cluster under a given set of experimental conditions. Often, cellular aggregation was reversible …

The Relationship Of Small Mammal Species To Habitat Variables In West-Central Georgia And East-Central Alabama, Patricia Maureen Kosky

Theses and Dissertations

The objective of this investigation was to assess the impact of environmental variables upon small mammal species distribution in 60 plots on Fort Benning, Muscogee and Chattahoochee Counties, Georgia and Russell County, Alabama. The small mammal fieldwork was carried out in December of 1994 through January of 1995. The vegetation was inventoried in June through October of 1995. During this period, 235 small mammals were trapped in a total of 5950 trap nights. A total of 10 small mammal species and 234 plant species were identified. The small mammal species abundance's were determined by using snap trapping along the plot …

A New Role For A Snare Protein As A Regulator Of The Ypt7/Rab-Dependent Stage Of Docking, Christian Ungermann, Albert Price, William Wickner

Dartmouth Scholarship

The homotypic fusion of yeast vacuoles occurs in an ordered cascade of priming, docking, and fusion. The linkage between these steps has so far remained unclear. We now report that Vam7p (the vacuolar SNAP-23/25 homolog) signals from the cis-SNARE complex to Ypt7p (the vacuolar Rab/Ypt) to initiate the docking process. After Vam7p has been released from the cis-SNARE complex by Sec18p-mediated priming, it is still required for Ypt7p-dependent docking and it needs Ypt7p to remain on the vacuole.

La Notion De Danger, Jean M. Kanellopoulos, David M. Ojcius

All Dugoni School of Dentistry Faculty Articles

Pendant de nombreuses années, les recherches en immunologie ont été centrées sur la réponse immunitaire adaptative, et la plupart des immunologistes considéraient que sa fonction principale était de faire la distinction entre soi et non soi. Plus récemment, plusieurs équipes ont proposé que la fonction principale du système immunitaire est en réalité d’éliminer les agents pathogènes. Or, c’est le système immunitaire inné, longtemps négligé, qui joue un rôle essentiel dans l’induction d’une réponse contre les microorganismes. Ce système réagit précocement aux infections, voire instantanément, puis il induit et oriente la réponse du système adaptatif. Plusieursthéories ont été élaborées pour expliquer …

Free Radical Production In Hypoxic Pulmonary Artery Smooth Muscle Cells, David W. Killilea, Raymond Hester, Ron Balczon, Pavel Babal, Mark N. Gillespie

University Faculty and Staff Publications

This study used an inexpensive and versatile environmental exposure system to test the hypothesis that hypoxia promoted free radical production in primary cultures of rat main pulmonary artery smooth muscle cells (PASMCs). Production of reactive species was detected by fluorescence microscopy with the probe 2', 7'-dichlorodihydrofluorescein, which is converted to the fluorescent dichlorofluorescein (DCF) in the presence of various oxidants. Flushing the airspace above the PASMC cultures with normoxic gas (20% O(2), 75% N(2), and 5% CO(2)) resulted in stable PO(2) values of approximately 150 Torr, whereas perfusion of the airspace with hypoxic gas (0% O(2), 95% N(2), and 5% …

Early Instar Growth And Survivorship In The Common Baskettail Dragonfly Epitheca Cynosura (Anisoptera: Corduliidae)., Bryan Arthur Reece

Electronic Theses and Dissertations

Egg masses of Epitheca cynosura were collected from Bays Mountain Park, Tennessee, USA, in June, 1999. Newly hatched individuals were placed into enclosures and sampled at scheduled time intervals throughout the summer. Enclosures were exposed to combinations of high and low densities and presence/absence of a second-year class E. cynosura predator. Survivorship, mean head widths, and mean dry masses were compared across treatments. Due to poor recovery of early-instar larvae, survivorship showed no significant differences in mortality among treatments. The predator present treatment caused significantly smaller head widths and dry masses only on days 42 and 55. The density treatment …

Characterization Of 50s Ribosomal Subunit Assembly Inhibition In Erythromycin Treated Escherichia Coli Cells., Jerry Edward Usary

Electronic Theses and Dissertations

Erythromycin has long been recognized for its ability to inhibit protein synthesis by interfering with mRNA translation on the bacterial ribosome. We have recently shown that erythromycin also inhibits the assembly of the 50S ribosomal subunit in growing bacterial cells. The nature of this assembly inhibition has been investigated using ³H-uridine pulse-chase labeling of control and erythromycin treated E. coli cells.

Subunit assembly was examined by sucrose gradient centrifugation of labeled cell lysates. Normal assembly kinetics of subunit assembly were observed in control cells at 37°C. Formation of the 30S subunit was completed by 7.5 minutes and assembly of …

Adult's Perceptions Of Children's Aggressive Play With Advertised And Non-Advertised Toys., Lori J. Klinger

Electronic Theses and Dissertations

This study examined adults’ perceptions of aggression in toys and toy commercials targeted toward young boys. The subjects, 262 undergraduate psychology students, completed the Buss/Perry Aggression Questionnaire and rated either a videotape of 10 boy-oriented toy commercials or slides of 10 non-advertised boy-toys. Parental status, exposure to an advertised versus non-advertised toy, and level of self-reported aggression were assessed to determine their relationship to perceptions of aggressiveness in a toy’s image and predicted play with the toy.

Univariate analyses of variance and paired sample t-tests were conducted. The results indicate that toys advertised in commercials are judged to portray more …

Baseline Susceptibility Of The Corn Earworm (Lepidoptera: Noctuidae) To The Cry1ab Toxin From Bacillus Thuringiensis, Blair D. Siegfried, Terrence A. Spencer, Jessica Nearman

Department of Entomology: Faculty Publications

Susceptibility to Cry1Ab toxin from Bacillus thuringiensis (Bt) was determined for 12 field populations of neonate corn earworm, Helicoverpa zea (Boddie), from the United States. Earworm larvae were exposed to artificial diet treated with increasing Bt concentrations, and mortality and growth inhibition were evaluated after 7 d. The range of variation in Bt susceptibility indicated by growth inhibition was very similar to that indicated by mortality. Although interpopulation variation in susceptibility to both proteins was observed, the magnitude of the differences was small (less than or equal to fivefold). These results suggest that the observed susceptibility differences reflect natural variation …

Nuclear Localization Of Turnip Crinkle Virus Movement Protein P8, Yuval Cohen, Feng Qu, Andreas Gisel, Thomas Jack Morris, Patricia Zambryski

Department of Plant Pathology: Faculty Publications

Turnip crinkle virus (TCV) is a single-stranded positive-sense RNA virus of the Carmovirus genus. Two of its five open reading frames (ORFs), encoding proteins of 8 and 9 kDa, are required for cell-to-cell movement of the virus. These movement proteins (MPs) were fused to green fluorescent protein (GFP) to determine their cellular localization. In protoplasts, p9-GFP, like GFP itself, is found throughout the cytoplasm, as well as in cell nuclei. In contrast, p8-GFP was confined to the cell nucleus. Similar localization patterns were observed when specific small peptide epitopes were fused to p8 and p9 proteins instead of GFP. The …

Utility Of The Mitochondrial Cytochrome Oxidase Ii Gene For Resolving Relationships Among Black Flies (Diptera: Simuliidae), K. P. Pruess, B. J. Adams, T. J. Parsons, X. Zhu, Thomas O. Powers

Department of Plant Pathology: Faculty Publications

The complete mitochondrial cytochrome oxidase II gene was sequenced from 17 black flies, representing 13 putative species, and used to infer phylogenetic relationships. A midge (Paratanytarsus sp.) and three mosquitoes (Aedes aegypti, Anopheles quadrimaculatus, and Culex quinquefasciatus) were used as outgroup taxa. All outgroup taxa were highly divergent from black flies. Phylogenetic trees based on weighted parsimony (a priori and a posteriori), maximum likelihood, and neighbor-joining (log-determinant distances) differed topologically, with deeper nodes being the least well-supported. All analyses supported current classification into species groups but relationships among those groups were poorly resolved. The majority of phylogenetic …

The Operative Treatment Of Full Thickness Cartilage Defects In The Knee Joint With Autologous Chondrocyte Transplantation, Christoph Erggelet, Matthias R. Steinwachs, Achim Reichelt

Saudi Medical Journal

OBJECTIVE: The high clinical and socio-economical impact of cartilage defects and chondral degeneration is well-known. After trauma or without a known etiology, often young patients suffer from pain and a loss of function leading into a decrease of physical activity and, more severe, into long term disability and unemployment. The clinical use of autologous chondrocyte transplantation was introduced in 1994 reporting the data of a pilot study. The objective of this study is to evaluate the efficacy of this method of surgery. METHODS: Autologous chondrocyte transplantation has been established in our department since 1995 for the treatment of large, full …

Knowledge And Practice Of Preventive Measures In Small Industries In Al-Khobar, Attia Z. Taha

Saudi Medical Journal

OBJECTIVE: The specific objective of this study was to assess the knowledge and practice of workers in small industries regarding preventive measures of occupational hazards. METHODS: Three workshops were randomly selected from each of the 8 types of industries in the industrial area. This gave a total sample of 24 workshops. From each of these, at least one worker was selected giving a total of 33 workers. All selected workers were interviewed using a standard questionnaire. A checklist on the conditions of the shop and availability of essential safety equipments was also designed. RESULTS: All workers were young non-Saudis. More …

Cephalometric Evaluation Of Craniofacial Variation In Normal Saudi Population According To Steiner Analysis, Nasser M. Al-Jasser

Saudi Medical Journal

OBJECTIVE: The objective of this study was to describe the craniofacial pattern of Saudi ethnic groups and to compare it with accepted standards for the caucasian population according to Steiner analysis. METHODS: Lateral cephalometric radiographs of 87 Saudi students (74 male and 13 females) with balanced harmonious faces and clinically acceptable permanent occlusion, aged 21-27 years old were used. A computer-aided cephalometric analysis was performed, and the mean values and standard deviations for the various cephalometric variables were obtained. RESULTS: A comparison of the results with the Steiner standards showed that the Saudis have relatively similar skeletal relationship and dentally …

A Plant Virus Vector For Systemic Expression Of Foreign Genes In Cereals, Il-Ryong Choi, Drake C. Stenger, Thomas Jack Morris, Roy C. French

Department of Plant Pathology: Faculty Publications

Inserts bearing the coding sequences of NPTll and P-glucuronidase (GUS) were placed between the nuclear inclusion b (Nlb) and coat protein (CP) domains of the wheat streak mosaic virus (WSMV) polyprotein ORF. The WSMV Nlb-CP junction containing the nuclear inclusion a (Nla) protease cleavage site was duplicated, permitting excision of foreign protein domains from the viral polyprotein. Wheat, barley, oat and maize seedlings supported systemic infection of WSMV bearing NPTII. The NPTII insert was stable for at least 18-30 days post-inoculation and had little effect on WSMV CP accumulation. Histochemical assays indicated the presence of functional GUS protein in systemically …

Emergence Of Third-Stage Larvae Of Umingmakstrongylus Pallikuukensis From Three Gastropod Intermediate Host Species, Susan K. Kutz, Eric P. Hoberg, Lydden Polley

Harold W. Manter Laboratory of Parasitology: Faculty Publications

We investigated the emergence of third-stage larvae (L3) of Umingmakstrongylus pallikuukensis from the slugs Deroceras laeve, Deroceras reticulatum, and the snail Catinella sp. in the laboratory and from D. laeve on the tundra. Third-stage larvae emerged from 8 of 8 D. laeve and 8 of 8 D. reticulatum housed at 20°C in darkness and from 9 of 10 D. laeve and 5 of 5 Catinella sp. housed at 21°C with 10-12 hours of light/day. Larvae emerged from D. laeve and D. reticulatum over a wide range of infection intensities (2-179 and 20-65, respectively), and the patterns of emergence …

Adult Survivors Of Family Violence And Abuse, Marcie De La Cruz

Theses and Dissertations - UTB/UTPA

The topic of family violence and abuse is a very sensitive issue. Yet, violence is a part of everyday life. Although people are constantly being bombarded by violent acts on television and in newspaper articles, family violence and abuse is a topic that is to a certain extent, taboo. Even with this taboo topic, family violence and abuse has been widely studied and researched; however, the majority of the research has concentrated on a quantitative aspect. Thus, this study looks at family violence and abuse through qualitative eyes. In the grand tradition of case studies and narratives, this qualitative study …

Induction Of Myosin Cross-Reactive Antibody And Cytolytic T Cell Responses In Mice With Streptococcus Pyogenes, Cynthia Ann Cunningham

Graduate Theses, Dissertations, and Problem Reports (ETD)

Impetigo and pharyngitis are two common suppurative infections in man elicited by Streptococcus pyogenes that lead to autoimmune complications in susceptible individuals. Although the underlying mechanisms for the onset of post-streptococcal autoimmunity have yet to be established, experimental information gained thus far suggests that the resultant pathology is a consequence of immunological cross-reactivity between streptococcal antigens, namely the anti-phagocytic factor M protein and host proteins, specifically myosin. Experimental animal model systems developed to date have predominantly relied on the immunization of adult animals with M protein emulsed in adjuvant. In the laboratory we have undertaken studies with mice to examine …

Quality And Postharvest Performance Of Cut Roses Grown In Root Media Containing Coal Bottom Ash, Marlene Karen Cross

Graduate Theses, Dissertations, and Problem Reports (ETD)

The vase life of roses grown in coal bottom ash (CBA)-amended media was evaluated. CBA is enriched in calcium, a nutrient implicated in delaying senescence. Four rose cultivars, Cara Mia, Dakota, Santa Fe and Pink Osiana, were grown (from started eye plants) in four media: a 50% CBA medium and a peat: vermiculite medium amended with calcitic and dolomitic lime (1:1) were used as "high calcium" media, whereas a 25% CBA medium and a peat: vermiculite medium amended with dolomitic lime only were used as "low calcium" media. Yield was not different for roses from different media, and a subjective …

The Law Of Armed Conflict As Soft Power: Optimizing Strategic Choice, Michael N. Schmitt

International Law Studies

No abstract provided.

Effects Of Acetaminophen On Estrogen-Responsive Alkaline Phosphatase In Ishikawa Endometrial Cancer Cells, Janet A. Dowdy

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study examines the effect of acetaminophen (APAP) on the estrogen-responsive gene alkaline phosphatase in Ishikawa endometrial cancer cells. Basal levels of alkaline phosphatase activity were significantly inhibited in cells treated with 0.03, 0.1, 0.3 and 1mM APAP compared to control. Alkaline phosphatase activity induced with 1nM estradiol was significantly inhibited in a concentration dependent manner by 0.0.1, 0.3 and 1mM APAP. APAP did not directly inhibit the activity of alkaline phosphatase at any of the concentrations tested. Increasing estradiol concentrations (0.01, 0.1 and 1nM) did not alter the level of inhibition of alkaline phosphatase activity by 0.1, 0.3 or …

Assessing West Virginia Nipf Owner Characteristics And Preferred Assistance Topics, Daniel Joseph Magill

Graduate Theses, Dissertations, and Problem Reports (ETD)

Four hundred and fifty-one Non-Industrial-Private-Forest (NIPF) owners (49% response rate) in West Virginia responded to a survey of their forestry assistance needs. Most of the socioeconomic characteristics of the respondents, their reasons for owning the property, the types of activities they were engaged in on the property and the agencies that provided assistance by themselves significantly (Chi2 & ANOVA) differentiated those interested and not interested in obtaining assistance. However, when all 39 factors were considered together (Logistic Regression) only a small number of these factors were needed to explain the difference between landowners wanting and not wanting a specific assistance …