Digital Commons Network^™

2000 Annual Report, The Jackson Laboratory

Annual Reports

No abstract provided.

Resurgent Malaria At The Millennium Control Strategies In Crisis, J. Kevin Baird

United States Public Health Resources

Completion of the Panama Canal in 1914 marked the beginning of an era of vector control that achieved conspicuous success against malaria. In 1955 the World Health Organization (WHO) adopted the controversial Global Eradication Campaign emphasising DDT (dichlorodiphenyltrichloroethane) spraying in homes. The incidence of malaria fell sharply where the programme was implemented, but the strategy was not applied in holoendemic Africa. This, along with the failure to achieve eradication in larger tropical regions, contributed to disillusionment with the policy. The World Health Assembly abandoned the eradication strategy in 1969. Aresurgence of malaria began at about that time and today reaches …

Assessing Drug Sensitivity Of Plasmodium Vivax To Halofantrine Or Choroquine In Southern, Central Vietnam Using An Extended 28-Day In Vivo Test And Polymerase Chain Reaction Genotyping, W. R.J. Taylor, Doan Hanh Nhan, Nguyen Dieu Thuong, Tran Thi Uyen, D. J. Fryauff, E. Gomez-Saladin, K. C. Kain, Le Dinh Cong, J. Kevin Baird

United States Public Health Resources

Chloroquine-resistant Plasmodium vivax malaria is emerging in Oceania, Asia, and Latin America. We assessed the drug sensitivity of P. vivax to chloroquine or halofantrine in two villages in southern, central Vietnam. This area has chloroquine-resistant Plasmodium falciparum but no documented chloroquine-resistant P. vivax. Standard dose chloroquine (25 mg/kg, over 48 hours) or halofantrine (8 mg/kg, 3 doses) was administered to 29 and 25 patients, respectively. End points were parasite sensitivity or resistance determined at 28 days. Of the evaluable patients, 23/23 100% (95% confidence interval [CI] 85.1–100) chloroquine and 21/24 (87.5%) (95% CI 67.6–97.3) halofantrine-treated patients were sensitive. Three halofantrine …

Lessons Learned In Applying The U.S. Epa Proposed Cancer Guidelines To Specific Compounds, Melvin E. Andersen, M. Elizabeth Meek, Gary A. Boorman, David J. Brusick, Samuel M. Cohen, Yvonne P. Dragan, Clay B. Frederick, Jay I. Goodman, Gordon C. Hard, Ellen J. O'Flaherty, Denise E. Robinson

United States Public Health Resources

An expert panel was convened to evaluate the U.S. Environmental Protection Agency’s “Proposed Guidelines for Carcinogen Risk Assessment” through their application to data sets for chloroform (CHCl₃) and dichloroacetic acid (DCA). The panel also commented on perceived strengths and limitations encountered in applying the guidelines to these specific compounds. This latter aspect of the panel’s activities is the focus of this perspective. The panel was very enthusiastic about the evolution of these proposed guidelines, which represent a major step forward from earlier EPA guidance on cancer-risk assessment. These new guidelines provide the latitude to consider diverse scientific data …

Lessons Learned In Applying The U.S. Epa Proposed Cancer Guidelines To Specific Compounds, Melvin Andersen, M. Elizabeth Meek, Gary Boorman, David Brusick, Samuel Cohen, Yvonne Dragan, Clay Frederick, Jay Goodman, Gordon Hard, Ellen O'Flaherty, Denise Robinson

United States Public Health Resources

An expert panel was convened to evaluate the U.S. Environmental Protection Agency’s “Proposed Guidelines for Carcinogen Risk Assessment” through their application to data sets for chloroform (CHCl₃) and dichloroacetic acid (DCA). The panel also commented on perceived strengths and limitations encountered in applying the guidelines to these specific compounds. This latter aspect of the panel’s activities is the focus of this perspective. The panel was very enthusiastic about the evolution of these proposed guidelines, which represent a major step forward from earlier EPA guidance on cancer-risk assessment. These new guidelines provide the latitude to consider diverse scientific data …

Washington University Magazine And Alumni News, Summer 2000

Washington University Magazine

No abstract provided.

Broadening The Horizons Of Chinese History, Thomas D. Curran Ph.D.

History Faculty Publications

Book review by Thomas D. Curran.

Huang, Ray. Broadening the Horizons of Chinese History. Armonk: M. E. Sharpe, 1999.

The National Honors Report, Volume Xxi, Number 1/2, Spring/Summer 2000

The National Honors Report

First, The Cover - taken from Damir Sinovcic's mural based on da Vinci's "Man as a Measure of All Things," with special thanks to Lydia Daniel (Director of Honors Institute, Hillsborough Community College); cover design by Stephanie Lucas with Jon Wszalek, and thanks to Joyce Wszalek (Associate Director, James Madison University VA).

1. "The Story Behind" by Lydia Daniel … 1 The director of the Honors Institute shares how the mural came to be. With comments from Damir Sinovcic, the artist.

2. "About Damir's Mural" by Margaret Brown … 2 Students and faculty awed by Damir Sinovcic's mural. Many other …

Tributes: Health, Heart And Mind: The Contributions Of Richard A. Posner To Health Law And Policy, Diane P. Wood

Articles

No abstract provided.

The Design And Interpretation Of Contracts: Why Complexity Matters, Eric A. Posner, Karen Eggleston, Richard Zeckhauser

Articles

No abstract provided.

Past-Dependency, Pragmatism, And Critique Of History In Adjudication And Legal Scholarship, Richard A. Posner

Articles

Using Nietzsche's great essay on the uses and disadvantages of history for life as his jumping-off point, Judge Posner examines the utility of the study of history for adjudication and legal scholarship. He argues, following Nietzsche; that the wrong kind of historical study can be very bad for "life " including law, while the right kind-the kind deployed by a pragmatic judge or a policy-oriented legal scholar-may deviate from literal accuracy in the direction of a rhetorical and imaginative narrative of historical events that can be constructively employed in a forward-looking approach to legal problems.

The Public Choice Threat (Reviewing Robert D. Cooter, The Strategic Constitution (2000) & Dennis C. Mueller, Constitutional Democracy (1996)), Saul Levmore

Articles

No abstract provided.

Hard Bargains And Real Steals: Land Use Exactions Revisited, Lee Anne Fennell

Articles

No abstract provided.

Echoes From The Hill, Southwestern Oklahoma State University Office Of Institutional Advancement And Alumni

Echoes from the Hill

No abstract provided.

An Interdisciplinary Introduction To Legal Transparency: A Tool For Rational Development, Willian B.T. Mock

Penn State International Law Review (1982 - 2011)

No abstract provided.

Increasing Parental Involvement Through Internet Instruction, David Allen Chaplin

All Graduate Projects

The purpose of the project was to develop a curriculum of Internet instruction for parents of Washington Middle School students. Through a review of the current literature it was found that the recurring lack of communication between parents, students and educators was identified as a barrier for involving families in their students' education. To overcome this barrier four sessions of instruction and practice were developed to increase the families' ability to communicate with their children's educators. The sessions introduce the basic layout and function of computers, the Internet, using email for communication, skills vital for finding information on the internet, …

A Coordinator's Manual For The Recruitment And Training Of Volunteer, Elementary Level Tutors In Reading And Mathematics, Lara Cole

All Graduate Projects

The purpose ofthis project was to develop a manual for the coordination of a volunteer, elementary level tutoring program. To accomplish this purpose a review of related literature was conducted. Additionally, related information from selected resources was obtained and analyzed.

A Comparison Of Reading Comprehension And Problem Solving Abilities, Darren A. Cooper

All Graduate Projects

Recommendations of the National Council of Teachers of Mathematics and the Washington State Commission on Student Learning Essential Academic Requirements are addressed. Reading comprehension and problem solving skills of 9th grade students at Zillah High School are compared to see if a correlation between these two abilities exists. Recommendations for creating and implementing a curriculum are given.

The Art Of Science: An Integrative Curriculum, Lisa Kay Dorsing

All Graduate Projects

This project shows the development of an integrated, interdisciplinary curriculum which combines the visual arts with the physical, life and health sciences at the sixth grade level. The integrated curriculum sample identifies and aligns with the Essential Academic Learning Requirements of Washington state. In addition, the sample lessons maintain the integrity of both art and science, the two subjects being integrated, demonstrating how integration can take place while allowing both subjects to maintain their value as individual disciplines. The review of literature gives background on issues revolving around integration in general, as well as integration involving the arts.

A Model Athletic Director's Handbook For Sunnyside High School, Brian P. Hart

All Graduate Projects

The purpose of this project was to develop a model athletic director's handbook of procedures/practices for use in guiding athletic program development at Sunnyside High School. To accomplish this purpose, a review of related research and literature was conducted. Additionally, related information from selected school districts was obtained and analyzed.

An Administrative Model For A Bilingual Education Program For Middle-Level Students In Taiwan, Po-Chun Hsieh

All Graduate Projects

The purpose of this project was to develop an administrative model for a bilingual education program for middle-level students in Taiwan. To accomplish this purpose, a review of related literature was conducted. Additionally, selected materials were obtained adapted for use.

Helping School Administrators Involve Hispanic Parents In Their Children's Education, Ricardo Iniguez

All Graduate Projects

The purpose of this project was to help school administrators more effectively involve Hispanic parents in the education of their children both at school and in the home. To accomplish this task, principals and parents from four heavily impacted Hispanic school districts were interviewed. Research was undertaken of pertinent literature and a study of parent involvement programs was also included. Based upon analysis of interviews and research a conceptual framework on how to involve Hispanic parents in the education of their children was developed along with examples of specific programs and activities.

Integrating Writing To Enhance Mathematical Skills At The Elementary Level, Kendra J. Kupp

All Graduate Projects

The recommendations of the National Council of Teachers of Mathematics and the Washington State Commission on Student Learning Essential Academic Requirements are addressed. The benefits of integrating mathematics and writing are studied. Integrated activities and materials for a first and second grade mathematics curriculum are developed. Recommendations for implementing the project are given.

The Mathematics Of Sound: Integrating Music Into A Math Curriculum, Shawn William Meacham

All Graduate Projects

The purpose of this project was to develop prototype lesson plans that connects and integrates musical and mathematical concepts at the 5th grade level. Both musical and mathematical concepts can be enhanced when studying the correlation between the two subjects. This project will provide lesson plans and activities using the Washington State Essential Academic Leaming Requirements as a basis for the concepts being taught. The goal of the project is to inspire teachers to use integration throughout the curriculum. An integrated curriculum develops and supports the coherence of ideas and concepts taught within our schools. By fostering our natural instinct …

Real World Mathematics Skills Within The Elementary Resource Classroom, Stacy Schilperoort

All Graduate Projects

A project, including activities, to assist elementary special education teachers in incorporating real world mathematics skills within their own resource classrooms was developed. A literature review of current research on the topic of real world math skills in schools around the country is also included as part of this project. The literature indicates that students with learning disabilities might benefit and become better prepared for the future as adult citizens by receiving an education that includes math activities that relate to the real world outside the classroom walls.

Studies Of Tryptophans In Membrane- Spanning "Walp" Peptides By Deuterium Nmr Spectroscopy, Nichole Reed

Inquiry: The University of Arkansas Undergraduate Research Journal

WALP pep tides of sequence acetyl-Gly-Trp-Trp-(Leu-Ala)-Trp-Trp-Ala-ethanolamine insert into lipid bilayers as membrane-spanning a-helices and modulate the lipid phase behavior as functions of n and the lipid acyl chain length. A key feature of the WALP peptides is the positioning of tryptophan (Trp) indole rings at the membrane/water interface. For the examples WALP19 with n = 6.5 and WALP23 with n = 8.5, we have labeled individual indoles with deuterium and incorporated the labeled peptides in oriented, hydrated bilayers of Dimyristoyl-phosphatidylcholine (DMPC). Deuterium NMR spectra from these samples show sharp resonances when the membrane normal is aligned either parallel (Beta = …

Design, Implementation, And Evaluation Of Virtual Interface Architecture For Power Pc Machines, Ben Mckenzie

Inquiry: The University of Arkansas Undergraduate Research Journal

The Virtual Interface Architecture (VIA) standard is a low-latency protocol that was designed for use in high-performance networks. VIA improves performance by reducing overhead in messaging. This research has two components. The first part of this research project is the development of a new tool for measuring the performance of a VIA implementation and comparing it to the more traditional high-overhead protocols used on the Internet. The development of the tool represents a significant contribution in and of itself, since the tool has been put into the public domain and will likely become useful by Lima users, both for measuring …

Student Expression: The Legacy Of Tinker In The Wake Of Columbine, Edward T. Ramey

Denver Law Review

No abstract provided.

Geometry And Mathematics Through Bridge Building, J. Joyner

Journal of Mathematics and Science: Collaborative Explorations

No abstract provided.

Helping Change Of Career Individuals To Prepare To Become Secondary Mathematics Teachers, K. Goldberg

Journal of Mathematics and Science: Collaborative Explorations

This article describes the development and content of a special introductory course developed and offered at New York University for change of career individuals entering the field of mathematics and science teaching at the graduate rather than the undergraduate level. With a critical shortage of qualified mathematics and science teachers at the secondary level being exacerbated in urban public schools, such as those in New York City, by high attrition rates during the first few years of teaching, it is important to find and encourage new populations of potential teachers. One such population is that of career changers, and the …